Cynthia J Kenyon

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing
    Cynthia Kenyon
    University of California, San Francisco, CA 94158, USA
    Philos Trans R Soc Lond B Biol Sci 366:9-16. 2011
  2. pmc Could a hormone point the way to life extension?
    Cynthia Kenyon
    is at the University of California, San Francisco, United States
    elife 1:e00286. 2012
  3. doi request reprint The genetics of ageing
    Cynthia J Kenyon
    Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California 94158, USA
    Nature 464:504-12. 2010
  4. doi request reprint A pathway that links reproductive status to lifespan in Caenorhabditis elegans
    Cynthia Kenyon
    Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA
    Ann N Y Acad Sci 1204:156-62. 2010

Detail Information

Publications4

  1. pmc The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing
    Cynthia Kenyon
    University of California, San Francisco, CA 94158, USA
    Philos Trans R Soc Lond B Biol Sci 366:9-16. 2011
    ..This life-extension pathway, the first to be defined, was discovered through genetic studies in the small roundworm Caenorhabditis elegans. This discovery is described here...
  2. pmc Could a hormone point the way to life extension?
    Cynthia Kenyon
    is at the University of California, San Francisco, United States
    elife 1:e00286. 2012
    ..Mice that have been genetically modified to produce high levels of fibroblast growth factor-21 live longer than mice with normal levels of this hormone...
  3. doi request reprint The genetics of ageing
    Cynthia J Kenyon
    Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California 94158, USA
    Nature 464:504-12. 2010
    ..Which genes can extend lifespan? Can we augment their activities and live even longer? After centuries of wistful poetry and wild imagination, we are now getting answers, often unexpected ones, to these fundamental questions...
  4. doi request reprint A pathway that links reproductive status to lifespan in Caenorhabditis elegans
    Cynthia Kenyon
    Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA
    Ann N Y Acad Sci 1204:156-62. 2010
    ....

Research Grants37

  1. ANTERO POSTERIOR PATTERN FORMATION IN C ELEGANS
    Cynthia Kenyon; Fiscal Year: 2001
    ..Together these studies should help to define the molecular mechanisms that regulate and execute these migrations. ..
  2. GENETIC ANALYSIS OF AGING IN C ELEGANS
    Cynthia Kenyon; Fiscal Year: 2003
    ..Understanding this pathway in detail will ultimately answer the two most important questions in the aging field: how the aging process itself takes place, and how it can be regulated by endocrine signaling. ..
  3. Regulation of aging by germline stem cells in C. elegans
    Cynthia Kenyon; Fiscal Year: 2006
    ..In addition, our findings may yield insights into the ways that stem cells can influence endocrine signaling in vertebrates. ..
  4. Lifespan regulation by the DAF-12 nuclear hormone receptor in C. elegans
    Cynthia Kenyon; Fiscal Year: 2007
    ..This study, which takes place within a single, genetically-tractable, species, provides a fantastic opportunity to identify mechanisms that can produce extreme differences in lifespan ..
  5. Signals from the reproductive system that regulate aging in C. elegans
    Cynthia J Kenyon; Fiscal Year: 2010
    ..We propose to learn how signals from the reproductive system influence lifespan, in hopes of finding new ways to increase youthfulness and health, and to combat age-related disease, in humans. ..
  6. GENETIC ANALYSIS OF PATTERN FORMATION IN CAENORHABDITIS
    Cynthia Kenyon; Fiscal Year: 1993
    ....
  7. Lifespan regulation by the DAF-12 nuclear hormone receptor in C. elegans
    Cynthia J Kenyon; Fiscal Year: 2010
    ..This study, which takes place within a single, genetically-tractable, species, provides a fantastic opportunity to identify mechanisms that can produce extreme differences in lifespan ..