Walter Kaye

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Neurobiology of anorexia and bulimia nervosa
    Walter Kaye
    University of California, San Diego, 8950 Villa La Jolla Drive, Suite C207, La Jolla, CA 92037, United States
    Physiol Behav 94:121-35. 2008
  2. ncbi request reprint Eating disorder symptomatology among ballet dancers
    Rebecca Ringham
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Int J Eat Disord 39:503-8. 2006
  3. ncbi request reprint Linkage analysis of anorexia nervosa incorporating behavioral covariates
    Bernie Devlin
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213 2593, USA
    Hum Mol Genet 11:689-96. 2002
  4. ncbi request reprint Genetic analysis of bulimia nervosa: methods and sample description
    Walter H Kaye
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Int J Eat Disord 35:556-70. 2004
  5. ncbi request reprint Neuroimaging studies in eating disorders
    Guido K Frank
    Department of Eating Disorders Research, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    CNS Spectr 9:539-48. 2004
  6. ncbi request reprint 5HT2A receptor binding is increased in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Biol Psychiatry 62:580-7. 2007
  7. ncbi request reprint Comorbidity of anxiety disorders with anorexia and bulimia nervosa
    Walter H Kaye
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara St, Suite 600, Iroquois Bldg, Pittsburgh, PA 15213, USA
    Am J Psychiatry 161:2215-21. 2004
  8. ncbi request reprint Serotonin alterations in anorexia and bulimia nervosa: new insights from imaging studies
    Walter H Kaye
    University of Pittsburgh, School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, United States
    Physiol Behav 85:73-81. 2005
  9. ncbi request reprint Brain imaging of serotonin after recovery from anorexia and bulimia nervosa
    Walter H Kaye
    University of Pittsburgh, School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, Iroquois Building, PA 15213, USA
    Physiol Behav 86:15-7. 2005
  10. ncbi request reprint The evaluation of brain activity in response to taste stimuli--a pilot study and method for central taste activation as assessed by event-related fMRI
    Guido K Frank
    Department of Psychiatry, Western Psychiatric Institute and Clinic, School of Medicine, University of Pittsburgh, Room 132, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Neurosci Methods 131:99-105. 2003

Collaborators

Detail Information

Publications60

  1. pmc Neurobiology of anorexia and bulimia nervosa
    Walter Kaye
    University of California, San Diego, 8950 Villa La Jolla Drive, Suite C207, La Jolla, CA 92037, United States
    Physiol Behav 94:121-35. 2008
    ..In summary, this article reviews findings in brain chemistry and neuroimaging that shed new light on understanding the psychopathology of these difficult and frustrating disorders...
  2. ncbi request reprint Eating disorder symptomatology among ballet dancers
    Rebecca Ringham
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Int J Eat Disord 39:503-8. 2006
    ..The current study sought to compare eating disorder symptomatology among ballet dancers and individuals with restricting anorexia nervosa (RAN), bulimia nervosa (BN), and no eating pathology...
  3. ncbi request reprint Linkage analysis of anorexia nervosa incorporating behavioral covariates
    Bernie Devlin
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213 2593, USA
    Hum Mol Genet 11:689-96. 2002
    ..50, P = 0.00035). By comparing our results to those implemented using more standard linkage methods, we find the covariates convey substantial information for the linkage analysis...
  4. ncbi request reprint Genetic analysis of bulimia nervosa: methods and sample description
    Walter H Kaye
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Int J Eat Disord 35:556-70. 2004
    ..The current study presents the clinical characteristics of this sample as well as a description of the study methodology...
  5. ncbi request reprint Neuroimaging studies in eating disorders
    Guido K Frank
    Department of Eating Disorders Research, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    CNS Spectr 9:539-48. 2004
    ..Taken together, these findings give promise for future investigations with the hope of delineating brain pathways that contribute to the etiology of EDs..
  6. ncbi request reprint 5HT2A receptor binding is increased in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Biol Psychiatry 62:580-7. 2007
    ..We examined 5HT(2A) receptor binding potential (BP) in impulsive subjects with BPD, with positron emission tomography neuroimaging with [(18)F] altanserin...
  7. ncbi request reprint Comorbidity of anxiety disorders with anorexia and bulimia nervosa
    Walter H Kaye
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara St, Suite 600, Iroquois Bldg, Pittsburgh, PA 15213, USA
    Am J Psychiatry 161:2215-21. 2004
    ....
  8. ncbi request reprint Serotonin alterations in anorexia and bulimia nervosa: new insights from imaging studies
    Walter H Kaye
    University of Pittsburgh, School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, United States
    Physiol Behav 85:73-81. 2005
    ..Alterations of these circuits may affect mood and impulse control as well as the motivating and hedonic aspects of feeding behavior. Such imaging studies may offer insights into new pharmacology and psychotherapy approaches...
  9. ncbi request reprint Brain imaging of serotonin after recovery from anorexia and bulimia nervosa
    Walter H Kaye
    University of Pittsburgh, School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, Iroquois Building, PA 15213, USA
    Physiol Behav 86:15-7. 2005
    ..Alterations of these circuits may affect mood and impulse control as well as the motivating and hedonic aspects of feeding behavior. Such imaging studies may offer insights into new pharmacology and psychotherapy approaches...
  10. ncbi request reprint The evaluation of brain activity in response to taste stimuli--a pilot study and method for central taste activation as assessed by event-related fMRI
    Guido K Frank
    Department of Psychiatry, Western Psychiatric Institute and Clinic, School of Medicine, University of Pittsburgh, Room 132, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Neurosci Methods 131:99-105. 2003
    ..We developed a standardized method for the assessment of brain activation in response to taste stimuli...
  11. ncbi request reprint Anxiolytic effects of acute tryptophan depletion in anorexia nervosa
    Walter H Kaye
    Department of Psychiatry, Anorexia and Bulimia Nervosa Research Module, University of Pittsburgh Medical School, 600 Iroquois Building, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Int J Eat Disord 33:257-67; discussion 268-70. 2003
    ..Dieting in AN, which serves to reduce plasma levels of tryptophan (TRP), may serve to reduce symptoms of dysphoric mood...
  12. doi request reprint New insights into symptoms and neurocircuit function of anorexia nervosa
    Walter H Kaye
    Eating Disorder Treatment and Research Program, Department of Psychiatry, University of California, San Diego, La Jolla Village Professional Center, 8950 Villa La Jolla Drive, Suite C 207, La Jolla, California 92037, USA
    Nat Rev Neurosci 10:573-84. 2009
    ..For example, altered insula activity could explain interoceptive dysfunction, and altered striatal activity might shed light on altered reward modulation in people with anorexia nervosa...
  13. ncbi request reprint Features associated with excessive exercise in women with eating disorders
    Hemal Shroff
    Department of Psychiatry, University of North Carolina, Chapel Hill, NC 27599 7160, and Center for Eating Disorders at Sheppard and Enoch Pratt Hospital, Towson, MD, USA
    Int J Eat Disord 39:454-61. 2006
    ..We explored features associated with excessive exercise across subtypes of eating disorders...
  14. ncbi request reprint Personality traits after recovery from eating disorders: do subtypes differ?
    Angela Wagner
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Int J Eat Disord 39:276-84. 2006
    ..We compared individuals recovered from anorexia (AN) and bulimia nervosa (BN) to determine characteristics that are shared by or distinguish eating disorder (ED) subtypes...
  15. pmc The genetics of anorexia nervosa collaborative study: methods and sample description
    Walter H Kaye
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania
    Int J Eat Disord 41:289-300. 2008
    ..Supported by National Institute of Mental Health (NIMH), this 12-site international collaboration seeks to identify genetic variants that affect risk for anorexia nervosa (AN)...
  16. ncbi request reprint Relationships between features associated with vomiting in purging-type eating disorders
    Lauren Reba
    Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 38:287-94. 2005
    ..We explored the relation between the symptom of vomiting and features of eating disorder course and severity, personality traits, and Axis I and II comorbidity in individuals with purging-type eating disorders...
  17. ncbi request reprint Altered brain activity in women recovered from bulimic-type eating disorders after a glucose challenge: a pilot study
    Guido K Frank
    Department of Psychiatry, School of Medicine, University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
    Int J Eat Disord 39:76-9. 2006
    ..Taste plays a role in the regulation of appetite and the purpose of the current study was to determine whether bulimic women have alterations in the physiologic response to the blind administration of glucose...
  18. doi request reprint Suicide attempts in anorexia nervosa
    Cynthia M Bulik
    Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
    Psychosom Med 70:378-83. 2008
    ..To explore prevalence and patterns of suicidal attempts in persons with anorexia nervosa (AN)...
  19. ncbi request reprint Positron emission tomography studies in eating disorders: multireceptor brain imaging, correlates with behavior and implications for pharmacotherapy
    Guido K Frank
    Department of Child and Adolescent Psychiatry, Center for Eating Disorders Research, School of Medicine, University of California San Diego, 92123, USA
    Nucl Med Biol 32:755-61. 2005
    ..These recognized receptors may now help us to move away from rather nonspecific treatment approaches in psychiatric research and clinic to the possibility of more syndrome- and symptom-specific treatment approaches...
  20. doi request reprint Influence of overanxious disorder of childhood on the expression of anorexia nervosa
    T J Raney
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 41:326-32. 2008
    ..This study investigates the prevalence of overanxious disorder (OAD) among women with AN and explores how OAD impacts AN symptoms and personality traits...
  21. ncbi request reprint Serotonin transporter binding after recovery from eating disorders
    Ursula F Bailer
    Western Psychiatric Institute and Clinic, University of Pittsburgh, Iroquois Building, Suite 600, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychopharmacology (Berl) 195:315-24. 2007
    ..Several lines of evidence suggest that altered serotonin (5-HT) function persists after recovery from anorexia nervosa (AN) and bulimia nervosa (BN)...
  22. ncbi request reprint Smoking in eating disorders
    Doris Anzengruber
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7160, USA
    Eat Behav 7:291-9. 2006
    ..The aim of this paper was to explore the patterns and prevalence of smoking behavior in 1,524 women from two of the multisite Price Foundation Genetic studies...
  23. ncbi request reprint Exaggerated 5-HT1A but normal 5-HT2A receptor activity in individuals ill with anorexia nervosa
    Ursula F Bailer
    Department of Psychiatry, Western Psychiatric Institute and Clinic, School of Medicine, Pittsburgh, University of Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 61:1090-9. 2007
    ..Because little is known about 5-HT receptor function in AN, positron emission tomography (PET) imaging with 5-HT receptor-specific radioligands was used to characterize 5-HT1A and 5-HT2A receptors...
  24. ncbi request reprint Altered insula response to taste stimuli in individuals recovered from restricting-type anorexia nervosa
    Angela Wagner
    Department of Psychiatry, School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neuropsychopharmacology 33:513-23. 2008
    ..These data provide the first evidence that individuals with AN process taste stimuli differently than controls, based on differences in neural activation patterns...
  25. ncbi request reprint Altered reward processing in women recovered from anorexia nervosa
    Angela Wagner
    University of Pittsburgh, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Am J Psychiatry 164:1842-9. 2007
    ..Building on previous findings of altered striatal dopamine binding in anorexia nervosa, the authors sought to assess the response of the anterior ventral striatum to reward and loss in this disorder...
  26. ncbi request reprint Impulse control disorders in women with eating disorders
    Fernando Fernandez-Aranda
    Department of Psychiatry, University Hospital of Bellvitge, Barcelona, Spain
    Psychiatry Res 157:147-57. 2008
    ..Untreated ICD may complicate recovery from eating disorders...
  27. ncbi request reprint Symptom profile of major depressive disorder in women with eating disorders
    Fernando Fernandez-Aranda
    Department of Psychiatry, University Hospital of Bellvitge, Barcelona, Spain
    Aust N Z J Psychiatry 41:24-31. 2007
    ..The temporal relation between EDs and MDD onset was analyzed to determine differences in the course and nature of MDD when experienced prior to versus after the onset of the ED...
  28. ncbi request reprint Patterns of menstrual disturbance in eating disorders
    Andréa Poyastro Pinheiro
    Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 40:424-34. 2007
    ..To describe menstrual disturbance in eating disorders (ED)...
  29. ncbi request reprint Regional cerebral blood flow after recovery from anorexia or bulimia nervosa
    Guido K Frank
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Int J Eat Disord 40:488-92. 2007
    ..Abnormalities of regional cerebral blood flow (rCBF) have been found in individuals who are ill with anorexia (AN) or bulimia nervosa (BN). Little is known about whether rCBF normalizes after recovery from AN and BN...
  30. ncbi request reprint The relation among perfectionism, obsessive-compulsive personality disorder and obsessive-compulsive disorder in individuals with eating disorders
    Katherine A Halmi
    New York Presbyterian Hospital Westchester Division, Weill Medical College of Cornell University, White Plains, New York, USA
    Int J Eat Disord 38:371-4. 2005
    ..Understanding the relation between these traits may enhance our ability to identify relevant behavioral endophenotypes for ED...
  31. pmc Linkage analysis of anorexia and bulimia nervosa cohorts using selected behavioral phenotypes as quantitative traits or covariates
    Silviu Alin Bacanu
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213 2593, USA
    Am J Med Genet B Neuropsychiatr Genet 139:61-8. 2005
    ..3); for covariate-based linkage analysis, five suggestive signals (for BMI at 4q13.1, for CM at 11p11.2 and 17q25.1, and for OBF at 17q25.1 and 15q26.2). Overlap between the two cohorts was minimal for substantial linkage signals...
  32. ncbi request reprint Altered 5-HT(2A) receptor binding after recovery from bulimia-type anorexia nervosa: relationships to harm avoidance and drive for thinness
    Ursula F Bailer
    Department of Psychiatry, School of Medicine, University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Neuropsychopharmacology 29:1143-55. 2004
    ..It is possible that subgenual cingulate findings are not specific for AN-BN, but may be related to the high incidence of lifetime major depressive disorder diagnosis in these subjects...
  33. ncbi request reprint Neurotransmitter and imaging studies in anorexia nervosa: new targets for treatment
    Nicole C Barbarich
    Anorexia and Bulimia Nervosa Research Module, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara Street, 600 Iroquois Building, Pittsburgh, PA 15213, USA
    Curr Drug Targets CNS Neurol Disord 2:61-72. 2003
    ..In summary, studies of pathophysiology are starting to nominate new candidates for treatment leading to the possibility of finding effective treatments for this often chronic or fatal disorder...
  34. ncbi request reprint Application of a latent class analysis to empirically define eating disorder phenotypes
    Pamela K Keel
    Department of Psychology, Harvard University, Cambridge, MA, USA
    Arch Gen Psychiatry 61:192-200. 2004
    ..Diagnostic criteria for eating disorders influence how we recognize, research, and treat eating disorders, and empirically valid phenotypes are required for revealing their genetic bases...
  35. ncbi request reprint A review of neuropeptide and neuroendocrine dysregulation in anorexia and bulimia nervosa
    Ursula F Bailer
    University of Pittsburgh Medical Center, Anorexia and Bulimia Nervosa Research Module, Western Psychiatric Institute and Clinic, 3811 O Hara Street, 600 Iroquois Building, Pittsburgh, PA 15213, USA
    Curr Drug Targets CNS Neurol Disord 2:53-9. 2003
    ....
  36. ncbi request reprint Alcohol use disorder comorbidity in eating disorders: a multicenter study
    Cynthia M Bulik
    Department of Psychiatry, University of North Carolina at Chapel Hill, 27599 7160, USA
    J Clin Psychiatry 65:1000-6. 2004
    ..Our aim was to explore the nature of the co-morbid relation between AUDs and eating disorders in a large and phenotypically well-characterized group of individuals...
  37. ncbi request reprint Use of nutritional supplements to increase the efficacy of fluoxetine in the treatment of anorexia nervosa
    Nicole C Barbarich
    Department of Psychiatry, University of Pittsburgh Medical School, Anorexia and Bulimia Nervosa Research Module, Pittsburgh, Pennsylvania 15213, USA
    Int J Eat Disord 35:10-5. 2004
    ..However, it may be effective in preventing relapse after weight restoration. The purpose of this study was to determine whether nutritional supplements could potentiate the effects of fluoxetine in underweight AN subjects...
  38. ncbi request reprint Personality characteristics of women before and after recovery from an eating disorder
    Kelly L Klump
    Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
    Psychol Med 34:1407-18. 2004
    ..This study compares personality characteristics among women who are ill with eating disorders, recovered from eating disorders, and those without eating or other Axis I disorder pathology...
  39. ncbi request reprint Symptom fluctuation in eating disorders: correlates of diagnostic crossover
    Federica Tozzi
    Department of Psychiatry, CB 7160, University of North Carolina at Chapel Hill, Neurosciences Hospital, Chapel Hill, NC 27599 7160l, USA
    Am J Psychiatry 162:732-40. 2005
    ..The authors identified factors that are associated with crossover from anorexia nervosa to bulimia nervosa and from bulimia nervosa to anorexia nervosa...
  40. ncbi request reprint Altered brain serotonin 5-HT1A receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [carbonyl11C]WAY-100635
    Ursula F Bailer
    Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 62:1032-41. 2005
    ..Previous studies have shown that women with anorexia nervosa (AN), when ill and after recovery, have alterations of serotonin (5-HT) neuronal activity and core eating disorder symptoms, such as anxiety...
  41. ncbi request reprint Normal brain tissue volumes after long-term recovery in anorexia and bulimia nervosa
    Angela Wagner
    Department of Psychiatry, Western Psychiatric Institute and Clinic, Presbyterian University Hospital, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Biol Psychiatry 59:291-3. 2006
    ..It is unclear whether such disturbances persist after recovery from an eating disorder...
  42. ncbi request reprint Reduced 5-HT2A receptor binding after recovery from anorexia nervosa
    Guido K Frank
    Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 52:896-906. 2002
    ..This study applied positron emission tomography (PET) to investigate the brain serotonin 2A (5HT2A) receptor, which could contribute to disturbances of appetite and behavior in AN...
  43. ncbi request reprint Neurobiology of anorexia nervosa: clinical implications of alterations of the function of serotonin and other neuronal systems
    Walter H Kaye
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Int J Eat Disord 37:S15-9; discussion S20-1. 2005
    ....
  44. ncbi request reprint Olanzapine treatment of anorexia nervosa: a retrospective study
    Amanda Malina
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Int J Eat Disord 33:234-7. 2003
    ..Recent reports raise the possibility that olanzapine, which commonly causes weight gain in non-eating-disordered subjects, assisted weight gain and mood during refeeding in anorexia nervosa (AN) patients...
  45. pmc Features associated with diet pill use in individuals with eating disorders
    Lauren Reba-Harrelson
    Department of Psychiatry, University of North Carolina at Chapel Hill, NC, United States
    Eat Behav 9:73-81. 2008
    ..In the eating disorder population, vigilant screening for diet pill use should be routine clinical practice...
  46. ncbi request reprint Obsessions and compulsions in anorexia nervosa subtypes
    Katherine A Halmi
    New York Presbyterian Hospital Westchester Division, Weill Medical College of Cornell University, 21 Bloomingdale Road, White Plains, NY 10605, USA
    Int J Eat Disord 33:308-19. 2003
    ..We examined the type and frequency of characteristic OCD obsessions and compulsions in a large sample of AN patients...
  47. ncbi request reprint Personality, perfectionism, and attitudes toward eating in parents of individuals with eating disorders
    D Blake Woodside
    Department of Psychiatry, Toronto General Hospital, Toronto, Ontario, Canada
    Int J Eat Disord 31:290-9. 2002
    ..This study compares personality and eating-related traits in parents of probands with eating disorders, with age-band matched healthy normal controls...
  48. pmc Significant linkage on chromosome 10p in families with bulimia nervosa
    Cynthia M Bulik
    Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, USA
    Am J Hum Genet 72:200-7. 2003
    ..92 and 3.39, meet the widely accepted criterion for genomewide significance. Another region on 14q meets the criterion for genomewide suggestive linkage, with MLSs of 1.97 (full sample) and 1.75 (subset) at 62 centimorgans from p-ter...
  49. doi request reprint Temporal patterns of recovery across eating disorder subtypes
    Ann Von Holle
    Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
    Aust N Z J Psychiatry 42:108-17. 2008
    ..To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN)...
  50. ncbi request reprint Pain perception in recovered bulimia nervosa patients
    Daniel Stein
    Sheba Medical Center, 21Tel Hashomer, Israel
    Int J Eat Disord 34:331-6. 2003
    ..Decreased pain sensitivity is found in individuals who are ill with bulimia nervosa (BN). The purpose of this study is to determine whether altered pain perception persists after recovery from bulimia nervosa (RBN)...
  51. ncbi request reprint The relationship of body dysmorphic disorder and eating disorders to obsessive-compulsive disorder
    Katharine A Phillips
    Brown Medical School, Providence, RI, USA
    CNS Spectr 12:347-58. 2007
    ..Additional research is needed on the relationship of BDD and eating disorders to OCD, including studies that directly compare them to OCD in a variety of domains, including phenomenology, family history, neurobiology, and etiology...
  52. ncbi request reprint Increased dopamine D2/D3 receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [11c]raclopride
    Guido K Frank
    Department of Psychiatry, Western Psychiatric Institute and Clinic, School of Medicine, University of California San Diego, California, USA
    Biol Psychiatry 58:908-12. 2005
    ..Several lines of evidence support the possibility that disturbances of dopamine (DA) function could contribute to alterations of weight, feeding, motor activity, and reward in anorexia nervosa (AN)...
  53. ncbi request reprint Association of multiple DRD2 polymorphisms with anorexia nervosa
    Andrew W Bergen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7236, USA
    Neuropsychopharmacology 30:1703-10. 2005
    ..Genetically transmitted variation in D2 dopamine receptor expression mediated by functional polymorphisms affecting transcription and translation efficiency may play a role in vulnerability to AN...
  54. ncbi request reprint Features associated with laxative abuse in individuals with eating disorders
    Federica Tozzi
    Department of Psychiatry, University of North Carolina at Chapel Hill, 1st floor Neurosciences Hospital, CB 7160, Chapel Hill, North Carolina 27599 7160, USA
    Psychosom Med 68:470-7. 2006
    ..We explored the extent to which laxative abuse was associated with specific psychopathological features across eating disorder subtypes...
  55. ncbi request reprint Neural correlates of habituation to taste stimuli in healthy women
    Angela Wagner
    University of Pittsburgh, School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, PA 15213, USA
    Psychiatry Res 147:57-67. 2006
    ..By contrast, for sequential blocks, both stimuli produced habituation in taste-related brain regions. These data suggest that habituation patterns in healthy subjects may depend on frequency and regularity of stimulus administration...
  56. ncbi request reprint An open trial of olanzapine in anorexia nervosa
    Nicole C Barbarich
    Department of Psychiatry, University of Pittsburgh Medical School, Anorexia and Bulimia Nervosa Research Module, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 65:1480-2. 2004
    ..Recent reports raise the possibility that olanzapine can assist weight gain and improve behavioral symptoms during refeeding in anorexia nervosa...
  57. ncbi request reprint Personality in men with eating disorders
    D Blake Woodside
    Program for Eating Disorders, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada
    J Psychosom Res 57:273-8. 2004
    ..This study compares personality variables of men with eating disorders to women with eating disorders...
  58. ncbi request reprint Report of the National Institutes of Health workshop on overcoming barriers to treatment research in anorexia nervosa
    W Stewart Agras
    Department of Psychiatry, Stanford University School of Medicine, Stanford, California, USA
    Int J Eat Disord 35:509-21. 2004
    ..The goals of this workshop were to discuss the stages of illness and illness severity, pharmacologic interventions, psychological interventions, and methodologic considerations...
  59. pmc Selection of eating-disorder phenotypes for linkage analysis
    Cynthia M Bulik
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Am J Med Genet B Neuropsychiatr Genet 139:81-7. 2005
    ..Linkage results appear in a subsequent report. Our report lays out a systematic roadmap for utilizing a rich set of phenotypes for genetic analyses, including the selection of linkage methods paired to those phenotypes...
  60. ncbi request reprint Sucrose activates human taste pathways differently from artificial sweetener
    Guido K W Frank
    University of Colorado at Denver and Health Sciences Center, Department of Psychiatry, The Children s Hospital, Aurora, CO 80045, USA
    Neuroimage 39:1559-69. 2008
    ..This could have important implications on how effective artificial sweeteners are in their ability to substitute sugar intake...

Research Grants5

  1. PET IMAGING AND SEROTONIN LIGANDS IN EATING DISORDERS
    Walter Kaye; Fiscal Year: 2005
    ....
  2. Serotonin - A Trait Disturbance in Anorexia Nervosa?
    Walter Kaye; Fiscal Year: 2007
    ..This is a resubmissien of a cemDetina renewal of MH46001. ..
  3. Family Therapy and Fluoxetine in the Treatment of Adolescent Anorexia Nervosa
    Walter Kaye; Fiscal Year: 2007
    ..From the public health perspective, development of effective treatments for adolescents will reduce the morbidity, mortality, and high costs associated with chronic AN. ..