Research Topics
| ARUN S contact KARLAMANGLASummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Trajectories of cognitive function in late life in the United States: demographic and socioeconomic predictorsArun S Karlamangla
UCLA Division of Geriatrics, Los Angeles, CA 90095, USA
Am J Epidemiol 170:331-42. 2009....
Reduction in allostatic load in older adults is associated with lower all-cause mortality risk: MacArthur studies of successful agingArun S Karlamangla
Division of Geriatrics, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Psychosom Med 68:500-7. 2006..To study the association between change in allostatic load (a risk score constructed from multiple biological markers) over a 2.5-year period and mortality in the following 4.5 years in older adults...- Comorbidity in older adults: nosology of impairment, diseases, and conditionsArun Karlamangla
UCLA Division of Geriatrics, David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, CA 90095, USA
J Gerontol A Biol Sci Med Sci 62:296-300. 2007..As the knowledge base grows, the nosology can be updated to add new domains and refine extant ones... - Longitudinal trajectories of heavy drinking in adults in the United States of AmericaArun Karlamangla
Dvision of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1687, USA
Addiction 101:91-9. 2006..To estimate age, period, cohort and other demographic influences on heavy alcohol consumption and trajectories of heavy drinking in American adults... - Urinary cortisol excretion as a predictor of incident cognitive impairmentArun S Karlamangla
Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte 2339, Los Angeles, CA 90095 1687, USA
Neurobiol Aging 26:80-4. 2005..07-5.14). There was no effect modification by gender; the association was equally strong in men and women. We conclude that urinary excretion of cortisol predicts incident cognitive impairment in older men and women... - Increase in epinephrine excretion is associated with cognitive decline in elderly men: MacArthur studies of successful agingArun S Karlamangla
Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte 2339, Los Angeles, CA 90095 1687, USA
Psychoneuroendocrinology 30:453-60. 2005..Our objective was to investigate whether increase over time in urinary epinephrine excretion in older adults was associated with subsequent cognitive decline... - Impact of socioeconomic status on longitudinal accumulation of cardiovascular risk in young adults: the CARDIA Study (USA)Arun S Karlamangla
Division of Geriatrics, UCLA School of Medicine, 10945 Le Conte 2339, Los Angeles, CA 90095 1687, USA
Soc Sci Med 60:999-1015. 2005.... - Socioeconomic and ethnic disparities in cardiovascular risk in the United States, 2001-2006Arun S Karlamangla
Division of Geriatrics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
Ann Epidemiol 20:617-28. 2010..To quantify socioeconomic status and ethnic differences in risk for coronary heart disease (CHD) accrued from major risk factors in the United States... - Light to moderate alcohol consumption and disability: variable benefits by health statusArun S Karlamangla
Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA
Am J Epidemiol 169:96-104. 2009..Alcohol consumption in moderation might reduce the risk of developing physical disability in older adults in good health but not in those in poor health... - Increased mortality risk in older adults with persistently low or declining feelings of usefulness to othersTara L Gruenewald
University of California, Los Angeles, USA
J Aging Health 21:398-425. 2009..This study seeks to determine if persistently low or declining feelings of usefulness to others in later life predict increased mortality hazard in older adults... - Combinations of biomarkers predictive of later life mortalityTara L Gruenewald
Department of Medicine/Geriatrics, University of California, Los Angeles, CA 90095-1687, USA
Proc Natl Acad Sci U S A 103:14158-63. 2006.... - Hyperkyphosis predicts mortality independent of vertebral osteoporosis in older womenDeborah M Kado
University of California, Los Angeles, Los Angeles, California, USA
Ann Intern Med 150:681-7. 2009..Excessive kyphosis may be associated with earlier mortality, but previous studies have not controlled for clinically silent vertebral fractures, which are a known mortality risk factor... - Urban neighborhood context and change in depressive symptoms in late lifeRichard G Wight
Department of Community Health Sciences, School of Public Health, Box 951772, 650 Young Drive South, University of California, Los Angeles, Los Angeles, CA 90095 1772, USA
J Gerontol B Psychol Sci Soc Sci 64:247-51. 2009..This study examines associations between urban neighborhood sociodemographic characteristics and change over time in late-life depressive symptoms... - Waist-hip-ratio as a predictor of all-cause mortality in high-functioning older adultsPreethi Srikanthan
David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Ann Epidemiol 19:724-31. 2009..We assessed the relationship between three measures of obesity and all-cause mortality in a group of healthy older adults... 
Yoga decreases kyphosis in senior women and men with adult-onset hyperkyphosis: results of a randomized controlled trialGail A Greendale
Division of Geriatrics, Geffen School of Medicine, University of California at Los Angeles, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095, USA
J Am Geriatr Soc 57:1569-79. 2009..To assess whether a specifically designed yoga intervention can reduce hyperkyphosis...- Allostatic load and frailty in older adultsTara L Gruenewald
Department of Medicine, Division of Geriatrics, Geffen School of Medicine, University of California at Los Angeles, 10945 LeConte Ave, Suite 2339, Los Angeles, CA 90095, USA
J Am Geriatr Soc 57:1525-31. 2009..To examine the association between allostatic load (AL), an index of multisystem physiological dysregulation, and frailty development over a 3-year follow-up in a sample of older adults... - Disability trends among older Americans: National Health And Nutrition Examination Surveys, 1988-1994 and 1999-2004Teresa E Seeman
Division of Geriatrics, David Geffen School of Medicine, University of California, Los Angeles, 10945 Le Conte Ave, Los Angeles, CA 90095, USA
Am J Public Health 100:100-7. 2010..We investigated trends in disability among older Americans from 1988 through 2004 to test the hypothesis that more recent cohorts show increased burdens of disability... - Urban neighborhood context and mortality in late lifeRichard G Wight
University of California, Los Angeles, CA 90095, USA
J Aging Health 22:197-218. 2010..To examine the contextual effects of urban neighborhood characteristics on mortality among older adults... - Early environment affects neuroendocrine regulation in adulthoodShelley E Taylor
Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Los Angeles, CA 90095 1563, USA
Soc Cogn Affect Neurosci 6:244-51. 2011..Participants in the bottom tertile showed more signs of HPA axis dysregulation than those in the top tertile. We discuss processes that may underlie these effects, with reference to the theory of allostatic load... - Menopause-associated symptoms and cognitive performance: results from the study of women's health across the nationGail A Greendale
University of California, Los Angeles, USA
Am J Epidemiol 171:1214-24. 2010..The authors found that depressive, anxiety, sleep disturbance, and vasomotor symptoms did not account for the transient decrement in SDMT learning observed during late perimenopause... - Allostatic load as a predictor of functional decline. MacArthur studies of successful agingArun S Karlamangla
Division of Geriatrics, Department of Medicine, UCLA School of Medicine, USA
J Clin Epidemiol 55:696-710. 2002..We conclude that a summary measure of physiologic dysregulation, such as allostatic load, is an independent predictor of functional decline in elderly men and women... - Serum albumin concentration and waiting list mortality in idiopathic interstitial pneumoniaDavid A Zisman
Interstitial Lung Disease Center, David Geffen School of Medicine at UCLA, 37 131 Center for Health Sciences, Los Angeles, CA 90095, USA
Chest 135:929-35. 2009..The objective of this study was to examine the relationship between serum albumin concentration and mortality in a large cohort of patients with idiopathic interstitial pneumonia listed for lung transplantation... - Validation of a method to screen for pulmonary hypertension in advanced idiopathic pulmonary fibrosisDavid A Zisman
Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
Chest 133:640-5. 2008..The objective of this study was to validate this method in a separate group of IPF patients... - Hip fracture risk assessment using composite indices of femoral neck strength: the Rancho Bernardo studyArun S Karlamangla
Division of Geriatrics, UCLA School of Medicine, 10945 Le Conte Avenue, Suite 2339, Box 951687, Los Angeles, CA 90095-1687, USA
Osteoporos Int 15:62-70. 2004..This needs further exploration in larger cohorts and in different population sub-groups... - Increases in serum non-high-density lipoprotein cholesterol may be beneficial in some high-functioning older adults: MacArthur studies of successful agingArun S Karlamangla
Division of Geriatrics, Department of Medicine, School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA
J Am Geriatr Soc 52:487-94. 2004..objectives: To examine the association between changes in serum non-high-density lipoprotein cholesterol (non-HDL-C) over a 2.5-year period and risk of adverse health outcomes in the following 4.5 years in high-functioning older adults... - Hyperkyphotic posture predicts mortality in older community-dwelling men and women: a prospective studyDeborah M Kado
Division of Geriatrics, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, California 90095, USA
J Am Geriatr Soc 52:1662-7. 2004..To determine the association between hyperkyphotic posture and rate of mortality and cause-specific mortality in older persons... - Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful AgingDeborah M Kado
Division of Geriatrics, Department of Medicine, The David Geffen School of Medicine at University of California Los Angeles, 90095, USA
Am J Med 118:161-7. 2005..Further, high homocysteine levels are associated with low vitamin status, and it is unknown whether it is homocysteine toxicity or vitamin insufficiency that is responsible for the observed cognitive dysfunction... - Urban neighborhood context, educational attainment, and cognitive function among older adultsRichard G Wight
Department of Community Health Sciences, School of Public Health, University of California, Los Angeles, CA 90095, USA
Am J Epidemiol 163:1071-8. 2006.... - Feelings of Usefulness to Others, Disability, and Mortality in Older Adults: the MacArthur Study of Successful AgingTara L Gruenewald
Department of Medicine Geriatrics, UCLA Geffen School of Medicine, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
J Gerontol B Psychol Sci Soc Sci 62:P28-37. 2007..This suggests that feelings of usefulness may shape health trajectories in older adults... - Urban neighborhoods and depressive symptoms among older adultsCarol S Aneshensel
Department of Community Health Sciences, School of Public Health, University of California, Los Angeles, Box 951772, 650 Young Drive South, Los Angeles, CA 90095 1772, USA
J Gerontol B Psychol Sci Soc Sci 62:S52-9. 2007.... - Depressive symptoms as a predictor of cognitive decline: MacArthur Studies of Successful AgingJoshua Chodosh
VA Greater Los Angeles Health System, HSR and D COE and GRECC, Los Angeles, CA 90073, USA
Am J Geriatr Psychiatry 15:406-15. 2007..Our objective was to examine the association between depressive symptoms and longitudinal cognitive changes in older adults who were high-functioning at baseline... - High-resolution chest CT findings do not predict the presence of pulmonary hypertension in advanced idiopathic pulmonary fibrosisDavid A Zisman
Department of Medicine, David Geffen School of Medicine at UCLA, 37 131 Center for Health Sciences, Los Angeles, CA 90095, USA
Chest 132:773-9. 2007..We tested the hypothesis that chest CT-determined extent of pulmonary fibrosis and/or main pulmonary artery diameter (MPAD) can be used to identify the presence of PH in patients with advanced IPF... - Prediction of pulmonary hypertension in idiopathic pulmonary fibrosisDavid A Zisman
Department of Medicine, Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
Respir Med 101:2153-9. 2007..We tested the hypothesis that the forced vital capacity to diffusing capacity ratio and room air resting pulse oximetry may be combined to predict mean pulmonary artery pressure (MPAP) in idiopathic pulmonary fibrosis... - A multilevel analysis of urban neighborhood socioeconomic disadvantage and health in late lifeRichard G Wight
Department of Community Health Sciences, UCLA School of Public Health, Los Angeles, CA 90095, USA
Soc Sci Med 66:862-72. 2008..In late life, neighborhood socioeconomic disadvantage is more consequential to subjective appraisals of health than diagnosed CVD or functional limitations... - Depressive symptoms, chronic diseases, and physical disabilities as predictors of cognitive functioning trajectories in older AmericansJoshua Chodosh
Geriatric Research, Education, and Clinical Center, Health Services Research and Development Center of Excellence, Veterans Affairs Greater Los Angeles Health System, Los Angeles, California 90073, USA
J Am Geriatr Soc 58:2350-7. 2010..To determine the concurrent influence of depressive symptoms, medical conditions, and disabilities in activities of daily living (ADLs) on rates of decline in cognitive function of older Americans... - Moderate alcohol consumption and safety of lovastatin and warfarin among men: the post-coronary artery bypass graft trialKenneth J Mukamal
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
Am J Med 119:434-40. 2006..Although moderate drinking has been associated with lower mortality among patients with coronary heart disease, its safety among patients taking common cardiac medications is unknown...
Research Grants
- A Risk Score for Cardiovascular Disease in Older AdultsArun Karlamangla; Fiscal Year: 2007..The proposed research will lead to better risk assessment and to improved targeting of preventive interventions in these older adults. ..
- Lifespan Psychosocial Profiles and Biological Pathways to Bone StrengthARUN S contact KARLAMANGLA; Fiscal Year: 2010....