Kristen M Kelly

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Combined photodynamic and photothermal induced injury enhances damage to in vivo model blood vessels
    Kristen M Kelly
    Beckman Laser Institute, University of California, Irvine, California 92612, USA
    Lasers Surg Med 34:407-13. 2004
  2. ncbi request reprint Description and analysis of treatments for port-wine stain birthmarks
    Kristen M Kelly
    Beckman Laser Institute, Irvine, CA 92612, USA
    Arch Facial Plast Surg 7:287-94. 2005
  3. ncbi request reprint Thermal responses of ex vivo human skin during multiple cryogen spurts and 1,450 nm laser pulses
    Rong Zhang
    Beckman Laser Institute, University of California, Irvine, 92612, USA
    Lasers Surg Med 38:137-41. 2006
  4. ncbi request reprint Cutaneous effects of cryogen spray cooling on in vivo human skin
    Nicole Datrice
    Beckman Laser Institute, Irvine, California 92612, USA
    Dermatol Surg 32:1007-12. 2006
  5. ncbi request reprint Microvascular blood flow dynamics associated with photodynamic therapy, pulsed dye laser irradiation and combined regimens
    Tia K Smith
    Beckman Laser Institute, University of California, Irvine, California 92612, USA
    Lasers Surg Med 38:532-9. 2006
  6. ncbi request reprint Evaluation of single versus multiple cryogen spray cooling spurts on in vitro model human skin
    Alia T Tuqan
    Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road East, Irvine, CA, 92612, USA
    Lasers Med Sci 20:80-6. 2005
  7. pmc Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain
    Rolf B Saager
    University of California Irvine, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, California 92612, USA
    J Biomed Opt 16:126013. 2011
  8. ncbi request reprint Use of erythema index imaging for systematic analysis of port wine stain skin response to laser therapy
    Byungjo Jung
    Beckman Laser Institute, University of California, Irvine, CA, USA
    Lasers Surg Med 37:186-91. 2005
  9. pmc Preclinical in vivo evaluation of NPe6-mediated photodynamic therapy on normal vasculature
    Wesley J Moy
    Beckman Laser Institute and Medical Clinic, Department of Surgery, University of California, Irvine, California 92612, USA
    Lasers Surg Med 44:158-62. 2012
  10. pmc Wide-field functional imaging of blood flow and hemoglobin oxygen saturation in the rodent dorsal window chamber
    Austin J Moy
    Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road East, Irvine, CA 92612, USA
    Microvasc Res 82:199-209. 2011

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Combined photodynamic and photothermal induced injury enhances damage to in vivo model blood vessels
    Kristen M Kelly
    Beckman Laser Institute, University of California, Irvine, California 92612, USA
    Lasers Surg Med 34:407-13. 2004
    ..The objective was to evaluate a novel methodology for selective vascular damage, combined photodynamic (PDT) and photothermal (PDL) treatment, using the in vivo chick chorioallantoic membrane (CAM) model...
  2. ncbi request reprint Description and analysis of treatments for port-wine stain birthmarks
    Kristen M Kelly
    Beckman Laser Institute, Irvine, CA 92612, USA
    Arch Facial Plast Surg 7:287-94. 2005
    ....
  3. ncbi request reprint Thermal responses of ex vivo human skin during multiple cryogen spurts and 1,450 nm laser pulses
    Rong Zhang
    Beckman Laser Institute, University of California, Irvine, 92612, USA
    Lasers Surg Med 38:137-41. 2006
    ..The objective of this study is to measure temperature variations at the epidermal-dermal junction in ex vivo human skin during three clinically relevant multiple cryogen spurt-laser pulse sequences (MCS-LPS)...
  4. ncbi request reprint Cutaneous effects of cryogen spray cooling on in vivo human skin
    Nicole Datrice
    Beckman Laser Institute, Irvine, California 92612, USA
    Dermatol Surg 32:1007-12. 2006
    ..Despite widespread clinical use of cryogen spray cooling (CSC) in conjunction with laser dermatologic surgery, in vivo cutaneous effects have not been systematically evaluated...
  5. ncbi request reprint Microvascular blood flow dynamics associated with photodynamic therapy, pulsed dye laser irradiation and combined regimens
    Tia K Smith
    Beckman Laser Institute, University of California, Irvine, California 92612, USA
    Lasers Surg Med 38:532-9. 2006
    ..We further evaluate vascular effects of PDT alone, PDL alone and PDT/PDL in an in vivo rodent dorsal skinfold model...
  6. ncbi request reprint Evaluation of single versus multiple cryogen spray cooling spurts on in vitro model human skin
    Alia T Tuqan
    Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road East, Irvine, CA, 92612, USA
    Lasers Med Sci 20:80-6. 2005
    ..For a constant preset Deltat(c) of 40 ms, delivering cryogen in patterns of shorter MCS increased the actual Deltat(c) and consequently the observed epidermal cryo-injury as compared to an SCS...
  7. pmc Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain
    Rolf B Saager
    University of California Irvine, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, California 92612, USA
    J Biomed Opt 16:126013. 2011
    ..This method was subsequently applied to the determination of PpIX concentration from in vivo normal skin where the model-based correction determined a concentration of 1.6 μg/ml, which is in agreement with literature...
  8. ncbi request reprint Use of erythema index imaging for systematic analysis of port wine stain skin response to laser therapy
    Byungjo Jung
    Beckman Laser Institute, University of California, Irvine, CA, USA
    Lasers Surg Med 37:186-91. 2005
    ....
  9. pmc Preclinical in vivo evaluation of NPe6-mediated photodynamic therapy on normal vasculature
    Wesley J Moy
    Beckman Laser Institute and Medical Clinic, Department of Surgery, University of California, Irvine, California 92612, USA
    Lasers Surg Med 44:158-62. 2012
    ..The objective of the current study was to evaluate a PDT protocol that involves use of an alternate intravascular photosensitizer mono-L-aspartylchlorin-e6 (NPe6) activated by an array of low-cost light emitting diodes...
  10. pmc Wide-field functional imaging of blood flow and hemoglobin oxygen saturation in the rodent dorsal window chamber
    Austin J Moy
    Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road East, Irvine, CA 92612, USA
    Microvasc Res 82:199-209. 2011
    ..Compared with intravital microscopy, wide-field functional imaging requires simple instrumentation, is inexpensive, and can give detailed metabolic information over a wide field of view...
  11. pmc Vascular effects of photodynamic and pulsed dye laser therapy protocols
    Jennifer Channual
    Beckman Laser Institute, University of California, Irvine, California 92612, USA
    Lasers Surg Med 40:644-50. 2008
    ..Here, we evaluate PDT alone, PDL alone, and PDT+PDL protocols using an optimized in vivo rodent dorsal window chamber model...
  12. ncbi request reprint Skin model surface temperatures during single and multiple cryogen spurts used in laser dermatologic surgery
    Julio C Ramirez-San-Juan
    Beckman Laser Institute and Medical Clinic, University of California, Irvine, California 92612, USA
    Lasers Surg Med 36:141-6. 2005
    ..In order to address this concern, it is necessary to evaluate the effects of prolonged exposure of human skin phantoms (HSP) to CSC...
  13. pmc Spatial frequency domain imaging of port wine stain biochemical composition in response to laser therapy: a pilot study
    Amaan Mazhar
    Beckman Laser Institute, University of California, Irvine, California 92612, USA
    Lasers Surg Med 44:611-21. 2012
    ..Herein, we present a pilot study using a newly developed, light emitting diode (LED) based spatial frequency domain imaging (SFDI) device to record quantitatively biochemical compositional changes in PWS after laser therapy...
  14. doi request reprint An overview of clinical and experimental treatment modalities for port wine stains
    Jennifer K Chen
    Beckman Laser Institute and Medical Clinic, University of California, Irvine, California, USA
    J Am Acad Dermatol 67:289-304. 2012
    ....
  15. pmc Effects of motion on optical properties in the spatial frequency domain
    John Quan Nguyen
    Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road, Irvine, California 92617 3010, USA
    J Biomed Opt 16:126009. 2011
    ....
  16. ncbi request reprint Treatment of hypertrophic scars and keloids with a radiofrequency device: a study of collagen effects
    Azin Meshkinpour
    Beckman Laser Institute, University of California, Irvine, CA 92612, USA
    Lasers Surg Med 37:343-9. 2005
    ..To determine the efficacy and safety of the ThermaCool TC radiofrequency system for treatment of hypertrophic and keloid scars and evaluate treatment associated collagen changes...
  17. pmc Combined benzoporphyrin derivative monoacid ring photodynamic therapy and pulsed dye laser for port wine stain birthmarks
    Joshua A Tournas
    Beckman Laser Institute, University of California, Irvine, CA 92612, USA
    Photodiagnosis Photodyn Ther 6:195-9. 2009
    ..We propose an alternative treatment option, combined PDT+PDL and performed a proof-of-concept preliminary clinical trial...
  18. ncbi request reprint Characterization of port wine stain skin erythema and melanin content using cross-polarized diffuse reflectance imaging
    Byungjo Jung
    Beckman Laser Institute, Irvine, California 92612 1475, USA
    Lasers Surg Med 34:174-81. 2004
    ..To address these issues, a cross-polarized diffuse reflectance imaging system and color image analysis method has been developed to evaluate quantitatively erythema and melanin content in PWS skin...
  19. ncbi request reprint Evaluation of cryogen spray cooling exposure on in vitro model human skin
    Bunsho Kao
    Beckman Laser Institute and Medical Clinic, Irvine, California 92612, USA
    Lasers Surg Med 34:146-54. 2004
    ..The epidermal and dermal effects of CSC have not been adequately evaluated. To study the potential for epidermal and dermal injury after CSC using an in vitro model of human skin (RAFT)...
  20. ncbi request reprint Novel model for evaluation of epidermal preservation and dermal collagen remodeling following photorejuvenation of human skin
    Bunsho Kao
    Department of Dermatology and Surgery, Beckman Laser Institute and Medical Clinic, University of California, Irvine, California 92612, USA
    Lasers Surg Med 32:115-9. 2003
    ..We describe a novel human skin tissue culture model developed for this purpose...
  21. pmc Quantitative near infrared spectroscopic analysis of Q-Switched Nd:YAG treatment of generalized argyria
    Rolf B Saager
    Beckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, California 92617, USA
    Lasers Surg Med 45:15-21. 2013
    ..No reports have objectively monitored laser treatment of generalized argyria over large areas of skin, nor have long-term outcomes been evaluated...
  22. pmc Enhanced port-wine stain lightening achieved with combined treatment of selective photothermolysis and imiquimod
    Anne Marie Tremaine
    Beckman Laser Institute, University of California, Irvine, Irvine, California 92697 2400, USA
    J Am Acad Dermatol 66:634-41. 2012
    ..Posttreatment vessel recurrence is thought to be a factor that limits efficacy of PDL treatment of PWS. Imiquimod 5% cream is an immunomodulator with antiangiogenic effects...
  23. doi request reprint Evaluation of a long pulsed 1064-nm Nd:YAG laser for improvement in appearance of cellulite
    Anne Truitt
    Department of Dermatology, University of California, Irvine School of Medicine, Irvine, CA 92697 2400, USA
    J Cosmet Laser Ther 14:139-44. 2012
    ..Cellulite is a common, unwanted condition, which is challenging to treat...
  24. pmc An overview of three promising mechanical, optical, and biochemical engineering approaches to improve selective photothermolysis of refractory port wine stains
    Guillermo Aguilar
    Department of Mechanical Engineering, University of California, Riverside, CA, USA
    Ann Biomed Eng 40:486-506. 2012
    ....
  25. ncbi request reprint Treatment of port-wine stain birthmarks using the 1.5-msec pulsed dye laser at high fluences in conjunction with cryogen spray cooling
    Kristen M Kelly
    Department of Surgery, Beckman Laser Institute and Medical Clinic, University of California, Irvine 92612, USA
    Dermatol Surg 28:309-13. 2002
    ..The majority of port-wine stain (PWS) patients treated with the pulsed dye laser (PDL) do not achieve complete blanching. Safe administration of higher fluences has been proposed as a means of improving treatment efficacy...
  26. pmc Wide-field spatial mapping of in vivo tattoo skin optical properties using modulated imaging
    Frederick R Ayers
    University of California Irvine, Beckman Laser Institute, Irvine, California 92612, USA
    Lasers Surg Med 41:442-53. 2009
    ..MI provides quantitative measurements of multi-colored tattooed skin which may help guide treatment and objectively assess response...
  27. pmc The horizon for treating cutaneous vascular lesions
    Amit M Patel
    Department of Dermatology, University of California, Irvine, CA 92612, USA
    Semin Cutan Med Surg 31:98-104. 2012
    ..Photodynamic therapy, antiangiogenic therapy, and evolving methods of sclerotherapy are promising areas of development that may mitigate limitations of current treatments and offer exciting options for patients and their physicians...
  28. ncbi request reprint Prevention and treatment of skin aging
    Jerry L McCullough
    Department of Dermatology, University of California, Irvine, 92697 2400, USA
    Ann N Y Acad Sci 1067:323-31. 2006
    ....
  29. ncbi request reprint What is nonablative photorejuvenation of human skin?
    J Stuart Nelson
    Department of Surgery, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92612, USA
    Semin Cutan Med Surg 21:238-50. 2002
    ....
  30. ncbi request reprint Comparing the effectiveness of 585-nm vs 595-nm wavelength pulsed dye laser treatment of port wine stains in conjunction with cryogen spray cooling
    Cheng Jen Chang
    Department of Plastic Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan
    Lasers Surg Med 31:352-8. 2002
    ..The objective of this study was to compare the efficacy and safety of cryogen spray cooled laser treatment (CSC-LT) at wavelengths of 585 nm vs. 595 nm for port wine stain (PWS) birthmarks in a large series of patients...
  31. ncbi request reprint Synergistic photodynamic and photothermal treatment of port-wine stain?
    Sol Kimel
    Lasers Surg Med 34:80-2. 2004
  32. ncbi request reprint Optimization of laser treatment safety in conjunction with cryogen spray cooling
    Kristen M Kelly
    Arch Dermatol 139:1372-3. 2003
  33. ncbi request reprint Further investigation of pigmentary changes after alexandrite laser hair removal in conjunction with cryogen spray cooling
    Kristen M Kelly
    Dermatol Surg 30:581-2. 2004
  34. ncbi request reprint Confocal microscopy study of nerves and blood vessels in untreated and treated port wine stains: preliminary observations
    Mona M Selim
    Department of Dermatology, University of Minnesota, Minneapolis, Minnesota, USA
    Dermatol Surg 30:892-7. 2004
    ..We investigated this theory and evaluated nerve and blood vessel density, and mean blood vessel size in untreated and treated PWS skin...
  35. pmc The importance of long-term monitoring to evaluate the microvascular response to light-based therapies
    Bernard Choi
    J Invest Dermatol 128:485-8. 2008