Stephen F Kemp

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. ncbi request reprint Near adult heights after growth hormone treatment in patients with idiopathic short stature or idiopathic growth hormone deficiency
    J Paul Frindik
    University of Arkansas for Medical Sciences, Little Rock, AR, USA
    J Pediatr Endocrinol Metab 16:607-12. 2003
  2. ncbi request reprint Use of magnetic resonance imaging in short stature: data from National Cooperative Growth Study (NCGS) Substudy 8
    Stephen F Kemp
    University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Little Rock 72202 3591, USA
    J Pediatr Endocrinol Metab 15:675-9. 2002
  3. pmc Emerging options in growth hormone therapy: an update
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, Little Rock, AR 72202 3591, USA
    Drug Des Devel Ther 5:411-9. 2011
  4. doi request reprint Insulin-like growth factor-I deficiency in children with growth hormone insensitivity: current and future treatment options
    Stephen F Kemp
    Section of Endocrinology, University of Arkansas for Medical Sciences at Arkansas Children s Hospital, Little Rock, AR 72202, USA
    BioDrugs 23:155-63. 2009
  5. ncbi request reprint Mecasermin rinfabate
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Drugs Today (Barc) 43:149-55. 2007
  6. ncbi request reprint Efficacy and safety of mecasermin rinfabate
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, Little Rock, AR 72202 3591, USA
    Expert Opin Biol Ther 6:533-8. 2006
  7. ncbi request reprint Investigational agents for the treatment of growth hormone-insensitivity syndrome
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, Little Rock, AR 72202 3591, USA
    Expert Opin Investig Drugs 15:409-15. 2006
  8. ncbi request reprint Growth hormone treatment of idiopathic short stature: history and demographic data from the NCGS
    Stephen F Kemp
    University of Arkansas for Medical Sciences at Arkansas Children s Hospital, 800 Marshall Street, Springer Building, Arkansas Children s Hospital, Little Rock, AR 72202, USA
    Growth Horm IGF Res 15:S9-12. 2005
  9. ncbi request reprint Efficacy and safety results of long-term growth hormone treatment of idiopathic short stature
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, 800 Marshall Street, Little Rock, Arkansas 72202 3591, USA
    J Clin Endocrinol Metab 90:5247-53. 2005
  10. ncbi request reprint SomatoKine: is there a use in treating growth disorders?
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, 800 Marshall Street, Little Rock, AR 72202 3591, USA
    Curr Opin Investig Drugs 6:373-7. 2005

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Near adult heights after growth hormone treatment in patients with idiopathic short stature or idiopathic growth hormone deficiency
    J Paul Frindik
    University of Arkansas for Medical Sciences, Little Rock, AR, USA
    J Pediatr Endocrinol Metab 16:607-12. 2003
    ....
  2. ncbi request reprint Use of magnetic resonance imaging in short stature: data from National Cooperative Growth Study (NCGS) Substudy 8
    Stephen F Kemp
    University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Little Rock 72202 3591, USA
    J Pediatr Endocrinol Metab 15:675-9. 2002
    ..These findings are useful in confirming the diagnosis of GHD in children and identifying potential candidates for continued GH replacement in adulthood...
  3. pmc Emerging options in growth hormone therapy: an update
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, Little Rock, AR 72202 3591, USA
    Drug Des Devel Ther 5:411-9. 2011
    ..The challenge for the future is to follow these patients into adulthood to determine whether GH therapy poses any long-term risks...
  4. doi request reprint Insulin-like growth factor-I deficiency in children with growth hormone insensitivity: current and future treatment options
    Stephen F Kemp
    Section of Endocrinology, University of Arkansas for Medical Sciences at Arkansas Children s Hospital, Little Rock, AR 72202, USA
    BioDrugs 23:155-63. 2009
    ..There has been some interest in using mecasermin to treat patients with partial GH resistance or idiopathic short stature. At the present time, the data are insufficient to make this recommendation...
  5. ncbi request reprint Mecasermin rinfabate
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Drugs Today (Barc) 43:149-55. 2007
    ..Mecasermin rinfabate prolongs the half-life of rhIGF and should counteract acute adverse events, particularly hypoglycemia, associated with the administration of IGF-I...
  6. ncbi request reprint Efficacy and safety of mecasermin rinfabate
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, Little Rock, AR 72202 3591, USA
    Expert Opin Biol Ther 6:533-8. 2006
    ....
  7. ncbi request reprint Investigational agents for the treatment of growth hormone-insensitivity syndrome
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, Little Rock, AR 72202 3591, USA
    Expert Opin Investig Drugs 15:409-15. 2006
    ..There are no studies comparing the efficacy of mecasermin with mecasermin rinfabate; both drugs have been shown to be effective but cannot be differentiated in terms of efficacy...
  8. ncbi request reprint Growth hormone treatment of idiopathic short stature: history and demographic data from the NCGS
    Stephen F Kemp
    University of Arkansas for Medical Sciences at Arkansas Children s Hospital, 800 Marshall Street, Springer Building, Arkansas Children s Hospital, Little Rock, AR 72202, USA
    Growth Horm IGF Res 15:S9-12. 2005
    ..This most recent analysis of patients enrolled in the NCGS provides a framework for examining the impact of this new indication for GH on clinical practice patterns...
  9. ncbi request reprint Efficacy and safety results of long-term growth hormone treatment of idiopathic short stature
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, 800 Marshall Street, Little Rock, Arkansas 72202 3591, USA
    J Clin Endocrinol Metab 90:5247-53. 2005
    ..Small clinical trials of GH treatment of idiopathic short stature (ISS) show variable efficacy...
  10. ncbi request reprint SomatoKine: is there a use in treating growth disorders?
    Stephen F Kemp
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, 800 Marshall Street, Little Rock, AR 72202 3591, USA
    Curr Opin Investig Drugs 6:373-7. 2005
    ..SomatoKine appears to have a longer half-life in patients with GHIS than unbound IGF-I and fewer adverse events (including hypoglycemia) have been reported when administered to patients with diabetes...
  11. ncbi request reprint Pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient children
    S F Kemp
    University of Arkansas for Medical Sciences at Arkansas Children s Hospital, 800 Marshall Street, Springer Building, Little Rock, AR 72202, USA
    J Clin Endocrinol Metab 89:3234-40. 2004
    ..Nutropin Depot administration once or twice per month provides serum levels of GH and IGF-I expected to promote growth, without accumulation of GH, IGF-I, or IGF binding protein-3, in children with GHD...
  12. doi request reprint Insulin pump therapy started at the time of diagnosis: effects on glycemic control and pancreatic β-cell function in type 1 diabetes
    Kathryn M Thrailkill
    Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202, USA
    Diabetes Technol Ther 13:1023-30. 2011
    ....
  13. doi request reprint Growth and growth hormone treatment in children with chronic diseases
    Alba Morales Pozzo
    Arkansas Children s Hospital, University of Arkansas for Medical Sciences, Little Rock, AR 72202 3591, USA
    Endocrinol Metab Clin North Am 41:747-59. 2012
    ..Examples of such diseases are cystic fibrosis, chronic arthritis, short bowel syndrome, burn trauma, and hypophosphatemic rickets...
  14. pmc Matrix metalloproteinase-2 dysregulation in type 1 diabetes
    Kathryn M Thrailkill
    Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202, USA
    Diabetes Care 30:2321-6. 2007
    ..Our objective was to explore whether systemic MMP-2 dysregulation could be demonstrated in type 1 diabetes and to determine how MMP-2 concentration relates to disease status...
  15. pmc Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues
    Kathryn M Thrailkill
    Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children s Hospital, 800 Marshall St, Springer Bldg, Mail Slot 512 6, Little Rock, AR 72202, USA
    Am J Physiol Endocrinol Metab 289:E735-45. 2005
    ..In so doing, we present evidence that insulin, acting as an anabolic agent in bone, can preserve and increase bone density and bone strength, presumably through direct and/or indirect effects on bone formation...
  16. pmc Managing idiopathic short stature: role of somatropin (rDNA origin) for injection
    J Paul Frindik
    University of Arkansas for Medical Sciences and Arkansas Children s Hospital, AR, USA
    Biologics 4:147-55. 2010
    ....
  17. ncbi request reprint Hypercalcemia in an 11-year-old girl
    Teresa A Nimmo
    Department of Endocrinology, University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Little Rock, Arkansas 72202, USA
    Endocr Pract 13:198-201. 2007
  18. ncbi request reprint Height and social adjustment
    Stephen F Kemp
    Pediatrics 115:515-6; author reply 516-7. 2005
  19. ncbi request reprint Update of guidelines for the use of growth hormone in children: the Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee
    Thomas A Wilson
    Division of Pediatric Endocrinology, State University of New York at Stony Brook, Stony Brook, NY 11794 8111, USA
    J Pediatr 143:415-21. 2003
  20. ncbi request reprint Twenty years of recombinant human growth hormone in children: relevance to pediatric care providers
    Dana S Hardin
    Ohio State University and Columbus Children s Hospital, Columbus, OH 43205, USA
    Clin Pediatr (Phila) 46:279-86. 2007
    ....
  21. ncbi request reprint Bisphosphonate treatment of pediatric bone disease
    Phyllis W Speiser
    Schneider Children s Hospital and New York University School of Medicine, New Hyde Park, NY 11040, USA
    Pediatr Endocrinol Rev 3:87-96. 2005
    ....