Affiliation: University of Pittsburgh
- Decision tree modeling predicts effects of inhibiting contractility signaling on cell motilitySourabh Kharait
Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA
BMC Syst Biol 1:9. 2007....
- Protein kinase Cdelta signaling downstream of the EGF receptor mediates migration and invasiveness of prostate cancer cellsSourabh Kharait
Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh VAMC, Pittsburgh, PA 15261, USA
Biochem Biophys Res Commun 343:848-56. 2006..Thus, we conclude that PKCdelta inhibition can limit migration and invasion of prostate cancer cells...
- DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signalingAsmaa Mamoune
Department of Pathology, University of Pittsburgh, PA 15261, USA
Exp Cell Res 299:91-100. 2004..Herein, a number of key molecules whose expression levels are interrelated, including both EGFR and uPAR, are required but none are sufficient in the absence of other keys molecules in promoting tumor progression...