Research Topics | Natalie A KelseySummaryAffiliation: University of Denver Country: USA Publications
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Nutraceutical antioxidants as novel neuroprotective agentsNatalie A Kelsey
Department of Biological Sciences and Eleanor Roosevelt Institute, University of Denver, Denver, Colorado 80208, USA
Molecules 15:7792-814. 2010..Here, we review the literature pertaining to these various classes of nutraceutical antioxidants and discuss their potential therapeutic value in neurodegenerative diseases...
Green tea epigallocatechin 3-gallate accumulates in mitochondria and displays a selective antiapoptotic effect against inducers of mitochondrial oxidative stress in neuronsEmily K Schroeder
Research Service, Veterans Affairs Medical Center, Denver, Colorado, USA
Antioxid Redox Signal 11:469-80. 2009..These properties of EGCG make it an interesting therapeutic candidate for neurodegenerative diseases involving neuronal apoptosis triggered by mitochondrial oxidative stress...
Caspases indirectly regulate cleavage of the mitochondrial fusion GTPase OPA1 in neurons undergoing apoptosisF Alexandra Loucks
Research Service, Veterans Affairs Medical Center, Denver, Colorado, USA
Brain Res 1250:63-74. 2009..These data are the first to demonstrate OPA1 cleavage during neuronal apoptosis and they implicate caspases as indirect regulators of OPA1 processing in degenerating neurons...
