G J Kazakia

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint New imaging technologies in the diagnosis of osteoporosis
    Galateia J Kazakia
    Musculoskeletal and Quantitative Imaging Research Group, UCSF Department of Radiology, 1700 4th Street, Suite 203, San Francisco, CA 94143, USA
    Rev Endocr Metab Disord 7:67-74. 2006
  2. pmc In vivo evaluation of the presence of bone marrow in cortical porosity in postmenopausal osteopenic women
    Janet Goldenstein
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA
    Ann Biomed Eng 38:235-46. 2010
  3. ncbi request reprint Automated high-resolution three-dimensional fluorescence imaging of large biological specimens
    G J Kazakia
    Orthopaedic Biomechanics Laboratory, Department of Mechanical Engineering, University of California, Berkeley, CA, USA
    J Microsc 225:109-17. 2007
  4. ncbi request reprint In vivo determination of bone structure in postmenopausal women: a comparison of HR-pQCT and high-field MR imaging
    Galateia J Kazakia
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, California 94158, USA
    J Bone Miner Res 23:463-74. 2008
  5. pmc Assessment of bone tissue mineralization by conventional x-ray microcomputed tomography: comparison with synchrotron radiation microcomputed tomography and ash measurements
    G J Kazakia
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, California 94158, USA
    Med Phys 35:3170-9. 2008
  6. pmc Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor
    G J Kazakia
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94107, USA
    Calcif Tissue Int 89:10-20. 2011
  7. pmc Quantitative assessment of bone tissue mineralization with polychromatic micro-computed tomography
    Andrew J Burghardt
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA
    Calcif Tissue Int 83:129-38. 2008
  8. pmc Variations in morphological and biomechanical indices at the distal radius in subjects with identical BMD
    Galateia J Kazakia
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, 185 Berry Street, San Francisco, CA, USA
    J Biomech 44:257-66. 2011
  9. pmc Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
    J Bone Miner Res 25:983-93. 2010
  10. ncbi request reprint A local adaptive threshold strategy for high resolution peripheral quantitative computed tomography of trabecular bone
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94158, USA
    Ann Biomed Eng 35:1678-86. 2007

Research Grants

Detail Information

Publications15

  1. ncbi request reprint New imaging technologies in the diagnosis of osteoporosis
    Galateia J Kazakia
    Musculoskeletal and Quantitative Imaging Research Group, UCSF Department of Radiology, 1700 4th Street, Suite 203, San Francisco, CA 94143, USA
    Rev Endocr Metab Disord 7:67-74. 2006
    ..The performance of these techniques in predicting osteoporotic fracture and assessing strength indices are discussed...
  2. pmc In vivo evaluation of the presence of bone marrow in cortical porosity in postmenopausal osteopenic women
    Janet Goldenstein
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA
    Ann Biomed Eng 38:235-46. 2010
    ..not containing marrow, varied highly between subjects. The results suggest that cortical pore spaces contain components of varying composition, and that there may be more than one mechanism for the development of cortical porosity...
  3. ncbi request reprint Automated high-resolution three-dimensional fluorescence imaging of large biological specimens
    G J Kazakia
    Orthopaedic Biomechanics Laboratory, Department of Mechanical Engineering, University of California, Berkeley, CA, USA
    J Microsc 225:109-17. 2007
    ..The three-dimensional nature of this highly automated and adaptable system has the potential to facilitate new diagnostic tools and techniques with application to a wide range of biological and medical research fields...
  4. ncbi request reprint In vivo determination of bone structure in postmenopausal women: a comparison of HR-pQCT and high-field MR imaging
    Galateia J Kazakia
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, California 94158, USA
    J Bone Miner Res 23:463-74. 2008
    ..Significant but moderate correlations and 2- to 4-fold discrepancies in parameter values were detected, suggesting that differences in acquisition and analysis must be considered when interpreting data from these imaging modalities...
  5. pmc Assessment of bone tissue mineralization by conventional x-ray microcomputed tomography: comparison with synchrotron radiation microcomputed tomography and ash measurements
    G J Kazakia
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, California 94158, USA
    Med Phys 35:3170-9. 2008
    ..Our results indicate that muCT mineralization measures are underestimated but well-correlated with SRmuCT and gravimetric data, particularly when volume fraction groups are considered individually...
  6. pmc Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor
    G J Kazakia
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94107, USA
    Calcif Tissue Int 89:10-20. 2011
    ..Our findings suggest that bone tissue quality may be an important contributor to increased fracture risk in fibrous dysplasia patients...
  7. pmc Quantitative assessment of bone tissue mineralization with polychromatic micro-computed tomography
    Andrew J Burghardt
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA
    Calcif Tissue Int 83:129-38. 2008
    ..80). In cortical bone specimens, the correlation was somewhat weaker when a global threshold was applied (R (2) = 0.67) compared to the local threshold method (R (2) = 0.78)...
  8. pmc Variations in morphological and biomechanical indices at the distal radius in subjects with identical BMD
    Galateia J Kazakia
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, 185 Berry Street, San Francisco, CA, USA
    J Biomech 44:257-66. 2011
    ..Overlap of these indices among osteoporotic status groups reflects the reported incidence of osteoporotic fracture in subjects classified as osteopenic or normal...
  9. pmc Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
    J Bone Miner Res 25:983-93. 2010
    ..The biomechanical significance of these structural differences increases with age for men and women and provides discriminatory information for menopause-related bone quality effects...
  10. ncbi request reprint A local adaptive threshold strategy for high resolution peripheral quantitative computed tomography of trabecular bone
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94158, USA
    Ann Biomed Eng 35:1678-86. 2007
    ....
  11. pmc Regional variations of gender-specific and age-related differences in trabecular bone structure of the distal radius and tibia
    Miki Sode
    Joint Graduate Group in Bioengineering, University of California, San Francisco, CA, USA
    Bone 46:1652-60. 2010
    ..Therefore, a combined approach of investigating the entire region, each subregion, and the cortical compartment may offer more complete information...
  12. pmc A longitudinal HR-pQCT study of alendronate treatment in postmenopausal women with low bone density: Relations among density, cortical and trabecular microarchitecture, biomechanics, and bone turnover
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA
    J Bone Miner Res 25:2558-71. 2010
    ..48, pā€‰<ā€‰.05). These findings suggest a more pronounced response to ALN in the tibia than in the radius, driven by trabecular and endocortical changes...
  13. doi request reprint Accuracy of volumetric bone mineral density measurement in high-resolution peripheral quantitative computed tomography
    Kiranjit Sekhon
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107, USA
    Bone 45:473-9. 2009
    ..Our results confirm that geometric and densitometric variations influence the accuracy of HR-pQCT vBMD(trab) measurements, and must be considered when interpreting data across populations or time-points...
  14. pmc Bone and cartilage demonstrate changes localized to bone marrow edema-like lesions within osteoarthritic knees
    G J Kazakia
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94107, USA
    Osteoarthritis Cartilage 21:94-101. 2013
    ..The aim of the present study was to evaluate bone structure and composition within bone marrow edema-like lesion (BMEL) regions associated with knee OA...
  15. pmc Automated simulation of areal bone mineral density assessment in the distal radius from high-resolution peripheral quantitative computed tomography
    A J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, QB3 Building, Suite 203, 1700 4th St, San Francisco, CA 94158, USA
    Osteoporos Int 20:2017-24. 2009
    ..This technique represents a useful reference to gauge the utility of novel 3D quantification methods applied to HR-pQCT in multi-center clinical studies and potentially negates the need for separate forearm DXA measurements...

Research Grants1

  1. CT & FTIR Assessment of Bone Struture and Composition
    Galateia Kazakia; Fiscal Year: 2007
    ....