HELEN KALES

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. doi request reprint Racial differences in adherence to antidepressant treatment in later life
    Helen C Kales
    Department of Psychiatry, University of Michigan, Ann Arbor, MI Department of Veterans Affairs, HSR and D Center for Clinical Management Research CCMR, and Serious Mental Illness Treatment, Resource and Evaluation Center SMITREC, Ann Arbor, MI Electronic address
    Am J Geriatr Psychiatry 21:999-1009. 2013
  2. doi request reprint Risk of mortality among individual antipsychotics in patients with dementia
    Helen C Kales
    Ann Arbor VA Center for Clinical Management Research, Serious Mental Illness Treatment, Resource, and Evaluation Center, Ann Arbor, Mich, USA
    Am J Psychiatry 169:71-9. 2012
  3. ncbi request reprint Effect of race and sex on primary care physicians' diagnosis and treatment of late-life depression
    Helen C Kales
    Serious Mental Illness Treatment Research Education and Clinical Center, Health Services Research and Development, Ann Arbor, Michigan, USA
    J Am Geriatr Soc 53:777-84. 2005
  4. ncbi request reprint Race, gender, and psychiatrists' diagnosis and treatment of major depression among elderly patients
    Helen C Kales
    University of Michigan School of Public Health, Ann Arbor, MI 48105, USA
    Psychiatr Serv 56:721-8. 2005
  5. ncbi request reprint Rates of clinical depression diagnosis, functional impairment, and nursing home placement in coexisting dementia and depression
    Helen C Kales
    Psychiatry Service 116A, Ann Arbor VA Medical Center, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Am J Geriatr Psychiatry 13:441-9. 2005
  6. ncbi request reprint International medical graduates and the diagnosis and treatment of late-life depression
    Helen C Kales
    Psychiatry Service 116A, Veterans Affairs Medical Service, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Acad Med 81:171-5. 2006
  7. ncbi request reprint Mortality risk in patients with dementia treated with antipsychotics versus other psychiatric medications
    Helen C Kales
    Serious Mental Illness Treatment Research and Evaluation Center, Health Services Research and Development, VA Ann Arbor Healthcare System, Ann Arbor, Ann Arbor, MI 48109, USA
    Am J Psychiatry 164:1568-76; quiz 1623. 2007
  8. pmc Who receives outpatient monitoring during high-risk depression treatment periods?
    Helen C Kales
    Serious Mental Illness Treatment, Research, and Evaluation Center, Ann Arbor Center of Excellence, Department of Veterans Affairs, Ann Arbor, Michigan, USA
    J Am Geriatr Soc 58:908-13. 2010
  9. doi request reprint Trends in antipsychotic use in dementia 1999-2007
    Helen C Kales
    Veterans Affairs Health Services Researchand Development Center for Clinical Management Research, Serious Mental Illness Treatment, Resource, and Evaluation Center, Ann Arbor, Michigan, USA
    Arch Gen Psychiatry 68:190-7. 2011
  10. ncbi request reprint Cerebrovascular disease and late-life depression
    Helen C Kales
    Section on Geriatric Psychiatry, University of Michigan, Ann Arbor, MI 48105, USA
    Am J Geriatr Psychiatry 13:88-98. 2005

Detail Information

Publications33

  1. doi request reprint Racial differences in adherence to antidepressant treatment in later life
    Helen C Kales
    Department of Psychiatry, University of Michigan, Ann Arbor, MI Department of Veterans Affairs, HSR and D Center for Clinical Management Research CCMR, and Serious Mental Illness Treatment, Resource and Evaluation Center SMITREC, Ann Arbor, MI Electronic address
    Am J Geriatr Psychiatry 21:999-1009. 2013
    ..Although racial differences in depression treatment preferences have been reported, little is known about racial differences in antidepressant medication adherence among older patients...
  2. doi request reprint Risk of mortality among individual antipsychotics in patients with dementia
    Helen C Kales
    Ann Arbor VA Center for Clinical Management Research, Serious Mental Illness Treatment, Resource, and Evaluation Center, Ann Arbor, Mich, USA
    Am J Psychiatry 169:71-9. 2012
    ..The use of antipsychotics to treat the behavioral symptoms of dementia is associated with greater mortality. The authors examined the mortality risk of individual agents to augment the limited information on individual antipsychotic risk...
  3. ncbi request reprint Effect of race and sex on primary care physicians' diagnosis and treatment of late-life depression
    Helen C Kales
    Serious Mental Illness Treatment Research Education and Clinical Center, Health Services Research and Development, Ann Arbor, Michigan, USA
    J Am Geriatr Soc 53:777-84. 2005
    ..To examine primary care physician (PCP) contributions toward racial and sex differences in the diagnosis and treatment of late-life depression...
  4. ncbi request reprint Race, gender, and psychiatrists' diagnosis and treatment of major depression among elderly patients
    Helen C Kales
    University of Michigan School of Public Health, Ann Arbor, MI 48105, USA
    Psychiatr Serv 56:721-8. 2005
    ..This study examined psychiatrists' contributions to racial and gender disparities in diagnosis and treatment among elderly persons...
  5. ncbi request reprint Rates of clinical depression diagnosis, functional impairment, and nursing home placement in coexisting dementia and depression
    Helen C Kales
    Psychiatry Service 116A, Ann Arbor VA Medical Center, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Am J Geriatr Psychiatry 13:441-9. 2005
    ....
  6. ncbi request reprint International medical graduates and the diagnosis and treatment of late-life depression
    Helen C Kales
    Psychiatry Service 116A, Veterans Affairs Medical Service, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Acad Med 81:171-5. 2006
    ..Differences in medical training may affect IMGs' recognition of depression. The authors hypothesized that the diagnosis and treatment of late-life depression would differ between United States medical graduates (USMGs) and IMGs...
  7. ncbi request reprint Mortality risk in patients with dementia treated with antipsychotics versus other psychiatric medications
    Helen C Kales
    Serious Mental Illness Treatment Research and Evaluation Center, Health Services Research and Development, VA Ann Arbor Healthcare System, Ann Arbor, Ann Arbor, MI 48109, USA
    Am J Psychiatry 164:1568-76; quiz 1623. 2007
    ..Mortality rates in the year following new antipsychotic medication starts for neuropsychiatric symptoms of dementia were compared with rates after starts of other psychiatric medications...
  8. pmc Who receives outpatient monitoring during high-risk depression treatment periods?
    Helen C Kales
    Serious Mental Illness Treatment, Research, and Evaluation Center, Ann Arbor Center of Excellence, Department of Veterans Affairs, Ann Arbor, Michigan, USA
    J Am Geriatr Soc 58:908-13. 2010
    ..To examine the intensity of monitoring received by important patient subgroups during high-risk periods (the 12 weeks after psychiatric hospitalization and after new antidepressant starts)...
  9. doi request reprint Trends in antipsychotic use in dementia 1999-2007
    Helen C Kales
    Veterans Affairs Health Services Researchand Development Center for Clinical Management Research, Serious Mental Illness Treatment, Resource, and Evaluation Center, Ann Arbor, Michigan, USA
    Arch Gen Psychiatry 68:190-7. 2011
    ..Concerns about their use began to emerge in 2002, and in 2005, the US Food and Drug Administration warned that use of atypical antipsychotics in dementia was associated with increased mortality...
  10. ncbi request reprint Cerebrovascular disease and late-life depression
    Helen C Kales
    Section on Geriatric Psychiatry, University of Michigan, Ann Arbor, MI 48105, USA
    Am J Geriatr Psychiatry 13:88-98. 2005
    ..Further research is needed to establish the precise linkages and interactions between vascular disease and geriatric depression...
  11. ncbi request reprint Health care utilization by older patients with coexisting dementia and depression
    H C Kales
    Psychiatry Service, Ann Arbor VA Medical Center, MI 48105, USA
    Am J Psychiatry 156:550-6. 1999
    ..The purpose of this study was to compare elderly patients who had coexisting dementia and depression with elderly patients who had either disorder alone in terms of their utilization of inpatient and outpatient services...
  12. ncbi request reprint Combined electroconvulsive therapy and clozapine in treatment-resistant schizophrenia
    H C Kales
    Division of Geriatric Psychiatry, University of Michigan, Ann Arbor, USA
    Prog Neuropsychopharmacol Biol Psychiatry 23:547-56. 1999
    ..The long-term impact of ECT on the course of schizophrenia in patients incompletely responsive to clozapine is not fully elucidated...
  13. ncbi request reprint Race and inpatient psychiatric diagnoses among elderly veterans
    H C Kales
    Psychiatry Service, Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA
    Psychiatr Serv 51:795-800. 2000
    ..The purpose of this study was to examine more closely the issue of race and rates of psychiatric diagnoses among elderly inpatients...
  14. ncbi request reprint Race, psychiatric diagnosis, and mental health care utilization in older patients
    H C Kales
    Geriatric Research, Education, and Clinical Center, Ann Arbor Veterans Affairs Medical Center, Michigan, USA
    Am J Geriatr Psychiatry 8:301-9. 2000
    ..Although inpatient utilization appeared to be similar among races, findings related to outpatient utilization may be associated with such factors as compliance, treatment efficacy, access to health care, or possible clinician bias...
  15. ncbi request reprint Herbal products and other supplements: use by elderly veterans with depression and dementia and their caregivers
    Helen C Kales
    Psychiatry Service 116A, VA Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI, 48105, USA
    J Geriatr Psychiatry Neurol 17:25-31. 2004
    ..In light of the possibility of potentially harmful drug interactions, physicians who treat elderly patients should regularly inquire about the use of these products...
  16. ncbi request reprint Recorded delirium in a national sample of elderly inpatients: potential implications for recognition
    Helen C Kales
    Serious Mental Illness Research and Evaluation Center Health Services Research and Development, Ann Arbor VA Medical Center, Ann Arbor, Michigan 48105, USA
    J Geriatr Psychiatry Neurol 16:32-8. 2003
    ..Future research should prospectively examine recognition of motoric and etiologic delirium subtypes and racial differences in delirium diagnoses...
  17. pmc Antidepressant treatment of veterans with Parkinson's disease and depression: analysis of a national sample
    Peijun Chen
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
    J Geriatr Psychiatry Neurol 20:161-5. 2007
    ..Efforts to improve the care of depressed PD patients should focus instead on improving recognition, ensuring adequacy of treatment, and evaluating the efficacy of existing antidepressants...
  18. pmc Depression in veterans with Parkinson's disease: frequency, co-morbidity, and healthcare utilization
    Peijun Chen
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
    Int J Geriatr Psychiatry 22:543-8. 2007
    ..To determine the frequency of depression in Parkinson's disease (PD) in routine clinical care, and to examine its association with co-morbid psychiatric and medical conditions and healthcare utilization...
  19. ncbi request reprint Disruptive behaviors in Veterans Affairs nursing home residents: how different are residents with serious mental illness?
    John F McCarthy
    Veterans Affairs National Serious Mental Illness Treatment Research and Evaluation Center, Health Services Research and Development, VA Ann Arbor Healthcare System, Ann Arbor, Michigan 48113, USA
    J Am Geriatr Soc 52:2031-8. 2004
    ..To determine the prevalence and correlates of behavior problems of residents of Veterans Affairs (VA) nursing homes and to compare residents with serious mental illness (SMI) with other resident groups...
  20. pmc The effect of depression and cognitive impairment on enrollment in Medicare Part D
    Kara Zivin
    Serious Mental Illness Treatment Research and Evaluation Center, Department of Veterans Affairs, Ann Arbor, Michigan, USA
    J Am Geriatr Soc 57:1433-40. 2009
    ..To examine concerns that vulnerable populations, such as depressed or cognitively impaired beneficiaries would have challenges accessing Part D coverage...
  21. doi request reprint Later-life depression and heart failure
    Susan M Maixner
    Section of Geriatric Psychiatry, Department of Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48109 2700, USA
    Heart Fail Clin 7:47-58. 2011
    ....
  22. ncbi request reprint Diagnosis and management of bipolar disorder with comorbid anxiety in the elderly
    Martha Sajatovic
    Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 67:21-7. 2006
    ..Unfortunately, few evidence-based studies are available to guide the treating clinician in the management of these vulnerable patients, many of whom have additional psychiatric or medical comorbidity...
  23. ncbi request reprint Adherence to depression treatment in older adults: a narrative review
    Kara Zivin
    National VA Serious Mental Illness Treatment, Research and Evaluation Center SMITREC, Ann Arbor, Michigan 48109, USA
    Drugs Aging 25:559-71. 2008
    ....
  24. doi request reprint Increases in Medicare prescription drug plan costs attributable to psychotropic medications
    Kara Zivin
    Department of Veterans Affairs, Health Services Research and Development HSR and D Center of Excellence, Serious Mental Illness Treatment Research and Evaluation Center SMITREC, Ann Arbor, MI, USA
    Am J Geriatr Psychiatry 16:674-85. 2008
    ..Patients' concerns about psychotropic medication costs under Medicare Part D may reinforce these impressions...
  25. ncbi request reprint Benzodiazepine use among depressed patients treated in mental health settings
    Marcia Valenstein
    Department of Veterans Affairs Medical Center, Serious Mental Illness Treatment, Research, and Evaluation Center, and Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
    Am J Psychiatry 161:654-61. 2004
    ..The authors examined benzodiazepine use among a large sample of depressed patients treated in U.S. Department of Veterans Affairs (VA) mental health settings...
  26. doi request reprint Does consideration of Medicare use affect VA evaluations of treatment for new episodes of depression?
    John F McCarthy
    HSR and D Field Program, VA Serious Mental Illness Treatment Research and Evaluation Center, PO Box 130170, Ann Arbor, MI 48113 0170, USA
    Adm Policy Ment Health 35:468-76. 2008
    ..Among the remainder, 3% received Medicare depression treatment and 0.5% were re-classified as having recommended contacts. Medicare use does not substantially supplement VA depression treatment...
  27. ncbi request reprint Complexity in late-life depression: impact of confounding factors on diagnosis, treatment, and outcomes
    Helen C Kales
    Department of Psychiatry, University of Michigan, Ann Arbor Veterans Affairs Medical Center 48105, USA
    J Geriatr Psychiatry Neurol 15:147-55. 2002
    ..Attention to such factors must be included in an agenda for mental health services research, with emphasis on the delivery of effective treatment to elderly patients with depression and improved outcomes in clinical settings...
  28. pmc Enhanced identification of eligibility for depression research using an electronic medical record search engine
    Lisa Seyfried
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Int J Med Inform 78:e13-8. 2009
    ..This was a prospective, observational study to compare the speed and clinical accuracy of a medical record search engine vs. manual review of the EMR...
  29. ncbi request reprint Criminal background checks for psychiatry? Michigan's mental health exceptionalism
    Kara Zivin
    J Am Acad Psychiatry Law 36:6-9. 2008
  30. ncbi request reprint Race and depression: does race affect the diagnosis and treatment of late-life depression?
    Helen C Kales
    VA Ann Arbor Healthcare System and University of Michigan, USA
    Geriatrics 61:18-21. 2006
    ..This article reviews the current literature on racial differences in the diagnosis and treatment of late-life depression, including recent studies on physician contribution to disparities...
  31. ncbi request reprint Age-related modifiers of clinical presentation and health service use among veterans with bipolar disorder
    Martha Sajatovic
    Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    Psychiatr Serv 55:1014-21. 2004
    ....
  32. ncbi request reprint New-onset bipolar disorder in later life
    Martha Sajatovic
    Dept of Psychiatry, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Am J Geriatr Psychiatry 13:282-9. 2005
    ..Selected differences were compared between new-onset and earlier-onset groups...
  33. ncbi request reprint Age comparison of treatment adherence with antipsychotic medications among individuals with bipolar disorder
    Martha Sajatovic
    Psychiatry and Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Int J Geriatr Psychiatry 22:992-8. 2007
    ..We compared adherence with antipsychotic medication among older (age 60 and older) and younger individuals using a large case registry (n = 73,964)...

Research Grants5

  1. 2/2-Personalized Antidepressant Adherence Strategies for Depressed Elders
    Helen C Kales; Fiscal Year: 2010
    ..The purpose of this research is to test a personalized and flexible primary care-based program designed to help patients experience successful depression treatment. ..
  2. Racial Differences in Geriatric Antidepressant Adherence
    HELEN KALES; Fiscal Year: 2007
    ....
  3. Antipsychotics and Mortality in Older Patients
    HELEN KALES; Fiscal Year: 2007
    ..The results of this study will be of immediate relevance to clinicians and policymakers. ..
  4. Antipsychotics and Mortality in Older Patients
    HELEN KALES; Fiscal Year: 2009
    ..The results of this study will be of immediate relevance to clinicians and policymakers. ..