Roksana Karim

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Association of HIV clinical disease progression with profiles of early immune activation: results from a cluster analysis approach
    Roksana Karim
    Department of Pediatrics, Maternal, Child and Adolescent Center for Infectious Diseases and Virology, University of Southern California, Los Angeles, California, USA
    AIDS 27:1473-81. 2013
  2. pmc Gonadotropin and sex steroid levels in HIV-infected premenopausal women and their association with subclinical atherosclerosis in HIV-infected and -uninfected women in the women's interagency HIV study (WIHS)
    Roksana Karim
    Departments of Pediatrics, University of Southern California, Los Angeles, CA 90033, USA
    J Clin Endocrinol Metab 98:E610-8. 2013
  3. pmc Relationship between serum levels of sex hormones and progression of subclinical atherosclerosis in postmenopausal women
    Roksana Karim
    Department of Pediatrics, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP Suite 222R, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 93:131-8. 2008
  4. pmc Influence of age and obesity on serum estradiol, estrone, and sex hormone binding globulin concentrations following oral estrogen administration in postmenopausal women
    Roksana Karim
    Department of Pediatrics, University of Southern California, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 94:4136-43. 2009
  5. pmc Relation of Framingham risk score to subclinical atherosclerosis evaluated across three arterial sites
    Roksana Karim
    Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Am J Cardiol 102:825-30. 2008
  6. pmc Associations between markers of inflammation and physiological and pharmacological levels of circulating sex hormones in postmenopausal women
    Roksana Karim
    Department of Pediatrics and Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Menopause 17:785-90. 2010
  7. pmc Hip fracture in postmenopausal women after cessation of hormone therapy: results from a prospective study in a large health management organization
    Roksana Karim
    Department of Pediatrics and Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Menopause 18:1172-7. 2011
  8. ncbi request reprint The association of smoking and subclinical atherosclerosis in Type 2 diabetes: modification by duration of diabetes
    R Karim
    Department of Preventive Medicine, Keck School of Medicine, University of South Carlifornia, Los Angeles, CA, USA
    Diabet Med 22:81-7. 2005
  9. ncbi request reprint Determinants of the effect of estrogen on the progression of subclinical atherosclerosis: Estrogen in the Prevention of Atherosclerosis Trial
    Roksana Karim
    Department of Preventive Medicine, Keck School of Medicine, Los Angeles, California, USA
    Menopause 12:366-73. 2005
  10. pmc Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus
    Andrea Kovacs
    Maternal, Child, and Adolescent, Center for Infectious Diseases and Virology, University of Southern California, Keck School of Medicine, HRA 300, 1640 Marengo St, Los Angeles, CA 90033, USA
    J Infect Dis 201:823-34. 2010

Detail Information

Publications25

  1. pmc Association of HIV clinical disease progression with profiles of early immune activation: results from a cluster analysis approach
    Roksana Karim
    Department of Pediatrics, Maternal, Child and Adolescent Center for Infectious Diseases and Virology, University of Southern California, Los Angeles, California, USA
    AIDS 27:1473-81. 2013
    ..CD4 and CD8 T-cell activation are independent predictors of AIDS. The complete activation profile of both T-cell subtypes and their predictive value for AIDS risk is largely unknown...
  2. pmc Gonadotropin and sex steroid levels in HIV-infected premenopausal women and their association with subclinical atherosclerosis in HIV-infected and -uninfected women in the women's interagency HIV study (WIHS)
    Roksana Karim
    Departments of Pediatrics, University of Southern California, Los Angeles, CA 90033, USA
    J Clin Endocrinol Metab 98:E610-8. 2013
    ..We investigated the association of sex hormone and gonadotropin concentrations with subclinical atherosclerosis in HIV-infected and -uninfected premenopausal women in the Women's Interagency HIV Study...
  3. pmc Relationship between serum levels of sex hormones and progression of subclinical atherosclerosis in postmenopausal women
    Roksana Karim
    Department of Pediatrics, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP Suite 222R, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 93:131-8. 2008
    ..Postmenopausal hormone therapy has been examined extensively in relation to cardiovascular disease. However, research relating serum levels of sex hormones to cardiovascular disease is sparse, and the results are inconclusive...
  4. pmc Influence of age and obesity on serum estradiol, estrone, and sex hormone binding globulin concentrations following oral estrogen administration in postmenopausal women
    Roksana Karim
    Department of Pediatrics, University of Southern California, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 94:4136-43. 2009
    ..Risk of venous thrombosis and stroke is higher in older, overweight, and obese women using HT. However, the impact of age and obesity on estrogen concentrations among HT users is not well defined...
  5. pmc Relation of Framingham risk score to subclinical atherosclerosis evaluated across three arterial sites
    Roksana Karim
    Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Am J Cardiol 102:825-30. 2008
    ..Evaluation of subclinical atherosclerosis in different arterial sites in addition to FRS may be useful in targeting subjects for lifestyle and other interventions...
  6. pmc Associations between markers of inflammation and physiological and pharmacological levels of circulating sex hormones in postmenopausal women
    Roksana Karim
    Department of Pediatrics and Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Menopause 17:785-90. 2010
    ..It is not known how sex hormone concentrations relate to the markers of inflammation in postmenopausal women taking or not taking hormone therapy...
  7. pmc Hip fracture in postmenopausal women after cessation of hormone therapy: results from a prospective study in a large health management organization
    Roksana Karim
    Department of Pediatrics and Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Menopause 18:1172-7. 2011
    ..We evaluated the impact of HT cessation on hip fracture incidence in a large cohort from the Southern California Kaiser Permanente health management organization...
  8. ncbi request reprint The association of smoking and subclinical atherosclerosis in Type 2 diabetes: modification by duration of diabetes
    R Karim
    Department of Preventive Medicine, Keck School of Medicine, University of South Carlifornia, Los Angeles, CA, USA
    Diabet Med 22:81-7. 2005
    ..The primary objective of this paper was to evaluate the impact of smoking on atherosclerosis among Type 2 diabetic patients and to evaluate whether smoking associations with atherosclerosis are modified by diabetes-related variables...
  9. ncbi request reprint Determinants of the effect of estrogen on the progression of subclinical atherosclerosis: Estrogen in the Prevention of Atherosclerosis Trial
    Roksana Karim
    Department of Preventive Medicine, Keck School of Medicine, Los Angeles, California, USA
    Menopause 12:366-73. 2005
    ....
  10. pmc Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus
    Andrea Kovacs
    Maternal, Child, and Adolescent, Center for Infectious Diseases and Virology, University of Southern California, Keck School of Medicine, HRA 300, 1640 Marengo St, Los Angeles, CA 90033, USA
    J Infect Dis 201:823-34. 2010
    ....
  11. ncbi request reprint Correlates of prevalent hypertension in a large cohort of HIV-infected women: Women's Interagency HIV Study
    Ann Khalsa
    University of Southern California, Los Angeles, California, USA
    AIDS 21:2539-41. 2007
    ..0001), and body mass index greater than 30 kg/m (P < 0.0001), whereas current pregnancy was protective (P < 0.04). HIV infection, CD4 cell count, HIV-1 viral load, and antiretroviral therapy were not associated with hypertension...
  12. ncbi request reprint Prognostic factors in HIV-related diffuse large-cell lymphoma: before versus after highly active antiretroviral therapy
    Soon Thye Lim
    Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Clin Oncol 23:8477-82. 2005
    ....
  13. ncbi request reprint Correlates of CD4+ and CD8+ lymphocyte counts in high-risk immunodeficiency virus (HIV)-seronegative women enrolled in the women's interagency HIV study (WIHS)
    Marek J Nowicki
    Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Hum Immunol 68:342-9. 2007
    ..Multiple demographic and behavioral factors may influence CD4 and CD8 counts in HIV negative women. These factors must be considered in future analyses comparing lymphocyte subsets in HIV positive and negative women...
  14. pmc Correlates of perinatal depression in HIV-infected women
    Suad Kapetanovic
    USC Keck School of Medicine, Department of Psychiatry and Behavioral Sciences, HRA Building, Suite 300, Los Angeles, CA 90033, USA
    AIDS Patient Care STDS 23:101-8. 2009
    ..We conclude that pregnant HIV-infected women should be routinely screened for PND. Prospective studies examining the bio-psycho-social markers of PND in HIV-infected women are indicated...
  15. pmc Permissive and protective factors associated with presence, level, and longitudinal pattern of cervicovaginal HIV shedding
    James Homans
    Maternal, Child and Adolescent Center for Infectious Diseases and Virology, Department of Pediatrics, Division of Infectious Disease, University of Southern California Keck School of Medicine, Los Angeles, CA USA
    J Acquir Immune Defic Syndr 60:99-110. 2012
    ..Plasma viral load (PVL) correlates with CV-VL, but discordance is frequent. We evaluated how PVL, behavioral, immunological, and local factors/conditions individually and collectively correlate with CV-VL...
  16. pmc Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection
    Iftach Shaked
    From the Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA I S, K L Department of Epidemiology and Population Health, Department of Medicine D B H, D T, K A, R K, and Department of Obstetrics and Gynecology and Women s Health K A, and Department of Microbiology and Immunology V P, Albert Einstein College of Medicine, Bronx, NY Department of Immunology Microbiology, Rush University, Chicago, IL J P, M C, A L L Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD E T G Division of Infectious Disease, Georgetown University Medical Center, Washington, DC M A Y Department of Cardiovascular Disease, SUNY Downstate Medical Center, Brooklyn, NY J L Atherosclerosis Research Unit, University of Southern California, Los Angeles, CA R K Department of Medicine, University of California, San Francisco P C T Department of Cardiology, Angiology and Pneumonology, University of Heidelberg, Germany C G and Department of Medicine, University of California, San Diego B M
    Arterioscler Thromb Vasc Biol 34:1085-92. 2014
    ..Our goal was to identify plasma biomarkers that reflect macrophage inflammation and are associated with subclinical atherosclerosis...
  17. pmc Effect of HAART on salivary gland function in the Women's Interagency HIV Study (WIHS)
    M Navazesh
    USC School of Dentistry, Los Angeles, CA 90089 0641, USA
    Oral Dis 15:52-60. 2009
    ..To determine the impact of highly active antiretroviral therapy (HAART) on salivary gland function in human immunodeficiency virus (HIV) positive women from the Women's Interagency HIV Study (WIHS)...
  18. ncbi request reprint Neutropenia in human immunodeficiency virus infection: data from the women's interagency HIV study
    Alexandra M Levine
    Department of Medicine, Division of Hematology, University of Southern California, Los Angeles, CA 90033, USA
    Arch Intern Med 166:405-10. 2006
    ..Neither the effect of highly active antiretroviral therapy (HAART) on neutrophil counts nor the significance of neutropenia in terms of survival has previously been evaluated...
  19. ncbi request reprint Antiretroviral therapy modifies the genetic effect of known type 2 diabetes-associated risk variants in HIV-infected women
    Melissa A Frasco
    aDepartment of Preventive Medicine, University of Southern California bDepartment of Physiology and Biophysics University of Southern California cUSC Diabetes and Obesity Research Institute, University of Southern California, Los Angeles, California dMontefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York eStroger Hospital and Rush University, Chicago, Illinois fJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland gState University New York Downstate Medical Center, Brooklyn, New York hGeorgetown University School of Medicine, District of Columbia iUniversity of California San Francisco jDepartment of Veterans Affairs, San Francisco, California, USA Wendy J Mack and Celeste Leigh Pearce contributed equally to the writing of this article
    AIDS 28:1815-23. 2014
    ..We examined the associations of diabetes mellitus with known diabetes mellitus-risk alleles from the general population in the context of HIV infection, and explored effect modification by combination antiretroviral therapy (cART)...
  20. pmc Reproductive factors and subtypes of breast cancer defined by hormone receptor and histology
    G Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    Br J Cancer 93:364-71. 2005
    ..This suggests that parity and lactation act through different mechanisms. This study also suggests that reproductive factors have similar protective effects on breast tumours of lobular and ductal origin...
  21. ncbi request reprint AIDS-related Burkitt's lymphoma versus diffuse large-cell lymphoma in the pre-highly active antiretroviral therapy (HAART) and HAART eras: significant differences in survival with standard chemotherapy
    Soon Thye Lim
    Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    J Clin Oncol 23:4430-8. 2005
    ....
  22. ncbi request reprint Impact of highly active antiretroviral therapy on anemia and relationship between anemia and survival in a large cohort of HIV-infected women: Women's Interagency HIV Study
    Kiros Berhane
    Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9011, USA
    J Acquir Immune Defic Syndr 37:1245-52. 2004
    ..Anemia is common in HIV-infected individuals and may be associated with decreased survival...
  23. ncbi request reprint Outcomes of a mind-body treatment program for chronic back pain with no distinct structural pathology--a case series of patients diagnosed and treated as tension myositis syndrome
    David Schechter
    Seligman Medical Institute, Culver City, California, USA
    Altern Ther Health Med 13:26-35. 2007
    ..We believe that a mind-body approach is more effective and involves much less risk and expense than conventional approaches in appropriately diagnosed cases...
  24. pmc Hepatitis C virus quasispecies in HIV-infected women: role of injecting drug use and highly active antiretroviral therapy (HAART)
    Tomasz Laskus
    St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
    Hepatology 46:359-70. 2007
    ..No affect on HCV quasispecies dynamics was noted in relation to CD4 count or highly active antiretroviral therapy (HAART)...
  25. doi request reprint Longitudinal anthropometric patterns among HIV-infected and HIV-uninfected women
    Jessica E Justman
    Department of Epidemiology, Columbia University, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 47:312-9. 2008
    ..Previous studies suggest that indicators of central adiposity such as waist-to-hip ratio (WHR) and waist circumference may be altered by HIV infection, antiretroviral treatment, or both...