Thomas L Kash

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc The role of biogenic amine signaling in the bed nucleus of the stria terminals in alcohol abuse
    Thomas Louis Kash
    Bowles Center for Alcohol Studies, School of Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
    Alcohol 46:303-8. 2012
  2. pmc Central neuropeptide Y modulates binge-like ethanol drinking in C57BL/6J mice via Y1 and Y2 receptors
    Angela M Sparrow
    Department of Psychology, University of North Carolina, Chapel Hill, NC, USA
    Neuropsychopharmacology 37:1409-21. 2012
  3. pmc Distinct extended amygdala circuits for divergent motivational states
    Joshua H Jennings
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Nature 496:224-8. 2013
  4. pmc Presynaptic inhibition of gamma-aminobutyric acid release in the bed nucleus of the stria terminalis by kappa opioid receptor signaling
    Chia Li
    Curriculum in Neurobiology, School of Medicine, University of North Carolina Chapel Hill, NC 27599, USA
    Biol Psychiatry 71:725-32. 2012
  5. pmc Alcohol effects on synaptic transmission in periaqueductal gray dopamine neurons
    Chia Li
    Curriculum in Neurobiology, University of North Carolina Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA
    Alcohol 47:279-87. 2013
  6. pmc Corticotropin releasing factor signaling in the central amygdala is recruited during binge-like ethanol consumption in C57BL/6J mice
    Emily G Lowery-Gionta
    Department of Psychology, Bowles Center for Alcohol Studies, and Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina 27599 3270, USA
    J Neurosci 32:3405-13. 2012
  7. pmc Chemogenetic inactivation of ventral hippocampal glutamatergic neurons disrupts consolidation of contextual fear memory
    Hu Zhu
    Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA
    Neuropsychopharmacology 39:1880-92. 2014
  8. pmc Chronic stress alters neuropeptide Y signaling in the bed nucleus of the stria terminalis in DBA/2J but not C57BL/6J mice
    Kristen E Pleil
    Bowles Center for Alcohol Studies and Department of Pharmacology, School of Medicine, University of North Carolina Chapel Hill, 104 Manning Driv, Chapel Hill, NC 27599, USA
    Neuropharmacology 62:1777-86. 2012

Research Grants

Collaborators

  • Garret D Stuber
  • Jennifer A Rinker
  • Sheryl S Moy
  • Kristen E Pleil
  • Chia Li
  • Emily G Lowery-Gionta
  • Hu Zhu
  • Joshua H Jennings
  • Alice M Stamatakis
  • Benjamin R Cox
  • Gretchen M Sprow
  • Ana M Jijon
  • Angela M Sparrow
  • Montserrat Navarro
  • Todd E Thiele
  • Daniel J Urban
  • Bryan L Roth
  • Nora M McCall
  • Randall L Ung
  • Dennis R Sparta
  • Alberto J Lopez
  • Nora McCall
  • Jose Peña Bravo
  • Alberto Lopez
  • Jose Pena
  • Bradford B Lowell
  • Linh Vong
  • Steven Busan

Detail Information

Publications8

  1. pmc The role of biogenic amine signaling in the bed nucleus of the stria terminals in alcohol abuse
    Thomas Louis Kash
    Bowles Center for Alcohol Studies, School of Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
    Alcohol 46:303-8. 2012
    ....
  2. pmc Central neuropeptide Y modulates binge-like ethanol drinking in C57BL/6J mice via Y1 and Y2 receptors
    Angela M Sparrow
    Department of Psychology, University of North Carolina, Chapel Hill, NC, USA
    Neuropsychopharmacology 37:1409-21. 2012
    ..The current data suggest that Y1R agonists and Y2R antagonists may be useful for curbing and/or preventing binge drinking, protecting vulnerable individuals from progressing to the point of ethanol dependence...
  3. pmc Distinct extended amygdala circuits for divergent motivational states
    Joshua H Jennings
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Nature 496:224-8. 2013
    ..These data demonstrate that functionally opposing BNST to VTA circuits regulate rewarding and aversive motivational states, and may serve as a crucial circuit node for bidirectionally normalizing maladaptive behaviours...
  4. pmc Presynaptic inhibition of gamma-aminobutyric acid release in the bed nucleus of the stria terminalis by kappa opioid receptor signaling
    Chia Li
    Curriculum in Neurobiology, School of Medicine, University of North Carolina Chapel Hill, NC 27599, USA
    Biol Psychiatry 71:725-32. 2012
    ..This suggests that KOR activation in this region may play a role in the regulation of emotional behaviors. To date, however, there has been no investigation of the ability of KOR to modulate synaptic transmission in the BNST...
  5. pmc Alcohol effects on synaptic transmission in periaqueductal gray dopamine neurons
    Chia Li
    Curriculum in Neurobiology, University of North Carolina Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA
    Alcohol 47:279-87. 2013
    ..These data add to a growing body of literature that points to alcohol having both region-dependent and cell-type dependent effects on function...
  6. pmc Corticotropin releasing factor signaling in the central amygdala is recruited during binge-like ethanol consumption in C57BL/6J mice
    Emily G Lowery-Gionta
    Department of Psychology, Bowles Center for Alcohol Studies, and Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina 27599 3270, USA
    J Neurosci 32:3405-13. 2012
    ..We hypothesize that plastic changes in CRF signaling develop with repeated binge-like drinking episodes, contributing to the transition to dependence...
  7. pmc Chemogenetic inactivation of ventral hippocampal glutamatergic neurons disrupts consolidation of contextual fear memory
    Hu Zhu
    Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA
    Neuropsychopharmacology 39:1880-92. 2014
    ..Significantly, we found that selective inactivation of ventral but not dorsal glutamatergic hippocampal neurons suppressed the synaptic consolidation of contextual memory. ..
  8. pmc Chronic stress alters neuropeptide Y signaling in the bed nucleus of the stria terminalis in DBA/2J but not C57BL/6J mice
    Kristen E Pleil
    Bowles Center for Alcohol Studies and Department of Pharmacology, School of Medicine, University of North Carolina Chapel Hill, 104 Manning Driv, Chapel Hill, NC 27599, USA
    Neuropharmacology 62:1777-86. 2012
    ....

Research Grants1

  1. The Role of Serotonin in Alcohol-Withdrawal Induced Anxiety
    Thomas L Kash; Fiscal Year: 2010
    ..Further, these studies may provide insight as to how to develop more useful treatments for alcoholism and anxiety disorders. ..