H William Kelly

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. ncbi Levalbuterol for asthma: a better treatment?
    H William Kelly
    Department of Pediatrics, Pediatrics Pulmonary, MSC10 5590, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
    Curr Allergy Asthma Rep 7:310-4. 2007
  2. pmc Effect of long-term corticosteroid use on bone mineral density in children: a prospective longitudinal assessment in the childhood Asthma Management Program (CAMP) study
    H William Kelly
    Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 0001, USA
    Pediatrics 122:e53-61. 2008
  3. ncbi Leukotriene modifiers
    H William Kelly
    Pediatrics 109:170-1. 2002
  4. pmc Effect of inhaled glucocorticoids in childhood on adult height
    H William Kelly
    University of New Mexico, Albuquerque, USA
    N Engl J Med 367:904-12. 2012
  5. ncbi Pulmonary clinical pharmacy practice
    H William Kelly
    Department of Pediatrics, Pediatrics Pulmonary, MSC10 5590, 1 University of New Mexico, Albuquerque, 87131 0001, USA
    Ann Pharmacother 40:1407-8. 2006
  6. ncbi Non-corticosteroid therapy for the long-term control of asthma
    H William Kelly
    University of New Mexico, Department of Pediatrics, Pediatrics Pulmonary, Albuquerque, New Mexico 87131 0001, USA
    Expert Opin Pharmacother 8:2077-87. 2007
  7. ncbi Rationale for the major changes in the pharmacotherapy section of the National Asthma Education and Prevention Program guidelines
    H William Kelly
    Department of Pediatrics, Pediatrics Pulmonary, University of New Mexico, Albuquerque, NM 87131 0001, USA
    J Allergy Clin Immunol 120:989-94; quiz 995-6. 2007
  8. ncbi What is new with the beta2-agonists: issues in the management of asthma
    H William Kelly
    Department of Pediatrics, Pediatrics Pulmonary, MSC10 5590, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
    Ann Pharmacother 39:931-8. 2005
  9. doi Inhaled corticosteroid dosing: double for nothing?
    H William Kelly
    Department of Pediatrics, University of New Mexico, Albuquerque, NM 87131 0001, USA
    J Allergy Clin Immunol 128:278-281.e2. 2011
  10. ncbi The use of inhaled corticosteroids in children with asthma
    H William Kelly
    Department of Pediatrics, Children s Hospital of New Mexico, ACC Building, 3rd Floor, 2211 Lomas Boulevard NE, Albuquerque, NM 87131 5311, USA
    Curr Allergy Asthma Rep 2:133-43. 2002

Research Grants

  1. CAMP Continuation Study/Phase 3
    H Kelly; Fiscal Year: 2007
  2. CAMP Continuation Study/Phase 3
    H Kelly; Fiscal Year: 2008

Detail Information

Publications36

  1. ncbi Levalbuterol for asthma: a better treatment?
    H William Kelly
    Department of Pediatrics, Pediatrics Pulmonary, MSC10 5590, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
    Curr Allergy Asthma Rep 7:310-4. 2007
    ....
  2. pmc Effect of long-term corticosteroid use on bone mineral density in children: a prospective longitudinal assessment in the childhood Asthma Management Program (CAMP) study
    H William Kelly
    Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 0001, USA
    Pediatrics 122:e53-61. 2008
    ..Thus, we assessed the effects of multiple short courses of oral corticosteroids and long-term inhaled corticosteroids on bone mineral accretion over a period of years...
  3. ncbi Leukotriene modifiers
    H William Kelly
    Pediatrics 109:170-1. 2002
  4. pmc Effect of inhaled glucocorticoids in childhood on adult height
    H William Kelly
    University of New Mexico, Albuquerque, USA
    N Engl J Med 367:904-12. 2012
    ..The resulting decrease in attained height 1 to 4 years after the initiation of inhaled glucocorticoids is thought not to decrease attained adult height...
  5. ncbi Pulmonary clinical pharmacy practice
    H William Kelly
    Department of Pediatrics, Pediatrics Pulmonary, MSC10 5590, 1 University of New Mexico, Albuquerque, 87131 0001, USA
    Ann Pharmacother 40:1407-8. 2006
  6. ncbi Non-corticosteroid therapy for the long-term control of asthma
    H William Kelly
    University of New Mexico, Department of Pediatrics, Pediatrics Pulmonary, Albuquerque, New Mexico 87131 0001, USA
    Expert Opin Pharmacother 8:2077-87. 2007
    ..However, it is the only adjunctive therapy added to the combination of an inhaled corticosteroid plus LABA to demonstrate further improvement in a controlled clinical trial...
  7. ncbi Rationale for the major changes in the pharmacotherapy section of the National Asthma Education and Prevention Program guidelines
    H William Kelly
    Department of Pediatrics, Pediatrics Pulmonary, University of New Mexico, Albuquerque, NM 87131 0001, USA
    J Allergy Clin Immunol 120:989-94; quiz 995-6. 2007
    ..However, the inhaled corticosteroids/LABAs are still recommended for patients with moderate-to-severe persistent asthma. The rationale for the continued recommendation is provided...
  8. ncbi What is new with the beta2-agonists: issues in the management of asthma
    H William Kelly
    Department of Pediatrics, Pediatrics Pulmonary, MSC10 5590, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
    Ann Pharmacother 39:931-8. 2005
    ..To review the more recent literature addressing the issue of whether beta2-agonists can worsen asthma and/or increase the risk of severe exacerbations and death from asthma...
  9. doi Inhaled corticosteroid dosing: double for nothing?
    H William Kelly
    Department of Pediatrics, University of New Mexico, Albuquerque, NM 87131 0001, USA
    J Allergy Clin Immunol 128:278-281.e2. 2011
    ..It is recommended that doubling the dose of an ICS no longer be considered a positive comparator arm in clinical trials, although it might be beneficial in individual patients...
  10. ncbi The use of inhaled corticosteroids in children with asthma
    H William Kelly
    Department of Pediatrics, Children s Hospital of New Mexico, ACC Building, 3rd Floor, 2211 Lomas Boulevard NE, Albuquerque, NM 87131 5311, USA
    Curr Allergy Asthma Rep 2:133-43. 2002
    ..Long-term trials support the existing recommendations of lowering dosage once control is achieved and stopping therapy when the child's asthma is in remission...
  11. pmc Long-term budesonide or nedocromil treatment, once discontinued, does not alter the course of mild to moderate asthma in children and adolescents
    Robert C Strunk
    Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, St Louis, MO 63110, USA
    J Pediatr 154:682-7. 2009
    ..To determine whether long-term, continuous use of inhaled anti-inflammatory medications affects asthma outcomes in children with mild to moderate asthma after use is discontinued...
  12. ncbi Long-term effect of budesonide on hypothalamic-pituitary-adrenal axis function in children with mild to moderate asthma
    Leonard B Bacharier
    Division of Allergy and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, Missouri 63110, USA
    Pediatrics 113:1693-9. 2004
    ..To determine the safety of long-term (36 months) administration of an inhaled corticosteroid (budesonide) on hypothalamic-pituitary-adrenal (HPA) axis function in children with mild to moderate asthma...
  13. ncbi Pretreatment with albuterol versus montelukast for exercise-induced bronchospasm in children
    Hengameh H Raissy
    Departments of Pediatrics, School of Medicine, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
    Pharmacotherapy 28:287-94. 2008
    ....
  14. pmc Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma
    Nathan Rabinovitch
    Department of Pediatrics, National Jewish Health and the University of Colorado Denver School of Medicine, Denver, Colo 80206, USA
    J Allergy Clin Immunol 126:545-51.e1-4. 2010
    ..A subset of children with asthma respond better to leukotriene receptor antagonists than to inhaled corticosteroids. Information is needed to identify children with these preferential responses...
  15. pmc Do oral corticosteroids reduce the severity of acute lower respiratory tract illnesses in preschool children with recurrent wheezing?
    Avraham Beigelman
    Department of Pediatrics, Washington University and St Louis Children s Hospital, St Louis, MO 63110, USA
    J Allergy Clin Immunol 131:1518-25. 2013
    ..Oral corticosteroids (OCSs) are recommended for severe wheezing episodes in children. However, limited evidence supports this intervention in preschool children with outpatient wheezing illnesses...
  16. ncbi Association of hypothalamic-pituitary-adrenal axis function with neuropsychological performance in children with mild/moderate asthma
    Robert D Annett
    University of New Mexico Health Sciences Center, Pediatrics, Albuquerque, NM 87131, USA
    Child Neuropsychol 11:333-48. 2005
    ..In contrast, cortisol production was not associated with child reports of psychological functioning. Limitations to the methods employed in this study are discussed...
  17. doi Comparison of inhaled corticosteroids: an update
    H William Kelly
    University of New Mexico Health Sciences Center, Children s Hospital of New Mexico, 2211 Lomas Blvd NE, Albuquerque, NM 87131, USA
    Ann Pharmacother 43:519-27. 2009
    ....
  18. ncbi Influence of impactor operating flow rate on particle size distribution of four jet nebulizers
    Yue Zhou
    Lovelace Respiratory Research Institute, Albuquerque, NM, USA
    Pharm Dev Technol 12:353-9. 2007
    ..3 L/min. The higher MMAD and GSD could cause the patient to inhale less of the drug than expected if the nebulizer was evaluated by the ACI at the operating flow rate of 28.3 L/min...
  19. ncbi Comparison of the dose response to levalbuterol with and without pretreatment with S-albuterol after methacholine-induced bronchoconstriction
    Hengameh H Raissy
    School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
    Pharmacotherapy 27:1231-6. 2007
    ..To determine the effect of S-albuterol on the dose response to levalbuterol in patients with moderate bronchoconstriction induced by a methacholine challenge...
  20. pmc Inhaled corticosteroids in lung diseases
    Hengameh H Raissy
    Department of Pediatrics, School of Medicine, University of New Mexico, Albuquerque, NM, USA
    Am J Respir Crit Care Med 187:798-803. 2013
    ....
  21. ncbi Growth and bone density in children with mild-moderate asthma: a cross-sectional study in children entering the Childhood Asthma Management Program (CAMP)
    H William Kelly
    Department of Pediatrics, School of Medicine, and the College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 5311, USA
    J Pediatr 142:286-91. 2003
    ..We sought to determine whether mild-moderate persistent asthma sufficient to produce a decrease in baseline lung function is associated with an adverse effect on growth and bone mineral density (BMD) in children...
  22. ncbi Potential adverse effects of the inhaled corticosteroids
    H William Kelly
    Department of Pediatrics, University of New Mexico Children s Hospital, ACC Building 3rd Floor, 2211 Lomas Boulevard NE, Albuquerque, NM 87131 5311, USA
    J Allergy Clin Immunol 112:469-78; quiz 479. 2003
    ..The data are insufficient to determine whether there is an effect on attainment of predicted adult height. The ICSs affect bone mineral density and risk of fractures in a dose-dependent fashion that appears significant at high doses...
  23. ncbi Immune response to hepatitis B vaccine in asthmatic children
    Barbara Masten
    Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
    Pediatr Pulmonol 36:522-8. 2003
    ....
  24. pmc The role of inhaled long-acting beta-2 agonists in the management of asthma
    H William Kelly
    Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    J Natl Med Assoc 98:8-16. 2006
    ..A concentration on the clinical pharmacology and genetic implications for clinical use of this class of drugs in accordance with the national and international guidelines are described...
  25. ncbi Randomized, placebo-controlled trial of albuterol and epinephrine at equipotent beta-2 agonist doses in acute bronchiolitis
    Shawn Ralston
    Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
    Pediatr Pulmonol 40:292-9. 2005
    ....
  26. ncbi Withdrawal from lorazepam in critically ill children
    Karen D Dominguez
    College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, 87131, USA
    Ann Pharmacother 40:1035-9. 2006
    ..Sedatives are used in critically ill children to facilitate mechanical ventilation. Although tolerance and withdrawal are associated with use of sedatives, information about withdrawal from benzodiazepines in children is limited...
  27. ncbi Opioid withdrawal in critically ill neonates
    Karen D Dominguez
    College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    Ann Pharmacother 37:473-7. 2003
    ..To determine the occurrence of and risk factors for opioid withdrawal in critically ill neonates receiving continuous infusions of fentanyl...
  28. ncbi The role of pharmacists in the evolution of health care: an open forum discussion
    H William Kelly
    Department of Pediatricsrmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Pharmacotherapy 26:200S-2S. 2006
    ..The new Medicare Part D program is a real opportunity for pharmacists to be actively engaged in patient education and treatment monitoring...
  29. ncbi Risk versus benefit considerations for the beta(2)-agonists
    H William Kelly
    Department of Pediatrics, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Pharmacotherapy 26:164S-74S. 2006
    ..The preclinical and clinical effects of these two stereoisomers are reviewed. Data describing the efficacy and safety of levalbuterol (R-albuterol) and racemic albuterol are presented...
  30. ncbi Pharmaceutical characteristics that influence the clinical efficacy of inhaled corticosteroids
    H William Kelly
    Department of Pediatrics, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 5311, USA
    Ann Allergy Asthma Immunol 91:326-34; quiz 334-5, 404. 2003
    ..Direct estimates of clinical efficacy and potency based on studies in humans are difficult to interpret...
  31. ncbi The assessment of childhood asthma
    H William Kelly
    Department of Pediatrics, University of New Mexico Health Sciences Center, 2211 Loma Blvd NE, Albuquerque, NM 87131, USA
    Pediatr Clin North Am 50:593-608. 2003
    ..Measures of AHR, particularly methacholine provocation, and the measurement of FeNO are attractive as assessments of ongoing asthma activity in children when lung function and symptoms are normal...
  32. ncbi Comparison of two methods of delivering continuously nebulized albuterol
    H William Kelly
    Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131 5311, USA
    Ann Pharmacother 37:23-6. 2003
    ..To compare the relative delivery of 2 methods for providing continuously nebulized albuterol (CNA): a small-volume nebulizer plus infusion pump versus a large-volume nebulizer...
  33. ncbi Approaching value in asthma management: the need to integrate clinical and economic research with the basic science
    David A Stempel
    Virginia Mason Medical Center, 1100 Ninth Avenue, Seattle, WA 98101, USA
    J Allergy Clin Immunol 109:S503-10. 2002
    ..Taken together, the results of such analyses form a foundation for providing effective, safe, and cost-efficient care through the practice of evidence-based medicine...
  34. ncbi Severe, acute asthma as therapeutic orphan
    H William Kelly
    Ann Pharmacother 36:1287-9. 2002
  35. ncbi Antibiotic use in cystic fibrosis. 1984
    H William Kelly
    Ann Pharmacother 40:1424-35. 2006
  36. ncbi Chronic illness care in Russia: a pilot project to improve asthma care in a "closed city"
    Phillip A Hertzman
    Los Alamos Medical Center, Suite 130, West Rd, Los Alamos, NM 87544, USA
    Chest 127:861-5. 2005
    ..In Russia, where health status has deteriorated since the late 1960s, asthma is a growing medical and public health problem...

Research Grants2

  1. CAMP Continuation Study/Phase 3
    H Kelly; Fiscal Year: 2007
    ..End of Abstract.) ..
  2. CAMP Continuation Study/Phase 3
    H Kelly; Fiscal Year: 2008
    ..End of Abstract.) ..