Research Topics
| Karla M KerlikowskeSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Variability and accuracy in mammographic interpretation using the American College of Radiology Breast Imaging Reporting and Data SystemK Kerlikowske
Department of Epidemiology and Biostatistics, Department of Veterans Affairs, University of California, San Francisco 94121, USA
J Natl Cancer Inst 90:1801-9. 1998....- Are breast density and bone mineral density independent risk factors for breast cancer?Karla Kerlikowske
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA
J Natl Cancer Inst 97:368-74. 2005..We determined whether mammographic breast density and BMD of the hip and spine are correlated and independently associated with breast cancer risk... - Evaluation of abnormal mammography results and palpable breast abnormalitiesKarla Kerlikowske
University of California, San Francisco, General Internal Medicine Section, Department of Veterans Affairs, San Francisco, California 94121, USA
Ann Intern Med 139:274-84. 2003.... - Characteristics associated with recurrence among women with ductal carcinoma in situ treated by lumpectomyKarla Kerlikowske
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA
J Natl Cancer Inst 95:1692-702. 2003..We identified factors associated with recurrence as DCIS versus invasive breast cancer and determined the 5-year absolute risks of recurrence as a function of these factors... - Prognostic characteristics of breast cancer among postmenopausal hormone users in a screened populationKarla Kerlikowske
San Francisco Veterans Affairs Medical Center, General Internal Medicine Section, 111A1, 4150 Clement St, San Francisco, CA 94121, USA
J Clin Oncol 21:4314-21. 2003..We determined the risk of breast cancer and tumor characteristics among current postmenopausal hormone therapy users compared with nonusers, by duration of use... - Breast cancer yield for screening mammographic examinations with recommendation for short-interval follow-upKarla Kerlikowske
Dept of Medicine and Epidemiology and Biostatistics, Univ of California, San Francisco, CA 94121, USA
Radiology 234:684-92. 2005..To compare cancer yield for screening examinations with recommendation for short-interval follow-up after diagnostic imaging work-up versus after screening mammography only... - Differences in screening mammography outcomes among White, Chinese, and Filipino womenKarla Kerlikowske
Department of Epidemiology and Biostatistics, University of California, San Francisco, USA
Arch Intern Med 165:1862-8. 2005..The accuracy of screening mammography among Asian women in the United States has received little attention. We determined whether the accuracy of screening mammography for Chinese and Filipino women differs from that of white women... - How do personal characteristics affect sensitivity and specificity of mammography?Karla Kerlikowske
University of California, San Francisco, San Francisco, CA, USA
Nat Clin Pract Oncol 2:16-7. 2005 - Performance of screening mammography among women with and without a first-degree relative with breast cancerK Kerlikowske
General Internal Medicine Section, 111A1, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
Ann Intern Med 133:855-63. 2000..Although it is recommended that women with a family history of breast cancer begin screening mammography at a younger age than average-risk women, few studies have evaluated the performance of mammography in this group... - Continuing screening mammography in women aged 70 to 79 years: impact on life expectancy and cost-effectivenessK Kerlikowske
Department of Epidemiology and Biostatistics, Department of Veterans Affairs, University of California, San Francisco 94121, USA
JAMA 282:2156-63. 1999..In particular, older women with low bone mineral density (BMD) have a lower risk of breast cancer and may benefit less from continued screening... 
High mammographic breast density is independent predictor of local but not distant recurrence after lumpectomy and radiotherapy for invasive breast cancerCatherine C Park
Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA, USA
Int J Radiat Oncol Biol Phys 73:75-9. 2009..We hypothesized that the MBD might be a predictor of LRR after BCS and RT for invasive breast cancer...
Missed opportunities: family history and behavioral risk factors in breast cancer risk assessment among a multiethnic group of womenLeah S Karliner
Division of General Internal Medicine, Department of Medicine, Medical Effectiveness Research Center for Diverse Populations, University of California, San Francisco, California, USA
J Gen Intern Med 22:308-14. 2007..Clinician's knowledge of a woman's cancer family history (CFH) and counseling about health-related behaviors (HRB) is necessary for appropriate breast cancer care...
Are gatekeeper requirements associated with cancer screening utilization?Kathryn A Phillips
School of Pharmacy, Institute of Health Policy Studies, UCSF Comprehensive Cancer Center, University of California, San Francisco 94143, USA
Health Serv Res 39:153-78. 2004..Our objective was to examine whether gatekeeper requirements are associated with the utilization of cancer screening for breast, cervical, and prostate cancer...- Variation in screening mammography and Papanicolaou smear by primary care physician specialty and gatekeeper plan (United States)David A Haggstrom
San Francisco General Hospital, Division of General Internal Medicine, University of California, San Francisco
Cancer Causes Control 15:883-92. 2004..To assess whether the specialty of a patient's primary care physician or being part of a gatekeeper plan influence breast and cervical cancer screening... - Measurement of breast density with dual X-ray absorptiometry: feasibilityJohn A Shepherd
Department of Radiology, Osteoporosis and Arthritis Research Group, University of California at San Francisco, 94143, USA
Radiology 223:554-7. 2002..998) and with density at mammography (r(adjusted) = 0.83). DXA precision (SD) was 0.5% without and 1.1% with breast repositioning. DXA devices can be used to accurately and precisely estimate breast tissue density... - Screening and prevention of breast cancer in primary careJeffrey A Tice
Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, 1701 Divisadero Street, Suite 554, San Francisco, CA 94143 1732, USA
Prim Care 36:533-58. 2009.... - Longitudinal measurement of clinical mammographic breast density to improve estimation of breast cancer riskKarla Kerlikowske
Department of Epidemiology and Biostatistics, Department of Veterans Affairs, University of California, San Francisco, CA, USA
J Natl Cancer Inst 99:386-95. 2007..Whether a change over time in clinically measured mammographic breast density influences breast cancer risk is unknown... - Novel use of single X-ray absorptiometry for measuring breast densityJohn A Shepherd
Musuloskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94143, USA
Technol Cancer Res Treat 4:173-82. 2005..Using phantoms, BD(SXA) has been shown to have a long-term repeatability of better than 2% for a breast composition range of 0 to 100% fibroglandular density... - Declines in invasive breast cancer and use of postmenopausal hormone therapy in a screening mammography populationKarla Kerlikowske
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA
J Natl Cancer Inst 99:1335-9. 2007.... - Using clinical factors and mammographic breast density to estimate breast cancer risk: development and validation of a new predictive modelJeffrey A Tice
Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, San Francisco, California 94143 1732, USA
Ann Intern Med 148:337-47. 2008..Current models for assessing breast cancer risk are complex and do not include breast density, a strong risk factor for breast cancer that is routinely reported with mammography... - Accuracy of diagnostic mammography at facilities serving vulnerable womenL Elizabeth Goldman
Department of Medicine, University of California San Francisco, San Francisco, CA 94110, USA
Med Care 49:67-75. 2011..Whether accuracy of diagnostic mammography at facilities serving vulnerable women differs from other facilities is unknown... - An assessment of the quality of mammography care at facilities treating medically vulnerable populationsL Elizabeth Goldman
Department of Medicine, University of California, San Francisco, California 94143, USA
Med Care 46:701-8. 2008..Whether mammography facilities that treat vulnerable women demonstrate lower quality of care than other facilities is unknown... - Epidemiology of ductal carcinoma in situKarla Kerlikowske
General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, University of California, San Francisco, 4150 Clement St, 111A1, San Francisco, CA 94121, USA
J Natl Cancer Inst Monogr 2010:139-41. 2010..New information regarding incidence of DCIS and subtypes of DCIS according to frequency of mammography and risk factors could lead to insights into the biology of DCIS... - Long-term prognostic role of functional limitations among women with breast cancerDejana Braithwaite
Helen Diller Family Comprehensive Cancer Center and the Department of Epidemiology and Biostatistics, University of California, San Francisco, 185 Berry St, Ste 5700, San Francisco, CA 94107, USA
J Natl Cancer Inst 102:1468-77. 2010..The long-term prognostic role of functional limitations among women with breast cancer is poorly understood... - Breast cancer risk by breast density, menopause, and postmenopausal hormone therapy useKarla Kerlikowske
General Internal Medicine Section, University of California, San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, CA, USA
J Clin Oncol 28:3830-7. 2010..We determined whether the association between breast density and breast cancer risk and cancer severity differs according to menopausal status and postmenopausal hormone therapy (HT) use... - Obesity, mammography use and accuracy, and advanced breast cancer riskKarla Kerlikowske
Department of Epidemiology and Biostatistics, General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA 94121, USA
J Natl Cancer Inst 100:1724-33. 2008.... - Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosisKarla Kerlikowske
University of California, San Francisco, CA 94121, USA corrected
J Natl Cancer Inst 102:627-37. 2010..Studies have failed to identify characteristics of women who have been diagnosed with ductal carcinoma in situ (DCIS) and have a high or low risk of subsequent invasive cancer... - Positive predictive value of specific mammographic findings according to reader and patient variablesAruna Venkatesan
School of Medicine, University of California, San Francisco, 513 Parnassus Ave, Room S 245, San Francisco, CA 94143 0454, USA
Radiology 250:648-57. 2009.... - Ethnic disparities in breast cancerLeah S Karliner
University of California, San Francisco, and Medical Effectiveness Research Center for Diverse Populations, San Francisco, CA, USA
Womens Health (Lond Engl) 3:679-88. 2007..This review will examine what is known regarding ethnic differences in all of these areas, what questions remain, and where researchers and policy makers should focus their future efforts... - Trends in colonoscopy for colorectal cancer screeningKathryn A Phillips
University of California, San Francisco, CA 94143, USA
Med Care 45:160-7. 2007..A major health priority is to increase colorectal cancer screening, and colonoscopy has become an increasingly important method of screening. The Medicare program began coverage for colonoscopy for average risk individuals in 2001... - Clinical comparison of a novel breast DXA technique to mammographic densityJohn A Shepherd
Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, California 94143, USA
Med Phys 33:1490-8. 2006..We conclude that breast composition can be precisely evaluated and assessed with clinical DXA densitometers at a lower dose than with mammographic breast density methods... - Detection of ductal carcinoma in situ in women undergoing screening mammographyVirginia L Ernster
Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, USA
J Natl Cancer Inst 94:1546-54. 2002..Given uncertainty about the natural history of DCIS, the clinical significance of screen-detected DCIS needs further investigation... - Accuracy of mammographic breast density analysis: results of formal operator trainingSven Prevrhal
Department of Radiology, University of California, San Francisco, California 94143-1250, USA
Cancer Epidemiol Biomarkers Prev 11:1389-93. 2002.... - Mammographic breast density and family history of breast cancerElad Ziv
Division of General Internal Medicine and Department of Medicine, University of California, San Francisco, USA
J Natl Cancer Inst 95:556-8. 2003..37, 95% confidence interval [CI] = 0.96 to 1.89; BI-RADS 3, OR = 1.70, 95% CI = 1.19 to 2.40; BI-RADS 4, OR = 1.70, 95% CI = 1.05 to 2.71). Thus, the genetic factors that determine breast density may determine breast cancer risk... - Comparison of screening mammography in the United States and the United kingdomRebecca Smith-Bindman
Department of Radiology, University of California, San Francisco 94115, USA
JAMA 290:2129-37. 2003..Screening mammography differs between the United States and the United Kingdom; a direct comparison may suggest methods to improve the practice... - Protective association of aspirin/NSAIDs and esophageal cancer: a systematic review and meta-analysisDouglas A Corley
Northern California Kaiser Division of Research, Department of Medicine, University of California San Francisco, 2238 Geary Boulevard, GI 2 West, San Francisco, CA 94115, USA
Gastroenterology 124:47-56. 2003..We performed a systematic review with meta-analysis of observational studies evaluating the association of aspirin/nonsteroidal anti-inflammatory drug (NSAID) use and esophageal cancer... - Mammographic density and estrogen receptor status of breast cancerElad Ziv
Department of Medicine, University of California at San Francisco, 1635 Divisadero Street, Suite 600, San Francisco, CA 04115, USA
Cancer Epidemiol Biomarkers Prev 13:2090-5. 2004..We determined if mammographic density is associated more strongly with ER-positive breast cancer than with ER-negative breast cancer... - Physician predictors of mammographic accuracyRebecca Smith-Bindman
Department of Radiology, University of California, San Francisco, 1600 Divisadero St, San Francisco, CA 94115, USA
J Natl Cancer Inst 97:358-67. 2005..The association between physician experience and the accuracy of screening mammography in community practice is not well studied. We identified characteristics of U.S. physicians associated with the accuracy of screening mammography... - Comparing the performance of mammography screening in the USA and the UKRebecca Smith-Bindman
Department of Radiology, University of California, San Francisco, CA 94115, USA
J Med Screen 12:50-4. 2005..Efforts to improve mammographic screening in the USA should target lowering the recall rate without reducing the cancer detection rate... - Mammographic breast density and the Gail model for breast cancer risk prediction in a screening populationJeffrey A Tice
Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA 94143 1732, USA
Breast Cancer Res Treat 94:115-22. 2005..Although the current standard, the Gail model, is well calibrated in populations, it performs poorly for individuals. Mammographic breast density (BD) may improve the predictive accuracy of the Gail model... - Can Medicare billing claims data be used to assess mammography utilization among women ages 65 and older?Rebecca Smith-Bindman
Department of Radiology, University of California, San Francisco, CA 94115, USA
Med Care 44:463-70. 2006..Medicare data may be a useful source for determining the utilization of mammography among elderly women, but the accuracy of these data has not been established... - Does utilization of screening mammography explain racial and ethnic differences in breast cancer?Rebecca Smith-Bindman
University of California and San Francisco Veterans Affairs Medical Center, San Francisco, California 94115, USA
Ann Intern Med 144:541-53. 2006..Reasons for persistent differences in breast cancer mortality rates among various racial and ethnic groups have been difficult to ascertain... - Breast cancer risk reduction options: awareness, discussion, and use among women from four ethnic groupsCelia Patricia Kaplan
Division of General Internal Medicine, Department of Medicine, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA 94143 0856, USA
Cancer Epidemiol Biomarkers Prev 15:162-6. 2006..With recent advances in breast cancer risk reduction practices, it is increasingly important to assess both the breadth of and disparities in use across different racial/ethnic groups... - Changes in invasive breast cancer and ductal carcinoma in situ rates in relation to the decline in hormone therapy useGhada N Farhat
San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, CA, USA
J Clin Oncol 28:5140-6. 2010..To assess trends in invasive breast cancer and ductal carcinoma in situ (DCIS) incidence in association with changes in hormone therapy (HT) use in regular mammography screeners... - Factors affecting participation in a breast cancer risk reduction telephone survey among women from four racial/ethnic groupsGenevieve Des Jarlais
Department of Medicine, Division of General Internal Medicine, Medical Effectiveness Research Center, University of California, 3333 California Street, Suite 335, San Francisco, CA 94143-0856, USA
Prev Med 41:720-7. 2005..47, CI 0.26-0.86), Blacks (OR = 0.29, CI 0.11-0.78), and Latinas (OR = 0.51, CI 0.28-0.94). CONCLUSIONS: Results suggest minorities' participation in health behavior research does not match Whites' and should be enhanced... - Single x-ray absorptiometry method for the quantitative mammographic measure of fibroglandular tissue volumeSerghei Malkov
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California 94143, USA
Med Phys 36:5525-36. 2009.... - Association between breast density and subsequent breast cancer following treatment for ductal carcinoma in situE Shelley Hwang
Department of Surgery, University of California, San Francisco Cancer Center, 1600 Divisadero Avenue, B606 San Francisco, CA 94115, USA
Cancer Epidemiol Biomarkers Prev 16:2587-93. 2007..All subjects had an American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) breast density measure recorded prior to diagnosis... - Compositional breast imaging using a dual-energy mammography protocolAurelie D Laidevant
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143, USA
Med Phys 37:164-74. 2010..This article describes a novel approach to dual-energy mammography, full-field digital compositional mammography (FFDCM), which can independently image the three compositional components of breast tissue: water, lipid, and protein... - Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumorsMona L Gauthier
Department of Pathology, University of California, San Francisco, CA 94143, USA
Cancer Cell 12:479-91. 2007..Assessment of these biomarkers in DCIS begins to allow prediction of tumor formation years before it actually occurs... - Patterns of chromosomal alterations in breast ductal carcinoma in situE Shelley Hwang
Department of Surgery, University of California San Francisco, San Francisco, California 94115, USA
Clin Cancer Res 10:5160-7. 2004..Genomic changes specific to pure DCIS versus invasive cancer, as well as alterations unique to individual DCIS subtypes, have not been fully defined... - Physician workload in mammographyRebecca Smith-Bindman
Department of Radiology, University of California, San Francisco, China Basin Landing, 185 Berry St, STE 350, Lobby 7, Campus Box 0946, San Francisco, CA 94107, USA
AJR Am J Roentgenol 190:526-32. 2008..The purpose of our study was to estimate per-physician annual volumes of mammography interpretation... - Risk of cervical cancer associated with extending the interval between cervical-cancer screeningsGeorge F Sawaya
Department of Obstetrics, Gynecology, and Reproductive Sciences, Department of Veterans Affairs and University of California, San Francisco, San Francisco, USA
N Engl J Med 349:1501-9. 2003....
Research Grants
- San Francisco Mammography Registry-A Research SourceKarla Kerlikowske; Fiscal Year: 2007....