J K Kelly

Summary

Affiliation: University of Kansas
Country: USA

Publications

  1. pmc Direct estimation of the mutation rate at dinucleotide microsatellite loci in Arabidopsis thaliana (Brassicaceae)
    T N Marriage
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS, USA
    Heredity (Edinb) 103:310-7. 2009
  2. pmc The genomic signal of partial sweeps in Mimulus guttatus
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas
    Genome Biol Evol 5:1457-69. 2013
  3. ncbi request reprint The genetic analysis of family structured inbreeding depression studies
    J K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Ave, Lawrence, KS 66045 7534, USA
    Heredity (Edinb) 97:346-54. 2006
  4. pmc Epistasis in monkeyflowers
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045, USA
    Genetics 171:1917-31. 2005
  5. ncbi request reprint Family level inbreeding depression and the evolution of plant mating systems
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Ave Lawrence, KS 66045 7534, USA
    New Phytol 165:55-62. 2005
  6. pmc Mutation-selection balance in mixed mating populations
    John K Kelly
    Department Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045 7534, USA
    J Theor Biol 246:355-65. 2007
  7. pmc Testing the rare-alleles model of quantitative variation by artificial selection
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Ave, Lawrence, KS, 66045 7534, USA
    Genetica 132:187-98. 2008
  8. doi request reprint Connecting QTLS to the g-matrix of evolutionary quantitative genetics
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA
    Evolution 63:813-25. 2009
  9. pmc Deleterious mutations and the genetic variance of male fitness components in Mimulus guttatus
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA
    Genetics 164:1071-85. 2003
  10. ncbi request reprint Linking dynamical and population genetic models of persistent viral infection
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA
    Am Nat 162:14-28. 2003

Collaborators

Detail Information

Publications29

  1. pmc Direct estimation of the mutation rate at dinucleotide microsatellite loci in Arabidopsis thaliana (Brassicaceae)
    T N Marriage
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS, USA
    Heredity (Edinb) 103:310-7. 2009
    ..A survey of dinucleotide repeats across the entire Arabidopsis genome indicates that AT repeats are most abundant, followed by CT, and CA...
  2. pmc The genomic signal of partial sweeps in Mimulus guttatus
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas
    Genome Biol Evol 5:1457-69. 2013
    ..This result is consistent with prior studies of M. guttatus and illustrates how molecular evolution can depend on the allele frequency spectrum at quantitative trait loci. ..
  3. ncbi request reprint The genetic analysis of family structured inbreeding depression studies
    J K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Ave, Lawrence, KS 66045 7534, USA
    Heredity (Edinb) 97:346-54. 2006
    ..Finally, we describe a new publicly available computer program titled 'IDG' (Inbreeding Depression Genetics) to execute these procedures...
  4. pmc Epistasis in monkeyflowers
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045, USA
    Genetics 171:1917-31. 2005
    ..The results for these traits suggest that epistatic effects are variable across genetic backgrounds or sets of interacting loci...
  5. ncbi request reprint Family level inbreeding depression and the evolution of plant mating systems
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Ave Lawrence, KS 66045 7534, USA
    New Phytol 165:55-62. 2005
    ..Estimates of quantitative genetic variance components directly inform questions about the genetic basis of ID and should ultimately allow tests of alternative theories of mating system evolution...
  6. pmc Mutation-selection balance in mixed mating populations
    John K Kelly
    Department Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045 7534, USA
    J Theor Biol 246:355-65. 2007
    ..Finally, conflicting results from previous analytical treatments of mutation-selection balance are resolved to assumptions about the life-cycle and the initial fate of mutations...
  7. pmc Testing the rare-alleles model of quantitative variation by artificial selection
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Ave, Lawrence, KS, 66045 7534, USA
    Genetica 132:187-98. 2008
    ..A combination of modern (marker-based mapping) and classical (biometric) techniques will likely to be required to determine the distribution of allele frequencies at loci influencing quantitative traits...
  8. doi request reprint Connecting QTLS to the g-matrix of evolutionary quantitative genetics
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA
    Evolution 63:813-25. 2009
    ....
  9. pmc Deleterious mutations and the genetic variance of male fitness components in Mimulus guttatus
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA
    Genetics 164:1071-85. 2003
    ..The implication is that, if biometric methods are going to yield useful parameter estimates, they will need to consider mutational models more complicated than those typically employed in experimental studies...
  10. ncbi request reprint Linking dynamical and population genetic models of persistent viral infection
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA
    Am Nat 162:14-28. 2003
    ..Inclusion of multiple cell types increases the likelihood of persistent infection and can increase the amount of genetic diversity within the viral population. However, the overall rate of gene sequence evolution may actually be reduced...
  11. ncbi request reprint Inbreeding and the genetic variance in floral traits of Mimulus guttatus
    J K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, 660045 7534, USA
    Heredity (Edinb) 90:77-83. 2003
    ..These results indicate that inbreeding will substantially alter the evolutionary response to natural selection on floral characters...
  12. pmc Interactions among flower-size QTL of Mimulus guttatus are abundant but highly variable in nature
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA
    Genetics 189:1461-71. 2011
    ....
  13. ncbi request reprint Geographical variation in selection, from phenotypes to molecules
    John K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA
    Am Nat 167:481-95. 2006
    ..The results have implications for gene sequence surveys and, perhaps more generally, for interpreting the apparently weak connection between levels of molecular and quantitative trait variation within species...
  14. ncbi request reprint Mating system and the evolution of quantitative traits: an experimental study of Mimulus guttatus
    Liza M Holeski
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Avenue, Lawrence, Kansas 66045 7534, USA
    Evolution 60:711-23. 2006
    ..The study provides an experimental demonstration of how the interaction of selection, genetic drift, and mating system can produce dramatic short-term changes in trait means, variances, and covariances...
  15. doi request reprint Inbreeding depression in an asexual population of Mimulus guttatus
    T N Marriage
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS, USA
    J Evol Biol 22:2320-31. 2009
    ..We discuss a variety of reasons why we see such low load in this study and suggest future research projects to further explore the questions...
  16. ncbi request reprint Genotype x environment interaction for male attractiveness in an acoustic moth: evidence for plasticity and canalization
    A M Danielson-Fran├žois
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS, USA
    J Evol Biol 19:532-42. 2006
    ..We argue that variation persists in natural populations because G x E interactions prevent any one variant from producing the optimal phenotype across all environments...
  17. ncbi request reprint Predicting response to selection on a quantitative trait: a comparison between models for mixed-mating populations
    J K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS, 66045, USA
    J Theor Biol 207:37-56. 2000
    ..The simulations also indicate that direct application of random mating models to partially selfing populations can produce very inaccurate predictions if quantitative trait loci exhibit dominance...
  18. ncbi request reprint Deleterious mutations and genetic variation for flower size in Mimulus guttatus
    J K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence 66045 7534, USA
    Evolution 55:937-42. 2001
    ..However, we obtain negative values for deltaB/deltaM from three independent selection lines. This result is statistically inconsistent with the deleterious-mutation model...
  19. ncbi request reprint Viral infection in internally structured hosts. I. Conditions for persistent infection
    Maria E Orive
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Ave, Lawrence, KS 66045, USA
    J Theor Biol 232:453-66. 2005
    ..Stochastic aspects of viral establishment may also favor increased migration as it tends to dampen the amplitude of fluctuations in population size during the initial transient phase of establishment...
  20. doi request reprint Contribution of chromosomal polymorphisms to the G-matrix of Mimulus guttatus
    Alison Scoville
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS, USA
    New Phytol 183:803-15. 2009
    ..Both QTLs contribute substantially to the genetic variation in pollen viability. The Drive QTL, and perhaps also the inversion, demonstrates the contribution of balancing selection to the maintenance of genetic variation in fitness...
  21. pmc A Bayesian method for the joint estimation of outcrossing rate and inbreeding depression
    V A Koelling
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS 66045, USA
    Heredity (Edinb) 109:393-400. 2012
    ..In addition, we describe how individual maternal inbreeding histories inferred by BORICE may prove useful in studies of inbreeding and its consequences...
  22. ncbi request reprint Molecular evolution near a two-locus balanced polymorphism
    J K Kelly
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS 66045, USA
    J Theor Biol 204:83-101. 2000
    ..The results of the theory are discussed in relation to published gene sequence data, primarily from Drosophila...
  23. doi request reprint The genetics of phenotypic plasticity in plant defense: trichome production in Mimulus guttatus
    Liza M Holeski
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS 66045, USA
    Am Nat 175:391-400. 2010
    ..In a result that is consistent with a central prediction of optimal defense theory, the high allele at this location was from the ancestral population with low constitutive trichome production...
  24. ncbi request reprint Elevated CO2 influences the expression of floral-initiation genes in Arabidopsis thaliana
    Clint J Springer
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS 66045, USA
    New Phytol 178:63-7. 2008
    ..Understanding the mechanisms that account for changes in plant developmental timing at elevated [CO(2)] is critical for predicting the responses of plants to a high-CO(2) world of the near future...
  25. ncbi request reprint Life history affects the evolution of reproductive isolation among species of Coreopsis (Asteraceae)
    Jenny K Archibald
    Department of Ecology and Evolutionary Biology and Natural History Museum and Biodiversity Research Center, University of Kansas, Lawrence 66045, USA
    Evolution 59:2362-9. 2005
    ..The more rapid evolution of reproductive isolation within annual species of Coreopsis may be due to differing mechanisms of reproductive isolation, that is, chromosomal rearrangements rather than genetic incompatibilities...
  26. pmc Effects of spatially varying selection on nucleotide diversity and linkage disequilibrium: insights from deer mouse globin genes
    Jay F Storz
    School of Biological Sciences, University of Nebraska, Lincoln, Nebraska 68588, USA
    Genetics 180:367-79. 2008
    ..Simulation and empirical results indicate that sliding-window analyses of Z(g) between allele classes may provide an effective means of pinpointing causal substitutions...
  27. ncbi request reprint Sex difference in the association of the angiotensin converting enzyme I/D polymorphism and body mass index
    Michael J Wacker
    Department of Basic Medical Science, School of Medicine, University of Missouri Kansas City, Kansas City, MO 64108, USA
    Med Sci Monit 14:CR353-7. 2008
    ..ACE and the components of the renin-angiotensin system are expressed in adipose tissue and therefore the I/D polymorphism within ACE may be associated with obesity...
  28. ncbi request reprint A statistical characterization of consistent patterns of human immunodeficiency virus evolution within infected patients
    Scott Williamson
    Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA
    Mol Biol Evol 22:456-68. 2005
    ....
  29. ncbi request reprint The effects of high-frequency hearing loss on low-frequency components of the click-evoked otoacoustic emission
    Owen D Murnane
    James H Quillen VA Medical Center, Mountain Home, Tennessee 37684, USA
    J Am Acad Audiol 14:525-33. 2003
    ..It is proposed that localized damage at basal cochlear sites affects the generation of low- to midfrequency CEOAE energy...

Research Grants5

  1. A Genomic Analysis of Complex Trait Variation in Mimulus
    John Kelly; Fiscal Year: 2009
    ..The proposed research will have broader impacts thorough both education and the development of scientific resources. ..
  2. Genomic Analysis of Complex Trait Variation in Mimulus
    John Kelly; Fiscal Year: 2006
    ..The proposed research will have broader impacts thorough both education and the development of scientific resources. ..
  3. A Genomic Analysis of Complex Trait Variation in Mimulus
    John Kelly; Fiscal Year: 2007
    ..The proposed research will have broader impacts thorough both education and the development of scientific resources. ..
  4. A Genomic Analysis of Complex Trait Variation in Mimulus
    John Kelly; Fiscal Year: 2009
    ..The proposed research will have broader impacts thorough both education and the development of scientific resources. ..