K C Kent Lloyd

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi A knockout mouse resource for the biomedical research community
    K C Kent Lloyd
    Mouse Biology Program, University of California Davis, Davis, California, USA
    Ann N Y Acad Sci 1245:24-6. 2011
  2. ncbi Rederivation of transgenic mice from iPS cells derived from frozen tissue
    Angus Yiu Fai Lee
    Mouse Biology Program, Center for Comparative Medicine, School of Veterinary Medicine, University of California, 2795 2nd Street, Suite 400, Davis, CA 95618, USA
    Transgenic Res 20:167-75. 2011
  3. ncbi The scientific component of residency training
    K C Kent Lloyd
    School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Vet Med Educ 35:53-7. 2008
  4. ncbi Acid inhibition by intestinal nutrients mediated by CCK-A receptors but not plasma CCK
    K C Lloyd
    Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis 95616, USA
    Am J Physiol Gastrointest Liver Physiol 281:G924-30. 2001
  5. ncbi Behavioral characteristics of a nervous system-specific erbB4 knock-out mouse
    Mari S Golub
    Department of Internal Medicine, CNPRC, University of California, Davis, CA 95616, USA
    Behav Brain Res 153:159-70. 2004
  6. ncbi Movement disorders in the Hfe knockout mouse
    Mari S Golub
    Murine Behavior Assessment Laboratory, Mutant Mouse Regional Resource Center, University of California, Davis Davis, California 95616, USA
    Nutr Neurosci 8:239-44. 2005
  7. ncbi EGF and TGF-alpha supplementation enhances development of cloned mouse embryos
    Tedla D Dadi
    Center for Comparative Medicine, School of Veterinary, University of California Davis, Davis, California 95616, USA
    Cloning Stem Cells 9:315-26. 2007
  8. ncbi Apolipoprotein A-IV is involved in detection of lipid in the rat intestine
    K L Whited
    1321 Haring Hall, Vet Med: APC, UC Davis School of Veterinary Medicine, Davis, CA 95616, USA
    J Physiol 569:949-58. 2005
  9. ncbi Development of mouse embryos after immunoneutralization of mitogenic growth factors mimics that of cloned embryos
    Tedla D Dadi
    Mouse Biology Program, Center for Comparative Medicine, School of Veterinary Medicine, University of California, Davis, California, USA
    Comp Med 56:188-95. 2006
  10. ncbi Expression levels of EGF, TGF-alpha, and EGF-R are significantly reduced in pre-implantation cloned mouse embryos
    Tedla D Dadi
    Center for Comparative Medicine, School of Veterinary Medicine, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA
    Cloning Stem Cells 6:267-83. 2004

Research Grants

  1. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC LLOYD; Fiscal Year: 2007
  2. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC KENT LLOYD; Fiscal Year: 2010
  3. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC LLOYD; Fiscal Year: 2009
  4. UCD KOMP Project Repository
    KC LLOYD; Fiscal Year: 2007
  5. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC LLOYD; Fiscal Year: 2005
  6. ADVANCED RESEARCH (YEAR) PROGRAM FOR VET STUDENTS
    KC LLOYD; Fiscal Year: 2007
  7. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC LLOYD; Fiscal Year: 2006
  8. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC KENT LLOYD; Fiscal Year: 2010

Collaborators

  • Tedla D Dadi
  • John D Biggers
  • M S Golub
  • H E Raybould
  • T E Solomon
  • A S Kopin
  • David W Hird
  • Marc B Schenker
  • N Binart
  • A Roses
  • Kay Uwe Wagner
  • Eva Anton
  • Frank Jones
  • T R Insel
  • Maja Bucan
  • KC LLOYD
  • KC KENT LLOYD
  • K C Kent Lloyd
  • Ming Wen Li
  • K L Whited
  • Ming-Wen Li
  • Angus Yiu Fai Lee
  • Stephen M Griffey
  • Mehmet Toner
  • Ming W Li
  • H T Ghashghaei
  • Lynda McGinnis
  • Christopher P Austin
  • Weiwen Long
  • K C Lloyd
  • Brandon J Willis
  • Jimmy L Spearow
  • Heidi Y Elmoazzen
  • Markus H Schwab
  • Ralf Schmid
  • Janet Weber
  • David D Eisenstat
  • D Thao
  • Cary Lai
  • Larysa Pevny
  • P Tso
  • D Lu
  • Andras Nagy
  • Mark W Moore
  • Francis Stewart
  • Philippe Soriano
  • Harald von Melchner
  • Alexandra Joyner
  • Francis S Collins
  • Thomas F Vogt
  • William F Dove
  • Mario Capecchi
  • Janan T Eppig
  • James F Battey
  • David J Stewart
  • Nathaniel Heintz
  • Geoffrey Duyk
  • Jan Witkowski
  • Bruce Stillman
  • Beverly H Koller
  • Brian Seed
  • Inder M Verma
  • Allan Bradley
  • Arthur T Sands
  • Lyuba Varticovski
  • Harold Varmus
  • Jonathan D Pollock
  • Jay Snoddy
  • Brian Zambrowicz
  • Richard P Woychik
  • Geoff Hicks
  • William C Skarnes
  • Wolfgang Wurst
  • George D Yancopoulos
  • Susan Dymecki
  • Terry Magnuson
  • Franziska B Grieder
  • Stephen G Young
  • Jonathan M Shillingford
  • Liben Zhu
  • Joel Lawitts
  • Lothar Hennighausen
  • J Wang

Detail Information

Publications21

  1. ncbi A knockout mouse resource for the biomedical research community
    K C Kent Lloyd
    Mouse Biology Program, University of California Davis, Davis, California, USA
    Ann N Y Acad Sci 1245:24-6. 2011
    ..The Knockout Mouse Project (KOMP) Repository archives and distributes vectors, embryonic stem cell clones, frozen germplasm, and live mutant mice for 8,500 knockout genes. Here, we describe the creation and functions of the KOMP Repository...
  2. ncbi Rederivation of transgenic mice from iPS cells derived from frozen tissue
    Angus Yiu Fai Lee
    Mouse Biology Program, Center for Comparative Medicine, School of Veterinary Medicine, University of California, 2795 2nd Street, Suite 400, Davis, CA 95618, USA
    Transgenic Res 20:167-75. 2011
    ....
  3. ncbi The scientific component of residency training
    K C Kent Lloyd
    School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Vet Med Educ 35:53-7. 2008
    ....
  4. ncbi Acid inhibition by intestinal nutrients mediated by CCK-A receptors but not plasma CCK
    K C Lloyd
    Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis 95616, USA
    Am J Physiol Gastrointest Liver Physiol 281:G924-30. 2001
    ..5 +/- 3.6 pM), lipid (12.3 +/- 2.2 pM), and dextrose (11.9 +/- 1.5 pM). Lipid and carbohydrate inhibit acid secretion by activating CCK-A receptors but not by altering plasma CCK concentrations...
  5. ncbi Behavioral characteristics of a nervous system-specific erbB4 knock-out mouse
    Mari S Golub
    Department of Internal Medicine, CNPRC, University of California, Davis, CA 95616, USA
    Behav Brain Res 153:159-70. 2004
    ..These findings were interpreted based on more detailed analysis of the behavioral data and considerations of the complex nature and multiple roles of the neuregulin/erbB4 system in the nervous system...
  6. ncbi Movement disorders in the Hfe knockout mouse
    Mari S Golub
    Murine Behavior Assessment Laboratory, Mutant Mouse Regional Resource Center, University of California, Davis Davis, California 95616, USA
    Nutr Neurosci 8:239-44. 2005
    ..Iron accumulation in brain was not detected by histopathology. These data suggest that a motor syndrome may be associated with HHH that could be further understood through the Hfe(-/-) mouse model...
  7. ncbi EGF and TGF-alpha supplementation enhances development of cloned mouse embryos
    Tedla D Dadi
    Center for Comparative Medicine, School of Veterinary, University of California Davis, Davis, California 95616, USA
    Cloning Stem Cells 9:315-26. 2007
    ..These results demonstrate that mitogenic growth factors significantly enhance survival and promote the preimplantation development of cloned mouse embryos...
  8. ncbi Apolipoprotein A-IV is involved in detection of lipid in the rat intestine
    K L Whited
    1321 Haring Hall, Vet Med: APC, UC Davis School of Veterinary Medicine, Davis, CA 95616, USA
    J Physiol 569:949-58. 2005
    ..We conclude that activation of the vagal afferent pathway and inhibition of gastric function in response to dietary lipid is partly dependent upon apo A-IV...
  9. ncbi Development of mouse embryos after immunoneutralization of mitogenic growth factors mimics that of cloned embryos
    Tedla D Dadi
    Mouse Biology Program, Center for Comparative Medicine, School of Veterinary Medicine, University of California, Davis, California, USA
    Comp Med 56:188-95. 2006
    ....
  10. ncbi Expression levels of EGF, TGF-alpha, and EGF-R are significantly reduced in pre-implantation cloned mouse embryos
    Tedla D Dadi
    Center for Comparative Medicine, School of Veterinary Medicine, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA
    Cloning Stem Cells 6:267-83. 2004
  11. ncbi Phenotypic analysis of C57BL/6J and FVB/NJ mice generated using evaporatively dried spermatozoa
    Ming Wen Li
    Center for Comparative Medicine, School of Veterinary Medicine, University of California, Davis, CA, USA
    Comp Med 57:469-75. 2007
    ..Therefore, spermatozoa from inbred mouse strains C57BL/6J and FVB/NJ can be preserved successfully after evaporative drying and frozen storage at -80 degrees C...
  12. ncbi Assessment of three generations of mice derived by ICSI using freeze-dried sperm
    Ming Wen Li
    Mouse Biology Program, School of Veterinary Medicine, University of California, Davis, California, USA
    Zygote 17:239-51. 2009
    ....
  13. ncbi Decreased growth factor expression through RNA interference inhibits development of mouse preimplantation embryos
    Tedla D Dadi
    Mouse Biology Program, Center for Comparative Medicine, School of Veterinary Medicine, University of California, Davis, California, USA
    Comp Med 59:331-8. 2009
    ..These results support our hypothesis that EGF and TGFalpha are crucial for embryo survival and development. Further, dysregulated expression of growth factors is associated with poor development of cloned mouse embryos...
  14. ncbi Intracytoplasmic sperm injection (ICSI) enables rescue of valuable mutant mouse strains
    Ming-Wen Li
    Murine Targeted Genomics Laboratory, Mouse Biology Program, Center for Comparative Medicine, University of California, Davis, California, USA
    Comp Med 53:265-9. 2003
    ....
  15. ncbi Targeted disruption of the murine CCK1 receptor gene reduces intestinal lipid-induced feedback inhibition of gastric function
    K L Whited
    Department of Anatomy, Physiology, and Cell Biology, School of Vetinary Medicine, University of California, Davis School of Veterinary Medicine, Davis, CA 95616, USA
    Am J Physiol Gastrointest Liver Physiol 291:G156-62. 2006
    ..Thus, despite a relatively normal phenotype, intestinal feedback in response to lipid is severely impaired in these mice...
  16. ncbi Public health education at the University of California, Davis: past, present, and future programs
    David W Hird
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Vet Med Educ 35:219-24. 2008
    ....
  17. ncbi Long-term storage of mouse spermatozoa after evaporative drying
    Ming W Li
    School of Veterinary Medicine, Center for Comparative Medicine, University of California, Davis, CA 95616, USA
    Reproduction 133:919-29. 2007
    ..The possibility that the storage temperature must be less than the glass transition temperature is discussed...
  18. ncbi Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain
    E S Anton
    UNC Neuroscience Center and the Department of Cell and Molecular Physiology, The University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Nat Neurosci 7:1319-28. 2004
    ..These findings suggest that ErbB4 activation helps to regulate the organization of neural chains that form the rostral migratory stream and influences the differentiation of olfactory interneuronal precursors...
  19. ncbi Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5
    Weiwen Long
    Department of Structural and Cellular Biology, Tulane Cancer Center, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, Louisiana 70112 2699, USA
    Development 130:5257-68. 2003
    ....
  20. ncbi The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone
    H T Ghashghaei
    University of North Carolina Neuroscience Center and the Department of Cell and Molecular Physiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Proc Natl Acad Sci U S A 103:1930-5. 2006
    ..Furthermore, these studies identify NRG2 as a factor capable of promoting SVZ proliferation, leading to the formation of new neurons in vivo...
  21. ncbi The knockout mouse project
    Christopher P Austin
    National Human Genome Research Institute, National Institutes of Health, Building 31, Room 4B09, 31 Center Drive, Bethesda, Maryland 20892, USA
    Nat Genet 36:921-4. 2004
    ..It is time to harness new technologies and efficiencies of production to mount a high-throughput international effort to produce and phenotype knockouts for all mouse genes, and place these resources into the public domain...

Research Grants24

  1. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC LLOYD; Fiscal Year: 2007
    ..These relationships allow leveraging of MMRRCsupport, resulting in expanded opportunities for, and benefit to, the MMRRC National Program and the biomedical and behavioral scientific research community. ..
  2. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC KENT LLOYD; Fiscal Year: 2010
    ..By enabling availability and access of such valuable mouse models to the entire research community, the UCD-MMRRC fosters and promotes the discovery of new diagnostics, treatments, and prevention strategies against human diseases. ..
  3. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC LLOYD; Fiscal Year: 2009
    ..These relationships allow leveraging of MMRRCsupport, resulting in expanded opportunities for, and benefit to, the MMRRC National Program and the biomedical and behavioral scientific research community. ..
  4. UCD KOMP Project Repository
    KC LLOYD; Fiscal Year: 2007
    ..org) requests for information. Products and services will be offered to requesting investigators for a reasonable fee, enabling us to cost recover for distribution and to develop a self supporting repository operation within 4 years. ..
  5. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC LLOYD; Fiscal Year: 2005
    ..These relationships allow leveraging of MMRRC support, resulting in expanded opportunities for, and benefit to, the MMRRC National Program and the biomedical and behavioral scientific research community. ..
  6. ADVANCED RESEARCH (YEAR) PROGRAM FOR VET STUDENTS
    KC LLOYD; Fiscal Year: 2007
    ..abstract_text> ..
  7. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC LLOYD; Fiscal Year: 2006
    ..The name of the principal investigator/program director must be provided at the top of each printed page and each continuation page. RESEARCH GRANT ..
  8. UCD MUTANT MOUSE REGIONAL RESOURCE CENTER
    KC KENT LLOYD; Fiscal Year: 2010
    ..By enabling availability and access of such valuable mouse models to the entire research community, the UCD-MMRRC fosters and promotes the discovery of new diagnostics, treatments, and prevention strategies against human diseases. ..