M Kamboh

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc The application of network label propagation to rank biomarkers in genome-wide Alzheimer's data
    Matthew E Stokes
    Department of Biomedical Informatics, University of Pittsburgh, 5607 Baum Boulevard, 15206 Pittsburgh, PA, USA
    BMC Genomics 15:282. 2014
  2. pmc Connecting the dots: potential of data integration to identify regulatory SNPs in late-onset Alzheimer's disease GWAS findings
    Samantha L Rosenthal
    Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 9:e95152. 2014
  3. pmc A multiethnic replication study of plasma lipoprotein levels-associated SNPs identified in recent GWAS
    Emily K Bryant
    Human Genetics, GSPH, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    PLoS ONE 8:e63469. 2013
  4. pmc Genome-wide association study of antiphospholipid antibodies
    M Ilyas Kamboh
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Autoimmune Dis 2013:761046. 2013
  5. pmc Genome-wide association study of Alzheimer's disease
    M I Kamboh
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Transl Psychiatry 2:e117. 2012
  6. pmc Genetic association between APOE*4 and neuropsychiatric symptoms in patients with probable Alzheimer's disease is dependent on the psychosis phenotype
    Drew Christie
    VISN 20 Mental Illness, Seattle, WA, USA
    Behav Brain Funct 8:62. 2012
  7. pmc Genome-wide association analysis of age-at-onset in Alzheimer's disease
    M I Kamboh
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Mol Psychiatry 17:1340-6. 2012
  8. pmc Association of CLU and PICALM variants with Alzheimer's disease
    M Ilyas Kamboh
    Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA 15261, United States
    Neurobiol Aging 33:518-21. 2012
  9. pmc Association analysis of PON2 genetic variants with serum paraoxonase activity and systemic lupus erythematosus
    Sudeshna Dasgupta
    Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Med Genet 12:7. 2011
  10. pmc Functional polymorphisms of the coagulation factor II gene (F2) and susceptibility to systemic lupus erythematosus
    F Yesim K Demirci
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Rheumatol 38:652-7. 2011

Research Grants

Collaborators

Detail Information

Publications10

  1. pmc The application of network label propagation to rank biomarkers in genome-wide Alzheimer's data
    Matthew E Stokes
    Department of Biomedical Informatics, University of Pittsburgh, 5607 Baum Boulevard, 15206 Pittsburgh, PA, USA
    BMC Genomics 15:282. 2014
    ..This paper evaluates the performance of a multivariate graph-based method called label propagation (LP) that efficiently ranks SNPs in genome-wide data...
  2. pmc Connecting the dots: potential of data integration to identify regulatory SNPs in late-onset Alzheimer's disease GWAS findings
    Samantha L Rosenthal
    Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 9:e95152. 2014
    ..This study further supports the assumption that some of the non-coding GWAS SNPs are true associations rather than tagged associations and demonstrates the application of RegulomeDB to GWAS data. ..
  3. pmc A multiethnic replication study of plasma lipoprotein levels-associated SNPs identified in recent GWAS
    Emily K Bryant
    Human Genetics, GSPH, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    PLoS ONE 8:e63469. 2013
    ..However, the associations were not consistently present in all ethnic groups. This observation was consistent with mixed results obtained in other studies that also examined various ethnic groups...
  4. pmc Genome-wide association study of antiphospholipid antibodies
    M Ilyas Kamboh
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Autoimmune Dis 2013:761046. 2013
    ..Conclusions. We have identified a number of suggestive novel loci for APA that will stimulate follow-up studies in independent and larger samples to replicate our findings...
  5. pmc Genome-wide association study of Alzheimer's disease
    M I Kamboh
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Transl Psychiatry 2:e117. 2012
    ..43. This is a potential candidate gene for AD as this is expressed in the brain and is involved in lipid metabolism. These findings need to be confirmed in additional samples...
  6. pmc Genetic association between APOE*4 and neuropsychiatric symptoms in patients with probable Alzheimer's disease is dependent on the psychosis phenotype
    Drew Christie
    VISN 20 Mental Illness, Seattle, WA, USA
    Behav Brain Funct 8:62. 2012
    ..The E4 allele of the apolipoprotein E (APOE) gene is a well-documented risk factor for the development of AD. However, genetic association studies of the APOE 4 allele and BPS in AD have produced conflicting findings...
  7. pmc Genome-wide association analysis of age-at-onset in Alzheimer's disease
    M I Kamboh
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Mol Psychiatry 17:1340-6. 2012
    ..These findings need to be confirmed in additional well-powered samples...
  8. pmc Association of CLU and PICALM variants with Alzheimer's disease
    M Ilyas Kamboh
    Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA 15261, United States
    Neurobiol Aging 33:518-21. 2012
    ..Our data from an independent and large case-control sample suggest that these gene regions should be followed up by comprehensive resequencing to find functional variants...
  9. pmc Association analysis of PON2 genetic variants with serum paraoxonase activity and systemic lupus erythematosus
    Sudeshna Dasgupta
    Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Med Genet 12:7. 2011
    ....
  10. pmc Functional polymorphisms of the coagulation factor II gene (F2) and susceptibility to systemic lupus erythematosus
    F Yesim K Demirci
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Rheumatol 38:652-7. 2011
    ....

Research Grants6

  1. Functional Characterization-Lipoprotein Lipase Mutations
    M Kamboh; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  2. Analysis of Apolipoprotein H in Lupus
    M Kamboh; Fiscal Year: 2006
    ..Aim 5) perform in vitro mutagenesis and expression studies to express different apoH allelic-isoforms to evaluate isoform-specific inhibition of LDL oxidation. ..
  3. Genetic & Structure-Function Studies: Paraoxonase In SLE
    M Kamboh; Fiscal Year: 2006
    ..We will systematically screen the three PON genes for new mutations (Aim 1) and, in conjunction with known PON potymorphisms, we will evaluate their genetic and functional significances (Aims 2-4). ..
  4. Risk Genes in Alzheimer's Disease
    M Kamboh; Fiscal Year: 2006
    ..S. whites and blacks. The proposed immunochemical, functional, molecular and genetic epidemiological studies will enable us to delineate the role of the apoD in the etiology of AD. ..
  5. Genetic Determinants of HDL-Cholesterol
    M Ilyas Kamboh; Fiscal Year: 2010
    ..As a result of these analyses, we should be able to definitively determine both rare and common variants that contribute to high and low HDL-C levels. ..
  6. Prothrombin Gene Variation and the Risk of SLE and CHD
    M Ilyas Kamboh; Fiscal Year: 2010
    ....