RICHARD ALAN KASLOW

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians
    Rakhi Malhotra
    Department of Epidemiology, University of Alabama at Birmingham UAB, Birmingham, AL, USA
    Retrovirology 8:22. 2011
  2. pmc Risk factors for acquisition of hepatitis C virus infection: a case series and potential implications for disease surveillance
    L J Yee
    Department of Medicine, Division of Gastroenterology Hepatology UAB Liver Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, 35294, USA
    BMC Infect Dis 1:8. 2001
  3. pmc Polymorphisms in HLA class I genes associated with both favorable prognosis of human immunodeficiency virus (HIV) type 1 infection and positive cytotoxic T-lymphocyte responses to ALVAC-HIV recombinant canarypox vaccines
    R A Kaslow
    Department of Epidemiology and International Health, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Virol 75:8681-9. 2001
  4. ncbi request reprint President's address
    Richard A Kaslow
    Department of Epidemiology, University of Alabama SOPH, Birmingham, AL 35294 0222, USA
    Ann Epidemiol 13:545-8. 2003
  5. ncbi request reprint Influence of host genetic variation on susceptibility to HIV type 1 infection
    Richard A Kaslow
    Department of Epidemiology, University of Alabama at Birmingham, AL 35294, USA
    J Infect Dis 191:S68-77. 2005
  6. ncbi request reprint Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection
    L J Yee
    Program on the Epidemiology of Infection and Immunity, Department of Epidemiology and International Health, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
    Genes Immun 1:386-90. 2000
  7. ncbi request reprint Interleukin 10 polymorphisms as predictors of sustained response in antiviral therapy for chronic hepatitis C infection
    L J Yee
    Program in Epidemiology of Infection and Immunity, Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 35294 0022, USA
    Hepatology 33:708-12. 2001
  8. ncbi request reprint Molecular typing of human leukocyte antigen and related polymorphisms following whole genome amplification
    W Shao
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Tissue Antigens 64:286-92. 2004
  9. pmc Interleukin 18 and human immunodeficiency virus type I infection in adolescents and adults
    W Song
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Clin Exp Immunol 144:117-24. 2006
  10. ncbi request reprint Conserved extended haplotypes of the major histocompatibility complex: further characterization
    M T Dorak
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Genes Immun 7:450-67. 2006

Detail Information

Publications60

  1. pmc Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians
    Rakhi Malhotra
    Department of Epidemiology, University of Alabama at Birmingham UAB, Birmingham, AL, USA
    Retrovirology 8:22. 2011
    ....
  2. pmc Risk factors for acquisition of hepatitis C virus infection: a case series and potential implications for disease surveillance
    L J Yee
    Department of Medicine, Division of Gastroenterology Hepatology UAB Liver Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, 35294, USA
    BMC Infect Dis 1:8. 2001
    ..We examined risk factors for acquiring HCV in patients who were referred to two tertiary care centers and enrolled in an antiviral therapy protocol...
  3. pmc Polymorphisms in HLA class I genes associated with both favorable prognosis of human immunodeficiency virus (HIV) type 1 infection and positive cytotoxic T-lymphocyte responses to ALVAC-HIV recombinant canarypox vaccines
    R A Kaslow
    Department of Epidemiology and International Health, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Virol 75:8681-9. 2001
    ..This proof of principle that class I an alleles modulate both processes has implications for development of HIV-1 and presumably other vaccines...
  4. ncbi request reprint President's address
    Richard A Kaslow
    Department of Epidemiology, University of Alabama SOPH, Birmingham, AL 35294 0222, USA
    Ann Epidemiol 13:545-8. 2003
  5. ncbi request reprint Influence of host genetic variation on susceptibility to HIV type 1 infection
    Richard A Kaslow
    Department of Epidemiology, University of Alabama at Birmingham, AL 35294, USA
    J Infect Dis 191:S68-77. 2005
    ..Teasing apart the effects in both donors and recipients has been and will continue to be quite difficult...
  6. ncbi request reprint Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection
    L J Yee
    Program on the Epidemiology of Infection and Immunity, Department of Epidemiology and International Health, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
    Genes Immun 1:386-90. 2000
    ..Polymorphisms in the TNF alpha promoter appear to be associated with variability in the histological severity of chronic hepatitis C infection...
  7. ncbi request reprint Interleukin 10 polymorphisms as predictors of sustained response in antiviral therapy for chronic hepatitis C infection
    L J Yee
    Program in Epidemiology of Infection and Immunity, Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 35294 0022, USA
    Hepatology 33:708-12. 2001
    ..In conclusion, homozygosity for -592A, -819T or the extended haplotype (108bp) - (-2575T) - (-2763C) - (-1082A) - (-819T) - (-592A) is associated with SR to IFN + R...
  8. ncbi request reprint Molecular typing of human leukocyte antigen and related polymorphisms following whole genome amplification
    W Shao
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Tissue Antigens 64:286-92. 2004
    ..General population genetic analyses provided additional evidence that WGA may represent a reliable and simple approach to securing ample genomic DNA for typing HLA, MICA, and related variants...
  9. pmc Interleukin 18 and human immunodeficiency virus type I infection in adolescents and adults
    W Song
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Clin Exp Immunol 144:117-24. 2006
    ..Collectively, these findings suggest that circulating IL-18 rather than the IL18 genotype may provide a useful biomarker for HIV-1-related events or outcomes...
  10. ncbi request reprint Conserved extended haplotypes of the major histocompatibility complex: further characterization
    M T Dorak
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Genes Immun 7:450-67. 2006
    ..These results portray the MHC where lineages containing non-HLA and HLA variants in linkage disequilibrium may operate in concert and can guide more thorough design and interpretation of HLA-disease relationships...
  11. doi request reprint Associated factors and impact of myocarditis in patients with SLE from LUMINA, a multiethnic US cohort (LV). [corrected]
    M Apte
    Department of Epidemiology, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA
    Rheumatology (Oxford) 47:362-7. 2008
    ..To examine the factors associated with myocarditis and its impact on disease outcomes in SLE patients...
  12. ncbi request reprint Decrease of cytomegalovirus replication in human immunodeficiency virus infected-patients after treatment with highly active antiretroviral therapy
    C E O'Sullivan
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham AL 39294 0006, USA
    J Infect Dis 180:847-9. 1999
    ..1 to 1.7 at 385 days with a commensurate rise in median CD4 T cells to 166/mm3. Immune reconstitution secondary to HAART results in a significant and progressive decline in CMV viremia in the absence of specific anti-CMV therapy...
  13. pmc Mortality risk associated with rheumatoid arthritis in a prospective cohort of older women: results from the Iowa Women's Health Study
    T R Mikuls
    Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, 35294, USA
    Ann Rheum Dis 61:994-9. 2002
    ..To determine whether rheumatoid arthritis (RA) is associated with excess mortality among older women...
  14. ncbi request reprint Pharmacogenomic perspectives of chronic hepatitis C virus (HCV) infection
    J Tang
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Pharmacogenomics J 4:171-4. 2004
  15. ncbi request reprint TAPI polymorphisms in several human ethnic groups: characteristics, evolution, and genotyping strategies
    J Tang
    Division of Geographic Medicine, Department of Medicine, University of Alabama at Birmingham, Alabama 35294 0022, USA
    Hum Immunol 62:256-68. 2001
    ..Characterization of TAP1 polymorphisms allowed the design of a PCR-based genotyping scheme that targeted 7 SNP sites and required 2 separate genotyping techniques...
  16. ncbi request reprint New TAP2 polymorphisms in Africans
    J Tang
    Department of Medicine, University of Alabama at Birmingham, 35294, USA
    Tissue Antigens 51:556-62. 1998
    ..Analyses of the relationship between the 374Thr-467Ile segment and the nearby markers in DQB1 and DRB1 suggested the existence of a unique extended haplotype related to these newly identified variants...
  17. ncbi request reprint Genotyping TAP2 variants in North American Caucasians, Brazilians, and Africans
    J Tang
    Program in Epidemiology of Infection and Immunity, School of Public Health, Department of Medicine, University of Alabama at Birmingham, 35294, USA
    Genes Immun 2:32-40. 2001
    ..Such complexity of TAP2 polymorphisms, in the form of SNPs as well as alleles, is likely to complicate the analyses of disease associations and haplotype structures in the HLA class II region...
  18. ncbi request reprint Novel alleles at the lymphotoxin alpha (LTalpha) locus mark extended HLA haplotypes in native Africans
    J Tang
    Program in Epidemiology of Infection and Immunity, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 39294, USA
    Hum Immunol 62:269-78. 2001
    ..These findings suggest a preferential expansion of the human TNFc dinucleotide (CT/AG) repeat sequence and further imply the existence of two extended MHC lineages that have not been disrupted by recombinations...
  19. ncbi request reprint CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection
    W Shao
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Genes Immun 8:224-31. 2007
    ....
  20. ncbi request reprint MICA intron 1 sequences of conserved extended HLA haplotypes: implications for sequencing-based typing
    W Shao
    Department of Epidemiology, University of Alabama at Birmingham, USA
    Genes Immun 5:371-4. 2004
    ..Being neutral ones, the intron 1 and STR polymorphisms appeared to mark the ancestral lineages better than the coding region polymorphisms...
  21. pmc Interleukin (IL)-2 and IL-12 responses to Chlamydia trachomatis infection in adolescents
    C Wang
    Department of Epidemiology, University of Alabama at Birmingham, 35294 0007, USA
    Clin Exp Immunol 142:548-54. 2005
    ..From these findings we infer that increased IL-12 and decreased IL-2, observed commonly during mucosal inflammation, are important features of mucosal immune defence against C. trachomatis infection...
  22. ncbi request reprint HIV type 1 superinfection with a dual-tropic virus and rapid progression to AIDS: a case report
    Geoffrey S Gottlieb
    Division of Allergy and Infectious Diseases, School of Medicine, University of Washington, Seattle, WA 98195, USA
    Clin Infect Dis 45:501-9. 2007
    ..The occurrence of human immunodeficiency virus type 1 (HIV-1) superinfection has implications for vaccine development and our understanding of HIV pathogenesis and transmission...
  23. ncbi request reprint CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides
    Anju Bansal
    Department of Medicine, University of Alabama at Birmingham, 20th Street South, Birmingham, AL 35294, USA
    AIDS 19:241-50. 2005
    ..To understand the mechanisms underlying the differential targeting of T-cell responses during HIV-1 disease progression...
  24. pmc Human leukocyte antigen B58 supertype and human immunodeficiency virus type 1 infection in native Africans
    Aleksandr Lazaryan
    Department of Epidemiology, University of Alabama at Birmingham, AL 35294, USA
    J Virol 80:6056-60. 2006
    ..As presently defined, B58s alleles cannot be considered uniformly protective against HIV/AIDS in every population...
  25. ncbi request reprint Human leukocyte antigen and cytokine gene variants as predictors of recurrent Chlamydia trachomatis infection in high-risk adolescents
    Chengbin Wang
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabam 35294 0022, USA
    J Infect Dis 191:1084-92. 2005
    ....
  26. ncbi request reprint HLA-B, -DRB1/3/4/5, and -DQB1 gene polymorphisms in human immunodeficiency virus-related Kaposi's sarcoma
    M Tevfik Dorak
    Department of Epidemiology and Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    J Med Virol 76:302-10. 2005
    ..Alternatively, the relationship might hold a clue to the predilection of KS for men because that haplotype harbors the mutant form of the 21-hydroxylase gene...
  27. ncbi request reprint Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme
    Jianming Tang
    Department of Medicine, University of Alabama at Birmingham, 1665 University Boulevard, RPHB Room 220A, Birmingham, AL 35294 0022, USA
    Cancer Epidemiol Biomarkers Prev 14:2040-4. 2005
    ..B*07 and the B*07-Cw*07 haplotype are much more common in Caucasians than other ethnic groups in the U.S., which may partially explain the higher incidence of glioblastoma multiforme in Caucasians...
  28. ncbi request reprint A case-control study to examine HLA haplotype associations in patients with posttreatment chronic Lyme disease
    Mark S Klempner
    Boston University School of Medicine and Boston Medical Center, Massachusetts 02118, USA
    J Infect Dis 192:1010-3. 2005
    ..No strong association between posttreatment chronic Lyme disease and any class II allele or genotype was found...
  29. pmc Human leukocyte antigen class I genotypes in relation to heterosexual HIV type 1 transmission within discordant couples
    Jianming Tang
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Immunol 181:2626-35. 2008
    ..Thus, HLA class I gene products not only mediate HIV-1 pathogenesis and evolution but also influence heterosexual HIV-1 transmission...
  30. pmc Immunogenetic correlates of Neisseria gonorrhoeae infection in adolescents
    William M Geisler
    Department of Medicine, School of Medicine, University of Alabama at Birmingham, 1665 University Boulevard, RPHB Room 220A, Birmingham, AL 35294 0022, USA
    Sex Transm Dis 35:656-61. 2008
    ..Understanding host factors modulating immunity to Neisseria gonorrhoeae infection may benefit work on vaccine development...
  31. pmc Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients
    Paul A Goepfert
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Exp Med 205:1009-17. 2008
    ..In addition to their direct implications for HIV-1 vaccine design, these data suggest that CTL-induced viral polymorphisms and their associated in vivo viral fitness costs could have a significant impact on HIV-1 pathogenesis...
  32. doi request reprint Clinical outcome of HIV-infected antiretroviral-naive patients with discordant immunologic and virologic responses to highly active antiretroviral therapy
    Ruimin Tan
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Acquir Immune Defic Syndr 47:553-8. 2008
    ..The prognostic significance of a response to highly active antiretroviral therapy (HAART) that is immunologically and virologically discordant is not well understood...
  33. ncbi request reprint Cohort- and time-specific associations of CTLA4 genotypes with HIV-1 disease progression
    Wenshuo Shao
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    AIDS 20:1583-90. 2006
    ..We examined the relationships between common CTLA4 variants and several outcomes of HIV-1 infection in adults and adolescents...
  34. pmc Immunological control of chronic HIV-1 infection: HLA-mediated immune function and viral evolution in adolescents
    Anju Bansal
    Department of Medicine, University of Alabama at Birmingham, Alabama, USA
    AIDS 21:2387-97. 2007
    ..Differential protein targeting by HIV-specific CD8 T cells is associated with disparate plasma viral loads; however, it is unclear if the quality of these responses differs depending upon the specificity of the targeted epitopes...
  35. ncbi request reprint Interleukin-10 gene (IL10) polymorphisms and human papillomavirus clearance among immunosuppressed adolescents
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, 1665 University Boulevard, RPHB Room 220A, Birmingham, AL 35294 0022, USA
    Cancer Epidemiol Biomarkers Prev 16:1626-32. 2007
    ....
  36. ncbi request reprint Epidemiological and genetic correlates of incident Chlamydia trachomatis infection in North American adolescents
    William M Geisler
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    J Infect Dis 190:1723-9. 2004
    ..These findings suggest that antigen presentation in adaptive immune responses may serve as a major factor in effective control of C. trachomatis infection. The underlying mechanisms remain to be experimentally elucidated...
  37. pmc Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early HIV-1 RNA concentration in plasma, and later disease progression
    Jianming Tang
    Division of Geographic Medicine, Department of Medicine, School of Medicine, Program in Epidemiology of Infection and Immunity, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Virol 76:662-72. 2002
    ....
  38. pmc Comprehensive analysis of class I and class II HLA antigens and chronic hepatitis B virus infection
    Chloe L Thio
    Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Virol 77:12083-7. 2003
    ..The associations with class I alleles are consistent with a previously implicated role for CD8-mediated cytolytic-T-cell response in determining the outcome of an acute HBV infection...
  39. ncbi request reprint Influence of human leukocyte antigen-B22 alleles on the course of human immunodeficiency virus type 1 infection in 3 cohorts of white men
    M Tevfik Dorak
    Department of Epidemiology, University of Alabama at Birmingham, Alabama, USA
    J Infect Dis 188:856-63. 2003
    ..This finding may have greater implications for Asians, because the marker frequency for B22 is higher among Asians than among whites (approximately 10% vs. approximately 4%)...
  40. ncbi request reprint Cross-reactive CD8+ T cell epitopes identified in US adolescent minorities
    Steffanie Sabbaj
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Acquir Immune Defic Syndr 33:426-38. 2003
    ..Frequent recognition of several of these CTL epitopes in persons of diverse racial backgrounds bodes well for the development of a broadly reactive HIV-1 vaccine...
  41. ncbi request reprint The complexity of HLA class II (DRB1, DQB1, DM) associations with disseminated Mycobacterium avium complex infection among HIV-1-seropositive whites
    Eknath Naik
    Department of Epidemiology and Biostatistics, University of South Florida, Tampa, Florida, USA
    J Acquir Immune Defic Syndr 33:140-5. 2003
    ....
  42. ncbi request reprint Association of polymorphisms in human leukocyte antigen class I and transporter associated with antigen processing genes with resistance to human immunodeficiency virus type 1 infection
    Chenglong Liu
    School of Public Health, University of California, Los Angeles, CA 90095, USA
    J Infect Dis 187:1404-10. 2003
    ..In multivariate logistic analysis, only the A*0205 subgroup (OR, 5.56; 95% CI, 1.34-23.10; P=.018) and the TAP2 Ala665 (OR, 2.22; 95% CI, 1.28-3.84; P=.005) were associated with resistance...
  43. ncbi request reprint Host genetic profiles predict virological and immunological control of HIV-1 infection in adolescents
    Jianming Tang
    Department of Medicine, University of Alabama at Birmingham, AL 39294 0022, USA
    AIDS 16:2275-84. 2002
    ..To evaluate the correlation between host genetic profiles and virological and immunological outcomes among HIV-1-seropositive participants from the Reaching for Excellence in Adolescent Care and Health (REACH) cohort...
  44. pmc Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1
    Jianming Tang
    Department of Medicine, University of Alabama at Birmingham, Alabama 35294, USA
    J Virol 76:8276-84. 2002
    ..1% of those with the highest (>100,000) VL. Clear differential distribution of HLA profiles according to level of viremia suggests important host genetic contribution to the pattern of immune control and escape during HIV-1 infection...
  45. ncbi request reprint CCR2 and CCR5 genotypes in HIV type 1-infected adolescents: limited contributions to variability in plasma HIV type 1 RNA concentration in the absence of antiretroviral therapy
    Jianming Tang
    Division of Geographic Medicine, Department of Medicine, Schools of Public Health and Medicine, 1665 University Blvd, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    AIDS Res Hum Retroviruses 18:403-12. 2002
    ..001). Thus, among the major CCR2-CCR5 haplotypes/genotypes in chronically infected and predominantly African-American adolescents, only the E/E genotype appeared to influence early host-virus equilibration...
  46. ncbi request reprint T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles
    Anju Bansal
    Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    AIDS Res Hum Retroviruses 19:1017-26. 2003
    ..Hence host genetic variation among different racial groups may have less impact on the utility of candidate HIV-1 vaccines than previously suspected...
  47. ncbi request reprint HLA-DRB1 and -DQB1 alleles and haplotypes in Zambian couples and their associations with heterosexual transmission of HIV type 1
    Jianming Tang
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Infect Dis 189:1696-704. 2004
    ..Overall, associations of HLA class II polymorphisms with both HIV transmission and acquisition are not as readily interpretable as are effects reported for other loci...
  48. ncbi request reprint HLA allele sharing and HIV type 1 viremia in seroconverting Zambians with known transmitting partners
    Jianming Tang
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    AIDS Res Hum Retroviruses 20:19-25. 2004
    ..However, correlation of virus loads in seroconverters with those of their known index partners (adjusted Pearson r = 0.21, p = 0.03) did imply that viral characteristics can independently contribute to variability in plasma virus load...
  49. ncbi request reprint Lack of associations between HLA class II alleles and resistance to HIV-1 infection among white, non-Hispanic homosexual men
    Chenglong Liu
    School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
    J Acquir Immune Defic Syndr 37:1313-7. 2004
    ..Other genetic factors in the HLA class II-TAP region of the major histocompatibility complex might be involved...
  50. ncbi request reprint Cytokine and chemokine gene polymorphisms among ethnically diverse North Americans with HIV-1 infection
    Chengbin Wang
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Acquir Immune Defic Syndr 35:446-54. 2004
    ....
  51. ncbi request reprint HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination
    Chengbin Wang
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Hepatology 39:978-88. 2004
    ..In conclusion, DRB1*07 (or a closely linked allele) and immunoregulatory cytokine gene polymorphisms correlate with variable immune response to recombinant HBV vaccines...
  52. ncbi request reprint Transmission of HIV-1 and HLA-B allele-sharing within serodiscordant heterosexual Zambian couples
    M Tevfik Dorak
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Lancet 363:2137-9. 2004
    ..23, 95% CI 1.52-3.26, p<0.0001). Selective pressure by HLA-B alleles on transmitted viruses accords with current understanding of the effect of B locus polymorphism in HIV-1 and perhaps other infections...
  53. ncbi request reprint The impact of host genetics on HIV infection and disease progression in the era of highly active antiretroviral therapy
    Jianming Tang
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    AIDS 17:S51-60. 2003
  54. ncbi request reprint Correlates of resistance to HIV-1 infection in homosexual men with high-risk sexual behaviour
    Fransje A Koning
    Department of Clinical Viro Immunology, Sanquin Research at CLB and Landsteiner Laboratory of the Academic Medical Centre, University of Amsterdam, The Netherlands
    AIDS 18:1117-26. 2004
    ..To investigate possible correlates of HIV resistance in participants from the Amsterdam Cohort of Homosexual men who have remained HIV seronegative despite high-risk sexual behaviour...
  55. ncbi request reprint C-C chemokine receptor 2 and C-C chemokine receptor 5 genotypes in patients treated for chronic hepatitis C virus infection
    M Tevfik Dorak
    Department of Epidemiology and International Health, School of Public Health, Comprehensive Cancer Center, University of Alabama at Birmingham, 35294 0022, USA
    Immunol Res 26:167-75. 2002
    ..016). Differential receptor expression due to E/E homozygosity in HCV infection remains to be confirmed...
  56. ncbi request reprint Association of CTLA4 polymorphisms with sustained response to interferon and ribavirin therapy for chronic hepatitis C virus infection
    Leland J Yee
    Program in Epidemiology of Infection and Immunity, Department of Epidemiology, School of Public Health, University of Alabama at Birmingham Liver Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Infect Dis 187:1264-71. 2003
    ..0095) and the -318C-49G haplotype. CTLA4 49G in exon 1 alone and in a haplotype with -318C promoter is associated with sustained IFNalpha+R response in white patients with HCV genotype 1 infection...
  57. pmc Co-infection with HIV and hepatitis C virus in former plasma/blood donors: challenge for patient care in rural China
    Han Zhu Qian
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    AIDS 20:1429-35. 2006
    ..Illegal commercial plasma donation in the late 1980s and early 1990s caused blood-borne infections in China...
  58. ncbi request reprint Haplotype inference for present-absent genotype data using previously identified haplotypes and haplotype patterns
    Yun Joo Yoo
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Bioinformatics 23:2399-406. 2007
    ....
  59. pmc Factors associated with delayed initiation of HIV medical care among infected persons attending a southern HIV/AIDS clinic
    Christopher S Krawczyk
    University of Alabama, Birmingham Schools of Public Health and Medicine, Birmingham, AL, USA
    South Med J 99:472-81. 2006
    ..Despite the proven benefits conferred by early human immunodeficiency virus (HIV) diagnosis and presentation to care, delays in HIV medical care are common; these delays are not fully understood, especially in the southern United States...
  60. pmc Cytotoxic T-lymphocyte antigen 4 gene and recovery from hepatitis B virus infection
    Chloe L Thio
    Department of Medicine, Johns Hopkins Medical Institutions, 1503 E Jefferson Street, Baltimore, MD 21231, USA
    J Virol 78:11258-62. 2004
    ..32, P = 0.04). These data suggest that CTLA4 influences recovery from HBV infection, which is consistent with the emerging role of T regulatory cells in the pathogenesis of disease...

Research Grants17

  1. Host Genetic Epidemiology in HIV-1-Discordant African Couples and Other Cohorts
    RICHARD ALAN KASLOW; Fiscal Year: 2010
    ....
  2. Chromosome 6p21-24 Markers in HIV-Related Kaposi Sarcoma
    Richard Kaslow; Fiscal Year: 2006
    ..Beyond its impact on HIV-KS, the work should contribute valuable information for population genetics of this genomic region. ..
  3. Genetic Factors in the Epidemiology of HIV-1 Infection
    Richard Kaslow; Fiscal Year: 2005
    ..abstract_text> ..
  4. GENETIC FACTORS IN THE EPIDEMIOLOGY OF HIV1 INFECTION
    Richard Kaslow; Fiscal Year: 2000
    ....
  5. Host Genetic Epidemiology in HIV-1-Discordant African Couples and Other Cohorts
    RICHARD ALAN KASLOW; Fiscal Year: 2010
    ....