Berit Kerner

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Propensity score analysis in the Genetic Analysis Workshop 17 simulated data set on independent individuals
    Chen Min Lin
    Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, 695 Charles E, Young Drive South, Los Angeles, CA 90095 1761, USA
    BMC Proc 5:S71. 2011
  2. pmc Genome-wide association study in bipolar patients stratified by co-morbidity
    Berit Kerner
    Department of Psychiatry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 6:e28477. 2011
  3. pmc A multilevel linear mixed model of the association between candidate genes and weight and body mass index using the Framingham longitudinal family data
    Jian An Luan
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Hills Road, Cambridge CB2 0QQ, UK
    BMC Proc 3:S115. 2009
  4. ncbi request reprint Evidence of linkage to psychosis on chromosome 5q33-34 in pedigrees ascertained for bipolar disorder
    Berit Kerner
    Department of Psychiatry and Biobehavioral Sciences, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, CA 90095 1761, USA
    Am J Med Genet B Neuropsychiatr Genet 144:74-8. 2007
  5. pmc Co-regulation and multilocus determinants of gene expression in humans
    Berit Kerner
    Center for Neurobehavioral Genetics, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, 695 Charles E, Young Drive South, Los Angeles, California 90095 1761, USA
    BMC Proc 1:S88. 2007
  6. doi request reprint Polymorphisms in the GRIA1 gene region in psychotic bipolar disorder
    Berit Kerner
    Center for Neurobehavioral Genetics, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, 90095 1761, USA
    Am J Med Genet B Neuropsychiatr Genet 150:24-32. 2009
  7. pmc Growth mixture modelling in families of the Framingham Heart Study
    Berit Kerner
    Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, 695 Charles E Young Drive South, Room 4357B, Box 951761, Los Angeles, California 90095 1761, USA
    BMC Proc 3:S114. 2009
  8. pmc Use of longitudinal data in genetic studies in the genome-wide association studies era: summary of Group 14
    Berit Kerner
    Department of Psychiatry, University of California, Los Angeles, California, USA
    Genet Epidemiol 33:S93-8. 2009
  9. ncbi request reprint Summary of Genetic Analysis Workshop 15: Group 9 linkage analysis of the CEPH expression data
    Ellen M Wijsman
    Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Genet Epidemiol 31:S75-85. 2007

Collaborators

Detail Information

Publications9

  1. pmc Propensity score analysis in the Genetic Analysis Workshop 17 simulated data set on independent individuals
    Chen Min Lin
    Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, 695 Charles E, Young Drive South, Los Angeles, CA 90095 1761, USA
    BMC Proc 5:S71. 2011
    ....
  2. pmc Genome-wide association study in bipolar patients stratified by co-morbidity
    Berit Kerner
    Department of Psychiatry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 6:e28477. 2011
    ..Bipolar disorder is a severe psychiatric disorder with high heritability. Co-morbid conditions are common and might define latent subgroups of patients that are more homogeneous with respect to genetic risk factors...
  3. pmc A multilevel linear mixed model of the association between candidate genes and weight and body mass index using the Framingham longitudinal family data
    Jian An Luan
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Hills Road, Cambridge CB2 0QQ, UK
    BMC Proc 3:S115. 2009
    ..Linkage disequilibrium (LD) between the two FTO SNPs was strong (D' = 0.997, r2 = 0.875) but their haplotype was not significantly associated with either weight or BMI. The two SNPs near MC4R were in weak LD (D' = 0.487, r2 = 0.166)...
  4. ncbi request reprint Evidence of linkage to psychosis on chromosome 5q33-34 in pedigrees ascertained for bipolar disorder
    Berit Kerner
    Department of Psychiatry and Biobehavioral Sciences, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, CA 90095 1761, USA
    Am J Med Genet B Neuropsychiatr Genet 144:74-8. 2007
    ..This finding is consistent with the hypothesis that susceptibility to psychosis may characterize at least a subtype of bipolar disorder...
  5. pmc Co-regulation and multilocus determinants of gene expression in humans
    Berit Kerner
    Center for Neurobehavioral Genetics, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, 695 Charles E, Young Drive South, Los Angeles, California 90095 1761, USA
    BMC Proc 1:S88. 2007
    ..CONCLUSION : The complex nature of gene regulation can be explored by linkage analysis with single-nucleotide polymorphisms followed by multivariate methods to explore co-regulation...
  6. doi request reprint Polymorphisms in the GRIA1 gene region in psychotic bipolar disorder
    Berit Kerner
    Center for Neurobehavioral Genetics, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, 90095 1761, USA
    Am J Med Genet B Neuropsychiatr Genet 150:24-32. 2009
    ..Our findings suggest that variations in this receptor may contribute to the pathophysiology of BP with psychotic features in some families...
  7. pmc Growth mixture modelling in families of the Framingham Heart Study
    Berit Kerner
    Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, 695 Charles E Young Drive South, Room 4357B, Box 951761, Los Angeles, California 90095 1761, USA
    BMC Proc 3:S114. 2009
    ....
  8. pmc Use of longitudinal data in genetic studies in the genome-wide association studies era: summary of Group 14
    Berit Kerner
    Department of Psychiatry, University of California, Los Angeles, California, USA
    Genet Epidemiol 33:S93-8. 2009
    ..4) Estimation of the population impact of genomic risk variants could be more precise. The challenges and computational complexity demanded by genome-wide single-nucleotide polymorphism data were also discussed...
  9. ncbi request reprint Summary of Genetic Analysis Workshop 15: Group 9 linkage analysis of the CEPH expression data
    Ellen M Wijsman
    Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Genet Epidemiol 31:S75-85. 2007
    ..Finally, there were computational and analytic challenges in working with a large public data set, along with need for more data documentation...

Research Grants4

  1. Symptom Dimensions in Psychosis
    Berit Kerner; Fiscal Year: 2007
    ..The mentorship of Dr. Nelson Freimer, Dr. Andrew Leuchter and Dr. Bengt Muthen, who are all experts in overlapping aspects of this proposal, will guarantee the success of the training, complemented by coursework and conferences. ..
  2. Parsing of Bipolar Disorders and Schizophrenia: A Latent Class Approach
    Berit Kerner; Fiscal Year: 2010
    ....
  3. Parsing of Bipolar Disorders and Schizophrenia: A Latent Class Approach
    Berit Kerner; Fiscal Year: 2011
    ..Identifying genomic variants associated with certain clinical subgroups of patients would improve our understanding of the underlying patho-physiology of these disorders;it would also help in early diagnosis and more specific treatment. ..