Paul E Keck

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi request reprint Long-term safety and efficacy of ziprasidone in subpopulations of patients with bipolar mania
    Paul E Keck
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Clin Psychiatry 70:844-51. 2009
  2. ncbi request reprint Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon
    Trisha Suppes
    Bipolar Disorder Research Program, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75390 9121, USA
    Arch Gen Psychiatry 62:1089-96. 2005
  3. ncbi request reprint Open-label aripiprazole in the treatment of acute bipolar depression: a prospective pilot trial
    Susan L McElroy
    Psychopharmacology Research Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States
    J Affect Disord 101:275-81. 2007
  4. ncbi request reprint Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study
    Lori L Altshuler
    Department of Psychiatry, Veterans Affairs Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, Los Angeles, CA, USA
    J Clin Psychiatry 70:450-7. 2009
  5. ncbi request reprint A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 9:426-34. 2007
  6. ncbi request reprint Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network
    Trisha Suppes
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9121, USA
    Int Clin Psychopharmacol 22:376-81. 2007
  7. ncbi request reprint Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placebo
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 68:1480-91. 2007
  8. ncbi request reprint Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trial
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, PO Box 670559, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:617-24. 2005
  9. ncbi request reprint Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study
    Lori L Altshuler
    Department of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, CA, USA
    J Clin Psychiatry 67:1551-60. 2006
  10. ncbi request reprint Ethnicity and first-rank symptoms in patients with psychosis
    Lesley M Arnold
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Schizophr Res 67:207-12. 2004

Collaborators

Detail Information

Publications68

  1. ncbi request reprint Long-term safety and efficacy of ziprasidone in subpopulations of patients with bipolar mania
    Paul E Keck
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Clin Psychiatry 70:844-51. 2009
    ..To evaluate long-term safety and efficacy of ziprasidone...
  2. ncbi request reprint Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon
    Trisha Suppes
    Bipolar Disorder Research Program, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75390 9121, USA
    Arch Gen Psychiatry 62:1089-96. 2005
    ..The prevalence of depressive symptoms co-occurring with hypomanic symptoms has not been quantified. Whether there is a greater likelihood for women to experience mixed symptoms has not been resolved...
  3. ncbi request reprint Open-label aripiprazole in the treatment of acute bipolar depression: a prospective pilot trial
    Susan L McElroy
    Psychopharmacology Research Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States
    J Affect Disord 101:275-81. 2007
    ..Increasing evidence indicates that some second-generation antipsychotics are efficacious in bipolar depression, but there are few data on this illness for the novel agent aripiprazole...
  4. ncbi request reprint Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study
    Lori L Altshuler
    Department of Psychiatry, Veterans Affairs Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, Los Angeles, CA, USA
    J Clin Psychiatry 70:450-7. 2009
    ..To assess long-term outcome in bipolar disorder, subjects were prospectively followed after receiving acute treatment for bipolar depression...
  5. ncbi request reprint A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 9:426-34. 2007
    ..The objective of this study was to compare sibutramine and topiramate as adjunctive treatments for psychotropic-associated weight gain in overweight or obese outpatients with BD...
  6. ncbi request reprint Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network
    Trisha Suppes
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9121, USA
    Int Clin Psychopharmacol 22:376-81. 2007
    ..No between-group differences in improvement were found. Adjunctive quetiapine may be useful as continuation treatment in bipolar populations with both pure depressive and cycling symptoms. Further controlled studies are warranted...
  7. ncbi request reprint Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placebo
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 68:1480-91. 2007
    ..Efficacy and tolerability of aripiprazole for relapse prevention in bipolar I disorder was, therefore, evaluated for 100 weeks...
  8. ncbi request reprint Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trial
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, PO Box 670559, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:617-24. 2005
    ..The response of 62 outpatients with DSM-IV bipolar disorders to open-label adjunctive zonisamide was evaluated in a prospective 8-week acute trial, followed by a 48-week continuation trial, conducted from June 2001 through May 2002...
  9. ncbi request reprint Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study
    Lori L Altshuler
    Department of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, CA, USA
    J Clin Psychiatry 67:1551-60. 2006
    ..Research examining this relationship in persons with bipolar disorder is rare. This study sought to evaluate the association between subsyndromal depressive symptoms and role functioning in subjects with bipolar disorder...
  10. ncbi request reprint Ethnicity and first-rank symptoms in patients with psychosis
    Lesley M Arnold
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Schizophr Res 67:207-12. 2004
    ..These findings indicate that psychotic symptom presentation should be evaluated in the context of other symptoms (e.g., affective symptoms) in diagnostic assessments in order to prevent misdiagnoses of schizophrenia...
  11. ncbi request reprint Topiramate in the long-term treatment of binge-eating disorder associated with obesity
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 65:1463-9. 2004
    ..This study assessed the long-term effectiveness and tolerability of topiramate in binge-eating disorder (BED) with obesity...
  12. ncbi request reprint Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0559, PO Box 670559, Cincinnati, OH 45267 0559, USA
    Arch Gen Psychiatry 62:851-8. 2005
    ..Alcohol-use disorders are common co-occurring conditions affecting bipolar patients, and this co-occurrence is negatively associated with outcome...
  13. doi request reprint Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression
    Mark A Frye
    Department of Psychiatry, Mayo Mood Clinic and Research Program, Mayo Clinic, 200 First St, S W, Rochester, MN 55901, USA
    Am J Psychiatry 166:164-72. 2009
    ..This study examined the correlates associated with treatment-emergent mania in patients receiving adjunctive antidepressant treatment for bipolar depression...
  14. ncbi request reprint Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 2341 Albert Sabin Way, Cincinnati, OH 45267, USA
    Arch Gen Psychiatry 64:57-64. 2007
    ..Cannabis use disorders commonly co-occur in bipolar disorder; however, the effects of cannabis abuse on outcome have been minimally studied...
  15. pmc Characterizing impulsivity in mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
    Bipolar Disord 11:41-51. 2009
    ....
  16. ncbi request reprint Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illness
    Paul E Keck
    Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Compr Psychiatry 44:263-9. 2003
    ..The lack of observable prognostic impact may have been, in part, due to the relatively high morbidity and poor functional outcome of a substantial portion of the total cohort...
  17. doi request reprint Treatment costs and health care utilization for patients with bipolar disorder in a large managed care population
    Jeff J Guo
    College of Pharmacy, University of Cincinnati Medical Center, Cincinnati, OH, USA
    Value Health 11:416-23. 2008
    ....
  18. doi request reprint Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial
    Anna I Guerdjikova
    Department of Psychiatry, University of Cincinnati College of Medicine, Lindner Center of HOPE, Mason, Ohio 45040, USA
    Int Clin Psychopharmacol 24:150-8. 2009
    ..As a result of an exceptionally high placebo response, it is likely that for efficacy measures except for body weight and metabolic indices, the study was incapable of detecting potentially clinically important drug-placebo difference...
  19. pmc Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder
    Caroline M Nievergelt
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0603, USA
    Am J Med Genet B Neuropsychiatr Genet 141:234-41. 2006
    ..However, the trends for ARNTL and PER3 are suggestive of their involvement in bipolar disorder and warrant further study in a larger sample...
  20. ncbi request reprint Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine and the Mental Health Care Line, Cincinnati, Ohio 45267 0559, USA
    Biol Psychiatry 60:1020-2. 2006
    ..The results of pilot trials suggest that omega-3 fatty acids may have efficacy in the treatment of mood symptoms in bipolar disorder...
  21. ncbi request reprint Comorbidity of fibromyalgia and psychiatric disorders
    Lesley M Arnold
    Women s Health Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45219, USA
    J Clin Psychiatry 67:1219-25. 2006
    ..To assess the co-occurrence of fibromyalgia with psychiatric disorders in participants of a fibromyalgia family study...
  22. ncbi request reprint The role of second-generation antipsychotic monotherapy in the rapid control of acute bipolar mania
    Paul E Keck
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    J Clin Psychiatry 66:5-11. 2005
    ..Therefore, selecting a second-generation antipsychotic requires consideration of how an agent's efficacy, onset of action, and adverse events profile influence its appropriateness for each patient...
  23. ncbi request reprint Ziprasidone in the treatment of acute bipolar mania: a three-week, placebo-controlled, double-blind, randomized trial
    Paul E Keck
    Department of Psychiatry, University of Cincinnati College of Medicine, OH 45627 0559, USA
    Am J Psychiatry 160:741-8. 2003
    ..The study evaluated the efficacy and tolerability of ziprasidone, compared with placebo, in the treatment of adult patients with acute bipolar mania...
  24. ncbi request reprint Are mood disorders and obesity related? A review for the mental health professional
    Susan L McElroy
    Psychopharmacology Research and Eating Disorders and Obesity Research and Treatment Programs, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 65:634-51, quiz 730. 2004
    ..We reviewed evidence regarding a possible relationship between mood disorders and obesity to better inform mental health professionals about their overlap...
  25. ncbi request reprint Citalopram in the treatment of binge-eating disorder: a placebo-controlled trial
    Susan L McElroy
    Division of Psychopharmacology Research and Eating Disorders, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 64:807-13. 2003
    ..Citalopram is a highly selective serotonin reuptake inhibitor antidepressant. The purpose of this study was to assess the efficacy and safety of citalopram in the treatment of binge-eating disorder...
  26. ncbi request reprint Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trial
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    J Clin Psychiatry 67:1897-906. 2006
    ..Binge eating disorder (BED) is associated with obesity. Zonisamide is a novel antiepileptic drug associated with weight loss. The purpose of this study was to evaluate zonisa-mide in the treatment of BED associated with obesity...
  27. ncbi request reprint Treatment costs related to bipolar disorder and comorbid conditions among Medicaid patients with bipolar disorder
    Jeff J Guo
    Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy and the Institute for the Study of Health, University of Cincinnati Academic Health Center, 3225 Eden Avenue, Cincinnati, OH 45267 0004, USA
    Psychiatr Serv 58:1073-8. 2007
    ..This study assessed costs among patients with bipolar disorder for treatment related to bipolar disorder and to comorbid conditions. Risk factors associated with costs were also assessed...
  28. ncbi request reprint Analyses of treatment-emergent mania with olanzapine/fluoxetine combination in the treatment of bipolar depression
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:611-6. 2005
    ..These subanalyses compare treatment-emergent mania rates in bipolar I depressed patients treated with olanzapine, placebo, or olanzapine/fluoxetine combination...
  29. ncbi request reprint Comorbidity of bipolar and eating disorders: distinct or related disorders with shared dysregulations?
    Susan L McElroy
    Psychopharmacology Research Program, University of Cincinnati College of Medicine, P O Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
    J Affect Disord 86:107-27. 2005
    ..The co-occurrence of bipolar and eating disorders, though of major clinical and public health importance, remains relatively unexamined...
  30. ncbi request reprint Maintenance efficacy of divalproex in the prevention of bipolar depression
    Laszlo Gyulai
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 28:1374-82. 2003
    ....
  31. ncbi request reprint Further evidence for linkage of bipolar disorder to chromosomes 6 and 17 in a new independent pedigree series
    Tiffany A Greenwood
    Department of Psychiatry, University of California, San Diego, CA, USA
    Bipolar Disord 14:71-9. 2012
    ..We now report the results of our genome-wide linkage analysis in an independent sample of 34 pedigrees segregating bipolar disorder...
  32. ncbi request reprint Risk of diabetes mellitus associated with atypical antipsychotic use among Medicaid patients with bipolar disorder: a nested case-control study
    Jeff J Guo
    College of Pharmacy, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0004, USA
    Pharmacotherapy 27:27-35. 2007
    ..To quantify the risk of diabetes mellitus associated with atypical antipsychotics compared with conventional antipsychotics in managed care Medicaid patients with bipolar disorder...
  33. ncbi request reprint Factors associated with medication adherence in African American and white patients with bipolar disorder
    David E Fleck
    Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:646-52. 2005
    ..The purpose of this study was to examine rates of medication nonadherence, self-perceived reasons for nonadherence, and attitudes associated with non-adherence in these ethnic groups...
  34. ncbi request reprint Lithium augmentation of topiramate for bipolar disorder with comorbid binge eating disorder and obesity
    Renu Kotwal
    Department of Psychiatry, Psychopharmacology Research Program, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Hum Psychopharmacol 21:425-31. 2006
    ..To evaluate the effectiveness of lithium augmentation of topiramate on mood symptoms, binge eating behavior, and body weight in obese bipolar patients with binge eating disorder (BED) seeking weight management...
  35. ncbi request reprint Defining and improving response to treatment in patients with bipolar disorder
    Paul E Keck
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    J Clin Psychiatry 65:25-9. 2004
    ..Psychoeducation for patients and families and interpersonal psychotherapy also can help prolong remission...
  36. doi request reprint Incidence of childhood-onset bipolar illness in the USA and Europe
    Robert M Post
    Department of Psychiatry, George Washington University, Washington, DC, USA
    Br J Psychiatry 192:150-1. 2008
    ..In the USA there was also twice the incidence of childhood adversity and genetic/familial risk for affective disorder. The findings deserve replication and further exploration...
  37. ncbi request reprint Pharmacologic treatment considerations in co-occurring bipolar and anxiety disorders
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    J Clin Psychiatry 67:8-15. 2006
    ..Anxiety disorders are among the most commonly co-occurring psychiatric syndromes with bipolar disorder. The presence of co-occurring anxiety disorders has important prognostic and treatment implications...
  38. ncbi request reprint A randomized, double-blind, placebo-controlled 26-week trial of aripiprazole in recently manic patients with bipolar I disorder
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    J Clin Psychiatry 67:626-37. 2006
    ..To investigate the safety and efficacy of aripiprazole in preventing relapse of a mood episode in recently manic- or mixed-episode patients with bipolar I disorder stabilized on aripiprazole...
  39. pmc Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder
    Tiffany A Greenwood
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
    J Affect Disord 150:1031-40. 2013
    ....
  40. ncbi request reprint Association of dopamine transporter gene variants with childhood ADHD features in bipolar disorder
    Tiffany A Greenwood
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
    Am J Med Genet B Neuropsychiatr Genet 162:137-45. 2013
    ..002, 0.007, and 8 × 10(-4), respectively). These data suggest that variants within DAT1 may predispose to a subtype of BD characterized by early prodromal features that include attentional deficits...
  41. ncbi request reprint Tiagabine in treatment refractory bipolar disorder: a clinical case series
    Trisha Suppes
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Bipolar Disord 4:283-9. 2002
    ..We sought to evaluate the effectiveness of tiagabine added to ongoing medication regimens in patients with bipolar disorder inadequately responsive to or intolerant of usual treatments...
  42. ncbi request reprint Relationship of open acute mania treatment to blinded maintenance outcome in bipolar I disorder
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Affect Disord 107:127-33. 2008
    ..No published studies have statistically evaluated the relationship between the outcomes in maintenance treatment and the principal acute agent...
  43. ncbi request reprint High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trial
    Anna I Guerdjikova
    Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Hum Psychopharmacol 23:1-11. 2008
    ..The purpose of this study was to evaluate the efficacy and safety of high-dose escitalopram in the treatment of binge-eating disorder (BED) associated with obesity...
  44. ncbi request reprint Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trial
    Susan L McElroy
    Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Am J Psychiatry 160:255-61. 2003
    ..Binge eating disorder is associated with obesity. Topiramate is an antiepileptic agent associated with weight loss. The objective of this study was to evaluate topiramate in the treatment of binge eating disorder associated with obesity...
  45. ncbi request reprint Atomoxetine in the treatment of binge-eating disorder: a randomized placebo-controlled trial
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    J Clin Psychiatry 68:390-8. 2007
    ..Binge-eating disorder (BED) is associated with obesity. Atomoxetine is a highly selective norepinephrine reuptake inhibitor associated with weight loss. The purpose of this study was to evaluate atomoxetine in the treatment of BED...
  46. ncbi request reprint New approaches in managing bipolar depression
    Paul E Keck
    Program Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 64:13-8. 2003
    ....
  47. ncbi request reprint Placebo response in binge eating disorder: a pooled analysis of 10 clinical trials from one research group
    Thomas J Blom
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Lindner Center of HOPE, Mason, OH, USA
    Eur Eat Disord Rev 22:140-6. 2014
    ..The aim of this study was to gain further understanding of placebo response in binge eating disorder...
  48. ncbi request reprint Examination of the clock gene Cryptochrome 1 in bipolar disorder: mutational analysis and absence of evidence for linkage or association
    Caroline M Nievergelt
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Psychiatr Genet 15:45-52. 2005
    ..Additional, more powerful, studies involving Cry1 and other circadian clock genes need to be tested before an association of circadian abnormalities with bipolar disorder can be excluded...
  49. ncbi request reprint Suggestive linkage of a chromosomal locus on 18p11 to cyclothymic temperament in bipolar disorder families
    Lynn M Evans
    Department of Psychiatry, Columbia University, New York, New York, USA
    Am J Med Genet B Neuropsychiatr Genet 147:326-32. 2008
    ..The temperament-based cyclothymic trait yielded a higher peak LOD score and a lower P-value than analyses using traditional, categorical phenotypes in a separate analysis including these same families...
  50. ncbi request reprint Long-term therapy of bipolar illness
    Paul E Keck
    University of Cincinnati College of Medicine, USA
    J Fam Pract . 2003
  51. doi request reprint Are bipolar mood symptoms affected by the phase of the menstrual cycle?
    Geetha Shivakumar
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9086, USA
    J Womens Health (Larchmt) 17:473-8. 2008
    ..We sought to examine the relationship between bipolar disorder and menstrual cycle-related mood changes. To our knowledge, this is one of the largest samples in the literature addressing this issue...
  52. ncbi request reprint Comorbidity of eating disorders with bipolar disorder and treatment implications
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    Bipolar Disord 8:686-95. 2006
    ..To review the scientific evidence examining the comorbidity among eating disorders and bipolar disorder (BD)...
  53. ncbi request reprint A retrospective chart review of intramuscular ziprasidone for agitation in children and adolescents on psychiatric units: prospective studies are needed
    Drew H Barzman
    Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, Cincinnati, Ohio 45229 3039, USA
    J Child Adolesc Psychopharmacol 17:503-9. 2007
    ..Our secondary objective was to examine demographic and clinical factors associated with treatment response...
  54. ncbi request reprint Psychiatric and metabolic characteristics of childhood versus adult-onset obesity in patients seeking weight management
    Anna I Guerdjikova
    Psychopharmacology Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
    Eat Behav 8:266-76. 2007
    ..Early recognition and attention to eating and mood dysregulation, including, but not limited to binge eating disorder and bulimia nervosa, in some persons, might help reduce their lifetime risk for obesity...
  55. doi request reprint Exposure to potentially dangerous drug-drug interactions involving antipsychotics
    Jeff Jianfei Guo
    Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of Cincinnati Medical Center, 3225 Eden Ave, Cincinnati, OH 45267, USA
    Psychiatr Serv 63:1080-8. 2012
    ..This study used a large state's Medicaid claims database to examine the proportion of patients exposed to such interactions and the risk factors associated with exposure...
  56. doi request reprint Suggestive evidence for linkage of ADHD features in bipolar disorder to chromosome 10p14
    Eun Jeong Joo
    Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
    Am J Med Genet B Neuropsychiatr Genet 153:260-8. 2010
    ..10p14, in particular may contain a locus for inattention in bipolar disorder. Quantitative dimensional phenotypes such as this may be useful for both mapping of genes and understanding the role of genes in bipolar disorder...
  57. ncbi request reprint Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trial
    Susan L McElroy
    Division of Clinical Neuroscience, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    J Clin Psychiatry 65:50-6. 2004
    ..It commonly co-occurs with obesity. Zonisamide is a novel antiepileptic drug associated with weight loss. The purpose of this study was to preliminarily assess zonisamide in the treatment of binge-eating disorder...
  58. ncbi request reprint Familiality of temperament in bipolar disorder: support for a genetic spectrum
    Lynn Evans
    Department of Psychiatry, UCSD, School of Medicine, University of California, 9500 Gilman Drive, La Jolla, CA 92093 0603, USA
    J Affect Disord 85:153-68. 2005
    ..We predicted that a gradient of scores would be observed from those with BP to those with major depression to unaffected relatives to controls...
  59. ncbi request reprint Phenomenology associated with age at onset in patients with bipolar disorder at their first psychiatric hospitalization
    Nick C Patel
    College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267 0004, USA
    Bipolar Disord 8:91-4. 2006
    ..To compare the clinical presentation of patients with early-onset (age <18 years) and typical-onset (age 20-30 years) bipolar disorder at the time of first hospitalization...
  60. ncbi request reprint Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 69:433-40. 2008
    ..Olanzapine is a second-generation antipsychotic with mood-stabilizing properties and antagonistic activity at several dopamine receptors. The purpose of this study was to evaluate olanzapine in the treatment of pathological gambling...
  61. ncbi request reprint Ethnic differences in maintenance antipsychotic prescription among adolescents with bipolar disorder
    Nick C Patel
    Department of Psychiatry, University of Cincinnati, and the General Clinical Research Center and Mental Health Service Line, Cincinnati Veterans Affairs Medical Center, Ohio 45267 0004, USA
    J Child Adolesc Psychopharmacol 15:938-46. 2005
    ..The aim of this study was to compare the longitudinal use of psychotropic medications in African-American and Caucasian adolescents with a diagnosis of bipolar disorder following their first psychiatric hospitalization...
  62. ncbi request reprint Long-term management strategies to achieve optimal function in patients with bipolar disorder
    Paul E Keck
    Department of Psychiatry, University of Cincinnati College of Medicine, and the General Clinical Research Center and Mental Health Care Line, Cincinnati Veterans Affairs Medical Center, Ohio 45267 0559, USA
    J Clin Psychiatry 67:19-24; discussion 36-42. 2006
    ..Substantial information is needed regarding the prevalence and causes of cognitive dysfunction in bipolar disorder, the effects of existing treatments on cognition, and long-term treatments to improve cognition and functioning...
  63. ncbi request reprint Emotional eating and emotional eating alternatives in subjects undergoing bariatric surgery
    Anna I Guerdjikova
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Obes Surg 17:1091-6. 2007
    ..The purpose of this study was to characterize emotional eating and its alternatives in obese patients undergoing bariatric surgery...
  64. ncbi request reprint A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole in patients with acute bipolar mania
    Paul E Keck
    Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, PO Box 670559, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 160:1651-8. 2003
    ..The authors compared the efficacy and safety of aripiprazole, a novel antipsychotic, to placebo for treatment of patients in an acute manic or mixed episode of bipolar disorder...
  65. ncbi request reprint The Texas implementation of medication algorithms update for treatment of bipolar I disorder
    Roy H Perlis
    Bipolar Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    J Clin Psychiatry 66:818-20. 2005
  66. ncbi request reprint Reproductive function and risk for PCOS in women treated for bipolar disorder
    Natalie L Rasgon
    Department of Psychiatry, Stanford School of Medicine, Palo Alto, CA, USA
    Bipolar Disord 7:246-59. 2005
    ..This study examined the reproductive function and prevalence of polycystic ovary syndrome (PCOS) in women with bipolar disorder taking antimanic medications...
  67. ncbi request reprint Predictors of response to treatment of acute bipolar manic episodes with divalproex sodium or placebo in 2 randomized, controlled, parallel-group trials
    Jeffrey A Welge
    Division of Clinical Neuroscience, Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati Veterans Affairs Medical Center, Cincinnati, OH, USA
    J Clin Psychopharmacol 24:607-12. 2004
    ..Stratification on the basis of these prognostic factors may improve the power of future trials for the treatment of acute mania and may help explain patient response to treatment...
  68. ncbi request reprint Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial
    Lesley M Arnold
    University of Cincinnati College of Medicine, Cincinnati, Ohio 45219, and Newton Wellesley Hospital, Newton, MA, USA
    Arthritis Rheum 56:1336-44. 2007
    ..To assess the efficacy and safety of gabapentin in patients with fibromyalgia...