Ian N Johnston

Summary

Affiliation: University of Colorado
Country: USA

Publications

  1. ncbi request reprint Inhibition of morphine analgesia by LPS: role of opioid and NMDA receptors and spinal glia
    Ian N Johnston
    School of Psychology, Griffith Taylor Building, A19, University of Sydney, Sydney, NSW 2006, Australia
    Behav Brain Res 156:75-83. 2005
  2. ncbi request reprint Acute and conditioned sickness reduces morphine analgesia
    Ian N Johnston
    Department of Psychology, University of Colorado, Boulder, CO 80303 0345, USA
    Behav Brain Res 142:89-97. 2003
  3. ncbi request reprint Inhibition of morphine analgesia by lithium: role of peripheral and central opioid receptors
    Ian N Johnston
    Department of Psychology, University of Colorado, Campus Box 0345, Boulder, CO 80309, USA
    Behav Brain Res 151:151-8. 2004
  4. ncbi request reprint A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine
    Ian N Johnston
    Department of Psychology, University of Colorado, Boulder, Colorado 80309, USA
    J Neurosci 24:7353-65. 2004
  5. ncbi request reprint Glia: novel counter-regulators of opioid analgesia
    Linda R Watkins
    Department of Psychology and the Center for Neuroscience, University of Colorado at Boulder, Boulder, CO 80309 0345, USA
    Trends Neurosci 28:661-9. 2005

Detail Information

Publications5

  1. ncbi request reprint Inhibition of morphine analgesia by LPS: role of opioid and NMDA receptors and spinal glia
    Ian N Johnston
    School of Psychology, Griffith Taylor Building, A19, University of Sydney, Sydney, NSW 2006, Australia
    Behav Brain Res 156:75-83. 2005
    ..These results demonstrate that LPS recruits similar, if not the same mechanisms that reduce morphine tolerance following opiate administration: namely, stimulation of opioid and NMDA receptors and recruitment of spinal glia...
  2. ncbi request reprint Acute and conditioned sickness reduces morphine analgesia
    Ian N Johnston
    Department of Psychology, University of Colorado, Boulder, CO 80303 0345, USA
    Behav Brain Res 142:89-97. 2003
    ..Thus, in addition to provoking hyperalgesia, illness-inducing agents also activate endogenous antianalgesic mechanisms...
  3. ncbi request reprint Inhibition of morphine analgesia by lithium: role of peripheral and central opioid receptors
    Ian N Johnston
    Department of Psychology, University of Colorado, Campus Box 0345, Boulder, CO 80309, USA
    Behav Brain Res 151:151-8. 2004
    ..Thus, activity at peripheral and central opioid receptors is necessary for the inhibition of morphine analgesia by LiCl, but peripheral opioid receptors are not critical for the expression of this inhibition...
  4. ncbi request reprint A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine
    Ian N Johnston
    Department of Psychology, University of Colorado, Boulder, Colorado 80309, USA
    J Neurosci 24:7353-65. 2004
    ..Taken together, these results suggest that IL-1 and fractalkine are endogenous regulators of morphine analgesia and are involved in the increases in pain sensitivity that occur after chronic opiates...
  5. ncbi request reprint Glia: novel counter-regulators of opioid analgesia
    Linda R Watkins
    Department of Psychology and the Center for Neuroscience, University of Colorado at Boulder, Boulder, CO 80309 0345, USA
    Trends Neurosci 28:661-9. 2005
    ..New data suggest that glia also release neuroexcitatory substances in response to morphine, thereby opposing its effects. Controlling glial activation could therefore increase the clinical utility of analgesic drugs...