Sanjay Kakar

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Loss of heterozygosity, aberrant methylation, BRAF mutation and KRAS mutation in colorectal signet ring cell carcinoma
    Sanjay Kakar
    Department of Pathology, Veteran Affairs Medical Center and University of California, San Francisco, San Francisco, CA, USA
    Mod Pathol 25:1040-7. 2012
  2. pmc Chromosomal abnormalities determined by comparative genomic hybridization are helpful in the diagnosis of atypical hepatocellular neoplasms
    Sanjay Kakar
    Department of Pathology, University of California, San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    Histopathology 55:197-205. 2009
  3. doi request reprint Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization
    Sanjay Kakar
    Department of Pathology, University of California, San Francisco, CA, USA
    Mod Pathol 22:134-41. 2009
  4. doi request reprint Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability
    Sanjay Kakar
    Department of Pathology, Veterans Affairs Medical Center and University ofCalifornia at San Francisco, San Francisco, Calif, USA
    Arch Pathol Lab Med 132:958-64. 2008
  5. ncbi request reprint CpG island methylation is frequently present in tubulovillous and villous adenomas and correlates with size, site, and villous component
    Sanjay Kakar
    Department of Pathology, Veteran Affairs Medical Center and University of California at San Francisco, San Francisco, CA 94121, USA
    Hum Pathol 39:30-6. 2008
  6. ncbi request reprint Best practices in diagnostic immunohistochemistry: hepatocellular carcinoma versus metastatic neoplasms
    Sanjay Kakar
    Department of Pathology, Veteran Affairs and University of California Medical Center, San Francisco, CA 94121, USA
    Arch Pathol Lab Med 131:1648-54. 2007
  7. ncbi request reprint BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer
    Hirofumi Tanaka
    Department of Medicine, Gastrointestinal Research Laboratory, Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA 94121, USA
    Int J Cancer 118:2765-71. 2006
  8. ncbi request reprint Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelines
    Fernando S Velayos
    Division of Gastroenterology and Colorectal Cancer Prevention Program, University of California, San Francisco, CA, USA
    Am J Gastroenterol 100:1143-9. 2005
  9. ncbi request reprint MUC2 gene promoter methylation in mucinous and non-mucinous colorectal cancer tissues
    Keisuke Okudaira
    Department of Medicine, Gastrointestinal Research Laboratory, Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA, USA
    Int J Oncol 36:765-75. 2010
  10. doi request reprint Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics
    Guoren Deng
    Gastrointestinal Research Laboratory 151M2, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Eur J Cancer 44:1290-301. 2008

Collaborators

Detail Information

Publications54

  1. doi request reprint Loss of heterozygosity, aberrant methylation, BRAF mutation and KRAS mutation in colorectal signet ring cell carcinoma
    Sanjay Kakar
    Department of Pathology, Veteran Affairs Medical Center and University of California, San Francisco, San Francisco, CA, USA
    Mod Pathol 25:1040-7. 2012
    ..The high frequency of methylation and BRAF V600E mutation suggests that many signet ring cell carcinomas may be related to the serrated pathway of carcinogenesis...
  2. pmc Chromosomal abnormalities determined by comparative genomic hybridization are helpful in the diagnosis of atypical hepatocellular neoplasms
    Sanjay Kakar
    Department of Pathology, University of California, San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    Histopathology 55:197-205. 2009
    ..To explore the utility of cytogenetic abnormalities in the distinction of hepatic adenoma (HA) and well-differentiated hepatocellular carcinoma (HCC)...
  3. doi request reprint Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization
    Sanjay Kakar
    Department of Pathology, University of California, San Francisco, CA, USA
    Mod Pathol 22:134-41. 2009
    ..The favorable outcome in some fibrolamellar carcinomas may be due to absent or low number of cytogenetic aberrations...
  4. doi request reprint Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability
    Sanjay Kakar
    Department of Pathology, Veterans Affairs Medical Center and University ofCalifornia at San Francisco, San Francisco, Calif, USA
    Arch Pathol Lab Med 132:958-64. 2008
    ..The 2 chief pathways implicated in colorectal carcinogenesis, microsatellite instability and chromosomal instability, are not present in 20% to 37% of cases...
  5. ncbi request reprint CpG island methylation is frequently present in tubulovillous and villous adenomas and correlates with size, site, and villous component
    Sanjay Kakar
    Department of Pathology, Veteran Affairs Medical Center and University of California at San Francisco, San Francisco, CA 94121, USA
    Hum Pathol 39:30-6. 2008
    ..Methylation of MGMT and RASSF2 increases during the progression from tubular adenoma to tubulovillous/villous adenoma. BRAF mutations are absent in tubulovillous/villous adenomas...
  6. ncbi request reprint Best practices in diagnostic immunohistochemistry: hepatocellular carcinoma versus metastatic neoplasms
    Sanjay Kakar
    Department of Pathology, Veteran Affairs and University of California Medical Center, San Francisco, CA 94121, USA
    Arch Pathol Lab Med 131:1648-54. 2007
    ..Because limited tissue is available with fine-needle and core biopsies, appropriate selection of antibodies is imperative...
  7. ncbi request reprint BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer
    Hirofumi Tanaka
    Department of Medicine, Gastrointestinal Research Laboratory, Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA 94121, USA
    Int J Cancer 118:2765-71. 2006
    ..01). The more frequent occurrence and closer association among MSI, CIMP and BRAF mutation in mucinous CRC observed in our study further supports the idea that its pathogenesis may involve distinct genetic and epigenetic changes...
  8. ncbi request reprint Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelines
    Fernando S Velayos
    Division of Gastroenterology and Colorectal Cancer Prevention Program, University of California, San Francisco, CA, USA
    Am J Gastroenterol 100:1143-9. 2005
    ..We sought to determine the rate of MSI in adenomas removed from individuals under 40 yr of age over a 5-yr period in a university general gastroenterology practice...
  9. ncbi request reprint MUC2 gene promoter methylation in mucinous and non-mucinous colorectal cancer tissues
    Keisuke Okudaira
    Department of Medicine, Gastrointestinal Research Laboratory, Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA, USA
    Int J Oncol 36:765-75. 2010
    ..We concluded that low methylation status of MUC2 gene plays a predominant role in high level MUC2 expression in mucinous CRC...
  10. doi request reprint Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics
    Guoren Deng
    Gastrointestinal Research Laboratory 151M2, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Eur J Cancer 44:1290-301. 2008
    ..However, the frequency and the pattern of these alterations in proximal and distal colon cancers have not been examined in detail...
  11. ncbi request reprint Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum
    Dong Hoon Kim
    Gastrointestinal Research Laboratory, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Int J Oncol 27:957-64. 2005
    ....
  12. ncbi request reprint Signet ring cell carcinoma of the colorectum: correlations between microsatellite instability, clinicopathologic features and survival
    Sanjay Kakar
    Department of Pathology, University of California San Francisco, Veteran Affairs Medical Center, San Francisco, CA, USA
    Mod Pathol 18:244-9. 2005
    ..Microsatellite instability status does not appear to be a significant predictor of survival in signet ring cell carcinoma of the colorectum...
  13. ncbi request reprint Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs
    Guoren Deng
    Gastrointestinal Research Laboratory 151M2, Veteran Affairs Medical Center of San Francisco, Department of Medicine, University of California San Franicisco, San Francisco, CA 94121, USA
    Clin Cancer Res 15:1519-26. 2009
    ..In melanoma cells, epigenetic silencing of OSM receptor (OSMR) by histone deacetylation contributes to escape of cell growth control by OSM. However, the silencing of OSMR by DNA methylation in any cancer has not been examined...
  14. ncbi request reprint Mucinous carcinoma of the colon: correlation of loss of mismatch repair enzymes with clinicopathologic features and survival
    Sanjay Kakar
    Department of Pathology, University of California San Francisco and Veteran Affairs Medical Center, San Francisco, CA, USA
    Mod Pathol 17:696-700. 2004
    ..The outcome for MSI-H mucinous carcinoma is better than that of microsatellite-stable mucinous carcinoma, but MSI status is not an independent predictor of survival...
  15. ncbi request reprint The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer
    Koji Matsuzaki
    Department of Medicine, Gastrointestinal Research Laboratory, Veteran Affairs Medical Center, Medicine and Anatomic Pathology, University of California San Francisco, San Francisco, California 94121, USA
    Clin Cancer Res 11:8564-9. 2005
    ..The aim of this study was to investigate the relationship between global methylation status, loss of heterozygosity (LOH), and MSI in sporadic colorectal cancer...
  16. doi request reprint Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps
    Yong Ho Kim
    Gastrointestinal Research Laboratory 151M2, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Int J Cancer 123:2587-93. 2008
    ..BRAF mutation occurs independently of CIMP and MSI in all types of serrated polyps and may serve as a marker of serrated pathway of colorectal carcinogenesis...
  17. doi request reprint Tumor histology helps to identify Lynch syndrome among colorectal cancer patients
    Brindusa Truta
    Department of Medicine, Gastroenterology Division, University California San Francisco, 2330 Post St, Suite 610, San Francisco, CA 94115, USA
    Fam Cancer 7:267-74. 2008
    ..To determine the value of histology in identifying Lynch syndrome among those patients with early onset of colorectal cancer (CRC)...
  18. ncbi request reprint Mucinous carcinomas of the colorectum have distinct molecular genetic characteristics
    Geun Am Song
    Gastrointestinal Research Laboratory, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Int J Oncol 26:745-50. 2005
    ..11%, p=0.01). These results indicate that mucinous carcinomas of the colorectum exhibit distinct molecular genetic characteristics and may arise from distinct pathogenic pathways...
  19. ncbi request reprint Contributions to hepatic fibrosis in HIV-HCV coinfected and HCV monoinfected patients
    Alexander Monto
    Gastroenterology Section, Veterans Affairs Medical Center, San Francisco, California 94121, USA
    Am J Gastroenterol 101:1509-15. 2006
    ..The aim of this study was to further explore the severity of liver disease and its predictors in a cohort of hepatitis C virus (HCV) infected patients, some of whom were coinfected with the human immunodeficiency virus (HIV)...
  20. ncbi request reprint Aberrant expression of SOX2 upregulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorectum and related lesions
    Eun Taek Park
    Gastrointestinal Research Laboratory, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Int J Cancer 122:1253-60. 2008
    ..In addition, the expression of both SOX2 and MUC5AC in serrated polyps supports the hypothesis that these polyps may be predominant precursors of mucinous and signet ring cell carcinomas of the colorectum...
  21. doi request reprint Utility and limitations of glypican-3 expression for the diagnosis of hepatocellular carcinoma at both ends of the differentiation spectrum
    Nafis Shafizadeh
    Department of Anatomic Pathology, University of California, San Francisco, CA 94121, USA
    Mod Pathol 21:1011-8. 2008
    ..Glypican-3 can be especially useful in the identification of poorly differentiated hepatocellular carcinoma as it has higher sensitivity compared to Hep Par 1...
  22. ncbi request reprint Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis
    Sanjay Kakar
    Department of Anatomic Pathology, UCSF VA Medical Center, San Francisco, CA 94121, USA
    Mod Pathol 18:1417-23. 2005
    ..The better outcome in fibrolamellar carcinoma appears to be due to the absence of cirrhosis rather than its distinct clinicopathologic features...
  23. ncbi request reprint Chromosomal instability in microsatellite-unstable and stable colon cancer
    Karolin Trautmann
    Comprehensive Cancer Center, Department of Medicine, University of California San Francisco, San Francisco, California 94143 0808, USA
    Clin Cancer Res 12:6379-85. 2006
    ....
  24. ncbi request reprint HATH1 expression in mucinous cancers of the colorectum and related lesions
    Eun Taek Park
    Gastrointestinal Research Laboratory, Department of Medicine, Veterans Affairs Medical Center, University of California San Francisco, San Francisco, California 94121, USA
    Clin Cancer Res 12:5403-10. 2006
    ..The aim of this study was to assess the possible role of HATH1 in the development of mucinous cancers and signet ring carcinomas...
  25. doi request reprint Epidermal growth factor receptor expression and gene copy number in conventional hepatocellular carcinoma
    Anne F Buckley
    Departments of Pathology, UCSF and Veteran Affairs Medical Centers, San Francisco, CA 94121, USA
    Am J Clin Pathol 129:245-51. 2008
    ..EGFR overexpression is present in a majority of hepatocellular carcinomas, suggesting a role for EGFR antagonists in therapy. The increased expression does not correlate with an increase in the EGFR gene copy number...
  26. ncbi request reprint Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinoma
    Anne F Buckley
    Department of Pathology, Veteran Affairs and UCSF Medical Center, San Francisco, CA 94143, USA
    Hum Pathol 37:410-4. 2006
    ..The strong expression of EGFR in FL-HCC tumors suggests that they may respond to treatment with EGFR antagonists...
  27. pmc S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis
    Wei Wei
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Sci Transl Med 2:19ra13. 2010
    ..Thus, our data suggest that GSNOR deficiency, through dysregulated S-nitrosylation, may promote HCC, possibly by inactivating a DNA repair system...
  28. doi request reprint Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder
    Nafis Shafizadeh
    Department of Pathology, University of California, San Francisco, CA 94121, USA
    Hum Pathol 41:485-92. 2010
    ..02). HER2/neu expression is uncommon in these tumors...
  29. doi request reprint Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma
    Gregor Krings
    Department of Pathology, University of California, San Francisco, San Francisco, CA, USA
    Mod Pathol 26:782-91. 2013
    ..Glypican 3 and arginase are the most reliable markers for identifying hepatocellular differentiation in this setting...
  30. doi request reprint Reticulin loss in benign fatty liver: an important diagnostic pitfall when considering a diagnosis of hepatocellular carcinoma
    Aatur D Singhi
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Surg Pathol 36:710-5. 2012
    ..Increased awareness of this important diagnostic pitfall will help prevent overcalling of reticulin loss when evaluating biopsies and resections of hepatic neoplasms with fatty change...
  31. ncbi request reprint Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma
    Mohini A Patil
    Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143, USA
    Carcinogenesis 26:2050-7. 2005
    ....
  32. doi request reprint Diagnostic utility and limitations of glutamine synthetase and serum amyloid-associated protein immunohistochemistry in the distinction of focal nodular hyperplasia and inflammatory hepatocellular adenoma
    Nancy M Joseph
    Department of Anatomic Pathology, University of California, San Francisco, CA, USA
    Mod Pathol 27:62-72. 2014
    ..Our results highlight the diagnostic errors that can be caused by variant patterns of staining with glutamine synthetase and serum amyloid-associated protein in inflammatory hepatocellular adenoma and focal nodular hyperplasia. ..
  33. doi request reprint Atypical hepatocellular adenoma-like neoplasms with β-catenin activation show cytogenetic alterations similar to well-differentiated hepatocellular carcinomas
    Kimberley J Evason
    Department of Pathology and Liver Center, University of California, San Francisco, CA 94143, USA
    Hum Pathol 44:750-8. 2013
    ..The similarity in morphologic and cytogenetic features of β-catenin-activated hepatocellular adenoma-like tumors and HCC suggests that the former tumors represent an extremely well-differentiated variant of HCC...
  34. pmc MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer
    Seong O Suh
    Department of Urology, Veterans Affairs Medical Center and University of California at San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    Carcinogenesis 32:772-8. 2011
    ..The apoptotic cells are increased after WT p53 transfection. In summary, this is the first report documenting that downregulation of miR-145 is through DNA methylation and p53 mutation pathways in prostate cancer...
  35. ncbi request reprint Comparison of the Dako EGFR pharmDx kit and Zymed EGFR antibody for assessment of EGFR status in colorectal adenocarcinoma
    Anne F Buckley
    Department of Pathology, UCSF, San Francisco, CA, USA
    Appl Immunohistochem Mol Morphol 15:305-9. 2007
    ..There is little justification for the use of expensive kits for testing EGFR expression, when other available antibodies without the kit can give comparable or superior results...
  36. ncbi request reprint Association of large serrated polyps with synchronous advanced colorectal neoplasia
    Dan Li
    Department of Medicine, University of California, San Francisco, 94115, USA
    Am J Gastroenterol 104:695-702. 2009
    ..Accumulating evidence suggests that they may have different malignancy potentials. This study sought to determine the association between the presence of large serrated colorectal polyps and synchronous advanced colorectal neoplasia...
  37. ncbi request reprint Prognostic significance of DCC and p27Kip1 in colorectal cancer
    James T Wu
    Department of Pathology, University of Illinois, Chicago, Medical Center, Chicago, IL, USA
    Appl Immunohistochem Mol Morphol 13:45-54. 2005
    ..87; 95% confidence interval, 0.58-1.29; P=0.49). The present study demonstrated that the expression of neither DCC nor p27Kip1 was predictive in poor survival outcome in patients with stage II or III colorectal cancer...
  38. ncbi request reprint Accuracy of liver fat quantification at MR imaging: comparison of out-of-phase gradient-echo and fat-saturated fast spin-echo techniques--initial experience
    Aliya Qayyum
    Department of Radiology, University of California San Francisco, CA 94143 0628, USA
    Radiology 237:507-11. 2005
    ....
  39. ncbi request reprint Sinusoidal dilatation and congestion in liver biopsy: is it always due to venous outflow impairment?
    Sanjay Kakar
    Department of Pathology, Veteran Affairs and University of California Medical Center, San Francisco, Calif, USA
    Arch Pathol Lab Med 128:901-4. 2004
    ..Objectives.-To determine the specificity of SDC in liver biopsies for venous outflow impairment and to seek an explanation for SDC in patients without clinical or radiologic features of venous outflow impairment...
  40. doi request reprint Protocol for the examination of specimens from patients with primary carcinomas of the colon and rectum
    Mary Kay Washington
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232 2561, USA
    Arch Pathol Lab Med 132:1182-93. 2008
  41. ncbi request reprint Mice expressing SV40 T antigen directed by the intestinal trefoil factor promoter develop tumors resembling human small cell carcinoma of the colon
    James R Gum
    Department of Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Mol Cancer Res 2:504-13. 2004
    ..ITFTag tumors closely resemble human small cell carcinomas of the colon, suggesting the possibility that these tumors might be derived from the enteroendocrine cell lineage as well...
  42. pmc Hepatic fibrosis: evaluation with semiquantitative contrast-enhanced CT
    Vanja Varenika
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Ave, Box 0628, M 372, San Francisco, CA 94143 0628, USA
    Radiology 266:151-8. 2013
    ....
  43. doi request reprint Diagnosis of well-differentiated hepatocellular lesions: role of immunohistochemistry and other ancillary techniques
    Nafis Shafizadeh
    Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, USA
    Adv Anat Pathol 18:438-45. 2011
    ..Combined use of heat shock protein 70, glutamine synthetase, and glypican-3 can be useful as positivity for 2 or more of these markers has shown high specificity for HCC in early studies...
  44. ncbi request reprint Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury
    Gene S Lee
    Liver Center, University of California, San Francisco, San Francisco, CA 94110, USA
    J Lipid Res 48:1885-96. 2007
    ..These findings emphasize that individual dietary nutrients can make specific contributions to steatohepatitis...
  45. ncbi request reprint Frequency of loss of hMLH1 expression in colorectal carcinoma increases with advancing age
    Sanjay Kakar
    Department of Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 97:1421-7. 2003
    ..The correlation between age at diagnosis and loss of expression of hMLH1 protein in patients with colorectal carcinoma (CRC) has not been evaluated systematically...
  46. ncbi request reprint Histologic changes mimicking biliary disease in liver biopsies with venous outflow impairment
    Sanjay Kakar
    Department of Pathology, Veteran Affairs and University of California Medical Center, San Francisco, CA, USA
    Mod Pathol 17:874-8. 2004
    ..In the absence of demonstrable abnormalities in the biliary tree, these changes can be attributed to venous outflow impairment...
  47. ncbi request reprint Significance of intraepithelial lymphocytosis in small bowel biopsy samples with normal mucosal architecture
    Sanjay Kakar
    Department of Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Gastroenterol 98:2027-33. 2003
    ....
  48. ncbi request reprint Colonic ulcers accompanying collagenous colitis: implication of nonsteroidal anti-inflammatory drugs
    Sanjay Kakar
    Department of Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Gastroenterol 98:1834-7. 2003
    ..We studied the association of CC-U cases with ingestion of nonsteroidal anti-inflammatory drugs (NSAIDs) as a possible explanation for the mucosal ulceration...
  49. ncbi request reprint Hepatic steatosis in HIV/hepatitis C coinfection: prevalence and significance compared with hepatitis C monoinfection
    Alexander Monto
    Gastroenterology Section, Veterans Affairs Medical Center, University of California, 4150 Clement Street 111B, San Francisco, CA 94121, USA
    Hepatology 42:310-6. 2005
    ..In conclusion, steatosis is less common in HIV/HCV coinfected patients than similar HCV monoinfected patients, and predictors of steatosis differ between the two groups...
  50. ncbi request reprint Management of patients with metastatic cancer of unknown primary
    Luna Ghosh
    Pathology, State University of New York Brooklyn, Brooklyn, NY, USA
    Curr Probl Surg 42:12-66. 2005
  51. ncbi request reprint Immunoreactivity of Hep Par 1 in hepatic and extrahepatic tumors and its correlation with albumin in situ hybridization in hepatocellular carcinoma
    Sanjay Kakar
    Department of Pathology, Mayo Clinic, Rochester, MN
    Am J Clin Pathol 119:361-6. 2003
    ..Cholangiocarcinoma and carcinomas from most other sites are negative for Hep Par 1. Hep Par 1 immunoreactivity shows high correlation with albumin ISH; their combined use for diagnosis of HCC had a sensitivity of 100% in this population...
  52. ncbi request reprint Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer
    Guoren Deng
    Gastrointestinal Research Laboratory, Veteran Affairs Medical Center and Department of Medicine, University of California San Francisco, 94121, USA
    Int J Cancer 118:2999-3005. 2006
    ....
  53. ncbi request reprint Origin of adenocarcinoma in a transplanted liver determined by microsatellite analysis
    Sanjay Kakar
    Division of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 33:435-6. 2002
    ..The allelic patterns of tumor DNA were identical to those of donor DNA and were distinct from the DNA profile of the recipient. The use of MS analysis clearly established that the adenocarcinoma was of donor origin...
  54. ncbi request reprint The fate of low grade dysplasia in ulcerative colitis
    Thomas A Ullman
    The Dr Henry D Janowitz Division of Gastroenterology, Mount Sinai School of Medicine, New York, New York, USA
    Am J Gastroenterol 97:922-7. 2002
    ..The optimal strategy for the management of definite low grade dysplasia (LGD) detected in surveillance in ulcerative colitis (UC) is unknown, because the natural history of LGD has not been well described...