Research Topics
| HELEN KALESSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Risk of mortality among individual antipsychotics in patients with dementiaHelen C Kales
Ann Arbor VA Center for Clinical Management Research, Serious Mental Illness Treatment, Resource, and Evaluation Center, Ann Arbor, Mich, USA
Am J Psychiatry 169:71-9. 2012..The use of antipsychotics to treat the behavioral symptoms of dementia is associated with greater mortality. The authors examined the mortality risk of individual agents to augment the limited information on individual antipsychotic risk...- Trends in antipsychotic use in dementia 1999-2007Helen C Kales
Veterans Affairs Health Services Researchand Development Center for Clinical Management Research, Serious Mental Illness Treatment, Resource, and Evaluation Center, Ann Arbor, Michigan, USA
Arch Gen Psychiatry 68:190-7. 2011..Concerns about their use began to emerge in 2002, and in 2005, the US Food and Drug Administration warned that use of atypical antipsychotics in dementia was associated with increased mortality... - Who receives outpatient monitoring during high-risk depression treatment periods?Helen C Kales
Serious Mental Illness Treatment, Research, and Evaluation Center, Ann Arbor Center of Excellence, Department of Veterans Affairs, Ann Arbor, Michigan, USA
J Am Geriatr Soc 58:908-13. 2010..To examine the intensity of monitoring received by important patient subgroups during high-risk periods (the 12 weeks after psychiatric hospitalization and after new antidepressant starts)... - Mortality risk in patients with dementia treated with antipsychotics versus other psychiatric medicationsHelen C Kales
Serious Mental Illness Treatment Research and Evaluation Center, Health Services Research and Development, VA Ann Arbor Healthcare System, Ann Arbor, Ann Arbor, MI 48109, USA
Am J Psychiatry 164:1568-76; quiz 1623. 2007..Mortality rates in the year following new antipsychotic medication starts for neuropsychiatric symptoms of dementia were compared with rates after starts of other psychiatric medications... - International medical graduates and the diagnosis and treatment of late-life depressionHelen C Kales
Psychiatry Service 116A, Veterans Affairs Medical Service, 2215 Fuller Road, Ann Arbor, MI 48105, USA
Acad Med 81:171-5. 2006..Differences in medical training may affect IMGs' recognition of depression. The authors hypothesized that the diagnosis and treatment of late-life depression would differ between United States medical graduates (USMGs) and IMGs... - Rates of clinical depression diagnosis, functional impairment, and nursing home placement in coexisting dementia and depressionHelen C Kales
Psychiatry Service 116A, Ann Arbor VA Medical Center, 2215 Fuller Road, Ann Arbor, MI 48105, USA
Am J Geriatr Psychiatry 13:441-9. 2005.... - Race, gender, and psychiatrists' diagnosis and treatment of major depression among elderly patientsHelen C Kales
University of Michigan School of Public Health, Ann Arbor, MI 48105, USA
Psychiatr Serv 56:721-8. 2005..This study examined psychiatrists' contributions to racial and gender disparities in diagnosis and treatment among elderly persons... - Effect of race and sex on primary care physicians' diagnosis and treatment of late-life depressionHelen C Kales
Serious Mental Illness Treatment Research Education and Clinical Center, Health Services Research and Development, Ann Arbor, Michigan, USA
J Am Geriatr Soc 53:777-84. 2005..To examine primary care physician (PCP) contributions toward racial and sex differences in the diagnosis and treatment of late-life depression... - Cerebrovascular disease and late-life depressionHelen C Kales
Section on Geriatric Psychiatry, University of Michigan, Ann Arbor, MI 48105, USA
Am J Geriatr Psychiatry 13:88-98. 2005..Further research is needed to establish the precise linkages and interactions between vascular disease and geriatric depression... - Health care utilization by older patients with coexisting dementia and depressionH C Kales
Psychiatry Service, Ann Arbor VA Medical Center, MI 48105, USA
Am J Psychiatry 156:550-6. 1999..The purpose of this study was to compare elderly patients who had coexisting dementia and depression with elderly patients who had either disorder alone in terms of their utilization of inpatient and outpatient services... - Combined electroconvulsive therapy and clozapine in treatment-resistant schizophreniaH C Kales
Division of Geriatric Psychiatry, University of Michigan, Ann Arbor, USA
Prog Neuropsychopharmacol Biol Psychiatry 23:547-56. 1999..The long-term impact of ECT on the course of schizophrenia in patients incompletely responsive to clozapine is not fully elucidated... - Race and inpatient psychiatric diagnoses among elderly veteransH C Kales
Psychiatry Service, Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA
Psychiatr Serv 51:795-800. 2000..The purpose of this study was to examine more closely the issue of race and rates of psychiatric diagnoses among elderly inpatients... - Race, psychiatric diagnosis, and mental health care utilization in older patientsH C Kales
Geriatric Research, Education, and Clinical Center, Ann Arbor Veterans Affairs Medical Center, Michigan, USA
Am J Geriatr Psychiatry 8:301-9. 2000..Although inpatient utilization appeared to be similar among races, findings related to outpatient utilization may be associated with such factors as compliance, treatment efficacy, access to health care, or possible clinician bias... - Herbal products and other supplements: use by elderly veterans with depression and dementia and their caregiversHelen C Kales
Psychiatry Service 116A, VA Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI, 48105, USA
J Geriatr Psychiatry Neurol 17:25-31. 2004..In light of the possibility of potentially harmful drug interactions, physicians who treat elderly patients should regularly inquire about the use of these products... - Recorded delirium in a national sample of elderly inpatients: potential implications for recognitionHelen C Kales
Serious Mental Illness Research and Evaluation Center Health Services Research and Development, Ann Arbor VA Medical Center, Ann Arbor, Michigan 48105, USA
J Geriatr Psychiatry Neurol 16:32-8. 2003..Future research should prospectively examine recognition of motoric and etiologic delirium subtypes and racial differences in delirium diagnoses... - Antidepressant treatment of veterans with Parkinson's disease and depression: analysis of a national samplePeijun Chen
Division of Geriatric Psychiatry, Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
J Geriatr Psychiatry Neurol 20:161-5. 2007..Efforts to improve the care of depressed PD patients should focus instead on improving recognition, ensuring adequacy of treatment, and evaluating the efficacy of existing antidepressants... - Depression in veterans with Parkinson's disease: frequency, co-morbidity, and healthcare utilizationPeijun Chen
Division of Geriatric Psychiatry, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
Int J Geriatr Psychiatry 22:543-8. 2007..To determine the frequency of depression in Parkinson's disease (PD) in routine clinical care, and to examine its association with co-morbid psychiatric and medical conditions and healthcare utilization... - Disruptive behaviors in Veterans Affairs nursing home residents: how different are residents with serious mental illness?John F McCarthy
Veterans Affairs National Serious Mental Illness Treatment Research and Evaluation Center, Health Services Research and Development, VA Ann Arbor Healthcare System, Ann Arbor, Michigan 48113, USA
J Am Geriatr Soc 52:2031-8. 2004..To determine the prevalence and correlates of behavior problems of residents of Veterans Affairs (VA) nursing homes and to compare residents with serious mental illness (SMI) with other resident groups... - Later-life depression and heart failureSusan M Maixner
Section of Geriatric Psychiatry, Department of Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48109 2700, USA
Heart Fail Clin 7:47-58. 2011.... - The effect of depression and cognitive impairment on enrollment in Medicare Part DKara Zivin
Serious Mental Illness Treatment Research and Evaluation Center, Department of Veterans Affairs, Ann Arbor, Michigan, USA
J Am Geriatr Soc 57:1433-40. 2009..To examine concerns that vulnerable populations, such as depressed or cognitively impaired beneficiaries would have challenges accessing Part D coverage... - Increases in Medicare prescription drug plan costs attributable to psychotropic medicationsKara Zivin
Department of Veterans Affairs, Health Services Research and Development HSR and D Center of Excellence, Serious Mental Illness Treatment Research and Evaluation Center SMITREC, Ann Arbor, MI, USA
Am J Geriatr Psychiatry 16:674-85. 2008..Patients' concerns about psychotropic medication costs under Medicare Part D may reinforce these impressions... - Adherence to depression treatment in older adults: a narrative reviewKara Zivin
National VA Serious Mental Illness Treatment, Research and Evaluation Center SMITREC, Ann Arbor, Michigan 48109, USA
Drugs Aging 25:559-71. 2008.... - Diagnosis and management of bipolar disorder with comorbid anxiety in the elderlyMartha Sajatovic
Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
J Clin Psychiatry 67:21-7. 2006..Unfortunately, few evidence-based studies are available to guide the treating clinician in the management of these vulnerable patients, many of whom have additional psychiatric or medical comorbidity... - Benzodiazepine use among depressed patients treated in mental health settingsMarcia Valenstein
Department of Veterans Affairs Medical Center, Serious Mental Illness Treatment, Research, and Evaluation Center, and Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
Am J Psychiatry 161:654-61. 2004..Elderly patients are particularly likely to receive benzodiazepines. Further research on the effectiveness of this widespread practice is needed... - Does consideration of Medicare use affect VA evaluations of treatment for new episodes of depression?John F McCarthy
HSR and D Field Program, VA Serious Mental Illness Treatment Research and Evaluation Center, PO Box 130170, Ann Arbor, MI 48113 0170, USA
Adm Policy Ment Health 35:468-76. 2008..Among the remainder, 3% received Medicare depression treatment and 0.5% were re-classified as having recommended contacts. Medicare use does not substantially supplement VA depression treatment... - Complexity in late-life depression: impact of confounding factors on diagnosis, treatment, and outcomesHelen C Kales
Department of Psychiatry, University of Michigan, Ann Arbor Veterans Affairs Medical Center 48105, USA
J Geriatr Psychiatry Neurol 15:147-55. 2002..Attention to such factors must be included in an agenda for mental health services research, with emphasis on the delivery of effective treatment to elderly patients with depression and improved outcomes in clinical settings... - Enhanced identification of eligibility for depression research using an electronic medical record search engineLisa Seyfried
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Int J Med Inform 78:e13-8. 2009..This was a prospective, observational study to compare the speed and clinical accuracy of a medical record search engine vs. manual review of the EMR... - Age-related modifiers of clinical presentation and health service use among veterans with bipolar disorderMartha Sajatovic
Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
Psychiatr Serv 55:1014-21. 2004.... - New-onset bipolar disorder in later lifeMartha Sajatovic
Dept of Psychiatry, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106, USA
Am J Geriatr Psychiatry 13:282-9. 2005..Selected differences were compared between new-onset and earlier-onset groups... - Criminal background checks for psychiatry? Michigan's mental health exceptionalismKara Zivin
J Am Acad Psychiatry Law 36:6-9. 2008 - Age comparison of treatment adherence with antipsychotic medications among individuals with bipolar disorderMartha Sajatovic
Psychiatry and Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Int J Geriatr Psychiatry 22:992-8. 2007..We compared adherence with antipsychotic medication among older (age 60 and older) and younger individuals using a large case registry (n = 73,964)... - Race and depression: does race affect the diagnosis and treatment of late-life depression?Helen C Kales
VA Ann Arbor Healthcare System and University of Michigan, USA
Geriatrics 61:18-21. 2006..This article reviews the current literature on racial differences in the diagnosis and treatment of late-life depression, including recent studies on physician contribution to disparities...
Research Grants
- 2/2-Personalized Antidepressant Adherence Strategies for Depressed EldersHelen C Kales; Fiscal Year: 2010..The purpose of this research is to test a personalized and flexible primary care-based program designed to help patients experience successful depression treatment. ..
- Racial Differences in Geriatric Antidepressant AdherenceHELEN KALES; Fiscal Year: 2007....
- Antipsychotics and Mortality in Older PatientsHELEN KALES; Fiscal Year: 2007..The results of this study will be of immediate relevance to clinicians and policymakers. ..
- Antipsychotics and Mortality in Older PatientsHELEN KALES; Fiscal Year: 2009..The results of this study will be of immediate relevance to clinicians and policymakers. ..