Affiliation: University of California
- Stress-related modulation of inflammation in experimental models of bowel disease and post-infectious irritable bowel syndrome: role of corticotropin-releasing factor receptorsCornelia Kiank
David Geffen School of Medicine at UCLA, CURE Digestive Diseases Research Center Animal Core, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
Brain Behav Immun 24:41-8. 2010....
- Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humansCornelia Kiank
Department of Immunology, DFG graduate school GK840, Ernst Moritz Arndt University, Greifswald, Germany
PLoS ONE 5:e11825. 2010..Since patients showed Trp catabolism already prior to surgery, IDO is also a possible target enzyme for humans modulating immune homeostasis and mood...
- Mild postnatal separation stress reduces repeated stress-induced immunosuppression in adult BALB/c miceCornelia Kiank
Department of Immunology, DFG Graduiertenkolleg 840, Ernst Moritz Arndt University Greifswald, Greifswald, Germany
Neuro Endocrinol Lett 30:761-8. 2009..In this study, we investigated consequences of mild postnatal stress exposure on the stress coping style of adult BALB/c mice...
- Pneumonia as a long-term consequence of chronic psychological stress in BALB/c miceCornelia Kiank
Department of Immunology, Ernst Moritz Arndt University Greifswald, Sauerbruchstrasse, D 17487 Greifswald, Germany
Brain Behav Immun 22:1173-7. 2008..Thus, a deficient antibacterial response to translocated commensals in chronically stressed animals can contribute to long-lasting pneumonia...
- Altered hepatic mRNA expression of immune response and apoptosis-associated genes after acute and chronic psychological stress in miceMaren Depke
Interfaculty Institute of Genetics and Functional Genomics, Ernst Moritz Arndt University Greifswald, Germany
Mol Immunol 46:3018-28. 2009..However, immune suppression will only manifest in repeatedly stressed mice which additionally show induction of protective and liver regenerative genes to prevent further hepatocyte damage...
- Hypermetabolic syndrome as a consequence of repeated psychological stress in miceMaren Depke
Ernst Moritz Arndt University, Interfaculty Institute of Genetics and Functional Genomics, 17487 Greifswald, Germany
Endocrinology 149:2714-23. 2008..Under such circumstances stress may further reduce the ability to cope with new stressors such as infection or cancer...
- Different stress-related phenotypes of BALB/c mice from in-house or vendor: alterations of the sympathetic and HPA axis responsivenessJakob Olfe
Department of Immunology, DFG graduate school GK840, Ernst Moritz Arndt University Greifswald, Germany
BMC Physiol 10:2. 2010..Here, we investigated if female BALB/c mice derived from in-house breeding and BALB/c mice from a vendor which were shipped during their juvenile life differ in their HPA axis activity and stress responsiveness in adulthood...
- Seasonal variations in inflammatory responses to sepsis and stress in miceCornelia Kiank
Departments of Immunology, University of Greifswald, Greifswald, Germany
Crit Care Med 35:2352-8. 2007..In this study, we analyzed seasonal variations of immunoreactivity using a model of septic shock and a model of immunosuppression induced by chronic stress in mice...
- A role for corticotropin-releasing factor in functional gastrointestinal disordersYVETTE TACHE
Center for Ulcer Research and Education CURE Digestive Diseases Research Center, Building 115, Room 117, VA Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
Curr Gastroenterol Rep 11:270-7. 2009..Yet to be ascertained is whether CRF1 receptor antagonists hold promise as a new therapy in IBS treatment...
- Stress-induced immune conditioning affects the course of experimental peritonitisCornelia Kiank
Department of Immunology, Ernst Moritz Arndt University, Greifswald, Germany
Shock 27:305-11. 2007..It ameliorates lethal shock responses but reduces the capacity to eradicate bacterial infection during mild peritonitis...