Richard A Kerber

Summary

Affiliation: University of Louisville
Country: USA

Publications

  1. pmc A genome-wide study replicates linkage of 3p22-24 to extreme longevity in humans and identifies possible additional loci
    Richard A Kerber
    Department of Oncological Sciences, University of Utah, Salt Lake City, Utah, United States of America
    PLoS ONE 7:e34746. 2012
  2. pmc Gene expression profiles associated with aging and mortality in humans
    Richard A Kerber
    Department of Oncological Sciences, 2000 Circle of Hope, Salt Lake City, UT 84112 5550, USA
    Aging Cell 8:239-50. 2009
  3. pmc Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a large family with excess colorectal cancer
    Deborah W Neklason
    Department of Oncological Sciences, University of Utah, Salt Lake City, Utah, USA
    J Med Genet 47:692-9. 2010
  4. doi request reprint Quantification of the familial contribution to müllerian anomalies
    Ahmad O Hammoud
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Obstet Gynecol 111:378-84. 2008
  5. pmc Colonic adenoma risk in familial colorectal cancer--a study of six extended kindreds
    Deborah W Neklason
    Huntsman Cancer Institute, Salt Lake City, Utah 84112 5550, USA
    Am J Gastroenterol 103:2577-84. 2008
  6. pmc American founder mutation for attenuated familial adenomatous polyposis
    Deborah W Neklason
    Department of Oncological Sciences, University of Utah, Salt Lake City, Utah 84112 5550, USA
    Clin Gastroenterol Hepatol 6:46-52. 2008
  7. pmc Longevity and correlated frailty in multigenerational families
    Gilda Garibotti
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA
    J Gerontol A Biol Sci Med Sci 61:1253-61. 2006
  8. doi request reprint Estimating recurrence of spontaneous preterm delivery
    MICHAEL S ESPLIN
    University of Utah Health Sciences Center, Department of Obstetrics and Gynecology, Salt Lake City, Utah 84132, USA
    Obstet Gynecol 112:516-23. 2008
  9. pmc Mitochondrial genomic analysis of late onset Alzheimer's disease reveals protective haplogroups H6A1A/H6A1B: the Cache County Study on Memory in Aging
    Perry G Ridge
    Department of Biology, Brigham Young University, Provo, Utah, USA
    PLoS ONE 7:e45134. 2012
  10. ncbi request reprint Association between telomere length in blood and mortality in people aged 60 years or older
    Richard M Cawthon
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Lancet 361:393-5. 2003

Detail Information

Publications20

  1. pmc A genome-wide study replicates linkage of 3p22-24 to extreme longevity in humans and identifies possible additional loci
    Richard A Kerber
    Department of Oncological Sciences, University of Utah, Salt Lake City, Utah, United States of America
    PLoS ONE 7:e34746. 2012
    ..Although there is abundant evidence that human longevity is heritable, efforts to map loci responsible for variation in human lifespan have had limited success...
  2. pmc Gene expression profiles associated with aging and mortality in humans
    Richard A Kerber
    Department of Oncological Sciences, 2000 Circle of Hope, Salt Lake City, UT 84112 5550, USA
    Aging Cell 8:239-50. 2009
    ..These observations may lead to new insights regarding the genetic contribution to exceptional longevity...
  3. pmc Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a large family with excess colorectal cancer
    Deborah W Neklason
    Department of Oncological Sciences, University of Utah, Salt Lake City, Utah, USA
    J Med Genet 47:692-9. 2010
    ..Fewer than 5% of colon cancers arise in the presence of a clear hereditary cancer condition; however, current estimates suggest that an additional 15-25% of colorectal cancers arise on the basis of unknown inherited factors...
  4. doi request reprint Quantification of the familial contribution to müllerian anomalies
    Ahmad O Hammoud
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Obstet Gynecol 111:378-84. 2008
    ..To quantify the familial contribution to müllerian anomalies and determine a possible inheritance pattern...
  5. pmc Colonic adenoma risk in familial colorectal cancer--a study of six extended kindreds
    Deborah W Neklason
    Huntsman Cancer Institute, Salt Lake City, Utah 84112 5550, USA
    Am J Gastroenterol 103:2577-84. 2008
    ..This issue is clinically relevant since several medical societies currently recommend earlier and more rigorous colorectal screening for individuals with a strong family history of CRC...
  6. pmc American founder mutation for attenuated familial adenomatous polyposis
    Deborah W Neklason
    Department of Oncological Sciences, University of Utah, Salt Lake City, Utah 84112 5550, USA
    Clin Gastroenterol Hepatol 6:46-52. 2008
    ....
  7. pmc Longevity and correlated frailty in multigenerational families
    Gilda Garibotti
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA
    J Gerontol A Biol Sci Med Sci 61:1253-61. 2006
    ..143 and 0.186, respectively. Through simulations, we also show a greater reduction in the bias of parameter estimates for fixed covariates through the use of the correlated frailty model...
  8. doi request reprint Estimating recurrence of spontaneous preterm delivery
    MICHAEL S ESPLIN
    University of Utah Health Sciences Center, Department of Obstetrics and Gynecology, Salt Lake City, Utah 84132, USA
    Obstet Gynecol 112:516-23. 2008
    ....
  9. pmc Mitochondrial genomic analysis of late onset Alzheimer's disease reveals protective haplogroups H6A1A/H6A1B: the Cache County Study on Memory in Aging
    Perry G Ridge
    Department of Biology, Brigham Young University, Provo, Utah, USA
    PLoS ONE 7:e45134. 2012
    ..paternal inheritance, a pattern consistent with mitochondrial inheritance. The role of specific mitochondrial DNA (mtDNA) variants and haplogroups in AD risk is uncertain...
  10. ncbi request reprint Association between telomere length in blood and mortality in people aged 60 years or older
    Richard M Cawthon
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Lancet 361:393-5. 2003
    ..0079), and an 8.54-fold higher mortality rate from infectious disease (1.52-47.9, p=0.015). These results lend support to the hypothesis that telomere shortening in human beings contributes to mortality in many age-related diseases...
  11. ncbi request reprint The impact of a growing minority population on identification of duplicate records in an enterprise data warehouse
    Scott L DuVall
    Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA
    Stud Health Technol Inform 160:1122-6. 2010
    ....
  12. doi request reprint Familial predisposition to developmental dysplasia of the hip
    David A Stevenson
    Department of Pediatrics, University of Utah, Salt Lake City, UT 84132, USA
    J Pediatr Orthop 29:463-6. 2009
    ..The purpose of this study is to assess the degree of relationship between individuals with DDH...
  13. ncbi request reprint Frequency of familial colon cancer and hereditary nonpolyposis colorectal cancer (Lynch syndrome) in a large population database
    Richard A Kerber
    Department of Oncological Sciences, University of Utah, School of Medicine, USA
    Fam Cancer 4:239-44. 2005
    ....
  14. ncbi request reprint A cohort study of cancer risk in relation to family histories of cancer in the Utah population database
    Richard A Kerber
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 5550, USA
    Cancer 103:1906-15. 2005
    ..It is well known that genetic variability affects the risk of many cancers, but details of the patterning of inherited cancer risk across different sites and age groups still are not well quantified...
  15. pmc Common familial colorectal cancer linked to chromosome 7q31: a genome-wide analysis
    Deborah W Neklason
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 5550, USA
    Cancer Res 68:8993-7. 2008
    ..9; P = 0.02). No known familial cancer genes reside in the 7q31 locus, and thus the identified region may contain a novel susceptibility gene responsible for common familial colorectal cancer...
  16. ncbi request reprint Familial aggregation of juvenile idiopathic arthritis
    Sampath Prahalad
    University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Arthritis Rheum 50:4022-7. 2004
    ..To estimate the degree of familial aggregation of juvenile idiopathic arthritis (JIA), determine whether the aggregation of JIA and the aggregation of type 1 diabetes mellitus (type 1 DM) overlap, and identify multiplex JIA pedigrees...
  17. doi request reprint Inflammatory bowel disease aggregation in Utah kindreds
    Stephen L Guthery
    Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Utah School of Medicine and Primary Children s Medical Center, Salt Lake City, Utah 84113, USA
    Inflamm Bowel Dis 17:823-30. 2011
    ..Kindred-specific genetic variants that cause IBD may be a source of "missing heritability." Given that they have been previously difficult to identify, we sought to identify high-risk IBD kindreds...
  18. doi request reprint Extending the Fellegi-Sunter probabilistic record linkage method for approximate field comparators
    Scott L DuVall
    Department of Biomedical Informatics, University of Utah, Utah, USA
    J Biomed Inform 43:24-30. 2010
    ..Given the ubiquity of linkage in both clinical and research settings, the incremental improvement of the extension has the potential to make a considerable impact...
  19. pmc Design considerations in a sib-pair study of linkage for susceptibility loci in cancer
    Richard A Kerber
    Population Sciences Program, Hunstman Cancer Institute, Salt Lake City, UT, USA
    BMC Med Genet 9:64. 2008
    ..However, the sibpair design is still valuable because it requires few assumptions other than acceptably high penetrance to identify genetic loci...
  20. ncbi request reprint Genetic testing and phenotype in a large kindred with attenuated familial adenomatous polyposis
    Randall W Burt
    Department of Medicine, University of Utah, Salt Lake City, USA
    Gastroenterology 127:444-51. 2004
    ..An attenuated form of familial adenomatous polyposis has been described, but the phenotype remains poorly understood...