CHELSEA M KIDWELL

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Access to intra-arterial therapies for acute ischemic stroke: an analysis of the US population
    Shuichi Suzuki
    Department of Radiological Sciences, UCLA School of Medicine, 10833 Le Conte Ave, room B2 188 CHS, Los Angeles, CA 90095 1721, USA
    AJNR Am J Neuroradiol 25:1802-6. 2004
  2. doi request reprint Acute stroke imaging research roadmap
    Max Wintermark
    University of California, San Francisco, Department of Radiology, Neuroradiology Section, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Stroke 39:1621-8. 2008
  3. ncbi request reprint Design and retrospective analysis of the Los Angeles Prehospital Stroke Screen (LAPSS)
    C S Kidwell
    UCLA Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, California 90095, USA
    Prehosp Emerg Care 2:267-73. 1998
  4. ncbi request reprint Evolving paradigms in neuroimaging of the ischemic penumbra
    Chelsea S Kidwell
    UCLA Stroke Center, 710 Westwood Plaza, UCLA Medical Center, Los Angeles, CA 9009, USA5
    Stroke 35:2662-5. 2004
  5. ncbi request reprint Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging
    Chelsea S Kidwell
    University of California at Los Angeles Stroke Center, Los Angeles, CA 90095, USA
    Stroke 34:2729-35. 2003
  6. ncbi request reprint Establishment of primary stroke centers: a survey of physician attitudes and hospital resources
    C S Kidwell
    Department of Neurology and UCLA Stroke Center, UCLA Medical Center, Los Angeles, CA 90095, USA
    Neurology 60:1452-6. 2003
  7. ncbi request reprint Comparison of MRI and CT for detection of acute intracerebral hemorrhage
    Chelsea S Kidwell
    UCLA Stroke Center, Los Angeles, Calif, USA
    JAMA 292:1823-30. 2004
  8. ncbi request reprint Late secondary ischemic injury in patients receiving intraarterial thrombolysis
    Chelsea S Kidwell
    Stroke Center, UCLA Medical Center, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Ann Neurol 52:698-703. 2002
  9. ncbi request reprint Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis
    Chelsea S Kidwell
    UCLA Stroke Center, UCLA Medical Center, Los Angeles, Calif 90095, USA
    Stroke 33:717-24. 2002
  10. ncbi request reprint Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application
    Chelsea S Kidwell
    UCLA Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, CA 90095, USA
    Stroke 33:95-8. 2002

Research Grants

  1. MR ASSESSMENT OF MAGNESIUM IN ACUTE STROKE
    Chelsea Kidwell; Fiscal Year: 2003

Detail Information

Publications47

  1. ncbi request reprint Access to intra-arterial therapies for acute ischemic stroke: an analysis of the US population
    Shuichi Suzuki
    Department of Radiological Sciences, UCLA School of Medicine, 10833 Le Conte Ave, room B2 188 CHS, Los Angeles, CA 90095 1721, USA
    AJNR Am J Neuroradiol 25:1802-6. 2004
    ..The purpose of this study was to identify the percentage of the US population with potential access to interventional neuroradiologic expertise within 6 hours of the onset of stroke symptoms...
  2. doi request reprint Acute stroke imaging research roadmap
    Max Wintermark
    University of California, San Francisco, Department of Radiology, Neuroradiology Section, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Stroke 39:1621-8. 2008
    ..The present article summarizes these recommendations and examines practical steps to achieve them...
  3. ncbi request reprint Design and retrospective analysis of the Los Angeles Prehospital Stroke Screen (LAPSS)
    C S Kidwell
    UCLA Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, California 90095, USA
    Prehosp Emerg Care 2:267-73. 1998
    ..Further, the study evaluated the potential time savings that could be achieved by paramedic administration of neuroprotective agents in the field...
  4. ncbi request reprint Evolving paradigms in neuroimaging of the ischemic penumbra
    Chelsea S Kidwell
    UCLA Stroke Center, 710 Westwood Plaza, UCLA Medical Center, Los Angeles, CA 9009, USA5
    Stroke 35:2662-5. 2004
    ....
  5. ncbi request reprint Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging
    Chelsea S Kidwell
    University of California at Los Angeles Stroke Center, Los Angeles, CA 90095, USA
    Stroke 34:2729-35. 2003
    ..Recent advances in magnetic resonance imaging of the ischemic penumbra have been driven by serial MRI studies characterizing the natural evolution of cerebral infarction as well as the brain's response to reperfusion...
  6. ncbi request reprint Establishment of primary stroke centers: a survey of physician attitudes and hospital resources
    C S Kidwell
    Department of Neurology and UCLA Stroke Center, UCLA Medical Center, Los Angeles, CA 90095, USA
    Neurology 60:1452-6. 2003
    ....
  7. ncbi request reprint Comparison of MRI and CT for detection of acute intracerebral hemorrhage
    Chelsea S Kidwell
    UCLA Stroke Center, Los Angeles, Calif, USA
    JAMA 292:1823-30. 2004
    ..However, the accuracy of MRI relative to CT for the detection of hyperacute intracerebral hemorrhage has not been demonstrated...
  8. ncbi request reprint Late secondary ischemic injury in patients receiving intraarterial thrombolysis
    Chelsea S Kidwell
    Stroke Center, UCLA Medical Center, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Ann Neurol 52:698-703. 2002
    ..In the future, late secondary tissue injury may become an important therapeutic target for postreperfusion neuroprotective therapies, with treatment efficacy monitored by serial diffusion magnetic resonance imaging...
  9. ncbi request reprint Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis
    Chelsea S Kidwell
    UCLA Stroke Center, UCLA Medical Center, Los Angeles, Calif 90095, USA
    Stroke 33:717-24. 2002
    ..Hemorrhagic transformation (HT) is a major complication of intra-arterial (IA) thrombolytic therapy. Identifying significant predictors of hemorrhage after thrombolysis would be useful in guiding patient selection for IA treatment...
  10. ncbi request reprint Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application
    Chelsea S Kidwell
    UCLA Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, CA 90095, USA
    Stroke 33:95-8. 2002
    ....
  11. ncbi request reprint Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans
    C S Kidwell
    UCLA Stroke Center, UCLA Medical Center, Los Angeles, CA 90095, USA
    Neurology 57:2015-21. 2001
    ..Animal and human studies have demonstrated that postischemic hyperperfusion may occur both early and late timepoints following acute cerebral ischemia...
  12. ncbi request reprint Diffusion MRI in patients with transient ischemic attacks
    C S Kidwell
    University of California at Los Angeles, CA, USA
    Stroke 30:1174-80. 1999
    ..Diffusion MRI has established value in patients with ischemic stroke but has not been systematically investigated in patients with transient ischemic attack (TIA)...
  13. ncbi request reprint Identifying stroke in the field. Prospective validation of the Los Angeles prehospital stroke screen (LAPSS)
    C S Kidwell
    University of California at Los Angeles Stroke Center, Department of Neurology, Los Angeles, CA 90095, USA
    Stroke 31:71-6. 2000
    ..We performed a prospective, in-the-field validation study of the LAPSS...
  14. ncbi request reprint Advances in neuroimaging of acute stroke
    C S Kidwell
    University of California, Los Angeles, Stroke Center, 710 Westwood Plaza, UCLA Medical Center, Los Angeles, CA 90095, USA
    Curr Atheroscler Rep 2:126-35. 2000
    ....
  15. ncbi request reprint Trends in acute ischemic stroke trials through the 20th century
    C S Kidwell
    University of California at Los Angeles UCLA Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, CA 90095, USA
    Stroke 32:1349-59. 2001
    ..The objective of this study was to quantitatively characterize developments in clinical trial methodology over time in the field of acute ischemic stroke...
  16. ncbi request reprint Diffusion-perfusion MR evaluation of perihematomal injury in hyperacute intracerebral hemorrhage
    C S Kidwell
    Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, CA 90095, USA
    Neurology 57:1611-7. 2001
    ..Diffusion-perfusion MRI provides a novel means of assessing injury in perihematomal regions in patients with ICH...
  17. ncbi request reprint Transcranial Doppler pulsatility indices as a measure of diffuse small-vessel disease
    C S Kidwell
    Stroke Center, Department of Neurology, 710 Westwood Plaza, UCLA Medical Center, Los Angeles, CA 90095, USA
    J Neuroimaging 11:229-35. 2001
    ..Elevation in pulsatility indices (PIs) as measured by transcranial Doppler (TCD) have been postulated to reflect downstream increased vascular resistance caused by small-vessel ischemic disease...
  18. ncbi request reprint Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue
    Ludy C Shih
    UCLA Stroke Center, UCLA Medical Center, Los Angeles, Calif, USA
    Stroke 34:1425-30. 2003
    ..Pretreatment perfusion MRI offers promise as a means to differentiate core from penumbral tissues...
  19. ncbi request reprint Use of multimodal MRI and novel endovascular therapies in a patient ineligible for intravenous tissue plasminogen activator
    Shuichi Suzuki
    Department of Radiology, UCLA Medical Center, Los Angeles, California, USA
    Stroke 36:e77-9. 2005
    ..We report a patient who twice benefited from this management approach, in the setting of hemorrhagic risk following successive ischemic strokes...
  20. ncbi request reprint Validation of computed tomographic middle cerebral artery "dot"sign: an angiographic correlation study
    Megan C Leary
    Department of Neurology, Division of Stroke and Cerebrovascular Disease, Palmer 125, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, Mass 02215, USA
    Stroke 34:2636-40. 2003
    ..The MCA dot sign has not been validated previously against the gold standard of conventional cerebral angiography...
  21. ncbi request reprint Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial
    Wade S Smith
    Department of Neurology, University of California, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 36:1432-8. 2005
    ..An alternative strategy for opening intracranial vessels during stroke is mechanical embolectomy, especially for patients ineligible for intravenous tPA...
  22. doi request reprint Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke
    Chelsea S Kidwell
    Department of Neurology, Georgetown University, Washington, DC 20010, USA
    Cerebrovasc Dis 25:338-43. 2008
    ..Early barrier opening caused by focal cerebral ischemia in human stroke can be assessed by the presence of gadolinium enhancement of cerebrospinal fluid, termed 'Hyperintense Acute Injury Marker' (HARM)...
  23. pmc Genomic profiles of damage and protection in human intracerebral hemorrhage
    S Thomas Carmichael
    Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    J Cereb Blood Flow Metab 28:1860-75. 2008
    ..These inflammatory and anti-inflammatory networks interact at several key points in neutrophil signaling, apoptotic cell death, and protease responses, and indicate that secondary damage in ICH activates opposing molecular systems...
  24. ncbi request reprint Treatment adherence rates one year after initiation of a systematic hospital-based stroke prevention program
    Bruce Ovbiagele
    Stroke Center and Department of Neurology, UCLA Medical Center, Los Angeles, Calif 90095, USA
    Cerebrovasc Dis 20:280-2. 2005
  25. ncbi request reprint In-hospital initiation of secondary stroke prevention therapies yields high rates of adherence at follow-up
    Bruce Ovbiagele
    Stroke Center and Department of Neurology, University of California at Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Stroke 35:2879-83. 2004
    ..The objective of this study was to determine if the high utilization rates previously demonstrated at hospital discharge were maintained at 90 days after discharge...
  26. doi request reprint Image-guided endoscopic evacuation of spontaneous intracerebral hemorrhage
    Chad M Miller
    Division of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles 90095, USA
    Surg Neurol 69:441-6; discussion 446. 2008
    ..Image-guided stereotactic endoscopic hematoma evacuation is a promising minimally invasive approach designed to limit operative injury and maximize hematoma removal...
  27. ncbi request reprint Expanding indications for statins in cerebral ischemia: a quantitative study
    Bruce Ovbiagele
    Stroke Center and Department of Neurology, UCLA Medical Center, University of California at Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Arch Neurol 62:67-72. 2005
    ....
  28. ncbi request reprint Epidemiological impact in the United States of a tissue-based definition of transient ischemic attack
    Bruce Ovbiagele
    UCLA Stroke Center, Department of Neurology, UCLA Medical Center, 90095, USA
    Stroke 34:919-24. 2003
    ..The objective of this study was to characterize the epidemiological impact of adopting a tissue-based definition of TIA...
  29. ncbi request reprint Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies
    Jill L Ostrem
    Department of Neurology, UCLA Medical Center, USA
    Stroke 35:e30-4. 2004
    ..Diffusion-perfusion MRI in patients with anterior circulation occlusions has demonstrated salvage of threatened tissue after thrombolytic therapy. Similar studies have not been reported with posterior circulation occlusions...
  30. ncbi request reprint Neuroprotective agents for the treatment of acute ischemic stroke
    Bruce Ovbiagele
    Stroke Center and Department of Neurology, University of California at Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Curr Neurol Neurosci Rep 3:9-20. 2003
    ....
  31. pmc Dispatcher recognition of stroke using the National Academy Medical Priority Dispatch System
    Brian H Buck
    University of California at Los Angeles Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, CA, USA
    Stroke 40:2027-30. 2009
    ..1 of the National Academy Medical Priority Dispatch System)...
  32. ncbi request reprint The Los Angeles Motor Scale (LAMS): a new measure to characterize stroke severity in the field
    Jennifer N Llanes
    UCLA Stroke Center, 90095, USA
    Prehosp Emerg Care 8:46-50. 2004
    ..To develop and retrospectively analyze an instrument that rapidly characterizes pretreatment stroke severity for use in prehospital acute stroke clinical trials...
  33. ncbi request reprint Advanced MR imaging of acute stroke: the University of California at Los Angeles endovascular therapy experience
    David S Liebeskind
    University of California at Los Angeles Stroke Center, UCLA Medical Center, Los Angeles, CA 90095, USA
    Neuroimaging Clin N Am 15:455-66, xiii. 2005
    ..The ensuing review emphasizes salient aspects of these neuroimaging studies, addressing numerous facets of acute stroke pathophysiology...
  34. pmc Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials
    Jeffrey L Saver
    Department of Neurology, Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Stroke 40:2594-600. 2009
    ..a. thrombolysis or devices may be acceptable. Statistical considerations and definitions of successful recanalization/reperfusion are suggested for these trials...
  35. pmc Development and validation of a simple conversion model for comparison of intracerebral hemorrhage volumes measured on CT and gradient recalled echo MRI
    Richard E Burgess
    Department of Neurology, Georgetown University Hospital, 3800 Reservoir Road, NW, 7th Floor PHC Bldg, Washington, DC 20007, USA
    Stroke 39:2017-20. 2008
    ..However, because of the differences in the signal parameter being detected, apparent hemorrhage size is expected to vary by imaging modality, with GRE providing larger volumes attributable to susceptibility effects...
  36. pmc Update of the stroke therapy academic industry roundtable preclinical recommendations
    Marc Fisher
    Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Stroke 40:2244-50. 2009
    ..Although the recommendations cannot be validated until effective therapies based on them emerge from clinical trials, it is hoped that adherence to them might enhance the chances for success...
  37. pmc Acute stroke imaging research roadmap
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 29:e23-30. 2008
    ..The present article summarizes these recommendations and examines practical steps to achieve them...
  38. ncbi request reprint Evidence of publication bias in reporting acute stroke clinical trials
    David S Liebeskind
    Comprehensive Stroke Center and Department of Neurology, University of Pennsylvania, Philadelphia, USA
    Neurology 67:973-9. 2006
    ..To ascertain the extent of publication bias in the reporting of acute stroke clinical trials...
  39. ncbi request reprint Acute ischemic cerebrovascular syndrome: diagnostic criteria
    Chelsea S Kidwell
    University of California at Los Angeles Stroke Center and Department of Neurology, University of California at Los Angeles Medical Center, USA
    Stroke 34:2995-8. 2003
    ..Diagnostic certainty of the ischemic pathology based on supportive or refuting laboratory or radiological evidence has been of secondary importance...
  40. ncbi request reprint Withdrawal of warfarin prior to a surgical procedure: time to follow the guidelines?
    Sergey E Akopov
    Division of Neurology, Cedars Sinai Medical Center Los Angeles, CA 90048, USA
    Cerebrovasc Dis 19:337-42. 2005
    ..The purpose of this study was to determine frequency of cardioembolic cerebral infarction during periprocedural warfarin withdrawal...
  41. ncbi request reprint Enhancing the development and approval of acute stroke therapies: Stroke Therapy Academic Industry roundtable
    Marc Fisher
    UMass Memorial Healthcare Center, 119 Belmont St, Worcester, MA 01605, USA
    Stroke 36:1808-13. 2005
    ..A fourth (STAIR-IV) was held to discuss relevant issues related to acute stroke drug development and regulatory approval...
  42. ncbi request reprint Predictors of apparent diffusion coefficient normalization in stroke patients
    Jens Fiehler
    Department of Neuroradiology, University Hospital Eppendorf, University of Hamburg, Hamburg, Germany
    Stroke 35:514-9. 2004
    ..We sought to describe the frequency of normalization of apparent diffusion coefficient (ADC) values that are decreased in hyperacute stroke and to identify characteristics of tissue demonstrating normalization...
  43. ncbi request reprint Imaging of the brain and cerebral vasculature in patients with suspected stroke: advantages and disadvantages of CT and MRI
    Chelsea S Kidwell
    WHC Stroke Center, 110 Irving Street NW, East Building Room 6126, Washington, DC 20010, USA
    Curr Neurol Neurosci Rep 6:9-16. 2006
    ..The multimodal combinations of advanced imaging techniques, particularly in the realm of CT and MRI, have emerged as the most promising noninvasive approaches to acute stroke evaluation...
  44. ncbi request reprint Beyond tissue plasminogen activator: mechanical intervention in acute stroke
    Megan C Leary
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Ann Emerg Med 41:838-46. 2003
    ..The purpose of this review is to provide the emergency medicine community with an understanding of these promising and emerging approaches to acute stroke therapy...
  45. ncbi request reprint MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia
    Y Pierre Gobin
    Division of Interventional Neuroradiology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10021, USA
    Stroke 35:2848-54. 2004
    ..To report the result of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) 1 study, a phase 1 trial to evaluate the safety and efficacy of mechanical embolectomy in the cerebral vasculature...
  46. ncbi request reprint The redefinition of TIA: the uses and limitations of DWI in acute ischemic cerebrovascular syndromes
    Steven Warach
    Neurology 62:359-60. 2004
  47. pmc Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison
    Julio A Chalela
    Medical University of South Carolina, Charleston, SC, USA
    Lancet 369:293-8. 2007
    ..We aimed to prospectively compare CT and MRI for emergency diagnosis of acute stroke...

Research Grants1

  1. MR ASSESSMENT OF MAGNESIUM IN ACUTE STROKE
    Chelsea Kidwell; Fiscal Year: 2003
    ..abstract_text> ..