Sophie Joly

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. doi request reprint Fungal pathogen recognition by the NLRP3 inflammasome
    Sophie Joly
    Inflammation Program, University of Iowa, Iowa City, IA, USA
    Virulence 1:276-80. 2010
  2. pmc Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans
    Sophie Joly
    Inflammation Program, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    J Immunol 189:4713-7. 2012
  3. pmc Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome
    Sophie Joly
    Division of Infectious Diseases, University of Iowa, Iowa City, IA 52242, USA
    J Immunol 183:3578-81. 2009
  4. pmc Carriage frequency, intensity of carriage, and strains of oral yeast species vary in the progression to oral candidiasis in human immunodeficiency virus-positive individuals
    Kaaren G Vargas
    College of Dentistry, The University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Microbiol 40:341-50. 2002
  5. pmc Racial distribution of Candida dubliniensis colonization among South Africans
    Elaine Blignaut
    Department of Biological Sciences and College of Dentistry, University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Microbiol 41:1838-42. 2003
  6. pmc The NLRP3 inflammasome: a sensor of immune danger signals
    SUZANNE L CASSEL
    Division of Allergy and Immunology, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    Semin Immunol 21:194-8. 2009
  7. ncbi request reprint Candida albicans switch phenotypes display differential levels of fitness
    Keeren Vargas
    The University of Iowa, College of Dentistry, Iowa City, IA 52242, USA
    Med Sci Monit 10:BR198-206. 2004
  8. ncbi request reprint Microevolutionary changes and chromosomal translocations are more frequent at RPS loci in Candida dubliniensis than in Candida albicans
    Sophie Joly
    Department of Biological Sciences, Room 440, University of Iowa, Iowa City, IA 52242, USA
    Infect Genet Evol 2:19-37. 2002
  9. pmc Ca3 fingerprinting of Candida albicans isolates from human immunodeficiency virus-positive and healthy individuals reveals a new clade in South Africa
    Elaine Blignaut
    Department of Biological Sciences, University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Microbiol 40:826-36. 2002
  10. ncbi request reprint Phenotypic switching and filamentation in Candida glabrata
    Salil A Lachke
    Department of Biological Sciences, University of Iowa, Iowa City, IA 52242, USA
    Microbiology 148:2661-74. 2002

Detail Information

Publications11

  1. doi request reprint Fungal pathogen recognition by the NLRP3 inflammasome
    Sophie Joly
    Inflammation Program, University of Iowa, Iowa City, IA, USA
    Virulence 1:276-80. 2010
    ..Here we will review these findings and discuss the role of the NLRP3 inflammasome in initiating an innate immune response to invasive C. albicans...
  2. pmc Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans
    Sophie Joly
    Inflammation Program, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    J Immunol 189:4713-7. 2012
    ..albicans. However, Nlrp10-deficient mice displayed a profound defect in Candida-specific Th1 and Th17 responses. These results demonstrate a novel role for Nlrp10 in the generation of adaptive immune responses to fungal infection...
  3. pmc Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome
    Sophie Joly
    Division of Infectious Diseases, University of Iowa, Iowa City, IA 52242, USA
    J Immunol 183:3578-81. 2009
    ..Nlrp3-deficient mice also demonstrated increased susceptibility to infection with C. albicans, which is consistent with a key role for Nlrp3 in innate immune responses to the pathogen C. albicans...
  4. pmc Carriage frequency, intensity of carriage, and strains of oral yeast species vary in the progression to oral candidiasis in human immunodeficiency virus-positive individuals
    Kaaren G Vargas
    College of Dentistry, The University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Microbiol 40:341-50. 2002
    ..These results suggest that commensal strains colonizing HIV-positive individuals can undergo alterations prior to producing an episode of thrush...
  5. pmc Racial distribution of Candida dubliniensis colonization among South Africans
    Elaine Blignaut
    Department of Biological Sciences and College of Dentistry, University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Microbiol 41:1838-42. 2003
    ..albicans. These results suggest that in South Africa, C. dubliniensis carriage is influenced more by race than by HIV infection status...
  6. pmc The NLRP3 inflammasome: a sensor of immune danger signals
    SUZANNE L CASSEL
    Division of Allergy and Immunology, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    Semin Immunol 21:194-8. 2009
    ..One of the best-studied members of the NLR family is NLRP3 for which a number of divergent activators have recently been described. These and other studies examining the NLRP3 inflammasome will be discussed in this review...
  7. ncbi request reprint Candida albicans switch phenotypes display differential levels of fitness
    Keeren Vargas
    The University of Iowa, College of Dentistry, Iowa City, IA 52242, USA
    Med Sci Monit 10:BR198-206. 2004
    ..It was therefore, the purpose of this study to assess the variability among C. albicans switch phenotypes isolated from a single strain...
  8. ncbi request reprint Microevolutionary changes and chromosomal translocations are more frequent at RPS loci in Candida dubliniensis than in Candida albicans
    Sophie Joly
    Department of Biological Sciences, Room 440, University of Iowa, Iowa City, IA 52242, USA
    Infect Genet Evol 2:19-37. 2002
    ..dubliniensis strains, but not in C. albicans strains, suggesting that RPS clusters may function as recombination hot spots in C. dubliniensis...
  9. pmc Ca3 fingerprinting of Candida albicans isolates from human immunodeficiency virus-positive and healthy individuals reveals a new clade in South Africa
    Elaine Blignaut
    Department of Biological Sciences, University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Microbiol 40:826-36. 2002
    ..Why group SA isolates represent 53 and 33% of colonizing strains in black and white South Africans and are absent in the U.S. collection represents an interesting epidemiological question...
  10. ncbi request reprint Phenotypic switching and filamentation in Candida glabrata
    Salil A Lachke
    Department of Biological Sciences, University of Iowa, Iowa City, IA 52242, USA
    Microbiology 148:2661-74. 2002
    ..Core switching, pseudohypha formation and tube formation occurred in a majority of 62 tested clinical isolates, demonstrating that these developmental programmes are general characteristics of most strains of C. glabrata...
  11. pmc Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms
    Sophie Joly
    Dows Institute for Dental Research, University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Microbiol 42:1024-9. 2004
    ..Finally, the significant variability between strains underlies the importance of testing multiple strains when evaluating activities of antimicrobial peptides...