C T Jordan

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi request reprint Recent progress in identifying genes regulating hematopoietic stem cell function and fate
    C T Jordan
    Blood and Marrow Transplantation Program Markey Cancer Center University of Kentucky Medical Center 800 Rose Street Room CC405 Lexington KY 40536 USA
    Curr Opin Cell Biol 10:716-20. 1998
  2. ncbi request reprint The use of adenoviral vectors for genetic manipulation and analysis of primitive hematopoietic cells
    C T Jordan
    Division of Hematology Oncology, University of Kentucky Medical Center, Lexington, KY 40536, USA
    Curr Gene Ther 1:257-65. 2001
  3. ncbi request reprint Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells
    M L Guzman
    Blood and Marrow Transplant Program, Markey Cancer Center, Division of Hematology/Oncology, University of Kentucky Medical Center, Lexington, USA
    Blood 97:2177-9. 2001
  4. ncbi request reprint Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
    M L Guzman
    Blood and Marrow Transplant Program, Markey Cancer Center, Division of Hematology/Oncology, University of Kentucky Medical Center, Lexington 40536-0093, USA
    Blood 98:2301-7. 2001
  5. ncbi request reprint Unique molecular and cellular features of acute myelogenous leukemia stem cells
    C T Jordan
    Division of Hematology Oncology, Markey Cancer Center, University of Kentucky Medical Center, Lexington, KY 40536, USA
    Leukemia 16:559-62. 2002

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Recent progress in identifying genes regulating hematopoietic stem cell function and fate
    C T Jordan
    Blood and Marrow Transplantation Program Markey Cancer Center University of Kentucky Medical Center 800 Rose Street Room CC405 Lexington KY 40536 USA
    Curr Opin Cell Biol 10:716-20. 1998
    ..In addition, genetic mapping has identified several loci that correlate strongly with stem cell numbers and proliferation...
  2. ncbi request reprint The use of adenoviral vectors for genetic manipulation and analysis of primitive hematopoietic cells
    C T Jordan
    Division of Hematology Oncology, University of Kentucky Medical Center, Lexington, KY 40536, USA
    Curr Gene Ther 1:257-65. 2001
    ..In this review, we examine recent studies using adenovirus-based vectors as a means to achieve high-level gene transfer into primitive hematopoietic cell types...
  3. ncbi request reprint Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells
    M L Guzman
    Blood and Marrow Transplant Program, Markey Cancer Center, Division of Hematology/Oncology, University of Kentucky Medical Center, Lexington, USA
    Blood 97:2177-9. 2001
    ..Expression of each gene was confirmed by reverse-transcription polymerase chain reaction and immunoblot analysis. It is proposed that tumor-suppressor proteins play a role in the biology of primitive AML cells. (Blood. 2001;97:2177-2179)..
  4. ncbi request reprint Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
    M L Guzman
    Blood and Marrow Transplant Program, Markey Cancer Center, Division of Hematology/Oncology, University of Kentucky Medical Center, Lexington 40536-0093, USA
    Blood 98:2301-7. 2001
    ..Taken together, these data indicate that primitive AML cells aberrantly express NF-kappaB and that the presence of this factor may provide unique opportunities to preferentially ablate LSCs...
  5. ncbi request reprint Unique molecular and cellular features of acute myelogenous leukemia stem cells
    C T Jordan
    Division of Hematology Oncology, Markey Cancer Center, University of Kentucky Medical Center, Lexington, KY 40536, USA
    Leukemia 16:559-62. 2002
    ..This article will summarize data emerging from the study of LSCs and suggest how distinct molecular and cellular characteristics of the LSC population may provide new opportunities for AML therapy...