Mariusz Karbowski

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Photoactivatable green fluorescent protein-based visualization and quantification of mitochondrial fusion and mitochondrial network complexity in living cells
    Mariusz Karbowski
    Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA Electronic address
    Methods Enzymol 547:57-73. 2014
  2. ncbi request reprint Neurodegeneration as a consequence of failed mitochondrial maintenance
    Mariusz Karbowski
    Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Acta Neuropathol 123:157-71. 2012
  3. pmc Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation
    Mariusz Karbowski
    Center for Biomedical Engineering and Technology and Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Curr Opin Cell Biol 23:476-82. 2011
  4. pmc The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover
    Shan Xu
    Center for Biomedical Engineering and Technology, University of Maryland, Baltimore, MD 21201, USA
    Mol Biol Cell 22:291-300. 2011
  5. ncbi request reprint Role of the ubiquitin conjugation system in the maintenance of mitochondrial homeostasis
    Albert Neutzner
    Surgical Neurology Branch National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA
    Ann N Y Acad Sci 1147:242-53. 2008
  6. pmc IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation
    Giovanni Benard
    Center for Biomedical Engineering and Technology, University of Maryland, Baltimore, MD, USA
    EMBO J 29:1458-71. 2010
  7. ncbi request reprint Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission
    Sunan Li
    Center for Biomedical Engineering and Technology, Department of Biochemistry and Molecular Biology, and Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201 Center for Biomedical Engineering and Technology, Department of Biochemistry and Molecular Biology, and Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201
    J Cell Biol 208:109-23. 2015
  8. pmc Effects of overexpression of huntingtin proteins on mitochondrial integrity
    Hongmin Wang
    Institute for Neurodegenerative Diseases, Medical Biotechnology Center, University of Maryland Biotechnology Institute, Baltimore, MD 21201, USA
    Hum Mol Genet 18:737-52. 2009
  9. ncbi request reprint Mitochondria on guard: role of mitochondrial fusion and fission in the regulation of apoptosis
    Mariusz Karbowski
    University of Maryland Biotechnology Institute, Medical Biotechnology Center, 725 W Lombard St, Baltimore, Maryland 21201, USA
    Adv Exp Med Biol 687:131-42. 2010
  10. pmc Mitochondrial fusion and division: Regulation and role in cell viability
    Giovanni Benard
    University of Maryland Biotechnology Institute, Medical Biotechnology Center, Baltimore, MD, USA
    Semin Cell Dev Biol 20:365-74. 2009

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Photoactivatable green fluorescent protein-based visualization and quantification of mitochondrial fusion and mitochondrial network complexity in living cells
    Mariusz Karbowski
    Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA Electronic address
    Methods Enzymol 547:57-73. 2014
    ..Furthermore, since analyses of mitochondrial fusion using mito-PAGFP-based assays rely on time-lapse imaging, critical parameters of time-lapse microscopy and cell preparation are also discussed. ..
  2. ncbi request reprint Neurodegeneration as a consequence of failed mitochondrial maintenance
    Mariusz Karbowski
    Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Acta Neuropathol 123:157-71. 2012
    ..In this review we will discuss various mitochondria-associated conditions, focusing on the role of protein turnover in mitochondrial maintenance with special emphasis on neurodegenerative disorders...
  3. pmc Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation
    Mariusz Karbowski
    Center for Biomedical Engineering and Technology and Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Curr Opin Cell Biol 23:476-82. 2011
    ..The breadth of OMM ubiquitin/proteasome substrates and the physiological relevance of their turnover are only beginning to be understood...
  4. pmc The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover
    Shan Xu
    Center for Biomedical Engineering and Technology, University of Maryland, Baltimore, MD 21201, USA
    Mol Biol Cell 22:291-300. 2011
    ..Our results establish p97 as a novel and essential component of the OMM-associated protein degradation pathway...
  5. ncbi request reprint Role of the ubiquitin conjugation system in the maintenance of mitochondrial homeostasis
    Albert Neutzner
    Surgical Neurology Branch National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA
    Ann N Y Acad Sci 1147:242-53. 2008
    ....
  6. pmc IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation
    Giovanni Benard
    Center for Biomedical Engineering and Technology, University of Maryland, Baltimore, MD, USA
    EMBO J 29:1458-71. 2010
    ....
  7. ncbi request reprint Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission
    Sunan Li
    Center for Biomedical Engineering and Technology, Department of Biochemistry and Molecular Biology, and Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201 Center for Biomedical Engineering and Technology, Department of Biochemistry and Molecular Biology, and Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201
    J Cell Biol 208:109-23. 2015
    ..These data indicate that the dynamic assembly and disassembly of F-actin on the mitochondria participates in Drp1-mediated mitochondrial fission. ..
  8. pmc Effects of overexpression of huntingtin proteins on mitochondrial integrity
    Hongmin Wang
    Institute for Neurodegenerative Diseases, Medical Biotechnology Center, University of Maryland Biotechnology Institute, Baltimore, MD 21201, USA
    Hum Mol Genet 18:737-52. 2009
    ..Furthermore, our results suggest that it might be possible to reverse polyglutamine-induced cytotoxicity by preventing mitochondrial fragmentation...
  9. ncbi request reprint Mitochondria on guard: role of mitochondrial fusion and fission in the regulation of apoptosis
    Mariusz Karbowski
    University of Maryland Biotechnology Institute, Medical Biotechnology Center, 725 W Lombard St, Baltimore, Maryland 21201, USA
    Adv Exp Med Biol 687:131-42. 2010
    ....
  10. pmc Mitochondrial fusion and division: Regulation and role in cell viability
    Giovanni Benard
    University of Maryland Biotechnology Institute, Medical Biotechnology Center, Baltimore, MD, USA
    Semin Cell Dev Biol 20:365-74. 2009
    ..Furthermore, the most recent findings on the role of mitochondrial fusion and division in the maintenance of cell function are also reviewed here in some detail...