Research Topics
| A JustSummaryAffiliation: University of North Carolina Country: USA Publications
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Publications
Dual constrictor and dilator actions of ET(B) receptors in the rat renal microcirculation: interactions with ET(A) receptorsArmin Just
Dept of Cell and Molecular Physiology, 6341 Medical Biomolecular Research Bldg, CB 7545, School of Medicine, Univ of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7545, USA
Am J Physiol Renal Physiol 286:F660-8. 2004..Possible explanations include ET-1 clearance by ET(B) receptors and/or a dilator ET(B) receptor function that counteracts constriction...
Nitric oxide blunts myogenic autoregulation in rat renal but not skeletal muscle circulation via tubuloglomerular feedbackArmin Just
Department of Cell and Molecular Physiology, 6341 Medical Biomolecular Research Bldg, CB 7545, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7545, USA
J Physiol 569:959-74. 2005..We conclude that NO normally restrains the strength and speed of the myogenic response in RBF but not hindlimb autoregulation, an action dependent on TGF, thereby allowing more and slow RAP fluctuations to reach glomerular capillaries...- Superoxide mediates acute renal vasoconstriction produced by angiotensin II and catecholamines by a mechanism independent of nitric oxideArmin Just
Dept of Cell and Molecular Physiology, 6341 Medical Biomolecular Research Bldg, CB 7545, School of Medicine, Univ of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7545, USA
Am J Physiol Heart Circ Physiol 292:H83-92. 2007..These effects are due to O(2)(-) rather than H(2)O(2), occur rapidly, and are independent of scavenging of NO... - Dynamics and contribution of mechanisms mediating renal blood flow autoregulationArmin Just
Dept of Cell and Molecular Physiology, 6341 Medical Biomolecular Research Bldg, CB 7545, School of Medicine, Univ of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7545, USA
Am J Physiol Regul Integr Comp Physiol 285:R619-31. 2003..The data suggest a third regulatory system contributing <12% normally but up to 50% at low RAP; its nature awaits further investigation... - Mechanisms of renal blood flow autoregulation: dynamics and contributionsArmin Just
Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7545, USA
Am J Physiol Regul Integr Comp Physiol 292:R1-17. 2007..NO attenuates the strength, speed, and contribution of MR, whereas ANG II does not modify the balance of the autoregulatory mechanisms... - A novel mechanism of renal blood flow autoregulation and the autoregulatory role of A1 adenosine receptors in miceArmin Just
Dept of Cell and Molecular Physiology, 6341 Medical Biomolecular Research Bldg, CB 7545, School of Medicine, Univ of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7545, USA
Am J Physiol Renal Physiol 293:F1489-500. 2007..A fourth mechanism with kinetics similar to TGF but independent of A1AR and furosemide might also contribute. A1AR mediate classical TGF but not TGF-MR interaction... - Role of angiotensin II in dynamic renal blood flow autoregulation of the conscious dogArmin Just
Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, Med Sci Res Bldg CB7545, Chapel Hill, NC 27599, USA
J Physiol 538:167-77. 2002..Consequently, it appears that ANGII augments not only TGF, but also the myogenic response... - Dynamic characteristics and underlying mechanisms of renal blood flow autoregulation in the conscious dogA Just
Institut fur Physiologie und Pathophysiologie, Universitat Heidelberg, D 69120 Heidelberg, Germany
Am J Physiol Renal Physiol 280:F1062-71. 2001..The three mechanisms contribute about equally to resting RVR. The myogenic response is faster in the kidney than in the hindlimb... 
Reactive oxygen species participate in acute renal vasoconstrictor responses induced by ETA and ETB receptorsArmin Just
Dept of Cell and Molecular Physiology, 6341 Medical Biomolecular Research Bldg, CB 7545, School of Medicine, Univ of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7545, USA
Am J Physiol Renal Physiol 294:F719-28. 2008..This physiological constrictor action of ROS does not depend on scavenging of NO. In contrast, scavenging of O(2)(-) by NO seems to be more important during ET(B) stimulation...- NO and NO-independent mechanisms mediate ETB receptor buffering of ET-1-induced renal vasoconstriction in the ratArmin Just
Dept of Cell and Molecular Physiology, 6341 Medical Biomolecular Research Bldg, CB 7545, School of Medicine, Univ of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7545, USA
Am J Physiol Regul Integr Comp Physiol 288:R1168-77. 2005.... - Tonic and phasic influences of nitric oxide on renal blood flow autoregulation in conscious dogsA Just
I Physiologisches Institut, Ruprecht Karls Universitat Heidelberg, D 69120 Heidelberg, Germany
Am J Physiol 276:F442-9. 1999..The feedback oscillations of the TGF are not affected by NO. NO contributes to the autoregulation below 0.01 Hz due to phasic modulation independent of its mean level... - Large vasodilatations in skeletal muscle of resting conscious dogs and their contribution to blood pressure variabilityA Just
Institut fur Physiologie und Pathophysiologie, Universitat Heidelberg, Im Neuenheimer Feld 326, D 69120 Heidelberg, Germany
J Physiol 527:611-22. 2000..The vasodilatations substantially affect the regulation of skeletal muscle blood flow and explain a significant portion of AP and HR variability... - Buffering of blood pressure variability by the renin-angiotensin system in the conscious dogA Just
I Physiologisches Institut, Ruprecht Karls Universitat Heidelberg, D 69120 Heidelberg, Germany
J Physiol 512:583-93. 1998..Even if the RAS is stimulated by sodium restriction its contribution to short-term blood pressure buffering is only marginal... - Connexin 40 mediates the tubuloglomerular feedback contribution to renal blood flow autoregulationArmin Just
Department of Cell and Molecular Physiology, Carolina Cardiovascular Biology Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
J Am Soc Nephrol 20:1577-85. 2009..However, Cx40 is not required for the modulation of the renal myogenic response by NO, norepinephrine-induced renal vasoconstriction, and acetylcholine- or NO-induced vasodilation... - Autonomic cardiovascular control in conscious miceA Just
Institut fur Physiologie und Pathophysiologie, Universitat Heidelberg, D 69120 Heidelberg, Germany
Am J Physiol Regul Integr Comp Physiol 279:R2214-21. 2000..Limits between frequency ranges are proposed as 0.15 Hz between VLF (very low frequency range) and LF (low frequency range) and 1.5 Hz between LF and HF (high frequency range)... - Thromboxane receptor mediates renal vasoconstriction and contributes to acute renal failure in endotoxemic miceJean-Jacques Boffa
Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, School of Medicine, 6341-B MBRB, Chapel Hill, NC 27599-7545, USA
J Am Soc Nephrol 15:2358-65. 2004..These results demonstrate that renal vasoconstriction during endotoxemic shock induced by LPS is mediated by TP receptors as indicated by pharmacologic blockade and genetic disruption of TP receptors... - Quantification of renal perfusion abnormalities using an intravascular contrast agent (part 2): results in animals and humans with renal artery stenosisStefan O Schoenberg
Department of Radiology, German Cancer Research Center DKFZ, Heidelberg, Germany
Magn Reson Med 49:288-98. 2003..Differentiation between renovascular and renoparenchymal disease thus becomes feasible... - Quantification of renal perfusion using an intravascular contrast agent (part 1): results in a canine modelSilke Aumann
Department of Radiology, German Cancer Research Center (DKFZ, Heidelberg, Germany
Magn Reson Med 49:276-87. 2003..72, P < 0.05) was established. The influence of the arterial input function (AIF), T(1) relaxation effects, and repeated measurements on the precision of the perfusion quantitation is discussed...