Research Topics
Genomes and GenesSpecies | Muhammad G KibriyaSummaryAffiliation: University of Chicago Country: USA Publications
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Publications
A genome-wide DNA methylation study in colorectal carcinomaMuhammad G Kibriya
Department of Health Studies, The University of Chicago, Chicago, IL 60637, USA
BMC Med Genomics 4:50. 2011..We performed a genome-wide scan of 27,578 CpG loci covering 14,475 genes to identify differentially methylated loci (DML) in colorectal carcinoma (CRC)...
A pilot genome-wide association study of early-onset breast cancerMuhammad G Kibriya
Department of Health Studies, The University of Chicago, 5841 S Maryland Avenue, MC 2007, Chicago, IL 60637, USA
Breast Cancer Res Treat 114:463-77. 2009..Nevertheless, without systematic replication, findings from this pilot study, especially the associations of breast cancer in relation to specific SNPs, should be interpreted with great caution...- Changes in gene expression profiles in response to selenium supplementation among individuals with arsenic-induced pre-malignant skin lesionsMuhammad G Kibriya
Department of Epidemiology, Mailman School of Public Health, Columbia University, USA
Toxicol Lett 169:162-76. 2007..Additionally, this study suggests that long-term selenium supplementation may revert some of the gene expression changes presumably induced by chronic As exposure in individuals with pre-malignant skin lesions... - Interpretation of genome-wide infinium methylation data from ligated DNA in formalin-fixed, paraffin-embedded paired tumor and normal tissueFarzana Jasmine
Department of Health Studies, The University of Chicago, Chicago, IL 60637, USA
BMC Res Notes 5:117. 2012..We report locus-specific correlation and concordance of tumor-specific differentially methylated loci (DML), both of which were not previously assessed... 
Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in BangladeshHabibul Ahsan
Departments of Epidemiology, Columbia University, USA
Cancer Epidemiol Biomarkers Prev 16:1270-8. 2007....- A genome-wide study of cytogenetic changes in colorectal cancer using SNP microarrays: opportunities for future personalized treatmentFarzana Jasmine
Department of Health Studies, The University of Chicago, Chicago, Illinois, United States of America
PLoS ONE 7:e31968. 2012..Our study shows the application of high density SNP arrays for cytogenetic study in CRC and its potential utility for personalized treatment... - Effect of selenium and vitamin e supplementation on plasma protein carbonyl levels in patients with arsenic-related skin lesionsJulie Mahata
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
Nutr Cancer 60:55-60. 2008.... - Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in BangladeshBrandon L Pierce
Department of Health Studies, The University of Chicago, Chicago, Illinois, United States of America
PLoS Genet 8:e1002522. 2012..These results have potential translational implications for the prevention and treatment of arsenic-associated toxicities worldwide... - Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi populationMaria Argos
Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 15:1367-75. 2006..Genes identified from this analysis may provide insights into the underlying processes of arsenic-induced disease and represent potential targets for chemoprevention studies to reduce arsenic-induced skin cancer in this population... - A CYP19 (aromatase) polymorphism is associated with increased premenopausal breast cancer riskKathryn E Talbott
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA
Breast Cancer Res Treat 111:481-7. 2008..The finding supports the potential role of variation in estrogen biosynthesis genes in premenopausal breast cancer risk... - Genomewide scan for loss of heterozygosity and chromosomal amplification in breast carcinoma using single-nucleotide polymorphism arraysMaria Argos
Department of Health Studies, University of Chicago, 5841 S Maryland Avenue, MC 2007, Chicago, IL 60637, USA
Cancer Genet Cytogenet 182:69-74. 2008..The present study demonstrates a feasible methodological approach for the assessment of LOH and copy number changes... - A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in BangladeshWendy J Verret
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
J Occup Environ Med 47:1026-35. 2005..CONCLUSIONS: Supplementation with vitamin E and selenium, either alone or in combination, slightly improved skin lesion status, although the improvement was not statistically significant... - Whole-genome amplification enables accurate genotyping for microarray-based high-density single nucleotide polymorphism arrayFarzana Jasmine
Department of Health Studies, The University of Chicago, 5841 South Maryland Avenue, MC 2007, Chicago, IL 60637, USA
Cancer Epidemiol Biomarkers Prev 17:3499-508. 2008..29%. In conclusion, our study confirms that high-density oligonucleotide array-based genotyping can yield reproducible data and MDA-WGA DNA products can be effectively used for genome-wide SNP genotyping analysis... - Variants in estrogen metabolism and biosynthesis genes and urinary estrogen metabolites in women with a family history of breast cancerHeather Greenlee
Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, 7th Floor, New York, NY 10032, USA
Breast Cancer Res Treat 102:111-7. 2007.... - Analyses and interpretation of whole-genome gene expression from formalin-fixed paraffin-embedded tissue: an illustration with breast cancer tissuesMuhammad G Kibriya
Department of Health Studies, The University of Chicago, 5841 S, Maryland Avenue, MC 2007, Chicago, IL 60637, USA
BMC Genomics 11:622. 2010..We used a whole genome DASL assay (addressing 18,391 genes) on a total of 72 samples from paired breast tumor and surrounding healthy tissues from both FF and FFPE samples... - A family-based genetic association study of variants in estrogen-metabolism genes COMT and CYP1B1 and breast cancer riskHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Breast Cancer Res Treat 85:121-31. 2004.... - Susceptibility to arsenic-induced hyperkeratosis and oxidative stress genes myeloperoxidase and catalaseHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columfbia University, Room 720G, 722 West 168th Street, New York, NY 10032, USA
Cancer Lett 201:57-65. 2003..Our findings, although based on small numbers, suggest that the oxidative stress genes MPO and CAT may influence the risk of arsenic-induced premalignant hyperkeratotic skin lesions... - Environmental mutagens induced transversions but not transitions in regulatory region of mitochondrial DNAMichael A Partridge
Center for Radiological Research, Columbia University, New York, NY 10032, USA
J Toxicol Environ Health A 72:301-4. 2009..Data suggest that only a change in the number of rare transversions would be indicative of an increase in point mutations in mtDNA after exposure to mutagens... - Genome-wide DNA methylation profiles in hepatocellular carcinomaJing Shen
Department of Environmental Health Sciences, Columbia University, New York, NY 10032, USA
Hepatology 55:1799-808. 2012..CONCLUSION: The panel of methylated genes indentified in the current study will be further tested in a large cohort of prospectively collected samples to determine their utility as early biomarkers of HCC... - Association between arsenic exposure from drinking water and plasma levels of soluble cell adhesion moleculesYu Chen
Departments of Environmental Medicine and Medicine, and New York University Cancer Institute, New York University School of Medicine, New York, New York 10016, USA
Environ Health Perspect 115:1415-20. 2007..Epidemiologic studies of cardiovascular disease risk factors and appropriate biomarkers in populations exposed to a wide range of arsenic levels are a public health research priority...