Christian Jons

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Mutations in conserved amino acids in the KCNQ1 channel and risk of cardiac events in type-1 long-QT syndrome
    Christian Jons
    Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA
    J Cardiovasc Electrophysiol 20:859-65. 2009
  2. ncbi Risk of fatal arrhythmic events in long QT syndrome patients after syncope
    Christian Jons
    Cardiology Division of the Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA
    J Am Coll Cardiol 55:783-8. 2010
  3. ncbi Long QT syndrome in African-Americans
    Thomas Fugate
    Cardiology Division of the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642 8653, USA
    Ann Noninvasive Electrocardiol 15:73-6. 2010
  4. ncbi In silico cardiac risk assessment in patients with long QT syndrome: type 1: clinical predictability of cardiac models
    Ryan Hoefen
    Division of Cardiology, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Rochester, NY 14642, USA
    J Am Coll Cardiol 60:2182-91. 2012
  5. ncbi Mutations in cytoplasmic loops of the KCNQ1 channel and the risk of life-threatening events: implications for mutation-specific response to β-blocker therapy in type 1 long-QT syndrome
    Alon Barsheshet
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circulation 125:1988-96. 2012
  6. ncbi Use of mutant-specific ion channel characteristics for risk stratification of long QT syndrome patients
    Christian Jons
    Cardiology Division, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Sci Transl Med 3:76ra28. 2011
  7. ncbi Long-term implications of cumulative right ventricular pacing among patients with an implantable cardioverter-defibrillator
    Alon Barsheshet
    Cardiology Division, University of Rochester Medical Center, Rochester, New York 14642, USA
    Heart Rhythm 8:212-8. 2011
  8. ncbi Risk of cardiac events in patients with asthma and long-QT syndrome treated with beta(2) agonists
    Princy Thottathil
    Cardiology Division of the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Am J Cardiol 102:871-4. 2008
  9. ncbi Mutation-specific risk in two genetic forms of type 3 long QT syndrome
    Judy F Liu
    Heart Research Follow Up Program, Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA
    Am J Cardiol 105:210-3. 2010
  10. ncbi Long QT syndrome in patients over 40 years of age: increased risk for LQTS-related cardiac events in patients with coronary disease
    Edward Sze
    Cardiology Division, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642 8653, USA
    Ann Noninvasive Electrocardiol 13:327-31. 2008

Collaborators

Detail Information

Publications15

  1. ncbi Mutations in conserved amino acids in the KCNQ1 channel and risk of cardiac events in type-1 long-QT syndrome
    Christian Jons
    Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA
    J Cardiovasc Electrophysiol 20:859-65. 2009
    ..The purpose of this study was to investigate whether KCNQ1 mutations in highly conserved amino acid residues within the voltage-gated potassium channel family are associated with an increased risk of cardiac events...
  2. ncbi Risk of fatal arrhythmic events in long QT syndrome patients after syncope
    Christian Jons
    Cardiology Division of the Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA
    J Am Coll Cardiol 55:783-8. 2010
    ..The aim of this study was to identify risk factors for fatal arrhythmias in long QT syndrome (LQTS) patients presenting with syncope...
  3. ncbi Long QT syndrome in African-Americans
    Thomas Fugate
    Cardiology Division of the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642 8653, USA
    Ann Noninvasive Electrocardiol 15:73-6. 2010
    ..We evaluated the risk factors and clinical course of Long QT syndrome (LQTS) in African-American patients...
  4. ncbi In silico cardiac risk assessment in patients with long QT syndrome: type 1: clinical predictability of cardiac models
    Ryan Hoefen
    Division of Cardiology, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Rochester, NY 14642, USA
    J Am Coll Cardiol 60:2182-91. 2012
    ..The study was designed to assess the ability of computer-simulated electrocardiography parameters to predict clinical outcomes and to risk-stratify patients with long QT syndrome type 1 (LQT1)...
  5. ncbi Mutations in cytoplasmic loops of the KCNQ1 channel and the risk of life-threatening events: implications for mutation-specific response to β-blocker therapy in type 1 long-QT syndrome
    Alon Barsheshet
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circulation 125:1988-96. 2012
    ..We evaluated a possible association between ion channel response to β-adrenergic stimulation and clinical response to β-blocker therapy according to mutation location...
  6. ncbi Use of mutant-specific ion channel characteristics for risk stratification of long QT syndrome patients
    Christian Jons
    Cardiology Division, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Sci Transl Med 3:76ra28. 2011
    ..Our results indicate that genotype and biophysical phenotype analysis may be useful for risk stratification of LQT1 patients and suggest that slow channel activation is associated with an increased risk of cardiac events...
  7. ncbi Long-term implications of cumulative right ventricular pacing among patients with an implantable cardioverter-defibrillator
    Alon Barsheshet
    Cardiology Division, University of Rochester Medical Center, Rochester, New York 14642, USA
    Heart Rhythm 8:212-8. 2011
    ..Limited data regarding the effect of right ventricular pacing (RVP) on long-term survival following implantable cardioverter-defibrillator (ICD) implantation are available...
  8. ncbi Risk of cardiac events in patients with asthma and long-QT syndrome treated with beta(2) agonists
    Princy Thottathil
    Cardiology Division of the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Am J Cardiol 102:871-4. 2008
    ..14, p = 0.05). In conclusion, beta(2)-agonist therapy was associated with an increased risk for cardiac events in patients with asthma with LQTS, and this risk was diminished in patients receiving beta blockers...
  9. ncbi Mutation-specific risk in two genetic forms of type 3 long QT syndrome
    Judy F Liu
    Heart Research Follow Up Program, Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA
    Am J Cardiol 105:210-3. 2010
    ..The findings highlight the importance of knowing the specific mutation in risk stratification of patients with long QT syndrome type 3...
  10. ncbi Long QT syndrome in patients over 40 years of age: increased risk for LQTS-related cardiac events in patients with coronary disease
    Edward Sze
    Cardiology Division, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642 8653, USA
    Ann Noninvasive Electrocardiol 13:327-31. 2008
    ....
  11. ncbi Risk Factors for Recurrent Syncope and Subsequent Fatal or Near-Fatal Events in Children and Adolescents With Long QT Syndrome
    Judy F Liu
    Heart Research Follow Up Program, Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, New York
    J Am Coll Cardiol 57:941-50. 2011
    ..We aimed to identify risk factors for recurrent syncope in children and adolescents with congenital long QT syndrome (LQTS)...
  12. ncbi Influence of diabetes mellitus on outcome in patients over 40 years of age with the long QT syndrome
    Gregory Ouellet
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Am J Cardiol 105:87-9. 2010
    ..In conclusion, diabetes and prolonged QTc interval contributed independent mortality risks in adult patients with LQTS, with no interaction between these 2 risk factors...
  13. ncbi Effect of Metoprolol Versus Carvedilol on Outcomes in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy)
    Martin H Ruwald
    Heart Research Follow Up Program, Cardiology Division, University of Rochester Medical Center, Rochester, New York Department of Cardiology, Gentofte Hospital, Hellerup, Denmark Electronic address
    J Am Coll Cardiol 61:1518-26. 2013
    ..This study sought to compare the effects of metoprolol and carvedilol in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) study...
  14. ncbi Bridging a temporary high risk of sudden arrhythmic death. Experience with the wearable cardioverter defibrillator (WCD)
    Helmut U Klein
    University of Rochester Medical Center, Heart Research Follow Up Program, Rochester, New York 14642, USA
    Pacing Clin Electrophysiol 33:353-67. 2010
    ..Additionally, data are reported on the clinical experience with the WCD based on 354 patients from Germany hospitalized between 2000 and 2008 who wore the WCD for a mean of 3 months...
  15. ncbi Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation
    Sachin S Parikh
    Division of Cardiology, University of Rochester Medical Center, Rochester, New York 14642, USA
    Pacing Clin Electrophysiol 33:532-40. 2010
    ..The purpose of this study was to assess the predictive capability of LA diameter (LAD) and LA volume (LAV) by echocardiography and computed tomography (CT) to determine success in patients undergoing RFCA of AF...