Libusha Kelly

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc A survey of integral alpha-helical membrane proteins
    Libusha Kelly
    Graduate Group in Bioinformatics, University of California at San Francisco, San Francisco, CA, USA
    J Struct Funct Genomics 10:269-80. 2009
  2. pmc MODBASE, a database of annotated comparative protein structure models and associated resources
    Ursula Pieper
    Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, University of California at San Francisco, 1700 4th Street, San Francisco, CA 94158, USA
    Nucleic Acids Res 37:D347-54. 2009
  3. pmc Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains
    Libusha Kelly
    Graduate Group in Bioinformatics, University of California at San Francisco, San Francisco, California, USA
    Protein Sci 19:2110-21. 2010
  4. pmc Ratiocinative screen of eukaryotic integral membrane protein expression and solubilization for structure determination
    Franklin A Hays
    Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA 94158 2517, USA
    J Struct Funct Genomics 10:9-16. 2009
  5. pmc MODBASE: a database of annotated comparative protein structure models and associated resources
    Ursula Pieper
    Department of Biopharmaceutical Sciences, California Institute for Quantitative Biomedical Research, QB3 at Mission Bay, Office 503B, University of California at San Francisco 1700 4th Street, San Francisco, CA 94158, USA
    Nucleic Acids Res 34:D291-5. 2006
  6. pmc Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening
    Min Li
    Membrane Protein Expression Center, University of California at San Francisco, San Francisco, CA 94158 2517, USA
    J Mol Biol 385:820-30. 2009
  7. pmc Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies
    Ursula Pieper
    Department of Biopharmaceutical Sciences, California Institute for Quantitative Biosciences, University of California at San Francisco, San Francisco, CA 94158, USA
    J Struct Funct Genomics 10:107-25. 2009
  8. ncbi request reprint LS-SNP: large-scale annotation of coding non-synonymous SNPs based on multiple information sources
    Rachel Karchin
    Department of Biopharmaceutical Sciences, University of California at San Francisco, San Francisco, CA 94143, USA
    Bioinformatics 21:2814-20. 2005
  9. ncbi request reprint PharmGKB submission update: IV. PMT submissions of genetic variations in ATP-Binding cassette transporters to the PharmGKB network
    Tan D Nguyen
    Department of Biopharmaceutical Sciences, University of California, San Francisco, USA
    Pharmacol Rev 58:1-2. 2006

Collaborators

Detail Information

Publications9

  1. pmc A survey of integral alpha-helical membrane proteins
    Libusha Kelly
    Graduate Group in Bioinformatics, University of California at San Francisco, San Francisco, CA, USA
    J Struct Funct Genomics 10:269-80. 2009
    ....
  2. pmc MODBASE, a database of annotated comparative protein structure models and associated resources
    Ursula Pieper
    Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, University of California at San Francisco, 1700 4th Street, San Francisco, CA 94158, USA
    Nucleic Acids Res 37:D347-54. 2009
    ..MODBASE models are also available through the Protein Model Portal (http://www.proteinmodelportal.org/)...
  3. pmc Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains
    Libusha Kelly
    Graduate Group in Bioinformatics, University of California at San Francisco, San Francisco, California, USA
    Protein Sci 19:2110-21. 2010
    ..Our analysis provides a structural and evolutionary framework for rationalizing and predicting the functional effects of nsSNPs in this clinically important membrane transporter superfamily...
  4. pmc Ratiocinative screen of eukaryotic integral membrane protein expression and solubilization for structure determination
    Franklin A Hays
    Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA 94158 2517, USA
    J Struct Funct Genomics 10:9-16. 2009
    ..A screen of 384 rationally selected eukaryotic IMPs in baker's yeast Saccharomyces cerevisiae is outlined to demonstrate the results expected when applying this discovery-oriented pipeline to whole-organism membrane proteomes...
  5. pmc MODBASE: a database of annotated comparative protein structure models and associated resources
    Ursula Pieper
    Department of Biopharmaceutical Sciences, California Institute for Quantitative Biomedical Research, QB3 at Mission Bay, Office 503B, University of California at San Francisco 1700 4th Street, San Francisco, CA 94158, USA
    Nucleic Acids Res 34:D291-5. 2006
    ..org/pibase) as well as predictions of ligand binding sites, interactions between yeast proteins, and functional consequences of human nsSNPs (LS-SNP, http://salilab.org/LS-SNP)...
  6. pmc Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening
    Min Li
    Membrane Protein Expression Center, University of California at San Francisco, San Francisco, CA 94158 2517, USA
    J Mol Biol 385:820-30. 2009
    ..This discovery-oriented pipeline provides an efficient way to select proteins from particular membrane protein classes, families, or organisms that may be more suited to structure analysis than others...
  7. pmc Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies
    Ursula Pieper
    Department of Biopharmaceutical Sciences, California Institute for Quantitative Biosciences, University of California at San Francisco, San Francisco, CA 94158, USA
    J Struct Funct Genomics 10:107-25. 2009
    ....
  8. ncbi request reprint LS-SNP: large-scale annotation of coding non-synonymous SNPs based on multiple information sources
    Rachel Karchin
    Department of Biopharmaceutical Sciences, University of California at San Francisco, San Francisco, CA 94143, USA
    Bioinformatics 21:2814-20. 2005
    ..SNPs that result in amino acid residue changes (nsSNPs) are of critical importance in variation between individuals, including disease and drug sensitivity...
  9. ncbi request reprint PharmGKB submission update: IV. PMT submissions of genetic variations in ATP-Binding cassette transporters to the PharmGKB network
    Tan D Nguyen
    Department of Biopharmaceutical Sciences, University of California, San Francisco, USA
    Pharmacol Rev 58:1-2. 2006