K B Kern

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. pmc Continued breathing followed by gasping or apnea in a swine model of ventricular fibrillation cardiac arrest
    Mathias Zuercher
    University of Arizona Sarver Heart Center, Tucson, AZ, USA
    BMC Cardiovasc Disord 10:36. 2010
  2. ncbi request reprint Myocardial perfusion during cardiopulmonary resuscitation (CPR): effects of 10, 25 and 50% coronary stenoses
    K B Kern
    Department of Medicine, University of Arizona College of Medicine, Tucson 85724, USA
    Resuscitation 38:107-11. 1998
  3. ncbi request reprint An alternative approach to advancing resuscitation science
    Karl B Kern
    College of Medicine, Sarver Heart Center, University of Arizona, 1501 N Campbell Avenue, Tucson, AZ 85724, USA
    Resuscitation 64:261-8. 2005
  4. ncbi request reprint Limiting interruptions of chest compressions during cardiopulmonary resuscitation
    Karl B Kern
    University of Arizona, Sarver Heart Center, Tucson, AZ 85724, USA
    Resuscitation 58:273-4. 2003
  5. ncbi request reprint Postresuscitation myocardial dysfunction
    Karl B Kern
    Department of Medicine, Sarver Heart Center, University of Arizona College of Medicine, University Medical Center, Tucson, Arizona, USA
    Cardiol Clin 20:89-101. 2002
  6. doi request reprint Post-resuscitation myocardial microcirculatory dysfunction is ameliorated with eptifibatide
    Karl B Kern
    College of Medicine, Cardiac Catheterization Laboratories, Sarver Heart Center, University of Arizona, 1501 N Campbell Avenue, Tucson, AZ 85724, USA
    Resuscitation 82:85-9. 2011
  7. ncbi request reprint Importance of continuous chest compressions during cardiopulmonary resuscitation: improved outcome during a simulated single lay-rescuer scenario
    Karl B Kern
    University of Arizona Sarver Heart Center, Section of Cardiology, 85724, USA
    Circulation 105:645-9. 2002
  8. ncbi request reprint Optimizing ventilation in conjunction with phased chest and abdominal compression-decompression (Lifestick) resuscitation
    Karl B Kern
    Departments of Medicine and Pediatrics, University of Arizona Sarver Heart Center, Tucson, AZ, USA
    Resuscitation 52:91-100. 2002
  9. ncbi request reprint Cardiopulmonary resuscitation without ventilation
    K B Kern
    Section of Cardiology, Sarver Heart Center, University of Arizona, Tucson, 85724, USA
    Crit Care Med 28:N186-9. 2000
  10. ncbi request reprint Postresuscitation left ventricular systolic and diastolic dysfunction. Treatment with dobutamine
    K B Kern
    University Heart Center, Tucson, AZ, USA
    Circulation 95:2610-3. 1997

Collaborators

Detail Information

Publications80

  1. pmc Continued breathing followed by gasping or apnea in a swine model of ventricular fibrillation cardiac arrest
    Mathias Zuercher
    University of Arizona Sarver Heart Center, Tucson, AZ, USA
    BMC Cardiovasc Disord 10:36. 2010
    ..Continued breathing following ventricular fibrillation has here-to-fore not been described...
  2. ncbi request reprint Myocardial perfusion during cardiopulmonary resuscitation (CPR): effects of 10, 25 and 50% coronary stenoses
    K B Kern
    Department of Medicine, University of Arizona College of Medicine, Tucson 85724, USA
    Resuscitation 38:107-11. 1998
    ..Since the vast majority of cardiac arrest victims have coronary artery disease, careful attention to maximizing myocardial blood flow during CPR is needed...
  3. ncbi request reprint An alternative approach to advancing resuscitation science
    Karl B Kern
    College of Medicine, Sarver Heart Center, University of Arizona, 1501 N Campbell Avenue, Tucson, AZ 85724, USA
    Resuscitation 64:261-8. 2005
    ..A local change in our previous resuscitation protocols had been instituted based upon this historical database information...
  4. ncbi request reprint Limiting interruptions of chest compressions during cardiopulmonary resuscitation
    Karl B Kern
    University of Arizona, Sarver Heart Center, Tucson, AZ 85724, USA
    Resuscitation 58:273-4. 2003
  5. ncbi request reprint Postresuscitation myocardial dysfunction
    Karl B Kern
    Department of Medicine, Sarver Heart Center, University of Arizona College of Medicine, University Medical Center, Tucson, Arizona, USA
    Cardiol Clin 20:89-101. 2002
    ..Potential treatments include dobutamine, KATP channel activators, and 21-aminosteroids. In the author's efforts to improve long-term survival from cardiac arrest, more attention is needed to the postresuscitation period...
  6. doi request reprint Post-resuscitation myocardial microcirculatory dysfunction is ameliorated with eptifibatide
    Karl B Kern
    College of Medicine, Cardiac Catheterization Laboratories, Sarver Heart Center, University of Arizona, 1501 N Campbell Avenue, Tucson, AZ 85724, USA
    Resuscitation 82:85-9. 2011
    ..Therefore, we evaluated such inhibition with eptifibatide for its effect on myocardial microcirculation function post-cardiac arrest and resuscitation...
  7. ncbi request reprint Importance of continuous chest compressions during cardiopulmonary resuscitation: improved outcome during a simulated single lay-rescuer scenario
    Karl B Kern
    University of Arizona Sarver Heart Center, Section of Cardiology, 85724, USA
    Circulation 105:645-9. 2002
    ..Whether such hemodynamic compromise from pausing to ventilate is enough to affect outcome is unknown...
  8. ncbi request reprint Optimizing ventilation in conjunction with phased chest and abdominal compression-decompression (Lifestick) resuscitation
    Karl B Kern
    Departments of Medicine and Pediatrics, University of Arizona Sarver Heart Center, Tucson, AZ, USA
    Resuscitation 52:91-100. 2002
    ..Optimal ventilation strategy when using the LS device at 60 compressions per min appears to be 5:1 S. Such data is important for conducting clinical trials with this new CPR adjunct...
  9. ncbi request reprint Cardiopulmonary resuscitation without ventilation
    K B Kern
    Section of Cardiology, Sarver Heart Center, University of Arizona, Tucson, 85724, USA
    Crit Care Med 28:N186-9. 2000
    ..Manikin "exit testing" at course completion has revealed significant advantages of the simplified approach compared with standard CPR courses for the lay public...
  10. ncbi request reprint Postresuscitation left ventricular systolic and diastolic dysfunction. Treatment with dobutamine
    K B Kern
    University Heart Center, Tucson, AZ, USA
    Circulation 95:2610-3. 1997
    ..Treatment of such postresuscitation myocardial dysfunction has not been examined previously...
  11. ncbi request reprint Efficacy of chest compression-only BLS CPR in the presence of an occluded airway
    K B Kern
    University of Arizona Sarver Heart Center, University of Arizona College of Medicine, Tucson 85724 5037, USA
    Resuscitation 39:179-88. 1998
    ..5 min of cardiac arrest. Such a strategy for the first minutes of cardiac arrest, particularly before professional help arrives, has several advantages including increased acceptability to the lay public...
  12. ncbi request reprint Adverse hemodynamic effects of interrupting chest compressions for rescue breathing during cardiopulmonary resuscitation for ventricular fibrillation cardiac arrest
    R A Berg
    University of Arizona College of Medicine, Steele Memorial Children s Research Center, Department of Pediatrics, Sarver Heart Center, Tucson, Arizona, USA
    Circulation 104:2465-70. 2001
    ....
  13. ncbi request reprint Assisted ventilation does not improve outcome in a porcine model of single-rescuer bystander cardiopulmonary resuscitation
    R A Berg
    Department of Pediatrics, Steele Memorial Children s Research Center, Tucson, Ariz, USA
    Circulation 95:1635-41. 1997
    ..We evaluated the need for assisted ventilation during simulated single-rescuer bystander CPR in a swine model of prehospital cardiac arrest...
  14. ncbi request reprint Simulated mouth-to-mouth ventilation and chest compressions (bystander cardiopulmonary resuscitation) improves outcome in a swine model of prehospital pediatric asphyxial cardiac arrest
    R A Berg
    University of Arizona Heart Center, Tucson, AZ, USA
    Crit Care Med 27:1893-9. 1999
    ..To compare the efficacy of four methods of simulated single-rescuer bystander cardiopulmonary resuscitation (CPR) in a clinically relevant swine model of prehospital pediatric asphyxial cardiac arrest...
  15. ncbi request reprint Assisted ventilation during 'bystander' CPR in a swine acute myocardial infarction model does not improve outcome
    R A Berg
    University of Arizona Heart Center, and Department of Pediatrics, University of Arizona College of Medicine, Tucson, USA
    Circulation 96:4364-71. 1997
    ..We evaluated the need for assisted ventilation during simulated single-rescuer bystander CPR in a swine myocardial infarction model of prehospital cardiac arrest...
  16. ncbi request reprint Vasopressin versus epinephrine during cardiopulmonary resuscitation: a randomized swine outcome study
    S I Babar
    Sarver Heart Center, The University of Arizona, Pediatrics 3302, Department of Medicine, The University of Arizona College of Medicine, Tuscon, AZ 85724 5073, USA
    Resuscitation 41:185-92. 1999
    ..24. In conclusion, vasopressin administration during CPR improved coronary perfusion pressure, but did not result in statistically significant outcome improvement...
  17. ncbi request reprint Ventricular fibrillation in a swine model of acute pediatric asphyxial cardiac arrest
    R A Berg
    Department of Pediatrics, University of Arizona College of Medicine, Tucson 85724 5073, USA
    Resuscitation 33:147-53. 1996
    ..CONCLUSION: VF occurs frequently in this piglet model of prolonged asphyxial cardiac arrest, consistent with recent observations in pediatric prehospital cardiac arrests. VF occurred late in the asphyxial process...
  18. ncbi request reprint Comparison of standard CPR versus diffuse and stacked hand position interposed abdominal compression-CPR in a swine model
    Lyndon Xavier
    Sarver Heart Center, University of Arizona, 1501 N Campbell Ave, Tucson, AZ 85724, USA
    Resuscitation 59:337-44. 2003
    ..There was a trend towards better outcomes with stacked hands IAC-CPR with 90 versus 70% survival with STD-CPR...
  19. ncbi request reprint Post-resuscitation right ventricular dysfunction: delineation and treatment with dobutamine
    Robyn J Meyer
    Department of Pediatrics, University of Arizona Sarver Heart Center, University of Arizona College of Medicine, Tucson, AZ, USA
    Resuscitation 55:187-91. 2002
    ..The purposes of this study were to examine right ventricular function following resuscitation and determine whether dobutamine would improve post-resuscitation right ventricular function...
  20. ncbi request reprint Optimal dosing of dobutamine for treating post-resuscitation left ventricular dysfunction
    Alejandro Vasquez
    Section of Cardiology, Department of Medicine, Sarver Heart Center, University of Arizona College of Medicine, 1501 N Campbell Avenue, Tucson, AZ 85724, USA
    Resuscitation 61:199-207. 2004
    ..This study was designed to determine the optimal dose of dobutamine in the treatment of post-resuscitation left ventricular dysfunction...
  21. doi request reprint Continuous chest compression resuscitation in arrested swine with upper airway inspiratory obstruction
    Gordon A Ewy
    University of Arizona College of Medicine s Sarver Heart Center, Tucson, AZ, USA
    Resuscitation 81:585-90. 2010
    ..This study was designed to compare 24-h survival rates and neurological function of swine in cardiac arrest treated with one of three forms of simulated basic life support CPR...
  22. ncbi request reprint Continuous passive oxygen insufflation results in a similar outcome to positive pressure ventilation in a swine model of out-of-hospital ventricular fibrillation
    Melinda M Hayes
    Department of Anesthesiology, University of Arizona, College of Medicine, Sarver Heart Center, Tucson, AZ 85724, USA
    Resuscitation 74:357-65. 2007
    ..The deleterious effects of positive pressure ventilation may be prevented by substituting passive oxygen insufflation during advanced cardiac life support (ACLS) cardiopulmonary resuscitation (CPR)...
  23. ncbi request reprint Single-rescuer cardiopulmonary resuscitation: 'two quick breaths'--an oxymoron
    Joseph W Heidenreich
    University of Arizona College of Medicine, University of Arizona Sarver Heart Center, 1501 N Campbell Ave, Tucson, AZ 85724, USA
    Resuscitation 62:283-9. 2004
    ..New recommendations for single-rescuer CPR should be considered that emphasize uninterrupted chest compressions...
  24. ncbi request reprint Effect of vasopressin on postresuscitation ventricular function: unknown consequences of the recent Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
    Karl B Kern
    University of Arizona College of Medicine, Sarver Heart Center, Tucson, AZ, USA
    Crit Care Med 32:S393-7. 2004
    ..To compare the effect on postresuscitation left ventricular function of vasopressin vs. epinephrine used during cardiopulmonary resuscitation in a swine model of prolonged prehospital ventricular fibrillation...
  25. ncbi request reprint Cardiocerebral resuscitation for cardiac arrest
    Gordon A Ewy
    University of Arizona College of Medicine, Tucson, Ariz, USA
    Am J Med 119:6-9. 2006
    ..There is also emphasis on chest compressions before defibrillation in circulatory phase of cardiac arrest. CCR was initiated in Tucson, Arizona, in November 2003, and in two rural Wisconsin counties in early 2004...
  26. ncbi request reprint Cardiopulmonary Resuscitation Guidelines 2000 update: what's happened since?
    Lyndon C Xavier
    Department of Medicine, Sarver Heart Center, University of Arizona, Tucson, Arizona 85724, USA
    Curr Opin Crit Care 9:218-21. 2003
    ..To examine the literature for new resuscitation science since the publication of the Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiac Care...
  27. pmc Leaning during chest compressions impairs cardiac output and left ventricular myocardial blood flow in piglet cardiac arrest
    Mathias Zuercher
    University of Arizona Sarver Heart Center, Tucson, AZ, USA
    Crit Care Med 38:1141-6. 2010
    ..We evaluated the hemodynamic effect of 10% or 20% lean during piglet cardiopulmonary resuscitation...
  28. ncbi request reprint Myocardial perfusion pressure: a predictor of 24-hour survival during prolonged cardiac arrest in dogs
    K B Kern
    Department of Internal Medicine, University of Arizona College of Medicine, Veterans Administration Medical Center, Tucson
    Resuscitation 16:241-50. 1988
    ..Myocardial perfusion pressure is a useful index of CPR effectiveness and therefore may be a useful guide in helping to optimize resuscitation efforts...
  29. pmc Mild hypothermia delays the development of stone heart from untreated sustained ventricular fibrillation--a cardiovascular magnetic resonance study
    Vincent L Sorrell
    Department of Medicine, Sarver Heart Center, University of Arizona College of Medicine, Tucson, Arizona, USA
    J Cardiovasc Magn Reson 13:17. 2011
    ..Stone heart' resulting from ischemic contracture of the myocardium, precludes successful resuscitation from ventricular fibrillation (VF). We hypothesized that mild hypothermia might slow the progression to stone heart...
  30. doi request reprint Direction of signal recording affects waveform characteristics of ventricular fibrillation in humans undergoing defibrillation testing during ICD implantation
    Julia H Indik
    The Sarver Heart Center at The University of Arizona College of Medicine, Tucson, AZ 85724 5037, USA
    Resuscitation 78:38-45. 2008
    ..However, it is unknown whether the VF waveform is dependent on recording direction, which could be altered by incorrect placement of AED patches...
  31. pmc Myocardial cytokine IL-8 and nitric oxide synthase activity during and after resuscitation: preliminary observations in regards to post-resuscitation myocardial dysfunction
    Karl B Kern
    Sarver Heart Center, University of Arizona College of Medicine, 1501 N Campbell, Tucson, AZ 85724, USA
    Resuscitation 77:401-9. 2008
    ....
  32. ncbi request reprint Improved neurological outcome with continuous chest compressions compared with 30:2 compressions-to-ventilations cardiopulmonary resuscitation in a realistic swine model of out-of-hospital cardiac arrest
    Gordon A Ewy
    University of Arizona Sarver Heart Center, University of Arizona College of Medicine, Tucson AZ 85724, USA
    Circulation 116:2525-30. 2007
    ....
  33. ncbi request reprint Ventricular fibrillation frequency characteristics are altered in acute myocardial infarction
    Julia H Indik
    The Sarver Heart Center, The University of Arizona College of Medicine, Tucson, AZ, USA
    Crit Care Med 35:1133-8. 2007
    ..We hypothesized that an acute myocardial infarction may alter the frequency content of ventricular fibrillation...
  34. ncbi request reprint Cardiac magnetic resonance imaging investigation of sustained ventricular fibrillation in a swine model--with a focus on the electrical phase
    Vincent L Sorrell
    Department of Medicine, Division of Cardiology, Sarver Heart Center, University of Arizona, Tucson, AZ 85724 5073, United States
    Resuscitation 73:279-86. 2007
    ..We also present details of our CPR research imaging program to facilitate this avenue of clinically important research...
  35. pmc Immediate post-shock chest compressions improve outcome from prolonged ventricular fibrillation
    Robert A Berg
    The University of Arizona College of Medicine, Sarver Heart Center, Tucson, AZ 85724 5017, USA
    Resuscitation 78:71-6. 2008
    ..e., delayed post-shock compressions) associated with AED use...
  36. pmc Attenuating the defibrillation dosage decreases postresuscitation myocardial dysfunction in a swine model of pediatric ventricular fibrillation
    Marc D Berg
    University of Arizona Steele Children s Research Center, Tucson, AZ, USA
    Pediatr Crit Care Med 9:429-34. 2008
    ..The objective was to investigate whether unattenuated (adult) dose biphasic defibrillation results in greater postresuscitation myocardial dysfunction and damage than attenuated (pediatric) defibrillation...
  37. pmc The influence of myocardial substrate on ventricular fibrillation waveform: a swine model of acute and postmyocardial infarction
    Julia H Indik
    Sarver Heart Center at The University of Arizona College of Medicine, Tucson, AZ, USA
    Crit Care Med 36:2136-42. 2008
    ..We hypothesized that ventricular fibrillation is altered by myocardial infarction and varies from the acute to postmyocardial infarction periods...
  38. ncbi request reprint Myocardial microcirculatory dysfunction after prolonged ventricular fibrillation and resuscitation
    Karl B Kern
    Department of Medicine, University of Arizona Sarver Heart Center, University of Arizona, Tucson, AZ, USA
    Crit Care Med 36:S418-21. 2008
    ..A potential common pathway for postischemia/reperfusion end-organ dysfunction is microvascular injury. We hypothesized that myocardial microcirculatory function is markedly abnormal in the postresuscitation period...
  39. doi request reprint Glucagon-like peptide-1 (GLP-1) attenuates post-resuscitation myocardial microcirculatory dysfunction
    Betsy B Dokken
    Department of Medicine, University of Arizona, Tucson, AZ, USA
    Resuscitation 81:755-60. 2010
    ..The aim of this study was to determine if glucagon-like peptide-1 (GLP-1) improves post-resuscitation myocardial microcirculatory function...
  40. doi request reprint Emergent percutaneous coronary intervention for resuscitated victims of out-of-hospital cardiac arrest
    Karl B Kern
    Sarver Heart Center at The University of Arizona College of Medicine, Tucson, Arizona 85724, USA
    Catheter Cardiovasc Interv 75:616-24. 2010
    ..Even those without ST elevation on their postresuscitation ECG can greatly benefit from timely induction of hypothermia and early angiography/PCI...
  41. pmc Preshock cardiopulmonary resuscitation worsens outcome from circulatory phase ventricular fibrillation with acute coronary artery obstruction in swine
    Julia H Indik
    Sarver Heart Center, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona 85724 5037, USA
    Circ Arrhythm Electrophysiol 2:179-84. 2009
    ..We hypothesized that chest compressions before defibrillation in a swine model of acute myocardial ischemia would also increase VF median frequency and improve resuscitation outcome...
  42. pmc Predictors of resuscitation outcome in a swine model of VF cardiac arrest: A comparison of VF duration, presence of acute myocardial infarction and VF waveform
    Julia H Indik
    The Sarver Heart Center, The University of Arizona College of Medicine, 1501 N Campbell Ave, Tucson, AZ 85724 5037, United States
    Resuscitation 80:1420-3. 2009
    ..We hypothesized that resuscitation of VF to ROSC within 3min is predicted by the VF waveform, independent of untreated VF duration or presence of acute MI...
  43. doi request reprint Passive oxygen insufflation is superior to bag-valve-mask ventilation for witnessed ventricular fibrillation out-of-hospital cardiac arrest
    Bentley J Bobrow
    Arizona Department of Health Services Bureau of Emergency Medical Services and Trauma System, Phoenix, AZ, USA
    Ann Emerg Med 54:656-662.e1. 2009
    ..We compare the adjusted neurologically intact survival of out-of-hospital cardiac arrest patients receiving initial passive ventilation with those receiving initial bag-valve-mask ventilation...
  44. doi request reprint Recent advances in cardiopulmonary resuscitation: cardiocerebral resuscitation
    Gordon A Ewy
    University of Arizona Sarver Heart Center, University of Arizona College of Medicine, Tucson, AZ 85724, USA
    J Am Coll Cardiol 53:149-57. 2009
    ..Endotracheal intubation is delayed, excessive ventilations are avoided, and early-administration epinephrine is advocated...
  45. pmc Gasping during cardiac arrest in humans is frequent and associated with improved survival
    Bentley J Bobrow
    Department of Health Services, Bureau of Emergency Medical Services and Trauma System, Tucson, Arizona, USA
    Circulation 118:2550-4. 2008
    ..The incidence and significance of gasping after cardiac arrest in humans are controversial...
  46. doi request reprint Predictors of resuscitation in a swine model of ischemic and nonischemic ventricular fibrillation cardiac arrest: superiority of amplitude spectral area and slope to predict a return of spontaneous circulation when resuscitation efforts are prolonged
    Julia H Indik
    Sarver Heart Center, Department of Internal Medicine, The University of Arizona College of Medicine, Tucson, AZ, USA
    Crit Care Med 38:2352-7. 2010
    ....
  47. ncbi request reprint Precountershock cardiopulmonary resuscitation improves initial response to defibrillation from prolonged ventricular fibrillation: a randomized, controlled swine study
    Robert A Berg
    Steele Memorial Children s Research Center and Department of Pediatrics, University of Arizona College of Medicine, Tucson, 85724 5073, USA
    Crit Care Med 32:1352-7. 2004
    ..To compare immediate countershocks (defibrillation 1st) with precountershock cardiopulmonary resuscitation (CPR 1st) for prolonged ventricular fibrillation (VF)...
  48. ncbi request reprint Post-shock chest compression delays with automated external defibrillator use
    Marc D Berg
    Department of Pediatrics, Steele Memorial Children s Research Center, Sarver Heart Center, University of Arizona College of Medicine, P O Box 245073, 1501 N Campbell Avenue, Tucson, AZ 85724, USA
    Resuscitation 64:287-91. 2005
    ..In particular, the mean interval from first AED shock to first post-shock compressions was 46+/-6s. We hypothesized that the delay from shock to provision of chest compressions is similar in the out-of-hospital setting...
  49. ncbi request reprint Automated external defibrillation versus manual defibrillation for prolonged ventricular fibrillation: lethal delays of chest compressions before and after countershocks
    Robert A Berg
    Sarver Heart Center, University of Arizona College of Medicine, Tucson, AZ 85724 5073, USA
    Ann Emerg Med 42:458-67. 2003
    ....
  50. ncbi request reprint Better outcome after pediatric defibrillation dosage than adult dosage in a swine model of pediatric ventricular fibrillation
    Robert A Berg
    University of Arizona Steele Memorial Children s Research Center, Tucson, Arizona, USA
    J Am Coll Cardiol 45:786-9. 2005
    ..This study was designed to compare outcome after adult defibrillation dosing versus pediatric dosing in a piglet model of prolonged prehospital ventricular fibrillation (VF)...
  51. ncbi request reprint Cardiopulmonary resuscitation with a novel chest compression device in a porcine model of cardiac arrest: improved hemodynamics and mechanisms
    Henry R Halperin
    Johns Hopkins University, Department of Medicine, Baltimore, Maryland, USA
    J Am Coll Cardiol 44:2214-20. 2004
    ..Sunnyvale, California) compared with conventional cardiopulmonary resuscitation (C-CPR)...
  52. ncbi request reprint Precountershock cardiopulmonary resuscitation improves ventricular fibrillation median frequency and myocardial readiness for successful defibrillation from prolonged ventricular fibrillation: a randomized, controlled swine study
    Robert Allen Berg
    Steele Memorial Children s Research Center and the Department of Pediatrics, University of Arizona College of Medicine, Tucson 85724 5073, USA
    Ann Emerg Med 40:563-70. 2002
    ..After prolonged ventricular fibrillation (VF), precountershock cardiopulmonary resuscitation (CPR) will improve myocardial "readiness" for defibrillation compared with immediate defibrillation...
  53. ncbi request reprint Images in cardiovascular medicine. Continuous cardiac magnetic resonance imaging during untreated ventricular fibrillation
    Vincent L Sorrell
    University of Arizona College of Medicine, Department of Medicine, Sarver Heart Center, Tucson, Ariz 85724 5073, USA
    Circulation 111:e294. 2005
  54. ncbi request reprint Survival and neurologic outcome after cardiopulmonary resuscitation with four different chest compression-ventilation ratios
    Arthur B Sanders
    Sarver Heart Center, the Arizona Emergency Medicine Research Center, Department of Emergency Medicine, University of Arizona, Tucson, USA
    Ann Emerg Med 40:553-62. 2002
    ..We determine 24-hour survival and neurologic outcome, comparing 4 different chest compression-ventilation CPR ratios in a porcine model of prolonged cardiac arrest and bystander CPR...
  55. ncbi request reprint Uninterrupted chest compression CPR is easier to perform and remember than standard CPR
    Joseph W Heidenreich
    Sarver Heart Center, College of Medicine, University of Arizona, 451 W Yucca Ct, 214, Tucson, AZ 85704, USA
    Resuscitation 63:123-30. 2004
    ..It delivers substantially more compressions per minute and may be easier to remember and perform than standard CPR...
  56. ncbi request reprint Treatment of post resuscitation myocardial dysfunction: aortic counterpulsation versus dobutamine
    Heath Tennyson
    Department of Medicine, Section of Cardiology, The Sarver Heart Center, University of Arizona College of Medicine, 1501 N Campbell Avenue, Tucson, AZ 95724, USA
    Resuscitation 54:69-75. 2002
    ..Post resuscitation myocardial stunning is well described and recognized as a significant contributor to poor long-term outcome following cardiac arrest. Optimal strategies for treatment have not been determined...
  57. ncbi request reprint Ventricular fibrillation waveform characteristics are different in ischemic heart failure compared with structurally normal hearts
    Julia H Indik
    Sarver Heart Center, University of Arizona College of Medicine, 1501 N Campbell Avenue, Tucson, AZ 85724 5037, USA
    Resuscitation 69:471-7. 2006
    ..We hypothesized that ischemic heart failure might alter the waveform content of ventricular fibrillation compared with normal hearts, complicating the determination of VF duration...
  58. ncbi request reprint Attenuated adult biphasic shocks compared with weight-based monophasic shocks in a swine model of prolonged pediatric ventricular fibrillation
    Robert A Berg
    The University of Arizona Steele Memorial Children s Research Center, Tuscon, AZ 85724 5073, USA
    Resuscitation 61:189-97. 2004
    ..To compare the safety and efficacy of attenuated adult biphasic shocks with standard monophasic weight-based shocks in a piglet model of prolonged prehospital ventricular fibrillation (VF)...
  59. ncbi request reprint Magnetic resonance imaging during untreated ventricular fibrillation reveals prompt right ventricular overdistention without left ventricular volume loss
    Robert A Berg
    University of Arizona College of Medicine, Steele Memorial Children s Research Center and Department of Pediatrics, Tucson, AZ 85724 5073, USA
    Circulation 111:1136-40. 2005
    ..Therefore, inadequate left ventricular stroke volume after defibrillation from prolonged VF has been postulated as a major contributor to the development of pulseless rhythms...
  60. ncbi request reprint Interruptions of chest compressions during emergency medical systems resuscitation
    Terence D Valenzuela
    Emergency Medicine Research Center, University of Arizona, Tucson, AZ, USA
    Circulation 112:1259-65. 2005
    ..We hypothesized that interruptions of chest compressions occur commonly and for substantial periods during treatment of OOH cardiac arrest and could be contributing to the lack of improvement in resuscitation outcome...
  61. ncbi request reprint Single rescuer cardiopulmonary resuscitation: can anyone perform to the guidelines 2000 recommendations?
    Travis A Higdon
    University of Arizona College of Medicine, Sarver Heart Center, Tucson, AZ 85724, USA
    Resuscitation 71:34-9. 2006
    ..We hypothesized that trained professional rescuers would also take substantially longer then the Guidelines recommendation for delivering the two rescue breaths before every 15 compressions during simulated single rescuer BLS CPR...
  62. doi request reprint Metronome improves compression and ventilation rates during CPR on a manikin in a randomized trial
    Karl B Kern
    The University of Arizona Sarver Heart Center, Tucson, AZ, USA
    Resuscitation 81:206-10. 2010
    ..We hypothesized that a unique tock and voice metronome could prevent both suboptimal chest compression rates and hyperventilation...
  63. ncbi request reprint Optimum compression to ventilation ratios in CPR under realistic, practical conditions: a physiological and mathematical analysis
    Charles F Babbs
    Department of Basic Medical Sciences, Purdue University, 1426 Lynn Hall, West Lafayette, IN 47907 1246, USA
    Resuscitation 54:147-57. 2002
    ..The optimum value of a variable is that for which a desired result is maximized. Here the desired result is assumed to be either oxygen delivery to peripheral tissues or a combination of oxygen delivery and waste product removal...
  64. ncbi request reprint Acute ischemic syndromes. Adjunctive therapy
    Katherine A Littrell
    Genentech Cardiovascular Research, Inc, South San Francisco, California, USA
    Cardiol Clin 20:159-75, ix-x. 2002
    ..The adjunctive therapies are divided into early immediate treatment and then subsequent management in the acute care setting...
  65. ncbi request reprint Effect of amiodarone on haemodynamics during cardiopulmonary resuscitation in a canine model of resistant ventricular fibrillation
    Edison F Paiva
    Heart Institute, University of Sao Paulo School of Medicine, CEP 05411 001, SP, Sao Paulo, Brazil
    Resuscitation 58:203-8. 2003
    ..Our intention was to verify if amiodarone alone produced significantly lower resuscitation haemodynamics than did either adrenaline (epinephrine) alone or the combination of amiodarone and adrenaline...
  66. ncbi request reprint Preliminary in-hospital experience with a fully automatic external cardioverter-defibrillator
    André Moreira Bento
    Valvular Heart Disease Unit, Instituto do Coração InCor, University of Sao Paulo Medical School, Av Eneas de Carvalho Aguiar, 44, Sao Paulo, SP 05403 000, Brazil
    Resuscitation 63:11-6. 2004
    ..The delay between the arrhythmic event and intervention is still a challenge for clinical practice...
  67. doi request reprint Surviving cardiac arrest: location, location, location
    Arthur B Sanders
    JAMA 300:1462-3. 2008
  68. ncbi request reprint The Save Hearts in Arizona Registry and Education (SHARE) program: who is performing CPR and where are they doing it?
    Tyler Vadeboncoeur
    Department of Emergency Medicine, Mayo Clinic, Jacksonville, FL, USA
    Resuscitation 75:68-75. 2007
    ..Accordingly, layperson CPR is an integral component in the chain of survival for out-of-hospital cardiac arrest victims. The near statewide incidence and location of layperson CPR is unknown...
  69. ncbi request reprint Post-cardiac arrest myocardial dysfunction: adding insult to injury
    Robert A Berg
    Crit Care Med 36:351-2. 2008
  70. doi request reprint Minimally interrupted cardiac resuscitation by emergency medical services for out-of-hospital cardiac arrest
    Bentley J Bobrow
    Department of Emergency Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA
    JAMA 299:1158-65. 2008
    ..Out-of-hospital cardiac arrest is a major public health problem...
  71. doi request reprint Left ventricular systolic function and outcome after in-hospital cardiac arrest
    Maria M Gonzalez
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Circulation 117:1864-72. 2008
    ..The effect of prearrest left ventricular ejection fraction (LVEF) on outcome after cardiac arrest is unknown...
  72. ncbi request reprint Effects of intravenous arginine vasopressin on epicardial coronary artery cross sectional area in a swine resuscitation model
    Volker Wenzel
    Department of Anesthesiology and Critical Care Medicine, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    Resuscitation 64:219-26. 2005
    ....
  73. ncbi request reprint Antithrombotic therapies for cardiac arrest: have we missed the mark?
    Karl B Kern
    Crit Care Med 36:1016-8. 2008
  74. ncbi request reprint Trials of teaching methods in basic life support (4): comparison of simulated CPR performance at unannounced home testing after conventional or staged training
    Anna Smith
    The Pre hospital Emergency Research Unit, The University of Wales College of Medicine, Cardiff, UK
    Resuscitation 61:41-7. 2004
    ....
  75. ncbi request reprint ST-segment elevation myocardial infarction: recommendations on triage of patients to heart attack centers: is it time for a national policy for the treatment of ST-segment elevation myocardial infarction?
    Timothy D Henry
    Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, Minnesota 55407, USA
    J Am Coll Cardiol 47:1339-45. 2006
    ..We believe it is time to establish a national policy for treatment of patients with STEMI to develop a coordinated system of care similar to that of the level 1 trauma system...
  76. ncbi request reprint Advanced cardiac life support training improves long-term survival from in-hospital cardiac arrest
    Miguel Antonio Moretti
    Heart Institute INCOR at the University of Sao Paulo, Sao Paulo, Brazil
    Resuscitation 72:458-65. 2007
    ..In spite of the wide dissemination of ACLS training, it has been difficult to demonstrate improved outcome following such training...
  77. ncbi request reprint Therapeutic hypothermia after cardiac arrest
    Stephan A Padosch
    N Engl J Med 347:63-5; author reply 63-5. 2002
  78. ncbi request reprint Trials of teaching methods in basic life support (3): comparison of simulated CPR performance after first training and at 6 months, with a note on the value of re-training
    Douglas Chamberlain
    The Pre hospital Emergency Research Unit, Lansdowne Hospital, Sanatorium Road, Canton, Cardiff, Wales, UK
    Resuscitation 53:179-87. 2002
    ..The value of conventional re-training was modest in this study of community volunteers...
  79. ncbi request reprint Rescuer fatigue: standard versus continuous chest-compression cardiopulmonary resuscitation
    Joseph W Heidenreich
    Department of Emergency Medicine, Scott and White Hospital, 2401 South 31st Street, Temple, TX 76508, USA
    Acad Emerg Med 13:1020-6. 2006
    ..The specific aim of this study was to compare the effects of fatigue on the performance of CCC-CPR and STD-CPR on a manikin model...
  80. ncbi request reprint Hands-only cardiopulmonary resuscitation: is it really dangerous?
    Robert A Berg
    Respir Care 53:855-7. 2008