D I Kaufer

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Beyond the cholinergic hypothesis: the effect of metrifonate and other cholinesterase inhibitors on neuropsychiatric symptoms in Alzheimer's disease
    D Kaufer
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Dement Geriatr Cogn Disord 9:8-14. 1998
  2. ncbi request reprint Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory
    D I Kaufer
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    J Neuropsychiatry Clin Neurosci 12:233-9. 2000
  3. ncbi request reprint Psychotic symptoms in Alzheimer's disease are not associated with more severe neuropathologic features
    R A Sweet
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Int Psychogeriatr 12:547-58. 2000
  4. pmc Cortical cholinergic denervation is associated with depressive symptoms in Parkinson's disease and parkinsonian dementia
    N I Bohnen
    Department of Neurology, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, USA
    J Neurol Neurosurg Psychiatry 78:641-3. 2007
  5. pmc Cholinesterase inhibitor treatment alters the natural history of Alzheimer's disease
    O L Lopez
    Alzheimer s Disease Research Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Neurol Neurosurg Psychiatry 72:310-4. 2002
  6. pmc Right prosubiculum amyloid plaque density correlates with anosognosia in Alzheimer's disease
    G A Marshall
    Department of Neurology, University of Pittsburgh, Pennsylvania, USA
    J Neurol Neurosurg Psychiatry 75:1396-400. 2004
  7. ncbi request reprint Long-term care in dementia: patients and caregivers
    D I Kaufer
    Departments of Neurology and Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Clin Cornerstone 3:52-62. 2001
  8. ncbi request reprint White matter hyperintensities and cortical acetylcholinesterase activity in parkinsonian dementia
    G A Marshall
    Department of Neurology, University of Pittsburgh and Veterans Affairs Medical Center, Pittsburgh, PA, USA
    Acta Neurol Scand 113:87-91. 2006
  9. pmc Degree of inhibition of cortical acetylcholinesterase activity and cognitive effects by donepezil treatment in Alzheimer's disease
    N I Bohnen
    University of Pittsburgh, Liliane S Kaufmann Building, Suite 811, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Neurol Neurosurg Psychiatry 76:315-9. 2005
  10. ncbi request reprint Cognitive correlates of cortical cholinergic denervation in Parkinson's disease and parkinsonian dementia
    N I Bohnen
    Department of Radiology, University of Pittsburgh Medical School, PA 15213, USA
    J Neurol 253:242-7. 2006

Detail Information

Publications10

  1. ncbi request reprint Beyond the cholinergic hypothesis: the effect of metrifonate and other cholinesterase inhibitors on neuropsychiatric symptoms in Alzheimer's disease
    D Kaufer
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Dement Geriatr Cogn Disord 9:8-14. 1998
    ..The nature of non-cognitive symptom responses to AChE inhibitor therapy and their potential impact on caregivers is discussed...
  2. ncbi request reprint Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory
    D I Kaufer
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    J Neuropsychiatry Clin Neurosci 12:233-9. 2000
    ..The NPI-Q provides a brief, reliable, informant-based assessment of neuropsychiatric symptoms and associated caregiver distress that may be suitable for use in general clinical practice...
  3. ncbi request reprint Psychotic symptoms in Alzheimer's disease are not associated with more severe neuropathologic features
    R A Sweet
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Int Psychogeriatr 12:547-58. 2000
    ..The association of AD+P with a more rapidly progressive course of AD appears to be mediated by a neuropathologic process other than increased severity of plaque and tangle formation...
  4. pmc Cortical cholinergic denervation is associated with depressive symptoms in Parkinson's disease and parkinsonian dementia
    N I Bohnen
    Department of Neurology, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, USA
    J Neurol Neurosurg Psychiatry 78:641-3. 2007
    ..To investigate the relationship between ratings of depressive symptoms and in vivo cortical acetylcholinesterase (AChE) activity in subjects with Parkinson's disease (PD) and parkinsonian dementia (PDem)...
  5. pmc Cholinesterase inhibitor treatment alters the natural history of Alzheimer's disease
    O L Lopez
    Alzheimer s Disease Research Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Neurol Neurosurg Psychiatry 72:310-4. 2002
    ..To describe the effect of cholinesterase inhibitors (CEIs) on the natural course of Alzheimer's disease (AD)...
  6. pmc Right prosubiculum amyloid plaque density correlates with anosognosia in Alzheimer's disease
    G A Marshall
    Department of Neurology, University of Pittsburgh, Pennsylvania, USA
    J Neurol Neurosurg Psychiatry 75:1396-400. 2004
    ..There is an association between impaired awareness and frontal-executive cognitive deficits. Anosognosia is also correlated with decreased metabolism in the right hemisphere, particularly in frontal lobe regions...
  7. ncbi request reprint Long-term care in dementia: patients and caregivers
    D I Kaufer
    Departments of Neurology and Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Clin Cornerstone 3:52-62. 2001
    ..This article reviews salient aspects of long-term care for patients with AD and other dementias, highlighting the vital and varied roles of physicians in managing these chronic brain disorders...
  8. ncbi request reprint White matter hyperintensities and cortical acetylcholinesterase activity in parkinsonian dementia
    G A Marshall
    Department of Neurology, University of Pittsburgh and Veterans Affairs Medical Center, Pittsburgh, PA, USA
    Acta Neurol Scand 113:87-91. 2006
    ..To investigate the relationship between the severity of white matter hyperintensities (WMH) and cortical acetylcholinesterase (AChE) activity in parkinsonian dementia (PDem)...
  9. pmc Degree of inhibition of cortical acetylcholinesterase activity and cognitive effects by donepezil treatment in Alzheimer's disease
    N I Bohnen
    University of Pittsburgh, Liliane S Kaufmann Building, Suite 811, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Neurol Neurosurg Psychiatry 76:315-9. 2005
    ..To determine in vivo cortical acetylcholinesterase (AChE) activity and cognitive effects in subjects with mild Alzheimer's disease (AD, n = 14) prior to and after 12 weeks of donepezil therapy...
  10. ncbi request reprint Cognitive correlates of cortical cholinergic denervation in Parkinson's disease and parkinsonian dementia
    N I Bohnen
    Department of Radiology, University of Pittsburgh Medical School, PA 15213, USA
    J Neurol 253:242-7. 2006
    ..14, ns). We conclude that cortical cholinergic denervation in PD and parkinsonian dementia is associated with decreased performance on tests of attentional and executive functioning...