Patricia M Jones

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint The changing face of newborn screening: diagnosis of inborn errors of metabolism by tandem mass spectrometry
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center and Children s Medical Center, 1935 Motor Street, Dallas, TX 75235, USA
    Clin Chim Acta 324:121-8. 2002
  2. ncbi request reprint Accumulation of 3-hydroxy-fatty acids in the culture medium of long-chain L-3-hydroxyacyl CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein-deficient skin fibroblasts: implications for medium chain triglyceride dietary treatment of LCHAD d
    Patricia M Jones
    Department of Pathology, University of Texas, Southwestern Medical Center, Dallas 75235, USA
    Pediatr Res 53:783-7. 2003
  3. ncbi request reprint Effects of odd-numbered medium-chain fatty acids on the accumulation of long-chain 3-hydroxy-fatty acids in long-chain L-3-hydroxyacyl CoA dehydrogenase and mitochondrial trifunctional protein deficient skin fibroblasts
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center, Children s Medical Center of Dallas, Dallas, TX 75235, USA
    Mol Genet Metab 81:96-9. 2004
  4. ncbi request reprint Medium-chain fatty acids undergo elongation before beta-oxidation in fibroblasts
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center, Dalls, TX 75235, USA
    Biochem Biophys Res Commun 346:193-7. 2006
  5. doi request reprint Clinical applications of 3-hydroxy fatty acid analysis by gas chromatography-mass spectrometry
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA
    Biochim Biophys Acta 1811:657-62. 2011
  6. doi request reprint 3-Hydroxy-fatty acid analysis by gas chromatography-mass spectrometry
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center and Children s Medical Center, Dallas, TX, USA
    Methods Mol Biol 603:229-43. 2010
  7. doi request reprint Urine organic acid analysis for inherited metabolic disease using gas chromatography-mass spectrometry
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center and Children s Medical Center, Dallas, TX, USA
    Methods Mol Biol 603:423-31. 2010
  8. ncbi request reprint Addition of quantitative 3-hydroxy-octadecanoic acid to the stable isotope gas chromatography-mass spectrometry method for measuring 3-hydroxy fatty acids
    Patricia M Jones
    University of Texas Southwestern Medical Center, Department of Pathology, and Children s Medical Center of Dallas, Dallas, TX 75235, USA
    Clin Chem 48:176-9. 2002

Detail Information

Publications8

  1. ncbi request reprint The changing face of newborn screening: diagnosis of inborn errors of metabolism by tandem mass spectrometry
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center and Children s Medical Center, 1935 Motor Street, Dallas, TX 75235, USA
    Clin Chim Acta 324:121-8. 2002
  2. ncbi request reprint Accumulation of 3-hydroxy-fatty acids in the culture medium of long-chain L-3-hydroxyacyl CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein-deficient skin fibroblasts: implications for medium chain triglyceride dietary treatment of LCHAD d
    Patricia M Jones
    Department of Pathology, University of Texas, Southwestern Medical Center, Dallas 75235, USA
    Pediatr Res 53:783-7. 2003
    ..Our results suggest that a medium-chain triglyceride preparation that is higher in decanoate may be more effective in reducing the accumulation of potentially toxic long-chain 3-hydroxy-fatty acids in LCHAD deficiency...
  3. ncbi request reprint Effects of odd-numbered medium-chain fatty acids on the accumulation of long-chain 3-hydroxy-fatty acids in long-chain L-3-hydroxyacyl CoA dehydrogenase and mitochondrial trifunctional protein deficient skin fibroblasts
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center, Children s Medical Center of Dallas, Dallas, TX 75235, USA
    Mol Genet Metab 81:96-9. 2004
    ..We found that provision of odd-chain species does decrease the build-up of long-chain FAO intermediates in our in vitro skin fibroblast model, but to a lesser extent than even-numbered MCFAs...
  4. ncbi request reprint Medium-chain fatty acids undergo elongation before beta-oxidation in fibroblasts
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center, Dalls, TX 75235, USA
    Biochem Biophys Res Commun 346:193-7. 2006
    ..This previously undescribed metabolic step may have important implications for the metabolism of medium-chain triglycerides, components in the dietary treatment of a number of disorders...
  5. doi request reprint Clinical applications of 3-hydroxy fatty acid analysis by gas chromatography-mass spectrometry
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA
    Biochim Biophys Acta 1811:657-62. 2011
    ..We have therefore developed an assay to measure these compounds in body fluids, and tissue culture medium to help in the diagnosis of these disorders and to better study the effects of 3-hydroxy fatty acid accumulation...
  6. doi request reprint 3-Hydroxy-fatty acid analysis by gas chromatography-mass spectrometry
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center and Children s Medical Center, Dallas, TX, USA
    Methods Mol Biol 603:229-43. 2010
    ..The method is a stable isotope dilution, electron impact ionization gas chromatography/mass spectrometry (GC/MS) procedure...
  7. doi request reprint Urine organic acid analysis for inherited metabolic disease using gas chromatography-mass spectrometry
    Patricia M Jones
    Department of Pathology, University of Texas Southwestern Medical Center and Children s Medical Center, Dallas, TX, USA
    Methods Mol Biol 603:423-31. 2010
    ..The method utilizes electron impact ionization gas chromatography-mass spectrometry (GC-MS) with total ion collection...
  8. ncbi request reprint Addition of quantitative 3-hydroxy-octadecanoic acid to the stable isotope gas chromatography-mass spectrometry method for measuring 3-hydroxy fatty acids
    Patricia M Jones
    University of Texas Southwestern Medical Center, Department of Pathology, and Children s Medical Center of Dallas, Dallas, TX 75235, USA
    Clin Chem 48:176-9. 2002