Research Topics
| B KarolewiczSummaryAffiliation: University of Mississippi Medical Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Nitric oxide synthase inhibitors have antidepressant-like properties in mice. 2. Chronic treatment results in downregulation of cortical beta-adrenoceptorsB Karolewicz
Department of Psychiatry, University of Mississippi Medical Center, Jackson 39216 4505, USA
Eur J Pharmacol 372:215-20. 1999....
Elevated levels of NR2A and PSD-95 in the lateral amygdala in depressionBeata Karolewicz
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
Int J Neuropsychopharmacol 12:143-53. 2009..Amounts of NR1, nNOS, glutamine synthetase, and GAD-67 were unchanged. Increased levels of NR2A and PSD-95 suggest that glutamate signalling at the NMDA receptor in the amygdala is disrupted in depression...
Reduced level of glutamic acid decarboxylase-67 kDa in the prefrontal cortex in major depressionBeata Karolewicz
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS 39216, USA
Int J Neuropsychopharmacol 13:411-20. 2010..Moreover, our data support previous neuroimaging observations that antidepressant medication normalizes GABA deficits in depression...
Low nNOS protein in the locus coeruleus in major depressionB Karolewicz
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
J Neurochem 91:1057-66. 2004..However, pH appears to effect preservation of nNOS immunoreactivity in subjects with depression. This factor may contribute, in part, to low levels of nNOS in depression...
Rapid eye movement sleep deprivation decreases long-term potentiation stability and affects some glutamatergic signaling proteins during hippocampal developmentJ Lopez
Department of Psychiatry, University of Mississippi School of Medicine, 2500 N State Street, Jackson, MS 39216, USA
Neuroscience 153:44-53. 2008..The findings support a role for REMS in the maturation of hippocampal neuronal circuits...
Chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampusA H Iyo
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Neuroscience 169:1567-74. 2010..Our findings suggest that elevated levels of glucocorticoids may contribute to impairments in glutamate neurotransmission in MDD...
