Andrew Karellas

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi request reprint Mammographic pattern analysis: an emerging risk assessment tool
    Andrew Karellas
    Acad Radiol 14:511-2. 2007
  2. ncbi request reprint Point/Counterpoint. Cone beam x-ray CT will be superior to digital x-ray tomosynthesis in imaging the breast and delineating cancer
    Andrew Karellas
    Radiology Department, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Med Phys 35:409-11. 2008
  3. pmc Breast cancer imaging: a perspective for the next decade
    Andrew Karellas
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Med Phys 35:4878-97. 2008
  4. pmc Technical note: Skin thickness measurements using high-resolution flat-panel cone-beam dedicated breast CT
    Linxi Shi
    Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Med Phys 40:031913. 2013
  5. doi request reprint Modeling the performance characteristics of computed radiography (CR) systems
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    IEEE Trans Med Imaging 29:790-806. 2010
  6. pmc A perceptual evaluation of JPEG 2000 image compression for digital mammography: contrast-detail characteristics
    Sankararaman Suryanarayanan
    Department of Radiology, Emory University School of Medicine, 1364 Clifton Rd NE, Atlanta, GA 30322, USA
    J Digit Imaging 17:64-70. 2004
  7. pmc Dedicated breast CT: fibroglandular volume measurements in a diagnostic population
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA
    Med Phys 39:7317-28. 2012
  8. ncbi request reprint Solid-state fluoroscopic imager for high-resolution angiography: physical characteristics of an 8 cm x 8 cm experimental prototype
    Srinivasan Vedantham
    Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Med Phys 31:1462-72. 2004
  9. pmc Radiation dose to organs and tissues from mammography: Monte Carlo and phantom study
    Ioannis Sechopoulos
    Department of Radiology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA
    Radiology 246:434-43. 2008
  10. pmc Semi-automated segmentation and classification of digital breast tomosynthesis reconstructed images
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA Srinivasan Vedantham umassmed edu
    Conf Proc IEEE Eng Med Biol Soc 2011:6188-91. 2011

Research Grants

  1. HIGH RESOLUTION CARDIOVASCULAR FLAT-PANEL X-RAY IMAGER
    Andrew Karellas; Fiscal Year: 2001
  2. DIGITAL MAMMOGRAPHY HIGH RESOLUTION FLAT PANEL IMAGER
    Andrew Karellas; Fiscal Year: 2002
  3. New Technology for Computed Radiography
    Andrew Karellas; Fiscal Year: 2007

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Mammographic pattern analysis: an emerging risk assessment tool
    Andrew Karellas
    Acad Radiol 14:511-2. 2007
  2. ncbi request reprint Point/Counterpoint. Cone beam x-ray CT will be superior to digital x-ray tomosynthesis in imaging the breast and delineating cancer
    Andrew Karellas
    Radiology Department, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Med Phys 35:409-11. 2008
  3. pmc Breast cancer imaging: a perspective for the next decade
    Andrew Karellas
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Med Phys 35:4878-97. 2008
    ..We are also likely to transition from a standardized screening, where all women undergo the same imaging exam (mammography), to selection of a screening modality or modalities based an individual-risk or other classification...
  4. pmc Technical note: Skin thickness measurements using high-resolution flat-panel cone-beam dedicated breast CT
    Linxi Shi
    Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Med Phys 40:031913. 2013
    ..To determine the mean and range of location-averaged breast skin thickness using high-resolution dedicated breast CT for use in Monte Carlo-based estimation of normalized glandular dose coefficients...
  5. doi request reprint Modeling the performance characteristics of computed radiography (CR) systems
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    IEEE Trans Med Imaging 29:790-806. 2010
    ..A model such as that addressed in this work could allow for improved understanding of the effect of storage phosphor physical properties and CR reader parameters on objective image quality metrics for existing and evolving CR systems...
  6. pmc A perceptual evaluation of JPEG 2000 image compression for digital mammography: contrast-detail characteristics
    Sankararaman Suryanarayanan
    Department of Radiology, Emory University School of Medicine, 1364 Clifton Rd NE, Atlanta, GA 30322, USA
    J Digit Imaging 17:64-70. 2004
    ..All other compression combinations exhibited significant degradation in CD characteristics...
  7. pmc Dedicated breast CT: fibroglandular volume measurements in a diagnostic population
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA
    Med Phys 39:7317-28. 2012
    ..This information is important for Monte Carlo-based estimation of normalized glandular dose coefficients and for investigating the dependence of VGF on breast dimensions, race, and pathology...
  8. ncbi request reprint Solid-state fluoroscopic imager for high-resolution angiography: physical characteristics of an 8 cm x 8 cm experimental prototype
    Srinivasan Vedantham
    Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Med Phys 31:1462-72. 2004
    ..Since the CCD is three-side buttable, four such CCD modules can be joined to form a 2 x 2 matrix providing a field of view of 16 cm x 16 cm...
  9. pmc Radiation dose to organs and tissues from mammography: Monte Carlo and phantom study
    Ioannis Sechopoulos
    Department of Radiology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA
    Radiology 246:434-43. 2008
    ..To prospectively determine the radiation dose to the organs of the body during standard bilateral two-view mammography by using Monte Carlo simulations and a phantom...
  10. pmc Semi-automated segmentation and classification of digital breast tomosynthesis reconstructed images
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA Srinivasan Vedantham umassmed edu
    Conf Proc IEEE Eng Med Biol Soc 2011:6188-91. 2011
    ..The method may also be adaptable for estimating tumor volume, breast glandular content, and for extracting lesion features for potential application to computer aided detection and diagnosis...
  11. pmc Dedicated breast CT: geometric design considerations to maximize posterior breast coverage
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655 USA
    Phys Med Biol 58:4099-118. 2013
    ....
  12. pmc Scaling-law for the energy dependence of anatomic power spectrum in dedicated breast CT
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Med Phys 40:011901. 2013
    ..To determine the x-ray photon energy dependence of the anatomic power spectrum of the breast when imaged with dedicated breast computed tomography (CT)...
  13. pmc X-ray phase contrast imaging of the breast: analysis of tissue simulating materials
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Med Phys 40:041906. 2013
    ....
  14. pmc Personalized estimates of radiation dose from dedicated breast CT in a diagnostic population and comparison with diagnostic mammography
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Phys Med Biol 58:7921-36. 2013
    ..Future work will investigate methods to reduce and optimize radiation dose from dedicated breast CT. ..
  15. pmc Dedicated breast CT: radiation dose for circle-plus-line trajectory
    Srinivasan Vedantham
    Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Med Phys 39:1530-41. 2012
    ..Hence, this work investigated the glandular dose characteristics of a circle-plus-line trajectory that fulfills data-sufficiency conditions for image reconstruction in dedicated breast CT...
  16. ncbi request reprint Solid-state fluoroscopic imager for high-resolution angiography: parallel-cascaded linear systems analysis
    Srinivasan Vedantham
    Department of Radiology, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, Georgia 30322, USA
    Med Phys 31:1258-68. 2004
    ..5 microR/frame there was no noticeable degradation of the DQE even at the 78 microm pixel pitch mode suggesting that it is feasible to perform high-resolution angiography hitherto unattainable in clinical practice...
  17. doi request reprint Estimating the effective radiation dose imparted to patients by intraoperative cone-beam computed tomography in thoracolumbar spinal surgery
    Jeffrey Lange
    Department of Orthopedic Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Spine (Phila Pa 1976) 38:E306-12. 2013
    ..Observational...
  18. ncbi request reprint Flat-panel digital mammography system: contrast-detail comparison between screen-film radiographs and hard-copy images
    Sankararaman Suryanarayanan
    Departments of Radiology, University of Massachusetts Medical School, Worcester, Mass, USA
    Radiology 225:801-7. 2002
    ..To compare the contrast-detail (CD) characteristics of screen-film (SF) and postprocessed digital images by using a phantom-based method...
  19. ncbi request reprint Clinical comparison of full-field digital mammography and screen-film mammography for detection of breast cancer
    John M Lewin
    University of Colorado Health Sciences Center, 4200 E 9th Ave, Mail Stop F724, Denver, CO 80262, USA
    AJR Am J Roentgenol 179:671-7. 2002
    ..The purpose of this work is to compare full-field digital mammography and screen-film mammography for the detection of breast cancer in a screening population...
  20. ncbi request reprint Detection of rib fractures in an abused infant using digital radiography: a laboratory study
    Paul K Kleinman
    Department of Radiology, UMass Memorial Health Care, Worcester, MA 01655, USA
    Pediatr Radiol 32:896-901. 2002
    ..To assess the diagnostic performance of digital radiography using charge-coupled device (CCD) technology in the detection of rib fracture in infant abuse...
  21. ncbi request reprint Detection of simulated lesions on data-compressed digital mammograms
    Sankararaman Suryanarayanan
    1 Department of Radiology, Emory University School of Medicine, Winship Cancer Institute, 1701 Uppergate Dr, Bldg C, Suite 5018, Atlanta, GA 30322, USA
    Radiology 236:31-6. 2005
    ..To evaluate retrospectively the effect of a wavelet-based compression method on the detection of simulated masses of various sizes and clustered microcalcifications on data-compressed digital mammograms...
  22. ncbi request reprint High-resolution imager for digital mammography: physical characterization of a prototype sensor
    Sankararaman Suryanarayanan
    Emory University School of Medicine, Department of Radiology and Winship Cancer Institute, Atlanta, GA 30322, USA
    Phys Med Biol 50:3957-69. 2005
    ..For a given spectrum, increasing PMMA filtration produced negligible change in DQE(f). The estimated DQE values at zero frequency were in the range between 0.45 and 0.55 under the conditions investigated in this study...
  23. ncbi request reprint Theoretical analysis of high-resolution digital mammography
    Sankararaman Suryanarayanan
    Emory University School of Medicine, Department of Radiology and Winship Cancer Institute, Atlanta, GA 30322, USA
    Phys Med Biol 51:3041-55. 2006
    ..The results of this study strongly suggest the feasibility of large area scintillator-based digital mammography imagers with pixel sizes below 100 microm...
  24. ncbi request reprint Computation of the glandular radiation dose in digital tomosynthesis of the breast
    Ioannis Sechopoulos
    Emory University School of Medicine, Department of Radiology and Winship Cancer Institute, 1701 Uppergate Drive, Suite 5018, Atlanta, Georgia 30322, USA
    Med Phys 34:221-32. 2007
    ..91 to 1.01. The RGD results were fit to mathematical functions and the resulting equations are provided...
  25. ncbi request reprint Scatter radiation in digital tomosynthesis of the breast
    Ioannis Sechopoulos
    Department of Radiology and Winship Cancer Institute, Emory University School of Medicine, 1701 Uppergate Drive, Suite 5018, Atlanta, Georgia 30322, USA
    Med Phys 34:564-76. 2007
    ..The presence of the breast support plate and the detector cover plate in the simulations introduced important effects on the SPR, which are also relevant to the scatter content in planar mammography...
  26. pmc Monte Carlo and phantom study of the radiation dose to the body from dedicated CT of the breast
    Ioannis Sechopoulos
    Department of Radiology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA
    Radiology 247:98-105. 2008
    ..To prospectively determine the radiation dose absorbed by the organs and tissues of the body during a dedicated breast computed tomography (CT) study by using Monte Carlo methods and a phantom...
  27. pmc Detection of simulated microcalcifications in a phantom with digital mammography: effect of pixel size
    Sankararaman Suryanarayanan
    Winship Cancer Institute and Department of Radiology, Emory University School of Medicine, 1701 Uppergate Dr, Bldg C, Suite 5018, Atlanta, GA 30322, USA
    Radiology 244:130-7. 2007
    ..To evaluate the effect of pixel size on the detection of simulated microcalcifications in a phantom with digital mammography...

Research Grants8

  1. HIGH RESOLUTION CARDIOVASCULAR FLAT-PANEL X-RAY IMAGER
    Andrew Karellas; Fiscal Year: 2001
    ..abstract_text> ..
  2. DIGITAL MAMMOGRAPHY HIGH RESOLUTION FLAT PANEL IMAGER
    Andrew Karellas; Fiscal Year: 2002
    ..The proposed prototype using an array of seamlessly tiled CCDs coupled to a structured CsI:TI scintillator by a non-tapering fiberoptic plate will deliver the highest resolution than any other flat panel mammographic detector. ..
  3. New Technology for Computed Radiography
    Andrew Karellas; Fiscal Year: 2007
    ..The potential impact of this inherently low-cost high resolution CR plate reader in a cassette-like package can be very high as it can be easily adapted to the needs of current clinical practice. ..