Janice W Kansy

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Identification of pyruvate kinase as an antigen associated with Tourette syndrome
    Janice W Kansy
    Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    J Neuroimmunol 181:165-76. 2006
  2. pmc Cdk5 is essential for adult hippocampal neurogenesis
    Diane C Lagace
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 105:18567-71. 2008
  3. pmc Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology
    Douglas A Meyer
    Departments of Psychiatry and Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 105:18561-6. 2008
  4. ncbi request reprint Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability
    David R Benavides
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Neurosci 27:12967-76. 2007
  5. pmc Identification of tyrosine hydroxylase as a physiological substrate for Cdk5
    Janice W Kansy
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    J Neurochem 91:374-84. 2004

Collaborators

  • Lily Y Moy
  • Peter Olausson
  • Jennifer J Quinn
  • James Leckman
  • A Nishi
  • Ralph J DiLeone
  • James A Bibb
  • David R Benavides
  • Paul Greengard
  • Diane C Lagace
  • Douglas A Meyer
  • Amelia J Eisch
  • Marina Mapelli
  • Christopher W Cowan
  • Li Huei Tsai
  • Yong Kim
  • Kanehiro Hayashi
  • Carly F Hale
  • Stanley A Benkovic
  • Diane B Miller
  • Angus C Nairn
  • James P O'Callaghan
  • Edmond Richer
  • Pietro Antich
  • Ammar H Hawasli
  • Ping Zhong
  • Jane R Taylor
  • Zhen Yan

Detail Information

Publications5

  1. pmc Identification of pyruvate kinase as an antigen associated with Tourette syndrome
    Janice W Kansy
    Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    J Neuroimmunol 181:165-76. 2006
    ..These data suggest that PK can function as an autoimmune target and that this immunoreactivity may be associated with Tourette syndrome, OCD, and associated disorders...
  2. pmc Cdk5 is essential for adult hippocampal neurogenesis
    Diane C Lagace
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 105:18567-71. 2008
    ..Thus, Cdk5 has an essential role in the survival, but not proliferation, of adult-generated hippocampal neurons through both cell-intrinsic and cell-extrinsic mechanisms...
  3. pmc Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology
    Douglas A Meyer
    Departments of Psychiatry and Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 105:18561-6. 2008
    ..Thus, dysregulation of Cdk5 dramatically affects striatal-dependent brain function and may be relevant to non-neurodegenerative disorders involving dopamine neurotransmission...
  4. ncbi request reprint Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability
    David R Benavides
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Neurosci 27:12967-76. 2007
    ..These results suggest that Cdk5 acts as a negative regulator of neuronal excitability in the NAc and that Cdk5 may govern the behavioral effects of cocaine and motivation for reinforcement...
  5. pmc Identification of tyrosine hydroxylase as a physiological substrate for Cdk5
    Janice W Kansy
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    J Neurochem 91:374-84. 2004
    ..These results demonstrate direct and indirect regulation of the phosphorylation state of a Cdk5/ERK1/2 site on TH and suggest a role for these pathways in the neuroadaptive changes associated with chronic cocaine exposure...