Research Topics
| Mandana KhaliliSummaryAffiliation: University of California Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Impact of insulin resistance on HCV treatment response and impact of HCV treatment on insulin sensitivity using direct measurements of insulin actionDanielle Brandman
Department of Medicine, University of California San Francisco, San Francisco, California, USA
Diabetes Care 35:1090-4. 2012....- Formal patient education improves patient knowledge of hepatitis C in vulnerable populationsMiranda Surjadi
Department of Medicine, San Francisco General Hospital, University of California San Francisco, 1001 Potrero Ave, NH 3D, San Francisco, CA 94110, USA
Dig Dis Sci 56:213-9. 2011..Vulnerable populations including IDUs are disproportionally affected by HCV. Effective HCV education can potentially reduce disparity in HCV prevalence and its outcome in this population... - Hepatitis B and hepatocellular carcinoma screening among Asian Americans: survey of safety net healthcare providersMandana Khalili
Department of Medicine, University of California San Francisco, San Francisco General Hospital, 1001 Potrero Ave, NH 3D, San Francisco, CA 94110, USA
Dig Dis Sci 56:1516-23. 2011..Physician patterns of screening for hepatitis B (HBV) and hepatocellular carcinoma (HCC) among Asian Americans are not well described... 
Applicability, tolerability and efficacy of preemptive antiviral therapy in hepatitis C-infected patients undergoing liver transplantationAmandeep K Shergill
Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Am J Transplant 5:118-24. 2005..Future studies should focus on alternative dosing schedules with more aggressive use of adjuvant therapies, including GFs...- Methods for quantifying insulin resistance in human immunodeficiency virus-positive patientsJames W Chu
Department of Medicine, Stanford University School of Medicine, CA, USA
Metabolism 52:858-61. 2003..43 to 0.61), thereby possessing limited ability to predict SSPG variability (r2=0.18 to 0.37). In conclusion, indirect measures of IMGU need to be applied with caution when evaluating insulin action in HIV-infected patients... - Management of hepatitis C-infected liver transplant recipients at large North American centres: changes in recent yearsMandana Khalili
Department of Medicine, University of California, San Francisco, CA 94110, USA
Clin Transplant 20:1-9. 2006..We conclude that there is considerable variability in the management of HCV among transplant programs and over time... - Pegylated interferon alpha-2a with or without ribavirin in HCV/HIV coinfection: partially blinded, randomized multicenter trialMandana Khalili
University of California, San Francisco, San Francisco, California, USA
Dig Dis Sci 50:1148-55. 2005..PegIFNalpha-2a was therefore at least as effective as standard interferon and ribavirin combination therapy and was well tolerated, without a negative impact on HIV parameters... - Relative effects of insulin resistance and protease inhibitor treatment on lipid and lipoprotein metabolism in HIV-infected patientsGeorge Beatty
Department of Medicine, University of California San Francisco at San Francisco General Hospital, San Francisco, California 94110, USA
HIV Clin Trials 5:383-91. 2004..The relationship between insulin resistance, dyslipidemia, HIV infection, and antiretroviral therapy remains unclear, and the atherogenic nature of lipid and lipoprotein profiles in HIV-infected patients has not been fully characterized... - Treatment of the hepatitis C virus in patients coinfected with HIVMandana Khalili
University of California, San Francisco, San Francisco General Hospital, 1001 Potrero Avenue, NH 3D, San Francisco, CA 94110, USA
Gastroenterol Clin North Am 33:479-96, vii-viii. 2004..Moreover, interactions between HCV and HIV antiviral medications may occur and potentially affect treatment efficacy. Thus, the decision to undertake HCV treatment must be individualized... - New onset diabetes mellitus after liver transplantation: the critical role of hepatitis C infectionMandana Khalili
Department of Medicine, University of California San Francisco, San Francisco, CA 94110, USA
Liver Transpl 10:349-55. 2004..However, among those developing de novo persistent diabetes, HCV is one of the most important risk factors. This adds further support to the epidemiological data linking HCV and diabetes... - Quantification of insulin-mediated glucose disposal in HIV-infected individuals: comparison of patients treated and untreated with protease inhibitorsGeorge Beatty
Department of Medicine, University of California San Francisco, San Francisco General Hospital, San Francisco, California 94110, USA
J Acquir Immune Defic Syndr 33:34-40. 2003..Finally, PI treatment may have an inhibitory effect on insulin secretion... - Hepatitis C in the setting of HIV co-infectionMandana Khalili
University of California San Francisco, San Francisco General Hospital, 1001 Potrero Avenue, NH 3D, San Francisco, CA 94110, USA
Microbes Infect 4:1247-51. 2002..However, additional information is required to assess the efficacy and safety of HCV therapy including possible interaction of HCV and HIV anti-viral medications in these co-infected individuals... 
Long-term histological effects of preemptive antiviral therapy in liver transplant recipients with hepatitis C virus infectionAlexander Kuo
Division of Gastroenterology, University of California, San Diego, CA, USA
Liver Transpl 14:1491-7. 2008..004). We conclude that preemptive antiviral therapy in virologic nonresponders delays the time to subsequent HCV treatment and may confer a reduced risk of fibrosis progression. Further study of preemptive antiviral therapy is warranted...- Comparison of surrogate and direct measurement of insulin resistance in chronic hepatitis C virus infection: impact of obesity and ethnicityKhoa D Lam
Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Hepatology 52:38-46. 2010..25-1.30, P = 0.005). CONCLUSION: Because of limitations of surrogate estimates, caution should be used in interpreting data evaluating insulin resistance especially in nonobese, nondiabetic patients with HCV... - Daily versus thrice-weekly interferon alfa-2b plus ribavirin for the treatment of chronic hepatitis C in HIV-infected persons: a multicenter randomized controlled trialMark S Sulkowski
Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
J Acquir Immune Defic Syndr 35:464-72. 2004..In conclusion, SVR was achieved in 19% of HIV/HCV coinfected subjects treated with daily IFN plus RBV, but the effectiveness of therapy was substantially diminished by relatively high rates of treatment-related toxicity...
Research Grants
- Insulin Resistance in HCV InfectionMandana Khalili; Fiscal Year: 2006..One of the important advantages of this study is that patients will be evaluated before and after HCV treatment. This will permit a direct evaluation of the causative role of HCV in promoting insulin resistance and hepatic steatosis. ..
- HCV-induced alterations in glucose metabolismMandana Khalili; Fiscal Year: 2006..The proposed studies will provide insight into the pathogenesis of diabetes in the setting of HCV because we will be able to directly evaluate alterations in glucose metabolism induced by HCV ..
- Impact of Hepatitis C on Insulin Sensitivity and Insulin Secretion in LatinosMandana Khalili; Fiscal Year: 2009....
- Impact of Hepatitis C on Insulin Sensitivity and Insulin Secretion in LatinosMandana Khalili; Fiscal Year: 2010....