J P Kesslak

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance?
    J P Kesslak
    Institute for Brain Aging and Department of Neurology, University of California, Irvine 92697 4540, USA
    Behav Neurosci 112:1012-9. 1998
  2. ncbi request reprint Spatial learning is delayed and brain-derived neurotrophic factor mRNA expression inhibited by administration of MK-801 in rats
    J Patrick Kesslak
    Institute for Brain Aging and Dementia, University of California, Irvine, CA 92697 4540, USA
    Neurosci Lett 353:95-8. 2003
  3. ncbi request reprint Assessment of behavior in animal models of spinal cord injury
    J Patrick Kesslak
    Institute for Brain Aging and Dementia, Department of Neurology, University of California at Irvine, Irvine, California 92697 4540, USA
    J Spinal Cord Med 26:323-8. 2003
  4. ncbi request reprint Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus
    N C Berchtold
    Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
    Neuroscience 133:853-61. 2005
  5. ncbi request reprint Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus
    N C Berchtold
    Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
    Eur J Neurosci 14:1992-2002. 2001
  6. ncbi request reprint Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain
    Joseph H Su
    Institute for Brain Aging and Dementia, University of California at Irvine, 92697 4540, USA
    Acta Neuropathol 104:1-6. 2002
  7. ncbi request reprint Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum
    Nicole C Berchtold
    Institute for Brain Aging and Dementia, University of California, Irvine, California, 92697 4540, USA
    J Neurosci Res 68:511-21. 2002
  8. ncbi request reprint Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
    Salvatore Oddo
    Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA 92697, USA
    Neuron 43:321-32. 2004

Detail Information

Publications8

  1. ncbi request reprint Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance?
    J P Kesslak
    Institute for Brain Aging and Department of Neurology, University of California, Irvine 92697 4540, USA
    Behav Neurosci 112:1012-9. 1998
    ..Furthermore, behaviors such as physical activity and learning may help maintain and protect neurons at risk in aging and neurodegenerative disease via increased BDNF expression...
  2. ncbi request reprint Spatial learning is delayed and brain-derived neurotrophic factor mRNA expression inhibited by administration of MK-801 in rats
    J Patrick Kesslak
    Institute for Brain Aging and Dementia, University of California, Irvine, CA 92697 4540, USA
    Neurosci Lett 353:95-8. 2003
    ..Increases in BDNF and NMDA activity may be significant components in learning and memory, and modulation of these systems may be beneficial for developing strategies to improve cognitive function...
  3. ncbi request reprint Assessment of behavior in animal models of spinal cord injury
    J Patrick Kesslak
    Institute for Brain Aging and Dementia, Department of Neurology, University of California at Irvine, Irvine, California 92697 4540, USA
    J Spinal Cord Med 26:323-8. 2003
    ..The appropriate use and interpretation of these methods is critical for proper study design, interpretation of experimental results, and extrapolation to clinical relevance...
  4. ncbi request reprint Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus
    N C Berchtold
    Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
    Neuroscience 133:853-61. 2005
    ..These findings are clinically important because they provide guidelines for optimizing the design of exercise and rehabilitation programs, in order to promote hippocampal function...
  5. ncbi request reprint Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus
    N C Berchtold
    Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
    Eur J Neurosci 14:1992-2002. 2001
    ..The interaction of estrogen, physical activity and hippocampal BDNF is likely to be an important issue for maintenance of brain health, plasticity and general well-being, particularly in women...
  6. ncbi request reprint Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain
    Joseph H Su
    Institute for Brain Aging and Dementia, University of California at Irvine, 92697 4540, USA
    Acta Neuropathol 104:1-6. 2002
    ..A caspase-cleavage product of fodrin that accumulates in many AD and DS neurons is not present in GVD granules. These data support a role for the activation of apoptotic mechanisms in selective compartments exhibiting GVD...
  7. ncbi request reprint Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum
    Nicole C Berchtold
    Institute for Brain Aging and Dementia, University of California, Irvine, California, 92697 4540, USA
    J Neurosci Res 68:511-21. 2002
    ..These results are discussed in relation to their implications for aging and Alzheimer's disease...
  8. ncbi request reprint Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
    Salvatore Oddo
    Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA 92697, USA
    Neuron 43:321-32. 2004
    ..These findings indicate that Abeta immunization may be useful for clearing both hallmark lesions of AD, provided that intervention occurs early in the disease course...