Jeremy D Keenan
Affiliation: University of California
- Diagnostic characteristics of tests for ocular Chlamydia after mass azithromycin distributionsJeremy D Keenan
F I Proctor Foundation, 513 Parnassus Avenue, Med Sci S309, Box 0412, University of California, San Francisco, San Francisco, CA 94143 0412, USA
Invest Ophthalmol Vis Sci 53:235-40. 2012....
- Antibiotic selection pressure and macrolide resistance in nasopharyngeal Streptococcus pneumoniae: a cluster-randomized clinical trialAlison H Skalet
Francis I Proctor Foundation for Research in Opthalmology, University of California, San Francisco, San Francisco, California, United States of America
PLoS Med 7:e1000377. 2010..In this study, we used a randomized clinical trial design to assess whether macrolide resistance was higher in communities treated with mass azithromycin for trachoma, compared to untreated control communities...
- Risk factors for ocular chlamydia after three mass azithromycin distributionsBerhan Ayele
The Carter Center, Addis Ababa, Ethiopia
PLoS Negl Trop Dis 5:e1441. 2011..Knowledge of characteristics associated with infection after mass antibiotic treatments could allow trachoma programs to focus resources to those most likely to be infected with ocular chlamydia...
- Importance of coverage and endemicity on the return of infectious trachoma after a single mass antibiotic distributionTakele Lakew
ORBIS International, Addis Ababa, Ethiopia
PLoS Negl Trop Dis 3:e507. 2009..A wider range of antibiotic coverage than found in this study might allow an assessment of a more subtle association...
- Chlamydial infection during trachoma monitoring: are the most difficult-to-reach children more likely to be infected?Jeremy D Keenan
Francis I Proctor Foundation, San Francisco, CA 94143 0412, USA
Trop Med Int Health 17:392-6. 2012..We sought to determine whether individuals who are difficult to locate were more likely to be infected with ocular chlamydia than those who were easier to locate...
- Ribosomal RNA evidence of ocular Chlamydia trachomatis infection following 3 annual mass azithromycin distributions in communities with highly prevalent trachomaJeremy D Keenan
FI Proctor Foundation, Department of Ophthalmology, University of California, San Francisco, CA 94143 0412, USA
Clin Infect Dis 54:253-6. 2012..An RNA-based test detected ocular chlamydial infection in more children than did a DNA-based test (6.9% vs 4.2%), and in a larger number of communities (8 vs 7)...
- Perifosine-related rapidly progressive corneal ring infiltrateJeremy D Keenan
F I Proctor Foundation and the Department of Ophthalmology, University of California, San Francisco, San Francisco, CA 94143 0944, USA
Cornea 29:583-5. 2010..To report a case of unilateral rapidly progressing corneal ring infiltration in a patient being treated with the investigational drug perifosine for Waldenström's macroglobulinemia...
- Peripheral ulcerative keratitis associated with vasculitis manifesting asymmetrically as fuchs superficial marginal keratitis and terrien marginal degenerationJeremy D Keenan
F I Proctor Foundation, University of California, San Francisco, CA, USA
Cornea 30:825-7. 2011..To report a case of bilateral peripheral corneal thinning with an appearance of Fuchs superficial marginal keratitis in the right eye and Terrien marginal degeneration in the left eye...
- Childhood mortality in a cohort treated with mass azithromycin for trachomaJeremy D Keenan
F I Proctor Foundation, San Francisco, CA, USA
Clin Infect Dis 52:883-8. 2011..Here, we monitor a large cohort in which almost 90% of individuals received azithromycin. We assess whether receiving treatment is associated with reduced all-cause and infectious childhood mortality...
- Retinopathy in nondiabetic persons with the metabolic syndrome: findings from the Third National Health and Nutrition Examination SurveyJeremy D Keenan
University of Illinois Eye and Ear Infirmary, Department of Ophthalmology and Visual Sciences, Chicago, Illinois, USA
Am J Ophthalmol 147:934-44, 944.e1-2. 2009..To study whether the metabolic syndrome is associated with retinopathy independent of the presence of diabetes...
- Granulomatous inflammation in juvenile idiopathic arthritis-associated uveitisJeremy D Keenan
University of Illinois Eye and Ear Infirmary, Chicago, Illnois, USA
J AAPOS 12:546-50. 2008..The uveitis that is associated with juvenile idiopathic arthritis (JIA) has typically been described as nongranulomatous. This study reports the prevalence of granulomatous disease in a population with JIA-associated uveitis...
- Clinical activity and polymerase chain reaction evidence of chlamydial infection after repeated mass antibiotic treatments for trachomaJeremy D Keenan
Department of Ophthalmology, University of California, San Francisco, CA, USA
Am J Trop Med Hyg 82:482-7. 2010....
- Adverse events after mass azithromycin treatments for trachoma in EthiopiaBerhan Ayele
The Carter Center, Addis Ababa, Ethiopia
Am J Trop Med Hyg 85:291-4. 2011..9% to 7.0% in children 1-9 years of age and from 17.0% to 18.7% in persons ≥ 10 years of age. Adverse events appeared to cluster by household and perhaps by village. Mass azithromycin distributions were well tolerated in this setting...
- Travel and implications for the elimination of trachoma in ethiopiaNeelima A Shah
Department of Public Health Sciences, University of California, Davis, California, USA
Ophthalmic Epidemiol 17:113-7. 2010..Reintroduction of infection could occur from the few remaining infected cases in a treated community or from outside the community. People traveling between villages might be responsible thus complicating the elimination of trachoma...
- Latrine promotion for trachoma: assessment of mortality from a cluster-randomized trial in EthiopiaTeshome Gebre
Carter Center Ethiopia, Addis Ababa, Ethiopia
Am J Trop Med Hyg 85:518-23. 2011..18, 95% CI = 0.89-1.58). Latrine promotion provided no additional effect on mortality in the context of an azithromycin distribution program (clinicaltrials.gov, #NCT00322972)...
- The fitness cost of antibiotic resistance in Streptococcus pneumoniae: insight from the fieldM Cyrus Maher
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 7:e29407. 2012..Observational studies have supported this, but due to ethical and practical considerations, it is rare to have experimental control over antibiotic prescription rates...
- The association between latrine use and trachoma: a secondary cohort analysis from a randomized clinical trialMeron Haile
Francis I Proctor Foundation, University of California, San Francisco, California The Carter Center, Addis Ababa, Ethiopia Departments of Ophthalmology and Epidemiology and Biostatistics, University of California, San Francisco, California The Carter Center, Atlanta, Georgia Institute for Global Health, University of California, San Francisco, California
Am J Trop Med Hyg 89:717-20. 2013..Specifically, for each 10% increase in latrine use, there was a 2.0% decrease (95% confidence interval = 0.2-3.9% decrease) in the community prevalence of ocular chlamydia over the subsequent year (P = 0.04)...
- How reliable are tests for trachoma?--a latent class approachCraig W See
F I Proctor Foundation, University of California San Francisco, San Francisco, California 94143 0412, USA
Invest Ophthalmol Vis Sci 52:6133-7. 2011..Latent class analysis (LCA) was performed to estimate the sensitivity and specificity of laboratory and clinical tests for trachoma in the absence of a gold standard...
- Association of conjunctival bacterial infection and female sex in cicatricial trachomaVicky Cevallos
Francis I Proctor Foundation, San Francisco, California 94143 0412, USA
Invest Ophthalmol Vis Sci 53:5208-12. 2012..To further characterize the microbiological profile of bacterial conjunctival infections in cicatricial trachoma, a conjunctival swabbing of adults in rural Ethiopia was performed...
- Reliability of measurements performed by community-drawn anthropometrists from rural EthiopiaBerhan Ayele
The Carter Center, Addis Ababa, Ethiopia
PLoS ONE 7:e30345. 2012..In this study, we trained individuals from rural communities in Ethiopia in anthropometry techniques and measured intra- and inter-observer reliability...
- Assessment of herd protection against trachoma due to repeated mass antibiotic distributions: a cluster-randomised trialJenafir I House
FI Proctor Foundation, University of California, San Francisco, USA
Lancet 373:1111-8. 2009..We assessed indirect protection against trachoma with mass azithromycin distributions...
- Comparison of annual versus twice-yearly mass azithromycin treatment for hyperendemic trachoma in Ethiopia: a cluster-randomised trialTeshome Gebre
The Carter Center, Addis Ababa, Ethiopia
Lancet 379:143-51. 2012..We aimed to compare the effect of annual versus twice-yearly distribution of azithromycin on infection with these strains...
- Efficacy of latrine promotion on emergence of infection with ocular Chlamydia trachomatis after mass antibiotic treatment: a cluster-randomized trialNicole E Stoller
F I Proctor Foundation, University of California San Francisco, USA
Int Health 3:75-84. 2011..0% and 25.0% respectively in the single treatment only arm. We were unable to detect a difference in the prevalence of ocular chlamydial infection in children due to latrine construction. ..
- Impact of mass azithromycin distribution on malaria parasitemia during the low-transmission season in Niger: a cluster-randomized trialBruce D Gaynor
F I Proctor Foundation, Department of Ophthalmology, Department of Epidemiology and Biostatistics, Institute for Global Health, Department of Medicine, University of California, San Francisco, California Programme National de Lutte Contre la Cecité Niamey, Niger Zinder Hospital, Zinder, Niger Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
Am J Trop Med Hyg 90:846-51. 2014..03). Mass distribution of azithromycin reduced malaria parasitemia 4-5 months after the intervention. The results suggest that drugs with antimalaria activity can have long-lasting impacts on malaria during periods of low transmission...
- When can antibiotic treatments for trachoma be discontinued? Graduating communities in three African countriesKathryn J Ray
F I Proctor Foundation, University of California, San Francisco, California, United States of America
PLoS Negl Trop Dis 3:e458. 2009..While this can be tested empirically, results will not be available for years. Here we use a mathematical model to predict results with different graduation strategies in three African countries...
- Association of community antibiotic consumption with clinically active trachoma in rural EthiopiaBerhan Ayele
The Carter Center Ethiopia, Bole K K, Kebele 05, H No 956, P O Box 13373, Addis Ababa, Ethiopia
Int Health 3:282-8. 2011..The low volume of macrolide consumption in this area suggests that selection for nasopharyngeal pneumococcal macrolide resistance after mass azithromycin treatments likely has little clinical significance. ..
- The clinical differentiation of bacterial and fungal keratitis: a photographic surveyCyril Dalmon
F I Proctor Foundation and Department of Ophthalmology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
Invest Ophthalmol Vis Sci 53:1787-91. 2012..The purpose of this study was to determine whether clinical signs of infectious keratitis can be used to identify the causative organism...
- Visual outcomes in treated bacterial keratitis: four years of prospective follow-upScott M McClintic
Department of Ophthalmology, University of California, San Francisco, San Francisco, California, United States
Invest Ophthalmol Vis Sci 55:2935-40. 2014..We described the change in visual acuity experienced by eyes successfully treated for bacterial keratitis...
- Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of expertsJeremy D Keenan
Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America Department of Ophthalmology, University of California, San Francisco, San Francisco, California, United States of America
PLoS Negl Trop Dis 7:e2562. 2013..We performed a survey of neglected tropical diseases experts to elicit their opinions on the role of mass drug administrations for the elimination of these infections...
- Reliability of trachoma clinical grading--assessing grading of marginal casesSalman A Rahman
F I Proctor Foundation, San Francisco, California, United States of America
PLoS Negl Trop Dis 8:e2840. 2014..Here, we confirm those results and assess performance of trainees on these borderline cases by calculating their reliability error, a measure derived from the decomposition of the Brier score...
- A mobile phone-based retinal camera for portable wide field imagingRobi N Maamari
F I Proctor Foundation and Department of Ophthalmology, University of California, San Francisco, California, USA
Br J Ophthalmol 98:438-41. 2014....
- Comparison of autophotomontage software programs in eyes with CMV retinitisJenny Chen
F I Proctor Foundation, San Francisco, California, USA
Invest Ophthalmol Vis Sci 52:9339-44. 2011..This study compares the quality of the mosaic products of three autophotomontage software programs, using digital fundus photographs of eyes with cytomegalovirus (CMV) retinitis...
- Topical fluoroquinolone use as a risk factor for in vitro fluoroquinolone resistance in ocular culturesRobert E Fintelmann
Francis I Proctor Foundation for Research in Ophthalmology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143 0412, USA
Arch Ophthalmol 129:399-402. 2011..To determine whether recent use of topical fluoroquinolones is a risk factor for in vitro fluoroquinolone resistance in Staphylococcus aureus ocular isolates...
- Practice patterns and opinions in the treatment of acanthamoeba keratitisCatherine E Oldenburg
F I Proctor Foundation, University of California, San Francisco, San Francisco, CA 94143 0944, USA
Cornea 30:1363-8. 2011..Management of acanthamoeba keratitis remains challenging for ophthalmologists. We conducted a survey of members of The Cornea Society to elicit expert opinions on the diagnosis and treatment of acanthamoeba keratitis...
- Predictors of matching in an ophthalmology residency programAllison R Loh
Department of Ophthalmology, University of California San Francisco, San Francisco, California 94121, USA
Ophthalmology 120:865-70. 2013..To examine the characteristics of US medical students applying for ophthalmology residency and to determine the predictors of matching...
- Efficacy and Safety of Antifungal Additives in Optisol-GS Corneal Storage MediumNoelle Layer
Department of Ophthalmology, University of California, San Francisco
JAMA Ophthalmol 132:832-7. 2014..Optisol-GS, the most common corneal storage medium in the United States, contains antibacterial but no antifungal supplementation. Most postkeratoplasty endophthalmitis and keratitis cases are now of a fungal origin...
- Accuracy and reliability of remote retinopathy of prematurity diagnosisMichael F Chiang
Department of Ophthalmology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Arch Ophthalmol 124:322-7. 2006..To determine the accuracy and reliability of retinopathy of prematurity (ROP) diagnosis using remote review of digital images by 3 masked ophthalmologist readers...