Douglas R Kellogg

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Control of mitotic events by Nap1 and the Gin4 kinase
    R Altman
    Sinsheimer Laboratories, Department of Biology, University of California, Santa Cruz, California 95064, USA
    J Cell Biol 138:119-30. 1997
  2. ncbi request reprint Wee1-dependent mechanisms required for coordination of cell growth and cell division
    Douglas R Kellogg
    Sinsheimer Laboratories, Department of Molecular, Cellular and Developmental Biology, University of California, Santa Cruz, CA 95064, USA
    J Cell Sci 116:4883-90. 2003
  3. pmc The septins function in G1 pathways that influence the pattern of cell growth in budding yeast
    Thea A Egelhofer
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
    PLoS ONE 3:e2022. 2008
  4. pmc Grapes(Chk1) prevents nuclear CDK1 activation by delaying cyclin B nuclear accumulation
    Anne Royou
    Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    J Cell Biol 183:63-75. 2008
  5. pmc The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase
    Sidonie Wicky
    Department of Molecular, Cell, and Developmental Biology, Univ of California, Santa Cruz, CA 95064, USA
    Mol Biol Cell 22:20-32. 2011
  6. pmc The Rts1 regulatory subunit of protein phosphatase 2A is required for control of G1 cyclin transcription and nutrient modulation of cell size
    Karen Artiles
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
    PLoS Genet 5:e1000727. 2009
  7. pmc A link between mitotic entry and membrane growth suggests a novel model for cell size control
    Steph D Anastasia
    Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    J Cell Biol 197:89-104. 2012
  8. pmc A phosphatase threshold sets the level of Cdk1 activity in early mitosis in budding yeast
    Stacy L Harvey
    Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    Mol Biol Cell 22:3595-608. 2011
  9. ncbi request reprint Cdc28-dependent regulation of the Cdc5/Polo kinase
    Eric M Mortensen
    Sinsheimer Labs, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California 95064, USA
    Curr Biol 15:2033-7. 2005
  10. pmc Regulation of Mih1/Cdc25 by protein phosphatase 2A and casein kinase 1
    Gayatri Pal
    Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    J Cell Biol 180:931-45. 2008

Collaborators

  • Noah Dephoure
  • Mart Loog
  • Danesh Moazed
  • Jason Stumpff
  • Anne Royou
  • Jeremy Gunawardena
  • Judit Villen
  • T T Su
  • WILLIAM T SULLIVAN
  • Anthony C Bishop
  • Stacy L Harvey
  • Steven P Gygi
  • Derek McCusker
  • Eva Rose M Balog
  • Eric M Mortensen
  • Thea A Egelhofer
  • John Yates
  • Jessica Zapata
  • Tracy Macdonough
  • Denise A McGrath
  • Steph D Anastasia
  • Seth M Rubin
  • Vu Thai
  • Sidonie Wicky
  • Karen Artiles
  • Gayatri Pal
  • David Schieltz
  • Michael T Nehil
  • Wilhelm Haas
  • Arun K Kashyap
  • Aparna Sreenivasan
  • Yaxin Yu
  • David J Stillman
  • Meghan Mooring
  • Emily J Parnell
  • Michelle V Mai
  • Rafael Lucena
  • Alexander Hirschi
  • Mardo Kõivomägi
  • Melissa Meloy
  • Duy Linh Nguyen
  • Hendri Tjandra
  • German Enciso
  • Ou Chong Saetern
  • Cassidy O Hoeft
  • William Finch
  • Stephanie Anastasia
  • Maria T Z Paraz
  • John R Yates
  • R Scott Lokey
  • David J Combs
  • Craig M Tamble
  • Carilee Denison
  • Scott Anderson
  • Alyson Charlet
  • Melanie Gygi
  • R Altman
  • Kevan M Shokat
  • Hayes McDonald

Detail Information

Publications22

  1. pmc Control of mitotic events by Nap1 and the Gin4 kinase
    R Altman
    Sinsheimer Laboratories, Department of Biology, University of California, Santa Cruz, California 95064, USA
    J Cell Biol 138:119-30. 1997
    ..These results demonstrate that the activation of Gin4 is under the control of Clb2 and Nap1, and they provide an important step towards elucidating the molecular pathways that link cyclin-dependent kinases to the events they control...
  2. ncbi request reprint Wee1-dependent mechanisms required for coordination of cell growth and cell division
    Douglas R Kellogg
    Sinsheimer Laboratories, Department of Molecular, Cellular and Developmental Biology, University of California, Santa Cruz, CA 95064, USA
    J Cell Sci 116:4883-90. 2003
    ..Further understanding of these signaling networks may provide important clues to how cell growth and cell division are coordinated...
  3. pmc The septins function in G1 pathways that influence the pattern of cell growth in budding yeast
    Thea A Egelhofer
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
    PLoS ONE 3:e2022. 2008
    ..Phosphorylation of Shs1 by G1 cyclin-dependent kinases plays a role in events that influence Cdk1 inhibitory phosphorylation...
  4. pmc Grapes(Chk1) prevents nuclear CDK1 activation by delaying cyclin B nuclear accumulation
    Anne Royou
    Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    J Cell Biol 183:63-75. 2008
    ..Grp(Chk1) prevents nuclear CDK1 activation by delaying CycB nuclear accumulation through Wee1-dependent and independent mechanisms...
  5. pmc The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase
    Sidonie Wicky
    Department of Molecular, Cell, and Developmental Biology, Univ of California, Santa Cruz, CA 95064, USA
    Mol Biol Cell 22:20-32. 2011
    ..Together, these observations define a role for the Zds proteins in controlling specific functions of PP2A(Cdc55) and suggest that upstream signals that regulate PP2A(Cdc55) may play an important role in controlling entry into mitosis...
  6. pmc The Rts1 regulatory subunit of protein phosphatase 2A is required for control of G1 cyclin transcription and nutrient modulation of cell size
    Karen Artiles
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
    PLoS Genet 5:e1000727. 2009
    ..Together, these observations demonstrate that Rts1 is a key player in pathways that link nutrient availability, cell size, and G1 cyclin transcription. Since Rts1 is highly conserved, it may function in similar pathways in vertebrates...
  7. pmc A link between mitotic entry and membrane growth suggests a novel model for cell size control
    Steph D Anastasia
    Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    J Cell Biol 197:89-104. 2012
    ..Growth-dependent signaling could explain how membrane growth is integrated with cell cycle progression. It could also control both cell size and morphogenesis, thereby reconciling divergent models for mitotic checkpoint function...
  8. pmc A phosphatase threshold sets the level of Cdk1 activity in early mitosis in budding yeast
    Stacy L Harvey
    Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    Mol Biol Cell 22:3595-608. 2011
    ..These results define a new role for PP2A(Cdc55) and reveal a systems-level mechanism by which dynamically opposed kinase and phosphatase activities can modulate signal strength...
  9. ncbi request reprint Cdc28-dependent regulation of the Cdc5/Polo kinase
    Eric M Mortensen
    Sinsheimer Labs, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California 95064, USA
    Curr Biol 15:2033-7. 2005
    ..Analysis of Cdc5 phosphorylation by mass spectrometry indicates that threonine 242 is phosphorylated in vivo. These results suggest that Cdc28 activates Cdc5 via phosphorylation of threonine 242...
  10. pmc Regulation of Mih1/Cdc25 by protein phosphatase 2A and casein kinase 1
    Gayatri Pal
    Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA
    J Cell Biol 180:931-45. 2008
    ..Because casein kinase 1 is associated with sites of polar growth, it may regulate Mih1 as part of a signaling mechanism that links successful completion of growth-related events to cell cycle progression...
  11. doi request reprint Cks confers specificity to phosphorylation-dependent CDK signaling pathways
    Denise A McGrath
    1 Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, California, USA 2
    Nat Struct Mol Biol 20:1407-14. 2013
    ..Together, our results portray Cks as a multifunctional phosphoadaptor that serves as a specificity factor for CDK activity. ..
  12. pmc PP2ARts1 is a master regulator of pathways that control cell size
    Jessica Zapata
    Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064
    J Cell Biol 204:359-76. 2014
    ..We hypothesize that control of Ace2 by PP2A(Rts1) plays a role in mechanisms that link G1 cyclin accumulation to cell growth. ..
  13. ncbi request reprint Cdk1 coordinates cell-surface growth with the cell cycle
    Derek McCusker
    Department of Molecular, Cell and Developmental Biology, University of California, 1156 High Street, Santa Cruz, CA 95064, USA
    Nat Cell Biol 9:506-15. 2007
    ..A mutant form of a Cdc24-associated protein that fails to undergo Cdk1-dependent phosphorylation causes defects in bud growth. These results provide a direct link between Cdk1 activity and the control of polarized cell growth...
  14. pmc Cell cycle-dependent assembly of a Gin4-septin complex
    Eric M Mortensen
    Department of Molecular, Cellular, and Developmental Biology, Sinsheimer Labs, University of California, Santa Cruz, California 95065, USA
    Mol Biol Cell 13:2091-105. 2002
    ..In addition, these results provide clues to how Gin4 may regulate the localization or function of the septins...
  15. pmc Drosophila Wee1 interacts with members of the gammaTURC and is required for proper mitotic-spindle morphogenesis and positioning
    Jason Stumpff
    Department of Molecular, Cellular, and Developmental Biology, 347 UCB, University of Colorado, Boulder Boulder, Colorado 80309, USA
    Curr Biol 15:1525-34. 2005
    ..Wee1 kinases delay entry into mitosis by phosphorylating and inactivating cyclin-dependent kinase 1 (Cdk1). Loss of this activity in many systems, including Drosophila, leads to premature mitotic entry...
  16. ncbi request reprint Cdk1-dependent regulation of the mitotic inhibitor Wee1
    Stacy L Harvey
    Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California 95064, USA
    Cell 122:407-20. 2005
    ..Thus, Cdk1 both positively and negatively regulates its own inhibitor. Regulation of the Swe1-Cdk1 complex is likely to play a critical role in controlling the transition into mitosis...
  17. ncbi request reprint Conservation of mechanisms controlling entry into mitosis: budding yeast wee1 delays entry into mitosis and is required for cell size control
    Stacy L Harvey
    Department of Molecular, Cellular, and Developmental Biology, Sinsheimer Labs, University of California, Santa Cruz, CA 95064, USA
    Curr Biol 13:264-75. 2003
    ..SWE1, the budding yeast homolog of wee1, is thought to function in a morphogenesis checkpoint that delays entry into mitosis in response to defects in bud morphogenesis...
  18. doi request reprint The structure of a monomeric mutant Cks protein reveals multiple functions for a conserved hinge-region proline
    Eva Rose M Balog
    Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, CA 95064, USA
    J Mol Biol 411:520-8. 2011
    ....
  19. pmc Specific inhibition of Elm1 kinase activity reveals functions required for early G1 events
    Aparna Sreenivasan
    Sinsheimer Laboratories, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Cruz, California 95064, USA
    Mol Cell Biol 23:6327-37. 2003
    ..These results demonstrate that the Elm1 kinase plays an important role in G(1) events required for bud emergence and septin organization...
  20. ncbi request reprint Biochemical and genetic characterization of Yra1p in budding yeast
    Arun K Kashyap
    Sinsheimer Labs, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Cruz, CA 95064, USA
    Yeast 22:43-56. 2005
    ..Taken together, these results suggest that Yra1p has roles in diverse RNA processing events in addition to a role in mRNA export...
  21. ncbi request reprint Uncovering genetic relationships using small molecules that selectively target yeast cell cycle mutants
    Michael T Nehil
    University of California, San Francisco, CA, USA
    Chem Biol Drug Des 69:258-64. 2007
    ..These results suggest an approach for combining chemical synthetic lethality and chemical genomic screens to uncover novel genetic interactions that can be applied to other eukaryotic pathways of interest...
  22. ncbi request reprint Protein- and immunoaffinity purification of multiprotein complexes
    Douglas R Kellogg
    Department of Biology, Sinsheimer Laboratories, University of California, Santa Cruz, California 95064, USA
    Methods Enzymol 351:172-83. 2002