Daniel Johnston

Summary

Affiliation: University of Texas
Country: USA

Publications

  1. ncbi request reprint Active dendrites: colorful wings of the mysterious butterflies
    Daniel Johnston
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    Trends Neurosci 31:309-16. 2008
  2. pmc The h channel mediates location dependence and plasticity of intrinsic phase response in rat hippocampal neurons
    Rishikesh Narayanan
    Center for Learning and Memory, The University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 28:5846-60. 2008
  3. pmc Loss of functional A-type potassium channels in the dendrites of CA1 pyramidal neurons from a mouse model of fragile X syndrome
    Brandy N Routh
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas 78712
    J Neurosci 33:19442-50. 2013
  4. pmc Temporal synchrony and gamma-to-theta power conversion in the dendrites of CA1 pyramidal neurons
    Sachin P Vaidya
    1 Institute for Neuroscience Graduate Program, The University of Texas at Austin, Austin, Texas, USA 2 Center for Learning and Memory, The University of Texas at Austin, Austin, Texas, USA
    Nat Neurosci 16:1812-20. 2013
  5. ncbi request reprint Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons
    Xixi Chen
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 26:12143-51. 2006
  6. pmc The h current is a candidate mechanism for regulating the sliding modification threshold in a BCM-like synaptic learning rule
    Rishikesh Narayanan
    Center for Learning and Memory, The University of Texas, Austin, Texas 78712 0805, USA
    J Neurophysiol 104:1020-33. 2010
  7. pmc Anatomical and electrophysiological comparison of CA1 pyramidal neurons of the rat and mouse
    Brandy N Routh
    Center for Learning and Memory, University of Texas at Austin, 1 University Station, Austin, Texas 78712, USA
    J Neurophysiol 102:2288-302. 2009
  8. pmc Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus
    Kelly A Dougherty
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    J Neurophysiol 109:1940-53. 2013
  9. pmc Dendritic generation of mGluR-mediated slow afterdepolarization in layer 5 neurons of prefrontal cortex
    Brian E Kalmbach
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 33:13518-32. 2013
  10. pmc Impaired dendritic expression and plasticity of h-channels in the fmr1(-/y) mouse model of fragile X syndrome
    Darrin H Brager
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    Cell Rep 1:225-33. 2012

Research Grants

  1. CELLULAR INFORMATION PROCESSING IN HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 1992
  2. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2003
  3. Modulation of Dendritic K+ Channels in Hippocampus
    Daniel Johnston; Fiscal Year: 2004
  4. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2004
  5. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2005
  6. PHARMACOLOGY OF MOSSY FIBER SYNAPTIC PLASTICITY
    Daniel Johnston; Fiscal Year: 2007
  7. REGULATION OF NEURONAL EXCITABILITY
    Daniel Johnston; Fiscal Year: 2008
  8. PHARMACOLOGY OF MOSSY FIBER SYNAPTIC PLASTICITY
    Daniel Johnston; Fiscal Year: 2008
  9. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2008
  10. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2009

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Active dendrites: colorful wings of the mysterious butterflies
    Daniel Johnston
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    Trends Neurosci 31:309-16. 2008
    ..In this brief historical perspective, we track important milestones in the chameleonic transmogrification of these mysterious butterflies...
  2. pmc The h channel mediates location dependence and plasticity of intrinsic phase response in rat hippocampal neurons
    Rishikesh Narayanan
    Center for Learning and Memory, The University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 28:5846-60. 2008
    ..Our analyses and results also establish impedance as a powerful measure of intrinsic dynamics and excitability, given that it quantifies temporal relationships among signals and excitability as functions of input frequency...
  3. pmc Loss of functional A-type potassium channels in the dendrites of CA1 pyramidal neurons from a mouse model of fragile X syndrome
    Brandy N Routh
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas 78712
    J Neurosci 33:19442-50. 2013
    ..Furthermore, CA1 pyramidal neurons from fmr1-/y mice had a lower threshold for LTP induction. These data suggest that loss of I(KA) in hippocampal neurons may contribute to dendritic pathophysiology in Fragile X syndrome...
  4. pmc Temporal synchrony and gamma-to-theta power conversion in the dendrites of CA1 pyramidal neurons
    Sachin P Vaidya
    1 Institute for Neuroscience Graduate Program, The University of Texas at Austin, Austin, Texas, USA 2 Center for Learning and Memory, The University of Texas at Austin, Austin, Texas, USA
    Nat Neurosci 16:1812-20. 2013
    ....
  5. ncbi request reprint Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons
    Xixi Chen
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 26:12143-51. 2006
    ..2 knock-out and wild-type neurons. Our results support the hypothesis that dendritic A-type K+ channels, composed of Kv4.2 subunits, regulate action potential backpropagation and the induction of specific forms of synaptic plasticity...
  6. pmc The h current is a candidate mechanism for regulating the sliding modification threshold in a BCM-like synaptic learning rule
    Rishikesh Narayanan
    Center for Learning and Memory, The University of Texas, Austin, Texas 78712 0805, USA
    J Neurophysiol 104:1020-33. 2010
    ..Our results underscore the heavy mutual interdependence of synaptic and intrinsic properties/plasticity in regulating learning and homeostasis in single neurons and their networks under both physiological and pathological brain states...
  7. pmc Anatomical and electrophysiological comparison of CA1 pyramidal neurons of the rat and mouse
    Brandy N Routh
    Center for Learning and Memory, University of Texas at Austin, 1 University Station, Austin, Texas 78712, USA
    J Neurophysiol 102:2288-302. 2009
    ..Our findings indicate that comparisons of data obtained across strains or species will need to account for these and potentially other physiological and anatomical differences...
  8. pmc Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus
    Kelly A Dougherty
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    J Neurophysiol 109:1940-53. 2013
    ....
  9. pmc Dendritic generation of mGluR-mediated slow afterdepolarization in layer 5 neurons of prefrontal cortex
    Brian E Kalmbach
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 33:13518-32. 2013
    ..Focal mGluR activation in L5, near the soma or at the border of L1/L2, near the tuft, generates a local sADP. This dendritic depolarization may act synergistically with synaptic input to regulate mnemonic activity in PFC...
  10. pmc Impaired dendritic expression and plasticity of h-channels in the fmr1(-/y) mouse model of fragile X syndrome
    Darrin H Brager
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    Cell Rep 1:225-33. 2012
    ....
  11. ncbi request reprint Activity-dependent decrease of excitability in rat hippocampal neurons through increases in I(h)
    Yuan Fan
    Center for Learning and Memory, University of Texas at Austin, 1 University Station, C7000, Austin, Texas 78712, USA
    Nat Neurosci 8:1542-51. 2005
    ..The occurrence of such a reduction in cellular excitability in parallel with synaptic potentiation would be a negative feedback mechanism to normalize neuronal output firing and thus promote network stability...
  12. pmc Short- and long-term plasticity in CA1 neurons from mice lacking h-channel auxiliary subunit TRIP8b
    Darrin H Brager
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas
    J Neurophysiol 110:2350-7. 2013
    ..These results suggest that the physiological impact of TRIP8b deletion is not restricted to the integrative properties of neurons but also includes both synaptic and intrinsic plasticity...
  13. pmc Projection-specific neuromodulation of medial prefrontal cortex neurons
    Nikolai C Dembrow
    Center for Learning and Memory, The University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 30:16922-37. 2010
    ..Together, these data suggest that the two categories of projection neurons may subserve separate functions in PFC and may be engaged differently during working memory processes...
  14. pmc Kinase-dependent modification of dendritic excitability after long-term potentiation
    J Amiel Rosenkranz
    Center for Learning and Memory, University of Texas at Austin, Austin, TX, USA
    J Physiol 587:115-25. 2009
    ..Furthermore, this study uncovers an additional contribution of kinase activation to plasticity that may occur during learning...
  15. ncbi request reprint Voltage-gated ion channels in dendrites of hippocampal pyramidal neurons
    Xixi Chen
    Center for Learning and Memory, University of Texas at Austin, Austin, TX, 78712, USA
    Pflugers Arch 453:397-401. 2006
    ..In this report, we provide some new evidence for the role of the delayed-rectifier K(+) channel in shaping the dendritic action potential at different membrane potentials...
  16. ncbi request reprint State-dependent modulation of amygdala inputs by dopamine-induced enhancement of sodium currents in layer V entorhinal cortex
    J Amiel Rosenkranz
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 27:7054-69. 2007
    ..Functionally, by enhancement of amygdala inputs that arrive in concert with other inputs, or during depolarized states, DA can facilitate the impact of affect on memory in a subset of conditions...
  17. ncbi request reprint Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons
    Xixi Chen
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 25:3787-92. 2005
    ..Therefore, these channels are GIRK channels, which are constitutively active at rest in the apical dendrites of CA1 pyramidal neurons and can be further activated via G-protein-coupled neurotransmitter receptors...
  18. ncbi request reprint Target cell-dependent normalization of transmitter release at neocortical synapses
    Helmut J Koester
    Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, Jahnstrasse 29, D 69120 Heidelberg, Germany
    Science 308:863-6. 2005
    ..We propose that the mechanisms that regulate the functional properties of boutons of a pyramid normalize the presynaptic Ca2+ influx and release probability for all those boutons that innervate the same target cell...
  19. ncbi request reprint Dopaminergic regulation of neuronal excitability through modulation of Ih in layer V entorhinal cortex
    J Amiel Rosenkranz
    Center for Learning and Memory, University of Texas, Austin, Texas 78712, USA
    J Neurosci 26:3229-44. 2006
    ..The data suggest that DA can directly influence the membrane properties of layer V EC pyramidal neurons by modulation of h-channels. These actions may underlie some of the effects of DA on memory formation...
  20. pmc Intrinsic excitability of CA1 pyramidal neurones from the rat dorsal and ventral hippocampus
    Kelly A Dougherty
    Center for Learning and Memory, University of Texas at Austin, 100 East 24th St Room 4 310, Austin, TX 78712, USA
    J Physiol 590:5707-22. 2012
    ..This difference is likely to predispose the VHC to hyperexcitability...
  21. pmc Calcium store depletion induces persistent perisomatic increases in the functional density of h channels in hippocampal pyramidal neurons
    Rishikesh Narayanan
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    Neuron 68:921-35. 2010
    ..We postulate that this form of depletion-induced intrinsic plasticity is a neuroprotective mechanism that reduces excitability after depletion of calcium stores triggered through altered network activity during pathological conditions...
  22. pmc Species-specific differences in the medial prefrontal projections to the pons between rat and rabbit
    Maria V Moya
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas, 78712
    J Comp Neurol 522:3052-74. 2014
    ..The resulting implications for mPFC or pons manipulations for studies of trace eyeblink in each species are discussed. J. Comp. Neurol. 522:3052-3074, 2014. © 2014 Wiley Periodicals, Inc. ..
  23. pmc Slowly inactivating component of Na+ current in peri-somatic region of hippocampal CA1 pyramidal neurons
    Yul Young Park
    Center for Learning and Memory, Univ of Texas at Austin, Austin, TX 78712 0805, USA
    J Neurophysiol 109:1378-90. 2013
    ..Current-clamp measurements with hexanol suggested that INaS was involved in generation of an action potential and in upregulation of neuronal excitability...
  24. pmc Enhancement of dorsal hippocampal activity by knockdown of HCN1 channels leads to anxiolytic- and antidepressant-like behaviors
    Chung Sub Kim
    Center for Learning and Memory, The Institute for Neuroscience, and Section of Neurobiology University of Texas at Austin, Austin, TX 78712, USA
    Neuron 75:503-16. 2012
    ..Our results suggest that HCN1 protein could be a potential target for treatment of anxiety and depression disorders...
  25. ncbi request reprint The ascent of channels with memory
    Rishikesh Narayanan
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    Neuron 60:735-8. 2008
    ....
  26. pmc VolRoverN: enhancing surface and volumetric reconstruction for realistic dynamical simulation of cellular and subcellular function
    John Edwards
    Department of Computer Science, ICES, The University of Texas, Austin, TX, USA
    Neuroinformatics 12:277-89. 2014
    ....
  27. pmc Channelopathies and dendritic dysfunction in fragile X syndrome
    Darrin H Brager
    Center for Learning and Memory, University of Texas at Austin, Austin, TX 78712, United States Electronic address
    Brain Res Bull 103:11-7. 2014
    ..In this chapter we discuss the role of voltage-gated ion channels in neuronal processing and describe how identified channelopathies in models of fragile X syndrome may play a role in dendritic pathophysiology...
  28. pmc Long-term potentiation in rat hippocampal neurons is accompanied by spatially widespread changes in intrinsic oscillatory dynamics and excitability
    Rishikesh Narayanan
    Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA
    Neuron 56:1061-75. 2007
    ..Our results suggest that the frequency response of these neurons depends on the dendritic location of their inputs and that activity can regulate their response dynamics within an oscillating neural network...
  29. ncbi request reprint Plasticity of intrinsic excitability during long-term depression is mediated through mGluR-dependent changes in I(h) in hippocampal CA1 pyramidal neurons
    Darrin H Brager
    Center for Learning and Memory, University of Texas at Austin, Austin, Texas 78712, USA
    J Neurosci 27:13926-37. 2007
    ..We propose these changes as part of a homeostatic and bidirectional control mechanism for intrinsic excitability during learning...
  30. pmc Active dendrites, potassium channels and synaptic plasticity
    Daniel Johnston
    Division of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Philos Trans R Soc Lond B Biol Sci 358:667-74. 2003
    ..The results support the view that the active properties of dendrites play important roles in synaptic integration and synaptic plasticity of these neurons...
  31. pmc Requirement for hippocampal CA3 NMDA receptors in associative memory recall
    Kazu Nakazawa
    Picower Center for Learning and Memory, RIKEN MIT Neuroscience Research Center, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 297:211-8. 2002
    ..These results provide direct evidence for CA3 NMDA receptor involvement in associative memory recall...
  32. pmc Dendritic K+ channels contribute to spike-timing dependent long-term potentiation in hippocampal pyramidal neurons
    Shigeo Watanabe
    Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 99:8366-71. 2002
    ..These results support the hypothesis that dendritic K(+) channels and the boosting of back-propagating action potentials contribute to the induction of LTP in CA1 neurons...
  33. ncbi request reprint Protein kinase modulation of dendritic K+ channels in hippocampus involves a mitogen-activated protein kinase pathway
    Li Lian Yuan
    Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 22:4860-8. 2002
    ..2 subunits...
  34. ncbi request reprint Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites
    Nicholas P Poolos
    Division of Neuroscience, Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nat Neurosci 5:767-74. 2002
    ..These results demonstrate that neuronal excitability can be altered by drugs acting selectively on dendrites, and suggest an important role for I(h) in controlling dendritic excitability and epileptogenesis...
  35. ncbi request reprint Normalization of Ca2+ signals by small oblique dendrites of CA1 pyramidal neurons
    Andreas Frick
    Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 23:3243-50. 2003
    ..The higher density of I(K(A)) may have important implications for our understanding of synaptic integration and plasticity in these structures...
  36. pmc Photolysis of postsynaptic caged Ca2+ can potentiate and depress mossy fiber synaptic responses in rat hippocampal CA3 pyramidal neurons
    Jun Wang
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    J Neurophysiol 91:1596-607. 2004
    ..Our results are consistent with a postsynaptic locus for the induction of at least some forms of synaptic plasticity at mossy fiber synapses...
  37. ncbi request reprint LTP is accompanied by an enhanced local excitability of pyramidal neuron dendrites
    Andreas Frick
    Division of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nat Neurosci 7:126-35. 2004
    ..These results suggest an important mechanism associated with LTP for shaping signal processing and controlling dendritic function...
  38. ncbi request reprint Calcium-calmodulin-dependent kinase II modulates Kv4.2 channel expression and upregulates neuronal A-type potassium currents
    Andrew W Varga
    Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 24:3643-54. 2004
    ..Thus CaMKII can directly modulate neuronal excitability by increasing cell-surface expression of A-type K(+) channels...
  39. pmc Properties of single voltage-dependent K+ channels in dendrites of CA1 pyramidal neurones of rat hippocampus
    Xixi Chen
    Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    J Physiol 559:187-203. 2004
    ..These results suggest both functional and molecular complexity for K(+) channels in dendrites of CA1 pyramidal neurones...
  40. ncbi request reprint Acquired dendritic channelopathy in temporal lobe epilepsy
    Christophe Bernard
    Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Science 305:532-5. 2004
    ..Kinase inhibition partly reversed dendritic excitability to control levels. Such acquired channelopathy is likely to amplify neuronal activity and may contribute to the initiation and/or propagation of seizures in TLE...
  41. ncbi request reprint Neuroscience. The neuron doctrine, redux
    Theodore H Bullock
    Scripps Institution of Oceanography and Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA
    Science 310:791-3. 2005
  42. pmc Associative pairing enhances action potential back-propagation in radial oblique branches of CA1 pyramidal neurons
    Sonia Gasparini
    Neuroscience Center, Louisiana State University Health Science Center, 2020 Gravier Street, New Orleans, LA 70112, USA
    J Physiol 580:787-800. 2007
    ..We hypothesize that these two signals may be involved in the regulation of the expression and activity of dendritic voltage- and ligand-gated ion channels...
  43. ncbi request reprint Plasticity of dendritic function
    Jeffrey C Magee
    Neuroscience Center, Louisiana State University Health Science Center, 2020 Gravier Street, New Orleans, Louisiana 70112, USA
    Curr Opin Neurobiol 15:334-42. 2005
    ..Indeed, voltage gated ion channel modulation shapes the active properties of neuronal dendrites to specific conditions, thus tailoring the functional role of the single neuron within its circuit...
  44. ncbi request reprint Plasticity of dendritic excitability
    Andreas Frick
    Baylor College of Medicine, Division of Neuroscience, Houston, Texas 77030, USA
    J Neurobiol 64:100-15. 2005
    ..In this review we discuss how this plasticity of dendritic excitability could alter information transfer and processing within dendrites, neurons, and neural networks under physiological and pathological conditions...
  45. ncbi request reprint Channeling a 'funny' side of memory
    Daniel Johnston
    Nat Neurosci 8:134-5. 2005
  46. pmc Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons
    Mala M Shah
    Division of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Neuron 44:495-508. 2004
    ..Our results suggest that dendritic I(h) plays an important role in determining the excitability of EC layer III neurons and their associated neural networks...
  47. ncbi request reprint Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus
    Yong Liang
    Division of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Neurophysiol 87:1132-7. 2002
    ....
  48. ncbi request reprint Acceleration of K+ channel inactivation by MEK inhibitor U0126
    Li Lian Yuan
    Dept of Neuroscience, Univ of Minnesota, 6 145 Jackson Hall, 321 Church St, Minneapolis, MN 55455, USA
    Am J Physiol Cell Physiol 290:C165-71. 2006
    ..Our data favor the conclusion that the increase in the rate of channel inactivation by U0126 is likely to be independent of protein kinase inhibition and instead represents a direct action on channel gating...
  49. ncbi request reprint A modified Sindbis vector for prolonged gene expression in neurons
    Andreas Jeromin
    Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurophysiol 90:2741-5. 2003
    ..In addition, the use of this vector for the functional expression of mammalian voltage-gated ion channels in organotypic slices is demonstrated...
  50. doi request reprint Out of control in the dendrites
    Nelson Spruston
    Nat Neurosci 11:733-4. 2008

Research Grants22

  1. CELLULAR INFORMATION PROCESSING IN HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 1992
    ..potential in the dendrites during synaptic activity? 4) How do dendrites of CA3 neurons integrate and modify incoming synaptic inputs and how do active synapses communicate with other active (and inactive) synapses in the dendrites?..
  2. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2003
    ..We expect that the results of our studies will provide important information about the functional significance of these disease-related changes in dendrites. ..
  3. Modulation of Dendritic K+ Channels in Hippocampus
    Daniel Johnston; Fiscal Year: 2004
    ..The results of these experiments will provide basic information important for studies of temporal lobe epilepsy, Alzheimer's disease, schizophrenia, and depression. ..
  4. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2004
    ..We expect that the results of our studies will provide important information about the functional significance of these disease-related changes in dendrites. ..
  5. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2005
    ..We expect that the results of our studies will provide important information about the functional significance of these disease-related changes in dendrites. ..
  6. PHARMACOLOGY OF MOSSY FIBER SYNAPTIC PLASTICITY
    Daniel Johnston; Fiscal Year: 2007
    ..abstract_text> ..
  7. REGULATION OF NEURONAL EXCITABILITY
    Daniel Johnston; Fiscal Year: 2008
    ....
  8. PHARMACOLOGY OF MOSSY FIBER SYNAPTIC PLASTICITY
    Daniel Johnston; Fiscal Year: 2008
    ..abstract_text> ..
  9. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2008
    ..We expect that the results of our studies will provide important information about the functional significance of these disease-related changes in dendrites. ..
  10. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2009
    ..We expect that the results of our studies will provide important information about the functional significance of these disease-related changes in dendrites. ..
  11. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2002
    ..We expect that the results of our studies will provide important information about the functional significance of these disease-related changes in dendrites. ..
  12. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2001
    ..We expect that the results of our studies will provide important information about the functional significance of these disease-related changes in dendrites. ..
  13. CELLULAR INFORMATION PROCESSING IN HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 1999
    ..It is expected that the results of the study will provide important information about the functional significance of these disease-related changes. ..
  14. CELLULAR INFORMATION PROCESSING IN HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 1991
    ..potential in the dendrites during synaptic activity? 4) How do dendrites of CA3 neurons integrate and modify incoming synaptic inputs and how do active synapses communicate with other active (and inactive) synapses in the dendrites?..
  15. CELLULAR INFORMATION PROCESSING IN HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 1993
    ..potential in the dendrites during synaptic activity? 4) How do dendrites of CA3 neurons integrate and modify incoming synaptic inputs and how do active synapses communicate with other active (and inactive) synapses in the dendrites?..
  16. CELLULAR INFORMATION PROCESSING IN HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2000
    ..It is expected that the results of the study will provide important information about the functional significance of these disease-related changes. ..
  17. CELLULAR INFORMATION PROCESSING IN THE HIPPOCAMPUS
    Daniel Johnston; Fiscal Year: 2010
    ..We expect that the results of our studies will provide important information about the functional significance of these disease-related changes in dendrites. ..