Research Topics
| Jordan F KarpSummaryAffiliation: University of Pittsburgh Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Addressing both depression and pain in late life: the methodology of the ADAPT studyJordan F Karp
Departments of Psychiatry, University of Pittsburgh and University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Pain Med 13:405-18. 2012..To describe the methodology of the first NIH-funded clinical trial for seniors with comorbid depression and chronic low back pain...
The relationship between pain and mental flexibility in older adult pain clinic patientsJordan F Karp
Intervention Research Center and Advanced Center for Intervention and Services Research for Late Life Mood Disorders, University of Pittburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Pain Med 7:444-52. 2006..Mental flexibility, memory, and information-processing speed may be particularly vulnerable in the aging brain. We investigated the effects of persistent pain on these cognitive domains among community-dwelling, nondemented older adults...
Use of the late-life function and disability instrument to assess disability in major depressionJordan F Karp
Advanced Center for Intervention and Services Research for Late Life Mood Disorders, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Courier Office 100 North Bellefield Avenue, Room 766, Pittsburgh, PA 15213, USA
J Am Geriatr Soc 57:1612-9. 2009....
Persistent pain biases item response on the Geriatric Depression Scale (GDS): preliminary evidence for validity of the GDS-PAINJordan F Karp
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Pain Med 9:33-43. 2008..We hypothesized that in older adults with persistent pain, items of the Geriatric Depression Scale (GDS) would evidence DIF based on presence or intensity of pain...
Duloxetine and care management treatment of older adults with comorbid major depressive disorder and chronic low back pain: results of an open-label pilot studyJordan F Karp
Advanced Center for Intervention and Services Research for Late Life Mood Disorders, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Int J Geriatr Psychiatry 25:633-42. 2010....
Pain predicts longer time to remission during treatment of recurrent depressionJordan F Karp
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Clin Psychiatry 66:591-7. 2005..We hypothesized that greater pain and somatic scores prior to treatment with imipramine and interpersonal psychotherapy would predict a slowed time to remission from depression...
Body pain and treatment response in late-life depressionJordan F Karp
Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Geriatr Psychiatry 13:188-94. 2005..They hypothesized that higher levels of body pain would predict a longer time to and lower likelihood of response, and increased levels of suicidal ideation...
Relationship of variability in residual symptoms with recurrence of major depressive disorder during maintenance treatmentJordan F Karp
Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 161:1877-84. 2004....
Outcomes of late-life anxiety disorders during 32 weeks of citalopram treatmentStephen Blank
Intervention Research Center for Late-Life Mood Disorders, The Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Clin Psychiatry 67:468-72. 2006..CONCLUSIONS: In this 32-week study of citalopram for elderly persons with anxiety disorders, 60% responded. Those who received a full course of treatment experience significant improvements in quality of life and sleep quality...
Treating depression to remission in older adults: a controlled evaluation of combined escitalopram with interpersonal psychotherapy versus escitalopram with depression care managementCharles F Reynolds
Department of Psychiatry, Advanced Center for Interventions and Services Research for Late Life Mood Disorders, Clinical Trials Management Unit, University of Pittsburgh School of Medicine, PA, USA
Int J Geriatr Psychiatry 25:1134-41. 2010....
Comorbid anxiety disorder in late life depression: association with memory decline over four yearsAlison K DeLuca
The Intervention Research Center for Late-Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Int J Geriatr Psychiatry 20:848-54. 2005..The data also suggest that anxiety disorders with an onset later in life may be associated with cognitive impairment, although further study is needed to confirm this finding...
Pain interference impacts response to treatment for anxiety disordersCARRIE FARMER TEH
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Depress Anxiety 26:222-8. 2009..Anxiety disorders and pain are commonly comorbid, though little is known about the effect of pain on the course and treatment of anxiety...
Predicting 6-week treatment response to escitalopram pharmacotherapy in late-life major depressive disorderRamin Saghafi
Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, USA
Int J Geriatr Psychiatry 22:1141-6. 2007..This study aims to characterize sociodemographic, clinical, and neuropsychologic correlates of full, partial, and non-response to escitalopram monotherapy of unipolar MDD in later life...
The impact of pain and depression on recovery after coronary artery bypass graftingNatalia E Morone
Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Psychosom Med 72:620-5. 2010..To describe the relationship between pain and depression on recovery after coronary artery bypass grafting (CABG)...
Anxiety impairs depression remission in partial responders during extended treatment in late-lifeAdam Greenlee
Advanced Center for Intervention and Services Research for Late Life Mood Disorders, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
Depress Anxiety 27:451-6. 2010..This study characterizes the effect of anxiety on remission during extended treatment for partial responders...
Rescue pharmacotherapy with duloxetine for selective serotonin reuptake inhibitor nonresponders in late-life depression: outcome and tolerabilityJordan F Karp
Western Psychiatric Institute and Clinic, Advanced Center for Interventions and Services Research for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
J Clin Psychiatry 69:457-63. 2008....
Somatic symptoms in late-life anxiety: treatment issuesEric J Lenze
Intervention Research Center for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
J Geriatr Psychiatry Neurol 18:89-96. 2005..However, additional treatment and integrated approaches are likely to be necessary for many such individuals...
Maintenance treatment of depression in old age: a randomized, double-blind, placebo-controlled evaluation of the efficacy and safety of donepezil combined with antidepressant pharmacotherapyCharles F Reynolds
Department of Psychiatry, University of Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 68:51-60. 2011..Cognitive impairment in late-life depression is a core feature of the illness...
Somatic symptoms of depression in elderly patients with medical comorbiditiesRebecca A Drayer
Center for Research on Health Care, Division of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Int J Geriatr Psychiatry 20:973-82. 2005..Rating scales emphasizing somatic symptoms associated with depression may provide a more accurate measure of depression severity than those excluding such symptoms...
Impact of chronic musculoskeletal pathology on older adults: a study of differences between knee OA and low back painNatalia E Morone
Department of Medicine, Division of General Internal Medicine, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Pain Med 10:693-701. 2009....
Factors associated with pain interference in an epidemiologic sample of adults with bipolar I disorderBenjamin I Goldstein
Advanced Center for Intervention and Services Research for Late Life Mood Disorders, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States
J Affect Disord 117:151-6. 2009..Epidemiologic studies have found that major depressive disorder (MDD) and anxiety disorders are associated with pain. However, little is known regarding the prevalence and correlates of pain in bipolar I disorder (BD)...
A review of the effectiveness of antidepressant medications for depressed nursing home residentsRichard D Boyce
Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA
J Am Med Dir Assoc 13:326-31. 2012..Despite a significant increase in the rate of antidepressant prescribing over the past several decades, little is known about the effectiveness of these agents in the NH population...
A comparison of the frequencies of risk factors for depression in older black and white participants in a study of indicated preventionRoy Sriwattanakomen
University of Pittsburgh School of Medicine, Graduate School of Public Health, Pittsburgh, PA, USA
Int Psychogeriatr 22:1240-7. 2010..To compare the frequencies of risk factors, we describe risks for depression as a function of race among consecutively admitted participants in a randomized clinical trial of indicated depression prevention in later life...
Treatment of late-life depression alleviates caregiver burdenLynn M Martire
Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA
J Am Geriatr Soc 58:23-9. 2010..To describe the burden experienced by family caregivers of older adults with depression and to examine the positive effects on caregivers of treating late-life depression...
Getting better, getting well: understanding and managing partial and non-response to pharmacological treatment of non-psychotic major depression in old ageHenry C Driscoll
Advanced Center for Interventions and Services Research for Late Life Mood Disorders, and the John A Hartford Center for Excellence in Geriatric Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Drugs Aging 24:801-14. 2007..Subsequently, maintenance treatment with the same regimen that has been successful in relieving the depression strongly improves the patient's chances of remaining depression free...
Older people's experiences of patient-centered treatment for chronic pain: a qualitative studyCarrie F Teh
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Pain Med 10:521-30. 2009..Older adults with chronic pain who seek treatment often are in a health care environment that emphasizes patient-directed care, a change from the patriarchal model of care to which many older adults are accustomed...
Achieving long-term optimal outcomes in geriatric depression and anxietyBenoit H Mulsant
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
CNS Spectr 8:27-34. 2003....
Age-related changes in antidepressant pharmacokinetics and potential drug-drug interactions: a comparison of evidence-based literature and package insert informationRichard D Boyce
Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Geriatr Pharmacother 10:139-50. 2012..Little is known about the best source of pharmacotherapy information to consult about key factors necessary to safely prescribe these medications to older patients...
Venlafaxine XR and chronic pelvic pain syndromeJordan F Karp
J Clin Psychiatry 65:880-1. 2004
Pain in persons with dementia: complex, common, and challengingJoseph Shega
Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
J Pain 8:373-8. 2007
Research Grants
- Optimizing Care for Older Adults with Back Pain and DepressionJordan F Karp; Fiscal Year: 2010....
