Research Topics
| N M KaplanSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Publications
Primary aldosteronism: evidence against a second epidemicNorman M Kaplan
University of Texas Southwestern Medical School, Dallas, TX, USA
J Hypertens 30:1899-902. 2012....
Clinical trials for hypertension: expectations fulfilled and unfulfilledNorman M Kaplan
Hypertension Division, Department of Internal Medicine, University of Texas, Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
Hypertension 49:257-9. 2007
What can we expect from new guidelines?Norman M Kaplan
Department of Medicine, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 8899, USA
Med Clin North Am 88:141-8, ix. 2004....
The current epidemic of primary aldosteronism: causes and consequencesNorman M Kaplan
University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Room CS8 102, Dallas, TX 75390 8899, USA
J Hypertens 22:863-9. 2004....
Déjà vu for primary aldosteronismNorman M Kaplan
University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
Lancet 371:1890-1. 2008
The two-edged sword: controlling hypertension without destroying the patientNorman M Kaplan
University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-8899, USA
Blood Press 13:212-3. 2004
Systemic hypertension: an overview of the problemNorman M Kaplan
Department of Internal Medicine, Division of Hypertension, The University of Texas Southwestern Medical Center, Dallas, TX 75390 8899, USA
Semin Nephrol 25:191-3. 2005..Attempts at prevention are critical but likely are ineffectual. Therefore, the delivery and acceptance of current medical regimens must be improved...
The place of diuretics in preventing cardiovascular eventsN M Kaplan
The University of Texas Southwestern Medical Center, Dallas, TX 75235 8899, USA
J Hum Hypertens 18:S29-32. 2004..As lower blood pressure goals of therapy have been found to be needed, diuretic enhancement of other agents' efficacy has become even more essential. With such low doses, side effects are minimal in degree and infrequent in appearance...
Hypertension curriculum review: lifestyle modifications for prevention and treatment of hypertensionNorman M Kaplan
University of Texas, Southwestern Medical Center, Department of Medicine, 5323 Harry Hines Boulevard, Dallas, TX 75235-8899, USA
J Clin Hypertens (Greenwich) 6:716-9. 2004
Are more tests needed?Norman M Kaplan
Department of Medicine, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
J Clin Hypertens (Greenwich) 10:232-3. 2008
Resistant hypertensionNorman M Kaplan
Department of Internal Medicine, Division of Hypertension, The University of Texas, Southwestern Medical Center, Dallas, Texas 75390, USA
J Hypertens 23:1441-4. 2005..This paper reviews the major causes of resistant hypertension and provides specific recommendations for the evaluation and management of patients with this threatening condition...
Vascular outcome in type 2 diabetes: an ADVANCE?Norman M Kaplan
Department of Internal Medicine, Hypertension Division, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Lancet 370:804-5. 2007
Is there an unrecognized epidemic of primary aldosteronism? ConNorman M Kaplan
University of Texas Southwestern Medical Center, Department of Internal Medicine, Hypertension Division, Dallas, TX 75390, USA
Hypertension 50:454-8; discussion 454-8. 2007
Controversies in hypertensionNorman M Kaplan
University of Texas Southwestern Medical Center, Dallas, TX, USA
Lancet 367:168-76. 2006..We provide the background for these controversies, followed by some opinions on how to guide practitioners to offer more effective management of hypertension...
A comparison of outcomes with angiotensin-converting enzyme inhibitors and diuretics for hypertension in the elderlyNorman M Kaplan
Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75235, USA
Curr Hypertens Rep 5:362-3. 2003
Nonpharmacologic treatment of hypertension in primary health careNorman M Kaplan
Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75235, USA
Curr Hypertens Rep 5:361-2. 2003
Combination therapy for hypertensionNorman M Kaplan
University of Texas Southwestern Medical School, Dallas, TX 75390, USA
Nat Rev Cardiol 6:270-1. 2009....
Can treating the diastolic blood pressure below a certain value increase cardiovascular risk?Norman M Kaplan
University of Texas Southwestern Medical School, Dallas, TX 75390 8586, USA
Curr Cardiol Rep 13:517-9. 2011..Caution is needed in the more intensive and widespread treatment of hypertensive patients to avoid a J-curve...
Current diagnosis and treatment of primary aldosteronismNorman M Kaplan
University of Texas Southwestern Medical Center at Dallas, TX 75390 8586, USA
Expert Rev Cardiovasc Ther 8:1527-30. 2010..Many of these patients are not hypokalemic and can safely be treated without the need for a costly and usually negative work-up...
The diastolic j curve: alive and threateningNorman M Kaplan
Department of Medicine, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390 8586
Hypertension 58:751-3. 2011....
Suggestions for improving the effectiveness of oral presentationsNorman M Kaplan
Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, 75390-8899, USA
J Investig Med 50:419-20. 2002
Prehypertension: is it relevant for nephrologists?Norman M Kaplan
Department of Internal Medicine, Division of Hypertension, University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas, TX 75390 8586, USA
Clin J Am Soc Nephrol 4:1381-3. 2009..It covers more than 60 million people in the United States and nephrologists will increasingly be involved with them. This review describes its relevance to nephrologists...
Treating prehypertension: a review of the evidenceNorman M Kaplan
University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 25390, USA
Curr Hypertens Rep 10:326-9. 2008..Two trials have attempted to document the value of short-term drug therapy to prevent the progression of BP to overt hypertension, but no outcome studies are currently available...
Primary aldosteronism: A contrarian viewNorman M Kaplan
University of Texas Southwestern Medical School, Dallas, TX 75390, USA
Rev Endocr Metab Disord 12:49-52. 2011..Moreover, even if these uncertainties are overcome, the eventual treatment of most who have PA can be provided without the need for extensive testing and expensive treatment...
[The challenge to treat hypertensive patients with type 2 diabetes]N M Kaplan
, , Dallas, USA
Presse Med 31:S25-6. 2002..THERAPEUTIC STRATEGY: Because of the risk of cardiovascular disease, a treatment designed to lower the blood pressure should also reduce the microalbuminuria. Indapamid SR is an excellent choice...
Hypertension trials: 1990 to 2000N M Kaplan
Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, 75390-8899, USA
Curr Opin Nephrol Hypertens 10:501-5. 2001..There are no concerns about the use of calcium antagonists in diabetic patients...
Management of hypertension in patients with type 2 diabetes mellitus: guidelines based on current evidenceN M Kaplan
University of Texas Southwestern Medical Center, Dallas, Texas, USA
Ann Intern Med 135:1079-83. 2001..Attention should also be directed toward nonpharmacologic and pharmacologic control of hyperglycemia and dyslipidemia...
Hypertension and diabetesN M Kaplan
University of Texas Southwestern Medical School, Dallas, TX 75390-8899, USA
J Hum Hypertens 16:S56-60. 2002..Fortunately, the appropriate use of lifestyle changes and multiple drugs will always slow and often stop the progression of this damage...
Low-dose combination therapy: the rationalization for an ACE inhibitor and a calcium channel blocker in higher risk patientsN M Kaplan
Department of Medicine, The University of Texas Southwestern Medical Center, Dallas 75390-8899, USA
Am J Hypertens 14:8S-11S. 2001..Also, combining agents from different classes results in complementary mechanisms of action that provide other cardiovascular protective benefits...
Treatment of coexisting diabetes and hypertensionN M Kaplan
University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8899, USA
Curr Cardiol Rep 3:498-503. 2001..Despite the costs and difficulties of achieving adequate control of these diseases, such patients can be protected from the debilities of diabetes and hypertension...
The early morning rise in blood pressure is related mainly to ambulationA F Khoury
University of Texas Southwestern Medical Center, Department of Internal Medicine, Dallas 75235-8899
Am J Hypertens 5:339-44. 1992..The early morning rise in blood pressure and pulse is mainly related to arising from bed. Possible ways to reduce the abrupt rise in blood pressure and the increase in cardiovascular events that occur after arising are suggested...
The challenge of managing multiple cardiovascular risk factorsN M Kaplan
University of Texas Southwestern Medical Center, Dallas 75235-8899, USA
Am J Hypertens 10:167S-169S. 1997..As has been noted in the other papers in this supplement, the combination of an ACE inhibitor and a calcium antagonist is particularly attractive, not only to treat hypertension, but also to ameliorate other cardiovascular risk factors...
Management of hypertensive patients with multiple cardiovascular risk factorsN M Kaplan
University of Texas Southwestern Medical Center, Dallas 75390-8899, USA
Am J Hypertens 14:221S-224S. 2001..If active therapy is needed for established hypertension, all modifiable unhealthy lifestyles should be addressed along with appropriate drug therapy...
The 6th joint national committee report (JNC-6): new guidelines for hypertension therapy from the USAN M Kaplan
Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas 75235 8899, USA
Keio J Med 47:99-105. 1998..Recommendations are made for improved adherence to therapy, therapy of resistant hypertension and hypertensive crises...
The editor's roundtable: concurrent hypertension and dyslipidemiaVincent E Friedewald
University of Texas Health Sciences Center at Houston, Houston, TX, USA
Am J Cardiol 99:134-44. 2007
Recent clinical trials: the good, the bad, and the misleadingNorman M Kaplan
Hypertension 52:608-9. 2008
The meaning of ALLHATNorman M Kaplan
J Hypertens 21:233-4. 2003
Primary aldosteronism: an update on screening, diagnosis and treatmentNorman M Kaplan
J Hypertens 26:1708-9; author reply 1709-11. 2008
Treatment of hypertension: remaining issues after the Anglo-Scandinavian Cardiac Outcomes TrialNorman M Kaplan
Hypertension 47:10-3. 2006
The ASCOT trial: a closer lookNorman M Kaplan
J Hypertens 24:211-4. 2006
TROPHY: a trial that may change clinical practiceNorman M Kaplan
Curr Hypertens Rep 8:359-60. 2006
HypochondriasisNorman M Kaplan
N Engl J Med 346:783-4. 2002
Exercise and atherosclerosisNorman M Kaplan
Ann Intern Med 141:890; discussion 890. 2004
Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronismNorman M Kaplan
J Hypertens 24:1899; author reply 1899-900. 2006
Morning surge in blood pressureNorman M Kaplan
Circulation 107:1347. 2003
Trial of Preventing Hypertension (TROPHY): design and 2-year progress reportNorman M Kaplan
Hypertension 44:125-6. 2004
Task Force 5: systemic hypertensionNorman M Kaplan
J Am Coll Cardiol 45:1346-8. 2005
An updated meta-analysis with a few surprisesNorman M Kaplan
Hypertension 46:257-8. 2005
Control of blood pressure: does it matter which agent you use?Marvin Moser
J Clin Hypertens (Greenwich) 9:964-73. 2007..The authors maintained full control of the discussion and the resulting content of this article...
[New European guidelines for the management of arterial hypertension: an American perspective]Norman M Kaplan
Pol Arch Med Wewn 117:281-2. 2007
Treatment of hypertension in the prevention and management of ischemic heart disease: a scientific statement from the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and PreventiClive Rosendorff
Veterans Health Administration, USA
Circulation 115:2761-88. 2007
Acupuncture for hypertension: can 2500 years come to an end?Norman M Kaplan
Hypertension 48:815. 2006
Renin-angiotensin system blockade: therapeutic implications beyond blood pressure controlNorman M Kaplan
J Clin Hypertens (Greenwich) 9:2-3. 2007
