Hubert T Kim

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Chondrocyte apoptosis: implications for osteochondral allograft transplantation
    Hubert T Kim
    Orthopedic Surgery Section, San Francisco VA Medical Center, 4150 Clement Street 112, San Francisco, CA 94121, USA
    Clin Orthop Relat Res 466:1819-25. 2008
  2. ncbi A mouse model of massive rotator cuff tears
    Xuhui Liu
    San Francisco Veterans Affairs Medical Center, Building 2, Room 639, 4150 Clement Street, San Francisco, CA 94121, USA
    J Bone Joint Surg Am 94:e41. 2012
  3. ncbi Evaluation of Akt/mTOR activity in muscle atrophy after rotator cuff tears in a rat model
    Xuhui Liu
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, Califronia, USA
    J Orthop Res 30:1440-6. 2012
  4. ncbi Chondrocyte apoptosis after simulated intraarticular fracture: a comparison of histologic detection methods
    Alexis C Dang
    Department of Orthopaedic Surgery, University of California, 500 Parnassus Avenue, MU320 W, Box 0728, San Francisco, CA 94143, USA
    Clin Orthop Relat Res 467:1877-84. 2009
  5. ncbi Thermal stress potentiates bupivacaine chondrotoxicity
    Samantha L Piper
    Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California, U S A
    Arthroscopy 28:1246-1254.e1. 2012
  6. ncbi Comparison of ropivacaine and bupivacaine toxicity in human articular chondrocytes
    Samantha L Piper
    J Bone Joint Surg Am 90:986-91. 2008
  7. ncbi Admitting service and morbidity and mortality in elderly patients after hip fracture: finding a threshold for medical versus orthopedic admission
    James M Mok
    Department of Orthopaedic Surgery, University of California, San Francisco, 94143 0728, USA
    Am J Orthop (Belle Mead NJ) 39:80-7. 2010
  8. ncbi Effects of local anesthetics on articular cartilage
    Samantha L Piper
    Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California, USA
    Am J Sports Med 39:2245-53. 2011
  9. ncbi Functional motor recovery after peripheral nerve repair with an aligned nanofiber tubular conduit in a rat model
    Jenny Jin
    San Francisco VA Medical Center, 4150 Clement Street Box 112, San Francisco, CA 94121, USA
    Regen Med 7:799-806. 2012
  10. ncbi Imaging longitudinal changes in articular cartilage and bone following doxycycline treatment in a rabbit anterior cruciate ligament transection model of osteoarthritis
    James R Pinney
    UC Berkeley UCSF Graduate Program in Bioengineering, San Francisco, CA 94158 2330, USA
    Magn Reson Imaging 30:271-82. 2012

Collaborators

Detail Information

Publications17

  1. ncbi Chondrocyte apoptosis: implications for osteochondral allograft transplantation
    Hubert T Kim
    Orthopedic Surgery Section, San Francisco VA Medical Center, 4150 Clement Street 112, San Francisco, CA 94121, USA
    Clin Orthop Relat Res 466:1819-25. 2008
    ..These data suggest that key contributors to the apoptotic process can be manipulated to enhance chondrocyte survival. This knowledge may lead to better surgical outcomes for osteochondral transplantation...
  2. ncbi A mouse model of massive rotator cuff tears
    Xuhui Liu
    San Francisco Veterans Affairs Medical Center, Building 2, Room 639, 4150 Clement Street, San Francisco, CA 94121, USA
    J Bone Joint Surg Am 94:e41. 2012
    ..The goal of this study was to develop a mouse model of muscle atrophy and fatty infiltration after a rotator cuff tear. We also sought to study the role of denervation on muscle atrophy and fatty infiltration after a rotator cuff tear...
  3. ncbi Evaluation of Akt/mTOR activity in muscle atrophy after rotator cuff tears in a rat model
    Xuhui Liu
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, Califronia, USA
    J Orthop Res 30:1440-6. 2012
    ....
  4. ncbi Chondrocyte apoptosis after simulated intraarticular fracture: a comparison of histologic detection methods
    Alexis C Dang
    Department of Orthopaedic Surgery, University of California, 500 Parnassus Avenue, MU320 W, Box 0728, San Francisco, CA 94143, USA
    Clin Orthop Relat Res 467:1877-84. 2009
    ..Using the protocols described in this article, investigators may have additional tools to identify and quantify chondrocytes undergoing programmed cell death after experimental cartilage injury...
  5. ncbi Thermal stress potentiates bupivacaine chondrotoxicity
    Samantha L Piper
    Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California, U S A
    Arthroscopy 28:1246-1254.e1. 2012
    ..The primary objective of this study was to determine whether thermal stress potentiates the chondrotoxic effect of bupivacaine, resulting in decreased articular chondrocyte viability compared with exposure to bupivacaine alone...
  6. ncbi Comparison of ropivacaine and bupivacaine toxicity in human articular chondrocytes
    Samantha L Piper
    J Bone Joint Surg Am 90:986-91. 2008
    ..We compared the in vitro viability of human articular chondrocytes after exposure to bupivacaine, ropivacaine, and saline solution control...
  7. ncbi Admitting service and morbidity and mortality in elderly patients after hip fracture: finding a threshold for medical versus orthopedic admission
    James M Mok
    Department of Orthopaedic Surgery, University of California, San Francisco, 94143 0728, USA
    Am J Orthop (Belle Mead NJ) 39:80-7. 2010
    ..Addition of American Society of Anesthesiologists grade 4 and men 85 or older to existing criteria would increase the percentage of patients with adverse events admitted to a medical service (72% vs 28%; P<.005)...
  8. ncbi Effects of local anesthetics on articular cartilage
    Samantha L Piper
    Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California, USA
    Am J Sports Med 39:2245-53. 2011
    ..Clinically, chondrolysis associated with the use of intra-articular local anesthetic pain pumps has been described by several groups. This has raised concern regarding the clinical use of intra-articular local anesthetics...
  9. ncbi Functional motor recovery after peripheral nerve repair with an aligned nanofiber tubular conduit in a rat model
    Jenny Jin
    San Francisco VA Medical Center, 4150 Clement Street Box 112, San Francisco, CA 94121, USA
    Regen Med 7:799-806. 2012
    ..We examined motor outcomes with the use of longitudinally aligned poly (L-lactide-co-caprolactone) nanofiber conduits for repair of nerve gap injury in a rat model...
  10. ncbi Imaging longitudinal changes in articular cartilage and bone following doxycycline treatment in a rabbit anterior cruciate ligament transection model of osteoarthritis
    James R Pinney
    UC Berkeley UCSF Graduate Program in Bioengineering, San Francisco, CA 94158 2330, USA
    Magn Reson Imaging 30:271-82. 2012
    ....
  11. ncbi Muscle degeneration in rotator cuff tears
    Dominique Laron
    Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA 94158, USA
    J Shoulder Elbow Surg 21:164-74. 2012
    ..Understanding these molecular pathways will help guide further research and treatment options that can aim to alter expression of these pathways and improve outcomes after surgical repair of massive rotator cuff tears...
  12. ncbi A peek into the possible future of management of articular cartilage injuries: gene therapy and scaffolds for cartilage repair
    Hubert T Kim
    Department of Orthopaedic Surgery, University of California, San Francisco, CA 94143-0728, USA
    J Orthop Sports Phys Ther 36:765-73. 2006
    ..The resulting "neo-cartilage implant" matures within the bioreactor, and can then be used to fill cartilage defects...
  13. ncbi Chondrocyte apoptosis induced by hydrogen peroxide requires caspase activation but not mitochondrial pore transition
    Marvin Y Lo
    Department of Orthopaedic Surgery, University of California, San Francisco, CA, USA
    J Orthop Res 22:1120-5. 2004
    ..These results show that H2O2 triggers chondrocyte apoptosis through caspase activation, independent of mitochondrial membrane permeability transition...
  14. ncbi Comparison of chondrocyte apoptosis in vivo and in vitro following acute osteochondral injury
    John G Costouros
    Department of Orthopaedic Surgery, University of California, San Francisco, CA 94143, USA
    J Orthop Res 22:678-83. 2004
    ....
  15. ncbi Chondrocyte apoptosis induced by collagen degradation: inhibition by caspase inhibitors and IGF-1
    Marvin Y Lo
    Department of Orthopaedic Surgery, University of California, San Francisco, CA, USA
    J Orthop Res 22:140-4. 2004
    ..Furthermore, these findings suggest that multiple pathways involving both the initiation and execution of programmed cell death are potential targets for chondrocyte apoptosis inhibition therapy...
  16. ncbi Enhancing osteochondral allograft viability: effects of storage media composition
    Margie S Teng
    Stanford University School of Medicine, Stanford, CA, USA
    Clin Orthop Relat Res 466:1804-9. 2008
    ..These results confirm the hypotheses that media composition greatly influences chondrocyte viability during cold storage and that insulin growth factor-1 and ZVAD improve the storage properties of DMEM...
  17. ncbi Preventing chondrocyte programmed cell death caused by iatrogenic injury
    John G Costouros
    Department of Orthopaedic Surgery, University of California Medical Center, San Francisco, CA 95119, United States
    Knee 14:107-11. 2007
    ..1+/-2.4%; controls=26.5+/-3.6%; (p=0.0013)]. These results provide proof of concept for the use of PCD inhibitors to enhance the results of cartilage repair surgeries...