Brian A Kidd
Affiliation: University of Washington
- Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelinationBrian A Kidd
Department of Medicine, Division of Immunology and Rheumatology, CCSR 4135, 269 Campus Dr, Stanford University School of Medicine, Stanford, CA, USA
Arthritis Res Ther 10:R119. 2008..Citrullination is the post-translational conversion of arginine to citrulline by peptidyl arginine deiminase, and increased citrullination of proteins is observed in the joint tissue in RA and in brain tissue in multiple sclerosis (MS)...
- Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokinesWolfgang Hueber
Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, and Palo Alto VA Health Care System, MC 154R, 3801 Miranda Avenue, Palo Alto, CA 94304, USA
Ann Rheum Dis 66:712-9. 2007..To identify peripheral blood autoantibody and cytokine profiles that characterise clinically relevant subgroups of patients with early rheumatoid arthritis using arthritis antigen microarrays and a multiplex cytokine assay...
- Tolerizing DNA vaccines for autoimmune arthritisPeggy P Ho
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
Autoimmunity 39:675-82. 2006....
- Treatment of autoimmune neuroinflammation with a synthetic tryptophan metaboliteMichael Platten
Department of Neurology and Neurological Sciences, Beckman Center for Molecular Medicine, Stanford University, Stanford, CA 94305, USA
Science 310:850-5. 2005..Trp catabolites and their derivatives offer a new strategy for treating T(H)1-mediated autoimmune diseases such as MS...
- A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune diseasePeggy P Ho
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, CA 94305, USA
J Immunol 175:6226-34. 2005..These results demonstrate that suppressive GpG-ODN is a simple and highly effective novel therapeutic adjuvant that will boost the efficacy of Ag-specific tolerizing DNA vaccines used for treating Th1-mediated autoimmune diseases...
- Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing-remitting multiple sclerosisKeith Van Haren
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA, USA
Mult Scler 19:1726-33. 2013..Because autoantibodies may contribute to the pathogenesis of both diseases, we sought to identify autoantibody biomarkers that are capable of distinguishing them...
- Antigen microarray profiling of autoantibodies in rheumatoid arthritisWolfgang Hueber
Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
Arthritis Rheum 52:2645-55. 2005....
- Virus-specific CD4(+) memory-phenotype T cells are abundant in unexposed adultsLaura F Su
Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94304, USA
Immunity 38:373-83. 2013..Thus, the presence of these memory-phenotype T cells has significant implications for immunity to novel pathogens, child and adult health, and the influence of pathogen-rich versus hygienic environments...
- Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitisPaulo Fontoura
Department of Neurology and Neurological Sciences, School of Medicine, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA
J Immunol 173:6981-92. 2004..These results indicate that some T cell and B cell immune responses to Nogo-66 are associated with suppression of ongoing EAE, whereas other Nogo-66 epitopes can be encephalitogenic...
- γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 responseXun Zeng
Department of Microbiology and Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA
Immunity 37:524-34. 2012..These results underscore the adaptability of lymphocyte antigen receptors and suggest an antigen-driven rapid response in protective immunity prior to the maturation of classical adaptive immunity...