C L Kepley

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. ncbi Multiple defects in Fc epsilon RI signaling in Syk-deficient nonreleaser basophils and IL-3-induced recovery of Syk expression and secretion
    C L Kepley
    Department of Pathology, University of New Mexico, Albuquerque, NM 87131, USA
    J Immunol 165:5913-20. 2000
  2. ncbi Immunohistochemical detection of human basophils in postmortem cases of fatal asthma
    C L Kepley
    Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
    Am J Respir Crit Care Med 164:1053-8. 2001
  3. ncbi Regulation of the very late antigen-4-mediated adhesive activity of normal and nonreleaser basophils: roles for Src, Syk, and phosphatidylinositol 3-kinase
    R P Andrews
    Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    J Leukoc Biol 70:776-82. 2001
  4. ncbi Immunologically mediated signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human FcvarepsilonR1 signaling pathway
    J M Oliver
    University of New Mexico, School of Medicine, Department of Pathology, Albuquerque, NM 87131, USA
    Immunopharmacology 48:269-81. 2000
  5. ncbi The identification and characterization of umbilical cord blood-derived human basophils
    C L Kepley
    Department of Pathology, Asthma Research Center, Virginia Commonwealth University Medical College of Virginia, Richmond, USA
    J Leukoc Biol 64:474-83. 1998
  6. ncbi Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation
    A Chigaev
    Department of Pathology and Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
    J Biol Chem 276:48670-8. 2001

Collaborators

Detail Information

Publications6

  1. ncbi Multiple defects in Fc epsilon RI signaling in Syk-deficient nonreleaser basophils and IL-3-induced recovery of Syk expression and secretion
    C L Kepley
    Department of Pathology, University of New Mexico, Albuquerque, NM 87131, USA
    J Immunol 165:5913-20. 2000
    ....
  2. ncbi Immunohistochemical detection of human basophils in postmortem cases of fatal asthma
    C L Kepley
    Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
    Am J Respir Crit Care Med 164:1053-8. 2001
    ..In summary, basophil infiltration was significantly increased in lungs from individuals who died from asthma, supporting the hypothesis that basophils are involved in the pathogenesis of FA...
  3. ncbi Regulation of the very late antigen-4-mediated adhesive activity of normal and nonreleaser basophils: roles for Src, Syk, and phosphatidylinositol 3-kinase
    R P Andrews
    Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    J Leukoc Biol 70:776-82. 2001
    ..Both Src and Syk-regulated components of adhesion may be impaired in nonreleaser basophils...
  4. ncbi Immunologically mediated signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human FcvarepsilonR1 signaling pathway
    J M Oliver
    University of New Mexico, School of Medicine, Department of Pathology, Albuquerque, NM 87131, USA
    Immunopharmacology 48:269-81. 2000
    ..These strategies may form the basis for new therapies for allergic inflammation...
  5. ncbi The identification and characterization of umbilical cord blood-derived human basophils
    C L Kepley
    Department of Pathology, Asthma Research Center, Virginia Commonwealth University Medical College of Virginia, Richmond, USA
    J Leukoc Biol 64:474-83. 1998
    ..These studies establish cord blood as an accessible source from which basophil-like cells can be developed to examine Fc epsilonRI-mediated signal transduction...
  6. ncbi Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation
    A Chigaev
    Department of Pathology and Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
    J Biol Chem 276:48670-8. 2001
    ..It appears that the physiologically active state of the alpha(4)-integrin, determined by inside-out signaling, has similar affinity in several cell types...