Research Topics
| Jeremy KahnSummaryAffiliation: University of Pennsylvania Country: USA Publications
Research Grants
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Detail Information
Publications
Transferring critically ill patients out of hospital improves the standardized mortality ratio: a simulation studyJeremy M Kahn
Division of Pulmonary and Critical Care, Harborview Medical Center, University of Washington, Seattle WA, USA
Chest 131:68-75. 2007..We sought to quantify the effect of out-of-hospital transfers on the standardized mortality ratio (SMR), an outcome-based measure of ICU performance...
Intensivist physician staffing and the process of care in academic medical centresJeremy M Kahn
Division of Pulmonary, Allergy and Critical Care Medicine, Center for Clinical Epidemiology and Biostatistics, and the Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Qual Saf Health Care 16:329-33. 2007..Although intensivist physician staffing is associated with improved outcomes in critical care, little is known about the mechanism leading to this observation...- Barriers to implementing the Leapfrog Group recommendations for intensivist physician staffing: a survey of intensive care unit directorsJeremy M Kahn
Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98119, USA
J Crit Care 22:97-103. 2007..The purpose of this study was to examine the perception of the Leapfrog standards among ICU directors and determine the potential barriers to implementing these standards... - The structure of critical care transfer networksTheodore J Iwashyna
Division of Pulmonary and Critical Care, Department of Medicine, University of Michigan, Ann Arbor, MI 48109, USA
Med Care 47:787-93. 2009..These transfers may be particularly important in critical care, where small relative improvements can yield substantial absolute changes in survival... - Uncharted paths: hospital networks in critical careTheodore J Iwashyna
Division of Pulmonary and Critical Care, Department of Medicine, University of Michigan, Ann Arbor, MI 48109, USA
Chest 135:827-33. 2009.... - Hospital volume and the outcomes of mechanical ventilationJeremy M Kahn
Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle 98104, USA
N Engl J Med 355:41-50. 2006..Further research is needed to determine the mechanism of the relationship between volume and outcome among patients with a critical illness. Copyright 2006 Massachusetts Medical Society... - Acute lung injury in patients with subarachnoid hemorrhage: incidence, risk factors, and outcomeJeremy M Kahn
Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA, USA
Crit Care Med 34:196-202. 2006..Research is needed to determine the causes of acute lung injury in this population and whether these patients are candidates for evidence-based ventilator strategies to reduce mortality... 
The effect of multidisciplinary care teams on intensive care unit mortalityMichelle M Kim
Department of Health Care Management and Economics, Wharton School of Business, University of Pennsylvania, Philadelphia, PA 19104, USA
Arch Intern Med 170:369-76. 2010..Critically ill patients are medically complex and may benefit from a multidisciplinary approach to care...- Physician attitudes toward regionalization of adult critical care: a national surveyJeremy M Kahn
Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Crit Care Med 37:2149-54. 2009..Regionalization has been proposed as a method to improve outcomes for patients with critical illness. We sought to determine intensivist physician attitudes and potential barriers to the regionalization of adult critical care... - Regionalization of medical critical care: what can we learn from the trauma experience?Jeremy M Kahn
Division of Pulmonary, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Crit Care Med 36:3085-8. 2008..To review the rationale for the regionalization of adult critical care and discuss how lessons from the trauma experience may be relevant to this debate... - Inter-hospital variability in post-cardiac arrest mortalityBrendan G Carr
The Robert Wood Johnson Clinical Scholars Program, University of Pennsylvania School of Medicine UPENN SOM, USA
Resuscitation 80:30-4. 2009..We examined hospital-level variation in mortality of patients admitted to United States intensive care units (ICUs) with a diagnosis of cardiac arrest... - The impact of development of acute lung injury on hospital mortality in critically ill trauma patientsChirag V Shah
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
Crit Care Med 36:2309-15. 2008..We assessed the contribution of acute lung injury to in-hospital mortality in critically ill trauma patients... - Perceived barriers to the regionalization of adult critical care in the United States: a qualitative preliminary studyJeremy M Kahn
Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
BMC Health Serv Res 8:239. 2008..We sought to develop a framework for understanding clinician attitudes toward regionalization and potential barriers to developing a tiered, regionalized system of care in the United States... - Disseminating clinical trial results in critical careJeremy M Kahn
Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania School of Medicine, Philadelphia PA, USA
Crit Care Med 37:S147-53. 2009..It is essential that investigators conducting clinical trials prioritize knowledge transfer to ensure that new therapies in critical care are actually reaching the critically ill... - Effect of work-hours regulations on intensive care unit mortality in United States teaching hospitalsMeeta Prasad
Division of Pulmonary, Allergy, and Critical Care Medicine MP, JDC, JMK, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Crit Care Med 37:2564-9. 2009..The United States instituted restrictions on resident work-hours in July 2003. The clinical impact of this reform on critically ill patients is unknown... - Predictors of hospital mortality in a population-based cohort of patients with acute lung injuryColin R Cooke
Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98104, USA
Crit Care Med 36:1412-20. 2008..We sought to determine the predictors of mortality in a population-based cohort of patients with acute lung injury and to characterize the performance of current severity of illness scores in this population... - Potential value of regionalized intensive care for mechanically ventilated medical patientsJeremy M Kahn
Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, 723 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
Am J Respir Crit Care Med 177:285-91. 2008..Regionalization has been proposed as a method to improve outcomes for medical patients receiving mechanical ventilation in the intensive care unit... - Accuracy of the discharge destination field in administrative data for identifying transfer to a long-term acute care hospitalJeremy M Kahn
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Blockley Hall 723, 423 Guardian Drive, Philadelphia, PA 19104
BMC Res Notes 3:205. 2010.... - Long-term acute care hospital utilization after critical illnessJeremy M Kahn
Division of Pulmonary, Allergy, and Critical Care, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Blockley Hall 723, 423 Guardian Dr, Philadelphia, PA 19104, USA
JAMA 303:2253-9. 2010..Long-term acute care hospitals have emerged as a novel approach for the care of patients recovering from severe acute illness, but the extent and increases in their activity at the national level are unknown... - The availability of clinical protocols in US teaching intensive care unitsMeeta Prasad
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Crit Care 25:610-9. 2010..Clinical protocols to standardize care may improve patient outcomes but worsen trainee education. Our objective was to determine the availability of clinical protocols in teaching medical intensive care units (ICUs)... - Cost savings attributable to reductions in intensive care unit length of stay for mechanically ventilated patientsJeremy M Kahn
Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Med Care 46:1226-33. 2008.... - The relationship between hospital volume and mortality in mechanical ventilation: an instrumental variable analysisJeremy M Kahn
Division of Pulmonary, Allergy and Critical Care, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 723 Blockley Hall, Philadelphia, PA 19104, USA
Health Serv Res 44:862-79. 2009..To examine the relationship between hospital volume and mortality for nonsurgical patients receiving mechanical ventilation... - Volume, outcome, and the organization of intensive careJeremy M Kahn
Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania School of Medicine, 723 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
Crit Care 11:129. 2007..Future research efforts should be directed at better characterizing the process of care in high-volume ICUs and exploring the feasibility of creating a regionalized system of care... - Health policy and future planning for survivors of critical illnessJeremy M Kahn
Division of Pulmonary, Allergy and Critical Care, Leonard Davis Institute of Health Economics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, USA
Curr Opin Crit Care 13:514-8. 2007..This review will assess some of the health system-level barriers to effective post-intensive care unit care and provide a framework for policy decisions directed at improving outcomes for survivors of critical illness... - Identifying and implementing quality improvement measures in the intensive care unitJeremy M Kahn
Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Curr Opin Crit Care 13:709-13. 2007..We review recent advances in the field of quality improvement and discuss some of the challenges to successful quality improvement initiatives in critical care... - Critical illness outcomes in specialty versus general intensive care unitsJason P Lott
University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Am J Respir Crit Care Med 179:676-83. 2009..General intensive care units (ICUs) provide care across a wide range of diagnoses, whereas specialty ICUs provide diagnosis-specific care. Risk-adjusted outcome differences across such units are unknown... - Adverse events during rotary-wing transport of mechanically ventilated patients: a retrospective cohort studyChristopher W Seymour
Division of Pulmonary and Critical Care, University of Washington School of Medicine, Campus Box 356522, Seattle, WA 98195 6522, USA
Crit Care 12:R71. 2008..The incidence of physiologic adverse events and their predisposing factors in mechanically ventilated patients undergoing aeromedical transport are unknown... - Cost-effectiveness of implementing low-tidal volume ventilation in patients with acute lung injuryColin R Cooke
Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98104, USA
Chest 136:79-88. 2009..We sought to estimate the incremental clinical and economic outcomes associated with LPV and determined the maximum cost of a hypothetical intervention to improve adherence with LPV that remained cost-effective... - Prediction of critical illness during out-of-hospital emergency careChristopher W Seymour
Division of Pulmonary and Critical Care Medicine, University of Washington, Harborview Medical Center, PO Box 359762, Seattle, WA 98104, USA
JAMA 304:747-54. 2010..Early identification of nontrauma patients in need of critical care services in the emergency setting may improve triage decisions and facilitate regionalization of critical care... - The effect of an intensive care unit staffing model on tidal volume in patients with acute lung injuryColin R Cooke
Division of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Harborview Medical Center, 325 9th Avenue, Box 359762, Seattle, Washington, 98104, USA
Crit Care 12:R134. 2008..We aimed to assess the effect of closed-model intensive care on evidence-based ventilatory practice in patients with acute lung injury (ALI)... - Understanding economic outcomes in critical careJeremy M Kahn
Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, Washington 98119, USA
Curr Opin Crit Care 12:399-404. 2006..Costs are markedly different than other clinical outcomes, both in their measurement and their interpretation... - Translating evidence into practice in the intensive care unit: the need for a systems-based approachJeremy M Kahn
Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA 98104, USA
J Crit Care 20:204-6. 2005 - Low tidal volume ventilation does not increase sedation use in patients with acute lung injuryJeremy M Kahn
Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
Crit Care Med 33:766-71. 2005..Sedation administration should not be considered a barrier to implementing a lung-protective ventilation strategy... - Stress ulcer prophylaxis in mechanically ventilated patients: integrating evidence and judgment using a decision analysisJeremy M Kahn
Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98119, USA
Intensive Care Med 32:1151-8. 2006..gastrointestinal bleeding will have a significant effect on the decision... - Prioritizing the organization and management of intensive care services in the United States: the PrOMIS ConferenceAmber E Barnato
Center for Research on Health Care, and the CRISMA Laboratory Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Crit Care Med 35:1003-11. 2007..We sought to elicit the perceived problems and solutions to the delivery of critical care services from a broad set of U.S. stakeholders... - Improving sepsis care: the road aheadJeremy M Kahn
JAMA 299:2322-3. 2008 - Building a better intensive care unit: the role of industrial process improvement in critical careJeremy M Kahn
Respir Care 53:858-9. 2008 - Reducing the cost of critical care: new challenges, new solutionsJeremy M Kahn
Am J Respir Crit Care Med 174:1167-8. 2006
Research Grants
- Development and validation of an Instrument to Measure Critical Care OrganizationJeremy Kahn; Fiscal Year: 2007..The instrument generated in this research will be used in future studies examining specific interventions to improve ICU organization. (End of Abstract) ..
- The role of long term acute care hospitals in prolonged mechanical ventilationJeremy M Kahn; Fiscal Year: 2010..This project will directly inform key clinical and health policy decisions about long-term acute care hospitals and the care of patients with PMV. ..
- The Effect of Patient Volume on Outcome in the ICUJeremy Kahn; Fiscal Year: 2006..A greater understanding of the effects of volume on critical care outcome will guide future investigations into the processes of care at high volume centers that may determine the volume-outcome relationship. ..