Research Topics
| A D KalechsteinSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Cocaine and methamphetamine produce different patterns of subjective and cardiovascular effectsThomas F Newton
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Semel Institute for Neuroscience and Human Behavior, Room A7 372, 740 Westwood Plaza, Los Angeles, CA 90024, USA
Pharmacol Biochem Behav 82:90-7. 2005..We predict that these differences may impact drug use and relapse patterns, and may have implications in medications development for these addictive disorders...
MDMA use and neurocognition: a meta-analytic reviewAri D Kalechstein
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at the University of California, Los Angeles, CA 90024, USA
Psychopharmacology (Berl) 189:531-7. 2007..To determine the association between MDMA misuse and neurocognition using meta-analysis...
Depression predicts procedural but not episodic memory in HIV-1 infectionA D Kalechstein
Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles Neuropsychiatric Institute and Hospital, USA
J Clin Exp Neuropsychol 20:529-35. 1998..These findings underscore the complex interplay between neuropsychiatric and neuropsychological symptomatology in HIV-1 infection...
Psychiatric comorbidity of methamphetamine dependence in a forensic sampleA D Kalechstein
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, California, USA
J Neuropsychiatry Clin Neurosci 12:480-4. 2000..These findings suggest that methamphetamine-dependent individuals are at greater risk to experience particular psychiatric symptoms. Further study to determine the etiology of these symptoms is warranted...
Apathy syndrome in cocaine dependenceAri D Kalechstein
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, UCLA Neuropsychiatric Institute, 760 Westwood Plaza, A7 372, Los Angeles, CA 90024, USA
Psychiatry Res 109:97-100. 2002..These data suggest that apathy is present during the initial phases of abstinence for a subset of cocaine-dependent individuals. This group may benefit from targeted pharmacological intervention...
Pathological gamblers demonstrate frontal lobe impairment consistent with that of methamphetamine-dependent individualsAri D Kalechstein
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA
J Neuropsychiatry Clin Neurosci 19:298-303. 2007..These findings demonstrate that the severity of frontal lobe dysfunction in pathological gambling is similar to that observed in methamphetamine-dependent individuals on frequently used clinical measures...
Methamphetamine dependence is associated with neurocognitive impairment in the initial phases of abstinenceAri D Kalechstein
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, School of Medicine, USA
J Neuropsychiatry Clin Neurosci 15:215-20. 2003....
Neurocognitive functioning is associated with employment status: a quantitative reviewA D Kalechstein
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA 90024, USA
J Clin Exp Neuropsychol 25:1186-91. 2003..These findings support the ecological validity of neurocognitive assessment...
Presence and persistence of psychotic symptoms in cocaine- versus methamphetamine-dependent participantsJames J Mahoney
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California, USA
Am J Addict 17:83-98. 2008..Future studies will compare psychotic symptoms reported by non-dependent recreational stimulant users to stimulant-dependent individuals...
Methamphetamine abstinence syndrome: preliminary findingsThomas F Newton
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA, USA
Am J Addict 13:248-55. 2004..The abstinence syndrome associated with methamphetamine dependence varied considerably in intensity and duration but generally was mild and resolved quickly for most individuals...
Association between quantitative EEG and neurocognition in methamphetamine-dependent volunteersThomas F Newton
Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, UCLA School of Medicine, Room A7 372, 760 Westwood Plaza, Los Angeles, CA 90024, USA
Clin Neurophysiol 115:194-8. 2004..Exposure to methamphetamine is associated with long-lasting reductions in markers for dopaminergic neurons in preclinical models and in humans. These changes may be associated with alterations in brain electrical activity and in cognition...
Irritability following abstinence from cocaine predicts euphoric effects of cocaine administrationThomas F Newton
Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, UCLA School of Medicine, Room A7 372, 760 Westwood Boulevard, Los Angeles, CA 90024, USA
Addict Behav 28:817-21. 2003..If these findings are replicated in a larger sample, then it may be necessary to reconsider the applicability of the opponent process model to cocaine addiction in humans...
Quantitative EEG abnormalities in recently abstinent methamphetamine dependent individualsThomas F Newton
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA, USA
Clin Neurophysiol 114:410-5. 2003....
Predicting adherence to treatment for methamphetamine dependence from neuropsychological and drug use variablesAndy C Dean
Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute, 760 Westwood Plaza, Box 951759, Los Angeles, CA 90095, USA
Drug Alcohol Depend 105:48-55. 2009..On the basis of these findings, we recommend that research groups seeking to identify new predictors of treatment outcome compare the predictors to methamphetamine usage variables to assure that unique predictive power is attained...
A qualitative and quantitative review of cocaine-induced craving: the phenomenon of primingJames J Mahoney
David Geffen School of Medicine at the University of California Los Angeles, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, United States
Prog Neuropsychopharmacol Biol Psychiatry 31:593-9. 2007..Clinical experience suggests that acute exposure to cocaine elicits craving (hereafter referred to as "priming"); however, this has received surprisingly little attention in the clinical literature...
Risperidone pre-treatment reduces the euphoric effects of experimentally administered cocaineT F Newton
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA 90024, USA
Psychiatry Res 102:227-33. 2001....
Apathy predicts hedonic but not craving response to cocaineThomas F Newton
David Geffen School of Medicine at the University of California Los Angeles, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA 90024, USA
Pharmacol Biochem Behav 82:236-40. 2005..The data reveal that cocaine-induced craving is not ubiquitous, and may not play a critical role in the maintenance of cocaine dependence. Overall, the findings suggest that apathy predicts hedonic but not craving response to cocaine...
Risperidone diminishes cocaine-induced cravingRichard De La Garza
Psychopharmacology (Berl) 178:347-50. 2005
Research Grants
- Methamphetamine Dependence: Treating Cognition DisorderAri Kalechstein; Fiscal Year: 2005....
