- Phylodynamic analysis of the emergence and epidemiological impact of transmissible defective dengue virusesRuian Ke
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, California, United States of America
PLoS Pathog 9:e1003193. 2013..They also demonstrate that interactions between viral variants, such as complementation, can open new pathways to viral emergence...
- Modelling the activation of alkaline pH response transcription factor PacC in Aspergillus nidulans: involvement of a negative feedback loopRuian Ke
Department of Mathematics, Imperial College London, United Kingdom
J Theor Biol 326:11-20. 2013..Our work illustrates how mathematical models can be used to uncover regulatory mechanisms in the transcription regulation, and generate hypotheses that guide further laboratory investigations...
- An integrative model of ion regulation in yeastRuian Ke
Department of Mathematics, Imperial College London, London, United Kingdom
PLoS Comput Biol 9:e1002879. 2013..To conclude, this model serves as a powerful tool for both understanding the complex system-level properties of the highly coordinated adaptation process and generating further hypotheses for experimental investigation...
- Evolutionary analysis of human immunodeficiency virus type 1 therapies based on conditionally replicating vectorsRuian Ke
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California, USA
PLoS Comput Biol 8:e1002744. 2012....